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Volumn 31, Issue 12, 2003, Pages 2990-2994

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CYTIDINE DEAMINASE; CYTOSINE; PLASMID DNA; RIBONUCLEASE; TYROSINE; URACIL; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); DNA;

EID: 0037901850     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg464     Document Type: Article
Times cited : (243)

References (29)
  • 1
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y. and Honjo, T. (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell, 102, 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 2
    • 0037083364 scopus 로고    scopus 로고
    • Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion
    • Arakawa, H., Hauschild, J. and Buerstedde, J.M. (2002) Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion. Science, 295, 1301-1306.
    • (2002) Science , vol.295 , pp. 1301-1306
    • Arakawa, H.1    Hauschild, J.2    Buerstedde, J.M.3
  • 3
    • 0037022540 scopus 로고    scopus 로고
    • AID is essential for immunoglobulin V gene conversion in a cultured B cell line
    • Harris, R.S., Sale, J.E., Petersen-Mahrt, S.K. and Neuberger, M.S. (2002) AID is essential for immunoglobulin V gene conversion in a cultured B cell line. Curr. Biol., 12, 435-438.
    • (2002) Curr. Biol. , vol.12 , pp. 435-438
    • Harris, R.S.1    Sale, J.E.2    Petersen-Mahrt, S.K.3    Neuberger, M.S.4
  • 4
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
    • Petersen-Mahrt, S.K., Harris, R.S. and Neuberger, M.S. (2002) AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature, 418, 99-103.
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 5
    • 0345301871 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
    • Bransteitter, R., Pham, P., Scharff, M.D. and Goodman, M.F. (2003) Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl Acad. Sci. USA, 21, 21.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.21 , pp. 21
    • Bransteitter, R.1    Pham, P.2    Scharff, M.D.3    Goodman, M.F.4
  • 6
    • 0037026512 scopus 로고    scopus 로고
    • Immunology: The roots of antibody diversity
    • Gearhart, P.J. (2002) Immunology: the roots of antibody diversity. Nature, 419, 29-31.
    • (2002) Nature , vol.419 , pp. 29-31
    • Gearhart, P.J.1
  • 7
    • 0035871625 scopus 로고    scopus 로고
    • Increased transcription levels induce higher mutation rates in a hypermutating cell line
    • Bachl, J., Carlson, C., Gray-Schopfer, V., Dessing, M. and Olsson, C. (2001) Increased transcription levels induce higher mutation rates in a hypermutating cell line. J. Immunol., 166, 5051-5057.
    • (2001) J. Immunol. , vol.166 , pp. 5051-5057
    • Bachl, J.1    Carlson, C.2    Gray-Schopfer, V.3    Dessing, M.4    Olsson, C.5
  • 8
    • 0032127810 scopus 로고    scopus 로고
    • Somatic hypermutation in the heavy chain locus correlates with transcription
    • Fukita, Y., Jacobs, H. and Rajewsky, K. (1998) Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity, 9, 105-114.
    • (1998) Immunity , vol.9 , pp. 105-114
    • Fukita, Y.1    Jacobs, H.2    Rajewsky, K.3
  • 9
    • 0029888843 scopus 로고    scopus 로고
    • The molecular basis of somatic hypermutation of immunoglobulin genes
    • Storb, U. (1996) The molecular basis of somatic hypermutation of immunoglobulin genes. Curr. Opin. Immunol., 8, 206-214.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 206-214
    • Storb, U.1
  • 11
    • 0029872907 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes
    • Wagner, S.D. and Neuberger, M.S. (1996) Somatic hypermutation of immunoglobulin genes. Annu. Rev. Immunol., 14, 441-457.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 441-457
    • Wagner, S.D.1    Neuberger, M.S.2
  • 12
    • 0032698070 scopus 로고    scopus 로고
    • The role of the Escherichia coli Mug protein in the removal of uracil and 3, N(4)-ethenocytosine from DNA
    • Lutsenko, E. and Bhagwat, A.S. (1999) The role of the Escherichia coli Mug protein in the removal of uracil and 3, N(4)-ethenocytosine from DNA. J. Biol. Chem., 274, 31034-31038.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31034-31038
    • Lutsenko, E.1    Bhagwat, A.S.2
  • 13
    • 0036956986 scopus 로고    scopus 로고
    • Transcription-dependent increase in multiple classes of base substitution mutations in Escherichia coli
    • Klapacz, J. and Bhagwat, A.S. (2002) Transcription-dependent increase in multiple classes of base substitution mutations in Escherichia coli. J. Bacteriol., 184, 6866-6872.
    • (2002) J. Bacteriol. , vol.184 , pp. 6866-6872
    • Klapacz, J.1    Bhagwat, A.S.2
  • 14
    • 0027977001 scopus 로고
    • Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hot-spots at sites of cytosine methylation in E. coli
    • Wyszynski, M., Gabbara, S. and Bhagwat, A.S. (1994) Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hot-spots at sites of cytosine methylation in E. coli. Proc. Natl Acad. Sci. USA, 91, 1574-1578.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1574-1578
    • Wyszynski, M.1    Gabbara, S.2    Bhagwat, A.S.3
  • 15
    • 0031979122 scopus 로고    scopus 로고
    • Correlation between transcription and C to T mutations in the non-transcribed DNA strand
    • Beletskii, A. and Bhagwat, A.S. (1998) Correlation between transcription and C to T mutations in the non-transcribed DNA strand. Biol. Chem., 379, 549-551.
