-
1
-
-
78651514974
-
Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila
-
Bantignies F., Roure V., Comet I., Leblanc B., Schuettengruber B., Bonnet J., Tixier V., Mas A., Cavalli G. Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila. Cell 2011, 144:214-226.
-
(2011)
Cell
, vol.144
, pp. 214-226
-
-
Bantignies, F.1
Roure, V.2
Comet, I.3
Leblanc, B.4
Schuettengruber, B.5
Bonnet, J.6
Tixier, V.7
Mas, A.8
Cavalli, G.9
-
2
-
-
79551681406
-
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
-
Basu U., Meng F.L., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman C.R., Wesemann D.R., et al. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 2011, 144:353-363.
-
(2011)
Cell
, vol.144
, pp. 353-363
-
-
Basu, U.1
Meng, F.L.2
Keim, C.3
Grinstein, V.4
Pefanis, E.5
Eccleston, J.6
Zhang, T.7
Myers, D.8
Wasserman, C.R.9
Wesemann, D.R.10
-
3
-
-
77953916879
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society, Series B 1995, 57:125-133.
-
(1995)
Journal of the Royal Statistical Society, Series B
, vol.57
, pp. 125-133
-
-
Benjamini, Y.1
Hochberg, Y.2
-
4
-
-
54949147307
-
F-Seq: a feature density estimator for high-throughput sequence tags
-
Boyle A.P., Guinney J., Crawford G.E., Furey T.S. F-Seq: a feature density estimator for high-throughput sequence tags. Bioinformatics 2008, 24:2537-2538.
-
(2008)
Bioinformatics
, vol.24
, pp. 2537-2538
-
-
Boyle, A.P.1
Guinney, J.2
Crawford, G.E.3
Furey, T.S.4
-
5
-
-
36949002285
-
Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly
-
Callén E., Nussenzweig M.C., Nussenzweig A. Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly. Oncogene 2007, 26:7759-7764.
-
(2007)
Oncogene
, vol.26
, pp. 7759-7764
-
-
Callén, E.1
Nussenzweig, M.C.2
Nussenzweig, A.3
-
6
-
-
80053558376
-
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
-
Chiarle R., Zhang Y., Frock R.L., Lewis S.M., Molinie B., Ho Y.J., Myers D.R., Choi V.W., Compagno M., Malkin D.J., et al. Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell 2011, 147:107-119.
-
(2011)
Cell
, vol.147
, pp. 107-119
-
-
Chiarle, R.1
Zhang, Y.2
Frock, R.L.3
Lewis, S.M.4
Molinie, B.5
Ho, Y.J.6
Myers, D.R.7
Choi, V.W.8
Compagno, M.9
Malkin, D.J.10
-
7
-
-
70350464349
-
A coming-of-age story: activation-induced cytidine deaminase turns 10
-
Delker R.K., Fugmann S.D., Papavasiliou F.N. A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat. Immunol. 2009, 10:1147-1153.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1147-1153
-
-
Delker, R.K.1
Fugmann, S.D.2
Papavasiliou, F.N.3
-
8
-
-
0002386913
-
On the interpretation of χ2 from contingency tables, and the calculation of P
-
Fisher R.A. On the interpretation of χ2 from contingency tables, and the calculation of P. Journal of the Royal Statistical Society 1922, 85:87-94.
-
(1922)
Journal of the Royal Statistical Society
, vol.85
, pp. 87-94
-
-
Fisher, R.A.1
-
9
-
-
79953032797
-
Mechanisms that promote and suppress chromosomal translocations in lymphocytes
-
Gostissa M., Alt F.W., Chiarle R. Mechanisms that promote and suppress chromosomal translocations in lymphocytes. Annu. Rev. Immunol. 2011, 29:319-350.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 319-350
-
-
Gostissa, M.1
Alt, F.W.2
Chiarle, R.3
-
10
-
-
84859474968
-
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes
-
Hakim O., Resch W., Yamane A., Klein I., Kieffer-Kwon K.R., Jankovic M., Oliveira T., Bothmer A., Voss T.C., Ansarah-Sobrinho C., et al. DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes. Nature 2012, 484:69-74.
