메뉴 건너뛰기




Volumn 118, Issue 4, 2004, Pages 431-438

AID is required for c-myc/IgH chromosome translocations in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; INTERLEUKIN 6; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); IMMUNOGLOBULIN; IMMUNOGLOBULIN G; MYC PROTEIN;

EID: 4644257592     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2004.08.006     Document Type: Article
Times cited : (404)

References (59)
  • 2
    • 0020529709 scopus 로고
    • Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas
    • Adams J.M., Gerondakis S., Webb E., Corcoran L.M., Cory S. Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. Proc. Natl. Acad. Sci. USA. 80:1983;1982-1986
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 1982-1986
    • Adams, J.M.1    Gerondakis, S.2    Webb, E.3    Corcoran, L.M.4    Cory, S.5
  • 4
    • 0142107802 scopus 로고    scopus 로고
    • Malignancies of lymphoid cells
    • E. Braunwald, A. Fauci, D. Kasper, S. Hauser, D. Longo, & J. Jameson. New York: McGraw-Hill
    • Armitage J.O., Longo D.L. Malignancies of lymphoid cells. Braunwald E., Fauci A., Kasper D., Hauser S., Longo D., Jameson J. Harrison's Principles of Internal Medicine. 2001;715-727 McGraw-Hill, New York
    • (2001) Harrison's Principles of Internal Medicine , pp. 715-727
    • Armitage, J.O.1    Longo, D.L.2
  • 6
    • 0020470134 scopus 로고
    • Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas
    • Crews S., Barth R., Hood L., Prehn J., Calame K. Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science. 218:1982;1319-1321
    • (1982) Science , vol.218 , pp. 1319-1321
    • Crews, S.1    Barth, R.2    Hood, L.3    Prehn, J.4    Calame, K.5
  • 7
    • 0020680903 scopus 로고
    • Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas
    • Dalla-Favera R., Martinotti S., Gallo R.C., Erikson J., Croce C.M. Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas. Science. 219:1983;963-967
    • (1983) Science , vol.219 , pp. 963-967
    • Dalla-Favera, R.1    Martinotti, S.2    Gallo, R.C.3    Erikson, J.4    Croce, C.M.5
  • 9
    • 0037026482 scopus 로고    scopus 로고
    • Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
    • Di Noia J., Neuberger M.S. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature. 419:2002;43-48
    • (2002) Nature , vol.419 , pp. 43-48
    • Di Noia, J.1    Neuberger, M.S.2
  • 10
    • 0033564878 scopus 로고    scopus 로고
    • Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: Parallels with somatic hypermutation
    • Ehrenstein M.R., Neuberger M.S. Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination. parallels with somatic hypermutation EMBO J. 18:1999;3484-3490
    • (1999) EMBO J. , vol.18 , pp. 3484-3490
    • Ehrenstein, M.R.1    Neuberger, M.S.2
  • 12
    • 0027758631 scopus 로고
    • Chromosomal translocations in leukaemia
    • Gauwerky C.E., Croce C.M. Chromosomal translocations in leukaemia. Semin. Cancer Biol. 4:1993;333-340
    • (1993) Semin. Cancer Biol. , vol.4 , pp. 333-340
    • Gauwerky, C.E.1    Croce, C.M.2
  • 13
    • 0020580225 scopus 로고
    • Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene
    • Hamlyn P.H., Rabbitts T.H. Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene. Nature. 304:1983;135-139
    • (1983) Nature , vol.304 , pp. 135-139
    • Hamlyn, P.H.1    Rabbitts, T.H.2
  • 14
    • 0008411148 scopus 로고
    • Organization of immunoglobulin heavy chain genes and allelic deletion model
    • Honjo T., Kataoka T. Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc. Natl. Acad. Sci. USA. 75:1978;2140-2144
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 2140-2144
    • Honjo, T.1    Kataoka, T.2
  • 15
    • 0025345212 scopus 로고
    • Circular DNA is excised by immunoglobulin class switch recombination
