-
1
-
-
13444301307
-
Mechanism and control of V(D)J recombination versus class switch recombination: Similarities and differences
-
Dudley DD, Chaudhuri J, Bassing CH, Alt FW (2005) Mechanism and control of V(D)J recombination versus class switch recombination: Similarities and differences. Adv Immunol 86:43-112.
-
(2005)
Adv Immunol
, vol.86
, pp. 43-112
-
-
Dudley, D.D.1
Chaudhuri, J.2
Bassing, C.H.3
Alt, F.W.4
-
2
-
-
0019731150
-
Rearrangements of immunoglobulin genes during differentiation and evolution
-
Honjo T, et al. (1981) Rearrangements of immunoglobulin genes during differentiation and evolution. Immunol Rev 59:33-67.
-
(1981)
Immunol Rev
, vol.59
, pp. 33-67
-
-
Honjo, T.1
-
3
-
-
0020977742
-
Immunoglobulin genes
-
Honjo T (1983) Immunoglobulin genes. Annu Rev Immunol 1:499-528.
-
(1983)
Annu Rev Immunol
, vol.1
, pp. 499-528
-
-
Honjo, T.1
-
4
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, et al. (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
-
5
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
-
Revy P, et al. (2000) Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 102:565-575.
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
-
6
-
-
3142765336
-
Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri J, Alt FW (2004) Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair. Nat Rev Immunol 4:541-552.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 541-552
-
-
Chaudhuri, J.1
Alt, F.W.2
-
7
-
-
34249794280
-
Evolution of the immunoglobulin heavy chain class switch recombination mechanism
-
Chaudhuri J, et al. (2007) Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Adv Immunol 94:157-214.
-
(2007)
Adv Immunol
, vol.94
, pp. 157-214
-
-
Chaudhuri, J.1
-
8
-
-
0029931447
-
Immunoglobulin class switching
-
Stavnezer J (1996) Immunoglobulin class switching. Curr Opin Immunol 8:199-205.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 199-205
-
-
Stavnezer, J.1
-
9
-
-
34249790004
-
Molecular mechanisms of antibody somatic hypermutation
-
Di Noia JM, Neuberger MS (2007) Molecular mechanisms of antibody somatic hypermutation. Annu Rev Biochem 76:1-22.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 1-22
-
-
Di Noia, J.M.1
Neuberger, M.S.2
-
10
-
-
0347758541
-
The generation of antibody diversity through somatic hypermutation and class switch recombination
-
Li Z, Woo CJ, Iglesias-Ussel MD, Ronai D, Scharff MD (2004) The generation of antibody diversity through somatic hypermutation and class switch recombination. Genes Dev 18:1-11.
-
(2004)
Genes Dev
, vol.18
, pp. 1-11
-
-
Li, Z.1
Woo, C.J.2
Iglesias-Ussel, M.D.3
Ronai, D.4
Scharff, M.D.5
-
11
-
-
63149179802
-
Balancing AID and DNA repair during somatic hypermutation
-
Liu M, Schatz DG (2009) Balancing AID and DNA repair during somatic hypermutation. Trends Immunol 30:173-181.
-
(2009)
Trends Immunol
, vol.30
, pp. 173-181
-
-
Liu, M.1
Schatz, D.G.2
-
13
-
-
2342508343
-
Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat
-
Khamlichi AA, et al. (2004) Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat. Blood 103:3828-3836.
-
(2004)
Blood
, vol.103
, pp. 3828-3836
-
-
Khamlichi, A.A.1
-
14
-
-
0035862327
-
The mu switch region tandem repeats are important, but not required, for antibody class switch recombination
-
Luby TM, Schrader CE, Stavnezer J, Selsing E (2001) The mu switch region tandem repeats are important, but not required, for antibody class switch recombination. J Exp Med 193:159-168.
-
(2001)
J Exp Med
, vol.193
, pp. 159-168
-
-
Luby, T.M.1
Schrader, C.E.2
Stavnezer, J.3
Selsing, E.4
-
15
-
-
0038664358
-
The influence of transcriptional orientation on endogenous switch region function
-
Shinkura R, et al. (2003) The influence of transcriptional orientation on endogenous switch region function. Nat Immunol 4:435-441.
-
(2003)
Nat Immunol
, vol.4
, pp. 435-441
-
-
Shinkura, R.1
-
16
-
-
33846606769
-
Antibody class switching mediated by yeast endonuclease-generated DNA breaks
-
Zarrin AA, et al. (2007) Antibody class switching mediated by yeast endonuclease-generated DNA breaks. Science 315:377-381.