-
(2012)
Nature
, vol.484
, pp. 69-74
-
-
Hakim, O.1
Resch, W.2
Yamane, A.3
Klein, I.4
Kieffer-Kwon, K.R.5
Jankovic, M.6
Oliveira, T.7
Bothmer, A.8
Voss, T.C.9
Ansarah-Sobrinho, C.10
-
11
-
-
79959699992
-
CTCF-mediated functional chromatin interactome in pluripotent cells
-
Handoko L., Xu H., Li G., Ngan C.Y., Chew E., Schnapp M., Lee C.W., Ye C., Ping J.L., Mulawadi F., et al. CTCF-mediated functional chromatin interactome in pluripotent cells. Nat. Genet. 2011, 43:630-638.
-
(2011)
Nat. Genet.
, vol.43
, pp. 630-638
-
-
Handoko, L.1
Xu, H.2
Li, G.3
Ngan, C.Y.4
Chew, E.5
Schnapp, M.6
Lee, C.W.7
Ye, C.8
Ping, J.L.9
Mulawadi, F.10
-
12
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I., Zhao Y., Richardson C.J., Green S.J., Martin N.M., Orr A.I., Reaper P.M., Jackson S.P., Curtin N.J., Smith G.C. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 2004, 64:9152-9159.
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
13
-
-
80053502216
-
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes
-
Klein I.A., Resch W., Jankovic M., Oliveira T., Yamane A., Nakahashi H., Di Virgilio M., Bothmer A., Nussenzweig A., Robbiani D.F., et al. Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes. Cell 2011, 147:95-106.
-
(2011)
Cell
, vol.147
, pp. 95-106
-
-
Klein, I.A.1
Resch, W.2
Jankovic, M.3
Oliveira, T.4
Yamane, A.5
Nakahashi, H.6
Di Virgilio, M.7
Bothmer, A.8
Nussenzweig, A.9
Robbiani, D.F.10
-
14
-
-
69649109364
-
Circos: an information aesthetic for comparative genomics
-
Krzywinski M., Schein J., Birol I., Connors J., Gascoyne R., Horsman D., Jones S.J., Marra M.A. Circos: an information aesthetic for comparative genomics. Genome Res. 2009, 19:1639-1645.
-
(2009)
Genome Res.
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.1
Schein, J.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
Jones, S.J.7
Marra, M.A.8
-
15
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
Küppers R. Mechanisms of B-cell lymphoma pathogenesis. Nat. Rev. Cancer 2005, 5:251-262.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 251-262
-
-
Küppers, R.1
-
16
-
-
70349873824
-
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
-
Lieberman-Aiden E., van Berkum N.L., Williams L., Imakaev M., Ragoczy T., Telling A., Amit I., Lajoie B.R., Sabo P.J., Dorschner M.O., et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009, 326:289-293.
-
(2009)
Science
, vol.326
, pp. 289-293
-
-
Lieberman-Aiden, E.1
van Berkum, N.L.2
Williams, L.3
Imakaev, M.4
Ragoczy, T.5
Telling, A.6
Amit, I.7
Lajoie, B.R.8
Sabo, P.J.9
Dorschner, M.O.10
-
17
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
Liu M., Duke J.L., Richter D.J., Vinuesa C.G., Goodnow C.C., Kleinstein S.H., Schatz D.G. Two levels of protection for the B cell genome during somatic hypermutation. Nature 2008, 451:841-845.
-
(2008)
Nature
, vol.451
, pp. 841-845
-
-
Liu, M.1
Duke, J.L.2
Richter, D.J.3
Vinuesa, C.G.4
Goodnow, C.C.5
Kleinstein, S.H.6
Schatz, D.G.7
-
18
-
-
0033603340
-
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
-
Muramatsu M., Sankaranand V.S., Anant S., Sugai M., Kinoshita K., Davidson N.O., Honjo T. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 1999, 274:18470-18476.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18470-18476
-
-
Muramatsu, M.1
Sankaranand, V.S.2
Anant, S.3
Sugai, M.4
Kinoshita, K.5
Davidson, N.O.6
Honjo, T.7
-
19
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000, 102:553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
20
-
-
78751608734
-
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA
-
Nowak U., Matthews A.J., Zheng S., Chaudhuri J. The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA. Nat. Immunol. 2011, 12:160-166.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 160-166
-
-
Nowak, U.1
Matthews, A.J.2
Zheng, S.3
Chaudhuri, J.4
-
21
-
-
77950955761
-
Origin of chromosomal translocations in lymphoid cancer
-
Nussenzweig A., Nussenzweig M.C. Origin of chromosomal translocations in lymphoid cancer. Cell 2010, 141:27-38.