    • (1998) Biol. Chem. , vol.379 , pp. 549-551
    • Beletskii, A.1    Bhagwat, A.S.2
  • 16
    • 0035685586 scopus 로고    scopus 로고
    • Transcription-induced cytosine-to-thymine mutations are not dependent on sequence context of the target cytosine
    • Beletskii, A. and Bhagwat, A.S. (2001) Transcription-induced cytosine-to-thymine mutations are not dependent on sequence context of the target cytosine. J. Bacteriol., 183, 6491-6493.
    • (2001) J. Bacteriol. , vol.183 , pp. 6491-6493
    • Beletskii, A.1    Bhagwat, A.S.2
  • 17
    • 0025778670 scopus 로고
    • Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives
    • Bartolome, B., Jubete, Y., Martinez, E. and de la Cruz, F. (1991) Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives. Gene, 102, 75-78.
    • (1991) Gene , vol.102 , pp. 75-78
    • Bartolome, B.1    Jubete, Y.2    Martinez, E.3    de la Cruz, F.4
  • 18
    • 0034006621 scopus 로고    scopus 로고
    • Determining mutation rates in bacterial populations
    • Rosche, W.A. and Foster, P.L. (2000) Determining mutation rates in bacterial populations. Methods, 20, 4-17.
    • (2000) Methods , vol.20 , pp. 4-17
    • Rosche, W.A.1    Foster, P.L.2
  • 19
    • 0030462462 scopus 로고    scopus 로고
    • Transcription-induced mutations: Increase in C to T mutations in the non-transcribed strand during transcription in Escherichia coli
    • Beletskii, A. and Bhagwat, A.S. (1996) Transcription-induced mutations: increase in C to T mutations in the non-transcribed strand during transcription in Escherichia coli. Proc. Natl Acad. Sci. USA, 93, 13919-13924.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13919-13924
    • Beletskii, A.1    Bhagwat, A.S.2
  • 20
    • 0037452080 scopus 로고    scopus 로고
    • Transcription-targeted DNA deamination by the AID antibody diversification enzyme
    • Chaudhuri, J., Tian, M., Khuong, C., Chua, K., Pinaud, E. and Alt, F.W. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature, 422, 726-730.
    • (2003) Nature , vol.422 , pp. 726-730
    • Chaudhuri, J.1    Tian, M.2    Khuong, C.3    Chua, K.4    Pinaud, E.5    Alt, F.W.6
  • 21
    • 0038293484 scopus 로고    scopus 로고
    • Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
    • Ramiro, A.R., Stavropoulos, P., Jankovic, M. and Nussenzweig, M.C. (2003) Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nature Immunol., 4, 452-456.
    • (2003) Nature Immunol. , vol.4 , pp. 452-456
    • Ramiro, A.R.1    Stavropoulos, P.2    Jankovic, M.3    Nussenzweig, M.C.4
  • 22
    • 0038375028 scopus 로고    scopus 로고
    • In vitro deamination of cytosine to uracil in single-stranded DNA by APOBEC1
    • in press
    • Petersen-Mahrt, S.K. and Neuberger, M.S. (2003) In vitro deamination of cytosine to uracil in single-stranded DNA by APOBEC1. J. Biol. Chem., in press.
    • (2003) J. Biol. Chem.
    • Petersen-Mahrt, S.K.1    Neuberger, M.S.2
  • 23
    • 0029598833 scopus 로고
    • RNA:DNA complex formation upon transcription of immunoglobulin switch regions: Implications for the mechanism and regulation of class switch recombination
    • Daniels, G.A. and Lieber, M.R. (1995) RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination. Nucleic Acids Res., 23, 5006-5011.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5006-5011
    • Daniels, G.A.1    Lieber, M.R.2
  • 24
    • 0034161406 scopus 로고    scopus 로고
    • Transcription-dependent R-loop formation at mammalian class switch sequences
    • Tracy, R.B. and Lieber, M.R. (2000) Transcription-dependent R-loop formation at mammalian class switch sequences. EMBO J., 19, 1055-1067.
    • (2000) EMBO J. , vol.19 , pp. 1055-1067
    • Tracy, R.B.1    Lieber, M.R.2
  • 25
    • 0037650190 scopus 로고    scopus 로고
    • R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
    • Yu, K., Chedin, F., Hsieh, C.L., Wilson, T.E. and Lieber, M.R. (2003) R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nature Immunol., 4, 442-451.
    • (2003) Nature Immunol. , vol.4 , pp. 442-451
    • Yu, K.1    Chedin, F.2    Hsieh, C.L.3    Wilson, T.E.4    Lieber, M.R.5
  • 26
    • 0028270307 scopus 로고
    • Elements regulating somatic hypermutation of an immunoglobulin kappa gene: Critical role for the intron enhancer/matrix attachment region
    • Betz, A.G., Milstein, C., Gonzalez-Fernandez, A., Pannell, R., Larson, T. and Neuberger, M.S. (1994) Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region. Cell, 77, 239-248.
    • (1994) Cell , vol.77 , pp. 239-248
    • Betz, A.G.1    Milstein, C.2    Gonzalez-Fernandez, A.3    Pannell, R.4    Larson, T.5    Neuberger, M.S.6
  • 27
    • 0030063726 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
    • Peters, A. and Storb, U. (1996) Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity, 4, 57-65.
    • (1996) Immunity , vol.4 , pp. 57-65
    • Peters, A.1    Storb, U.2
  • 29
    • 0031918097 scopus 로고    scopus 로고
    • Progress in understanding the mechanism and consequences of somatic hypermutation
    • Storb, U. (1998) Progress in understanding the mechanism and consequences of somatic hypermutation. Immunol. Rev., 162, 5-11.
    • (1998) Immunol. Rev. , vol.162 , pp. 5-11
    • Storb, U.1


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