-
(2007)
Science
, vol.315
, pp. 377-381
-
-
Zarrin, A.A.1
-
17
-
-
0037452080
-
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
-
Chaudhuri J, et al. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 422:726-730.
-
(2003)
Nature
, vol.422
, pp. 726-730
-
-
Chaudhuri, J.1
-
18
-
-
4344700569
-
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets
-
Chaudhuri J, Khuong C, Alt FW (2004) Replication protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature 430:992-998.
-
(2004)
Nature
, vol.430
, pp. 992-998
-
-
Chaudhuri, J.1
Khuong, C.2
Alt, F.W.3
-
19
-
-
34547873538
-
Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region
-
Huang FT, et al. (2007) Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region. Mol Cell Biol 27:5921-5932.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5921-5932
-
-
Huang, F.T.1
-
20
-
-
0037650190
-
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
-
Yu K, Chedin F, Hsieh CL, Wilson TE, Lieber MR (2003) R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat Immunol 4:442-451.
-
(2003)
Nat Immunol
, vol.4
, pp. 442-451
-
-
Yu, K.1
Chedin, F.2
Hsieh, C.L.3
Wilson, T.E.4
Lieber, M.R.5
-
21
-
-
23944431983
-
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
-
Schrader CE, Linehan EK, Mochegova SN, Woodland RT, Stavnezer J (2005) Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med 202:561-568.
-
(2005)
J Exp Med
, vol.202
, pp. 561-568
-
-
Schrader, C.E.1
Linehan, E.K.2
Mochegova, S.N.3
Woodland, R.T.4
Stavnezer, J.5
-
22
-
-
0033566999
-
Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes
-
Stavnezer J, et al. (1999) Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes. J Immunol 163:2028-2040.
-
(1999)
J Immunol
, vol.163
, pp. 2028-2040
-
-
Stavnezer, J.1
-
23
-
-
0020038653
-
Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line
-
Alt FW, Rosenberg N, Casanova RJ, Thomas E, Baltimore D (1982) Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line. Nature 296:325-331.
-
(1982)
Nature
, vol.296
, pp. 325-331
-
-
Alt, F.W.1
Rosenberg, N.2
Casanova, R.J.3
Thomas, E.4
Baltimore, D.5
-
24
-
-
0037162518
-
Internal IgH class switch region deletions are positionindependent and enhanced by AID expression
-
Dudley DD, et al. (2002) Internal IgH class switch region deletions are positionindependent and enhanced by AID expression. Proc Natl Acad Sci USA 99:9984-9989.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9984-9989
-
-
Dudley, D.D.1
-
25
-
-
33846340098
-
Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells
-
Reina-San-Martin B, Chen J, Nussenzweig A, Nussenzweig MC (2007) Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells. Eur J Immunol 37:235-239.
-
(2007)
Eur J Immunol
, vol.37
, pp. 235-239
-
-
Reina-San-Martin, B.1
Chen, J.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
26
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
Reina-San-Martin B, et al. (2003) H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J Exp Med 197:1767-1778.
-
(2003)
J Exp Med
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
-
27
-
-
77649249891
-
Alternative End-joining Catalyzes Robust IgH Locus Deletions and Translocations in the Combined Absence of Ligase 4 and Ku
-
in press
-
Boboila C, et al. (2009) Alternative End-joining Catalyzes Robust IgH Locus Deletions and Translocations in the Combined Absence of Ligase 4 and Ku. Proc Natl Acad Sci USA, in press.
-
(2009)
Proc Natl Acad Sci USA
-
-
Boboila, C.1
-
28
-
-
8644238314
-
ATM is required for efficient recombination between immunoglobulin switch regions
-
Reina-San-Martin B, Chen HT, Nussenzweig A, Nussenzweig MC (2004) ATM is required for efficient recombination between immunoglobulin switch regions. J Exp Med 200:1103-1110.
-
(2004)
J Exp Med
, vol.200
, pp. 1103-1110
-
-
Reina-San-Martin, B.1
Chen, H.T.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
29
-
-
0242473148
-
Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination
-
Schrader CE, et al. (2003) Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination. EMBO J 22:5893-5903.