-
(2010)
Cell
, vol.141
, pp. 27-38
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
22
-
-
5444243359
-
Active genes dynamically colocalize to shared sites of ongoing transcription
-
Osborne C.S., Chakalova L., Brown K.E., Carter D., Horton A., Debrand E., Goyenechea B., Mitchell J.A., Lopes S., Reik W., Fraser P. Active genes dynamically colocalize to shared sites of ongoing transcription. Nat. Genet. 2004, 36:1065-1071.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1065-1071
-
-
Osborne, C.S.1
Chakalova, L.2
Brown, K.E.3
Carter, D.4
Horton, A.5
Debrand, E.6
Goyenechea, B.7
Mitchell, J.A.8
Lopes, S.9
Reik, W.10
Fraser, P.11
-
23
-
-
34548210885
-
Myc dynamically and preferentially relocates to a transcription factory occupied by Igh
-
Osborne C.S., Chakalova L., Mitchell J.A., Horton A., Wood A.L., Bolland D.J., Corcoran A.E., Fraser P. Myc dynamically and preferentially relocates to a transcription factory occupied by Igh. PLoS Biol. 2007, 5:e192.
-
(2007)
PLoS Biol.
, vol.5
-
-
Osborne, C.S.1
Chakalova, L.2
Mitchell, J.A.3
Horton, A.4
Wood, A.L.5
Bolland, D.J.6
Corcoran, A.E.7
Fraser, P.8
-
24
-
-
79960220935
-
AID targeting in antibody diversity
-
Pavri R., Nussenzweig M.C. AID targeting in antibody diversity. Adv. Immunol. 2011, 110:1-26.
-
(2011)
Adv. Immunol.
, vol.110
, pp. 1-26
-
-
Pavri, R.1
Nussenzweig, M.C.2
-
25
-
-
77957239251
-
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
-
Pavri R., Gazumyan A., Jankovic M., Di Virgilio M., Klein I., Ansarah-Sobrinho C., Resch W., Yamane A., Reina San-Martin B., Barreto V., et al. Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell 2010, 143:122-133.
-
(2010)
Cell
, vol.143
, pp. 122-133
-
-
Pavri, R.1
Gazumyan, A.2
Jankovic, M.3
Di Virgilio, M.4
Klein, I.5
Ansarah-Sobrinho, C.6
Resch, W.7
Yamane, A.8
Reina San-Martin, B.9
Barreto, V.10
-
26
-
-
42649124572
-
The biochemistry of somatic hypermutation
-
Peled J.U., Kuang F.L., Iglesias-Ussel M.D., Roa S., Kalis S.L., Goodman M.F., Scharff M.D. The biochemistry of somatic hypermutation. Annu. Rev. Immunol. 2008, 26:481-511.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 481-511
-
-
Peled, J.U.1
Kuang, F.L.2
Iglesias-Ussel, M.D.3
Roa, S.4
Kalis, S.L.5
Goodman, M.F.6
Scharff, M.D.7
-
27
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt S.K., Harris R.S., Neuberger M.S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 2002, 418:99-103.
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
28
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada C., Williams G.T., Nilsen H., Barnes D.E., Lindahl T., Neuberger M.S. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 2002, 12:1748-1755.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
29
-
-
73349090560
-
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
-
Schoenfelder S., Sexton T., Chakalova L., Cope N.F., Horton A., Andrews S., Kurukuti S., Mitchell J.A., Umlauf D., Dimitrova D.S., et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat. Genet. 2010, 42:53-61.
-
(2010)
Nat. Genet.
, vol.42
, pp. 53-61
-
-
Schoenfelder, S.1
Sexton, T.2
Chakalova, L.3
Cope, N.F.4
Horton, A.5
Andrews, S.6
Kurukuti, S.7
Mitchell, J.A.8
Umlauf, D.9
Dimitrova, D.S.10
-
30
-
-
23944431983
-
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
-
Schrader C.E., Linehan E.K., Mochegova S.N., Woodland R.T., Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J. Exp. Med. 2005, 202:561-568.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 561-568
-
-
Schrader, C.E.1
Linehan, E.K.2
Mochegova, S.N.3
Woodland, R.T.4
Stavnezer, J.5
-
31
-
-
84856747483
-
Three-dimensional folding and functional organization principles of the Drosophila genome
-
Sexton T., Yaffe E., Kenigsberg E., Bantignies F., Leblanc B., Hoichman M., Parrinello H., Tanay A., Cavalli G. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 2012, 148:458-472.