    • Iwasato T., Shimizu A., Honjo T., Yamagishi H. Circular DNA is excised by immunoglobulin class switch recombination. Cell. 62:1990;143-149
    • (1990) Cell , vol.62 , pp. 143-149
    • Iwasato, T.1    Shimizu, A.2    Honjo, T.3    Yamagishi, H.4
  • 16
    • 0033526760 scopus 로고    scopus 로고
    • Different mismatch repair deficiencies all have the same effects on somatic hypermutation: Intact primary mechanism accompanied by secondary modifications
    • Kim N., Bozek G., Lo J.C., Storb U. Different mismatch repair deficiencies all have the same effects on somatic hypermutation. intact primary mechanism accompanied by secondary modifications J. Exp. Med. 190:1999;21-30
    • (1999) J. Exp. Med. , vol.190 , pp. 21-30
    • Kim, N.1    Bozek, G.2    Lo, J.C.3    Storb, U.4
  • 17
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler K.W., Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature. 386:1997;761
    • (1997) Nature , vol.386 , pp. 761
    • Kinzler, K.W.1    Vogelstein, B.2
  • 18
    • 0030687580 scopus 로고    scopus 로고
    • Deletional remodeling of c-myc-deregulating chromosomal translocations
    • Kovalchuk A.L., Muller J.R., Janz S. Deletional remodeling of c-myc-deregulating chromosomal translocations. Oncogene. 15:1997;2369-2377
    • (1997) Oncogene , vol.15 , pp. 2369-2377
    • Kovalchuk, A.L.1    Muller, J.R.2    Janz, S.3
  • 19
    • 0034081363 scopus 로고    scopus 로고
    • Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc
    • a
    • Kovalchuk A.L., Kishimoto T., Janz S. Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc. Leukemia. 14:2000;1127-1135. a
    • (2000) Leukemia , vol.14 , pp. 1127-1135
    • Kovalchuk, A.L.1    Kishimoto, T.2    Janz, S.3
  • 20
    • 0034055667 scopus 로고    scopus 로고
    • Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations
    • b
    • Kovalchuk A.L., Mushinski E.B., Janz S. Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations. Leukemia. 14:2000;909-921. b
    • (2000) Leukemia , vol.14 , pp. 909-921
    • Kovalchuk, A.L.1    Mushinski, E.B.2    Janz, S.3
  • 22
    • 0035839959 scopus 로고    scopus 로고
    • Mechanisms of chromosomal translocations in B cell lymphomas
    • Kuppers R., Dalla-Favera R. Mechanisms of chromosomal translocations in B cell lymphomas. Oncogene. 20:2001;5580-5594
    • (2001) Oncogene , vol.20 , pp. 5580-5594
    • Kuppers, R.1    Dalla-Favera, R.2
  • 26
    • 0020700023 scopus 로고
    • Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia
    • Marcu K.B., Harris L.J., Stanton L.W., Erikson J., Watt R., Croce C.M. Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia. Proc. Natl. Acad. Sci. USA. 80:1983;519-523
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 519-523
    • Marcu, K.B.1    Harris, L.J.2    Stanton, L.W.3    Erikson, J.4    Watt, R.5    Croce, C.M.6
  • 27
    • 0025369706 scopus 로고
    • Switch circular DNA formed in cytokine-treated mouse splenocytes: Evidence for intramolecular DNA deletion in immunoglobulin class switching
    • Matsuoka M., Yoshida K., Maeda T., Usuda S., Sakano H. Switch circular DNA formed in cytokine-treated mouse splenocytes. evidence for intramolecular DNA deletion in immunoglobulin class switching Cell. 62:1990;135-142
    • (1990) Cell , vol.62 , pp. 135-142
    • Matsuoka, M.1    Yoshida, K.2    Maeda, T.3    Usuda, S.4    Sakano, H.5
  • 29
    • 0030891628 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6
    • Morse L., Chen D., Franklin D., Xiong Y., Chen-Kiang S. Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6. Immunity. 6:1997;47-56
    • (1997) Immunity , vol.6 , pp. 47-56
    • Morse, L.1    Chen, D.2    Franklin, D.3    Xiong, Y.4    Chen-Kiang, S.5
  • 30
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu M., Sankaranand V.S., Anant S., Sugai M., Kinoshita K., Davidson N.O., Honjo T. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274:1999;18470-18476