-
(2003)
EMBO J
, vol.22
, pp. 5893-5903
-
-
Schrader, C.E.1
-
30
-
-
33748443257
-
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/-ung-/-mice
-
Xue K, Rada C, Neuberger MS (2006) The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/-ung-/-mice. J Exp Med 203:2085-2094.
-
(2006)
J Exp Med
, vol.203
, pp. 2085-2094
-
-
Xue, K.1
Rada, C.2
Neuberger, M.S.3
-
31
-
-
59649083970
-
Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination
-
Du L, et al. (2008) Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination. J Exp Med 205:3031-3040.
-
(2008)
J Exp Med
, vol.205
, pp. 3031-3040
-
-
Du, L.1
-
32
-
-
0027285726
-
IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predominantly through sequential switching
-
Mandler R, Finkelman FD, Levine AD, Snapper CM (1993) IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predominantly through sequential switching. J Immunol 150:407-418.
-
(1993)
J Immunol
, vol.150
, pp. 407-418
-
-
Mandler, R.1
Finkelman, F.D.2
Levine, A.D.3
Snapper, C.M.4
-
33
-
-
0028984059
-
Human Ig S gamma regions and their participation in sequential switching to IgE
-
Mills FC, Mitchell MP, Harindranath N, Max EE (1995) Human Ig S gamma regions and their participation in sequential switching to IgE. J Immunol 155:3021-3036.
-
(1995)
J Immunol
, vol.155
, pp. 3021-3036
-
-
Mills, F.C.1
Mitchell, M.P.2
Harindranath, N.3
Max, E.E.4
-
34
-
-
0023814675
-
IL-4 induces coexpression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide
-
Snapper CM, Finkelman FD, Stefany D, Conrad DH, Paul WE (1988) IL-4 induces coexpression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide. J Immunol 141:489-498.
-
(1988)
J Immunol
, vol.141
, pp. 489-498
-
-
Snapper, C.M.1
Finkelman, F.D.2
Stefany, D.3
Conrad, D.H.4
Paul, W.E.5
-
35
-
-
0027280936
-
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
-
Gu H, Zou YR, Rajewsky K (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73:1155-1164.
-
(1993)
Cell
, vol.73
, pp. 1155-1164
-
-
Gu, H.1
Zou, Y.R.2
Rajewsky, K.3
-
36
-
-
0033005572
-
Epitope-dependent synergism and antagonism between CD40 antibodies and soluble CD40 ligand for the regulation of CD23 expression and IgE synthesis in human B cells
-
Challa A, Pound JD, Armitage RJ, Gordon J (1999) Epitope-dependent synergism and antagonism between CD40 antibodies and soluble CD40 ligand for the regulation of CD23 expression and IgE synthesis in human B cells. Allergy 54:576-583.
-
(1999)
Allergy
, vol.54
, pp. 576-583
-
-
Challa, A.1
Pound, J.D.2
Armitage, R.J.3
Gordon, J.4
-
37
-
-
62449135436
-
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice
-
Cheng HL, et al. (2009) Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. Proc Natl Acad Sci USA 106:2717-2722.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2717-2722
-
-
Cheng, H.L.1
-
38
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
Yan CT, et al. (2007) IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449:478-482.
-
(2007)
Nature
, vol.449
, pp. 478-482
-
-
Yan, C.T.1
-
39
-
-
0028233142
-
A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
-
Cogné M, et al. (1994) A class switch control region at the 3′ end of the immunoglobulin heavy chain locus. Cell 77:737-747.
-
(1994)
Cell
, vol.77
, pp. 737-747
-
-
Cogné, M.1
-
40
-
-
0033021138
-
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus
-
Seidl KJ, et al. (1999) Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus. Proc Natl Acad Sci USA 96:3000-3005.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3000-3005
-
-
Seidl, K.J.1
-
41
-
-
66349101604
-
G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter
-
Roy D, Lieber MR (2009) G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter. Mol Cell Biol 29:3124-3133.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3124-3133
-
-
Roy, D.1
Lieber, M.R.2
-
42
-
-
73649101345
-
-
Roy D, Zhang Z, Lu Z, Hsieh CL, Lieber MR (2010) Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: A nick can serve as a strong R-loop initiation site. Mol Cell Biol 30:146-159.
-
Roy D, Zhang Z, Lu Z, Hsieh CL, Lieber MR (2010) Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: A nick can serve as a strong R-loop initiation site. Mol Cell Biol 30:146-159.
-
-
-
|