Role of genomic instability and p53 in AID-induced c-myc-Igh translocations

Nature

Volumn 440, Issue 7080, 2006, Pages 105-109

  Ramiro, Almudena R ^a,f   Jankovic, Mila ^a   Callen, Elsa ^c   Difilippantonio, Simone ^c   Chen, Hua Tang ^c   McBride, Kevin M ^a   Eisenreich, Thomas R ^a   Chen, Junjie ^d   Dickins, Ross A ^b,e   Lowe, Scott W ^b,e   Nussenzweig, Andre ^c   Nussenzweig, Michel C ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d MAYO CLINIC   (United States)

^e Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^f CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; DNA; ENZYMES; MOLECULAR BIOLOGY; PROTEINS;

ACTIVATION-INDUCED CYTIDINE DEAMINASE (AID); CHROMOSOMAL LESIONS; CHROMOSOMAL TRANSLOCATIONS; IMMUNOGLOBULIN;

GENES;

ATM PROTEIN; CYTOSINE; DEAMINASE; DNA; HISTONE; IMMUNOGLOBULIN; MYC PROTEIN; NIBRIN; PROTEIN P19; PROTEIN P53; URACIL DNA GLYCOSYLTRANSFERASE;

GENOME;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CHROMOSOME TRANSLOCATION; DNA DAMAGE; ENZYME ACTIVATION; GENE LOCUS; GENOMIC INSTABILITY; MOUSE; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALIA;

EID: 33644643189     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04495     Document Type: Article

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