    • (1999) J. Biol. Chem. , vol.274 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3    Sugai, M.4    Kinoshita, K.5    Davidson, N.O.6    Honjo, T.7
  • 31
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:2000;553-563
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 32
    • 0034684682 scopus 로고    scopus 로고
    • Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction
    • Müschen M., Re D., Jungnickel B., Diehl V., Rajewsky K., Küppers R. Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction. J. Exp. Med. 192:2000;1833-1840
    • (2000) J. Exp. Med. , vol.192 , pp. 1833-1840
    • Müschen, M.1    Re, D.2    Jungnickel, B.3    Diehl, V.4    Rajewsky, K.5    Küppers, R.6
  • 33
  • 37
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
    • Petersen-Mahrt S.K., Harris R.S., Neuberger M.S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 418:2002;99-103
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 38
    • 0038336667 scopus 로고    scopus 로고
    • Neoplastic development in plasma cells
    • Potter M. Neoplastic development in plasma cells. Immunol. Rev. 194:2003;177-195
    • (2003) Immunol. Rev. , vol.194 , pp. 177-195
    • Potter, M.1
  • 39
    • 0026767880 scopus 로고
    • Plasmacytomagenesis in mice: Model of neoplastic development dependent upon chromosomal translocations
    • Potter M., Wiener F. Plasmacytomagenesis in mice. model of neoplastic development dependent upon chromosomal translocations Carcinogenesis. 13:1992;1681-1697
    • (1992) Carcinogenesis , vol.13 , pp. 1681-1697
    • Potter, M.1    Wiener, F.2
  • 40
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts T.H. Chromosomal translocations in human cancer. Nature. 372:1994;143-149
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 41
    • 0037108463 scopus 로고    scopus 로고
    • Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
    • Rada C., Williams G.T., Nilsen H., Barnes D.E., Lindahl T., Neuberger M.S. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 12:2002;1748-1755
    • (2002) Curr. Biol. , vol.12 , pp. 1748-1755
    • Rada, C.1    Williams, G.T.2    Nilsen, H.3    Barnes, D.E.4    Lindahl, T.5    Neuberger, M.S.6
  • 43
    • 0026443954 scopus 로고
    • Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
    • Rogozin I.B., Kolchanov N.A. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim. Biophys. Acta. 1171:1992;11-18
    • (1992) Biochim. Biophys. Acta , vol.1171 , pp. 11-18
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 44
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching
    • Rolink A., Melchers F., Andersson J. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity. 5:1996;319-330
    • (1996) Immunity , vol.5 , pp. 319-330
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 45
    • 0026792892 scopus 로고
    • V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • a
    • Roth D.B., Menetski J.P., Nakajima P.B., Bosma M.J., Gellert M. V(D)J recombination. broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes Cell. 70:1992;983-991. a
    • (1992) Cell , vol.70 , pp. 983-991
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.B.3    Bosma, M.J.4    Gellert, M.5
  • 46
    • 0026762509 scopus 로고
    • V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor delta rearrangement signals
    • b
    • Roth D.B., Nakajima P.B., Menetski J.P., Bosma M.J., Gellert M. V(D)J recombination in mouse thymocytes. double-strand breaks near T cell receptor delta rearrangement signals Cell. 69:1992;41-53. b
    • (1992) Cell , vol.69 , pp. 41-53
    • Roth, D.B.1    Nakajima, P.B.2    Menetski, J.P.3    Bosma, M.J.4    Gellert, M.5
  • 47
    • 0033517129 scopus 로고    scopus 로고
    • Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes
    • Schrader C.E., Edelmann W., Kucherlapati R., Stavnezer J. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. J. Exp. Med. 190:1999;323-330
    • (1999) J. Exp. Med. , vol.190 , pp. 323-330
    • Schrader, C.E.1    Edelmann, W.2    Kucherlapati, R.3    Stavnezer, J.4
  • 48
    • 0037017390 scopus 로고    scopus 로고
    • Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions
    • Schrader C.E., Vardo J., Stavnezer J. Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J. Exp. Med. 195:2002;367-373
    • (2002) J. Exp. Med. , vol.195 , pp. 367-373
    • Schrader, C.E.1    Vardo, J.2    Stavnezer, J.3
  • 49
    • 2642623612 scopus 로고    scopus 로고
    • Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
    • Shen H.M., Peters A., Baron B., Zhu X., Storb U. Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science. 280:1998;1750-1752
    • (1998) Science , vol.280 , pp. 1750-1752
    • Shen, H.M.1    Peters, A.2    Baron, B.3    Zhu, X.4    Storb, U.5
  • 51
    • 0020582671 scopus 로고
    • Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas
    • Stanton L.W., Watt R., Marcu K.B. Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas. Nature. 303:1983;401-406
    • (1983) Nature , vol.303 , pp. 401-406
    • Stanton, L.W.1    Watt, R.2    Marcu, K.B.3
  • 53
    • 0001292985 scopus 로고
    • Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
    • Taub R., Kirsch I., Morton C., Lenoir G., Swan D., Tronick S., Aaronson S., Leder P. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. USA. 79:1982;7837-7841
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 7837-7841
    • Taub, R.1    Kirsch, I.2    Morton, C.3    Lenoir, G.4    Swan, D.5    Tronick, S.6    Aaronson, S.7    Leder, P.8
  • 54
    • 0025307495 scopus 로고
    • Circular DNA is a product of the immunoglobulin class switch rearrangement
    • von Schwedler U., Jack H.M., Wabl M. Circular DNA is a product of the immunoglobulin class switch rearrangement. Nature. 345:1990;452-456
    • (1990) Nature , vol.345 , pp. 452-456
    • Von Schwedler, U.1    Jack, H.M.2    Wabl, M.3
  • 55
    • 0030959717 scopus 로고    scopus 로고
    • Speed congenics: A classic technique in the fast lane (relatively speaking)
    • Wakeland E., Morel L., Achey K., Yui M., Longmate J. Speed congenics. a classic technique in the fast lane (relatively speaking) Immunol. Today. 18:1997;472-477
    • (1997) Immunol. Today , vol.18 , pp. 472-477
    • Wakeland, E.1    Morel, L.2    Achey, K.3    Yui, M.4    Longmate, J.5
  • 56
    • 0034614916 scopus 로고    scopus 로고
    • Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
    • Wiesendanger M., Kneitz B., Edelmann W., Scharff M.D. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J. Exp. Med. 191:2000;579-584
    • (2000) J. Exp. Med. , vol.191 , pp. 579-584
    • Wiesendanger, M.1    Kneitz, B.2    Edelmann, W.3    Scharff, M.D.4
  • 57
    • 0031278299 scopus 로고    scopus 로고
    • Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination
    • Wuerffel R.A., Du J., Thompson R.J., Kenter A.L. Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination. J. Immunol. 159:1997;4139-4144
    • (1997) J. Immunol. , vol.159 , pp. 4139-4144
    • Wuerffel, R.A.1    Du, J.2    Thompson, R.J.3    Kenter, A.L.4
  • 59
    • 0037188898 scopus 로고    scopus 로고
    • Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
    • Zhu C., Mills K.D., Ferguson D.O., Lee C., Manis J., Fleming J., Gao Y., Morton C.C., Alt F.W. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell. 109:2002;811-821
    • (2002) Cell , vol.109 , pp. 811-821
    • Zhu, C.1    Mills, K.D.2    Ferguson, D.O.3    Lee, C.4    Manis, J.5    Fleming, J.6    Gao, Y.7    Morton, C.C.8    Alt, F.W.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.