-
(2012)
Cell
, vol.148
, pp. 458-472
-
-
Sexton, T.1
Yaffe, E.2
Kenigsberg, E.3
Bantignies, F.4
Leblanc, B.5
Hoichman, M.6
Parrinello, H.7
Tanay, A.8
Cavalli, G.9
-
32
-
-
33750212321
-
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
-
Simonis M., Klous P., Splinter E., Moshkin Y., Willemsen R., de Wit E., van Steensel B., de Laat W. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat. Genet. 2006, 38:1348-1354.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1348-1354
-
-
Simonis, M.1
Klous, P.2
Splinter, E.3
Moshkin, Y.4
Willemsen, R.5
de Wit, E.6
van Steensel, B.7
de Laat, W.8
-
33
-
-
0035554683
-
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes
-
Skok J.A., Brown K.E., Azuara V., Caparros M.L., Baxter J., Takacs K., Dillon N., Gray D., Perry R.P., Merkenschlager M., Fisher A.G. Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. Nat. Immunol. 2001, 2:848-854.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 848-854
-
-
Skok, J.A.1
Brown, K.E.2
Azuara, V.3
Caparros, M.L.4
Baxter, J.5
Takacs, K.6
Dillon, N.7
Gray, D.8
Perry, R.P.9
Merkenschlager, M.10
Fisher, A.G.11
-
34
-
-
78651468710
-
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells
-
Staszewski O., Baker R.E., Ucher A.J., Martier R., Stavnezer J., Guikema J.E. Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells. Mol. Cell 2011, 41:232-242.
-
(2011)
Mol. Cell
, vol.41
, pp. 232-242
-
-
Staszewski, O.1
Baker, R.E.2
Ucher, A.J.3
Martier, R.4
Stavnezer, J.5
Guikema, J.E.6
-
35
-
-
79955632686
-
Complex regulation and function of activation-induced cytidine deaminase
-
Stavnezer J. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol. 2011, 32:194-201.
-
(2011)
Trends Immunol.
, vol.32
, pp. 194-201
-
-
Stavnezer, J.1
-
37
-
-
79955639340
-
AID and partners: for better and (not) for worse
-
Storck S., Aoufouchi S., Weill J.C., Reynaud C.A. AID and partners: for better and (not) for worse. Curr. Opin. Immunol. 2011, 23:337-344.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 337-344
-
-
Storck, S.1
Aoufouchi, S.2
Weill, J.C.3
Reynaud, C.A.4
-
38
-
-
51049110262
-
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development
-
Takizawa M., Tolarová H., Li Z., Dubois W., Lim S., Callen E., Franco S., Mosaico M., Feigenbaum L., Alt F.W., et al. AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development. J. Exp. Med. 2008, 205:1949-1957.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1949-1957
-
-
Takizawa, M.1
Tolarová, H.2
Li, Z.3
Dubois, W.4
Lim, S.5
Callen, E.6
Franco, S.7
Mosaico, M.8
Feigenbaum, L.9
Alt, F.W.10
-
39
-
-
77956345401
-
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination
-
Xu Z., Fulop Z., Wu G., Pone E.J., Zhang J., Mai T., Thomas L.M., Al-Qahtani A., White C.A., Park S.R., et al. 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat. Struct. Mol. Biol. 2010, 17:1124-1135.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1124-1135
-
-
Xu, Z.1
Fulop, Z.2
Wu, G.3
Pone, E.J.4
Zhang, J.5
Mai, T.6
Thomas, L.M.7
Al-Qahtani, A.8
White, C.A.9
Park, S.R.10
-
40
-
-
78650308767
-
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
-
Yamane A., Resch W., Kuo N., Kuchen S., Li Z., Sun H.W., Robbiani D.F., McBride K., Nussenzweig M.C., Casellas R. Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nat. Immunol. 2011, 12:62-69.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 62-69
-
-
Yamane, A.1
Resch, W.2
Kuo, N.3
Kuchen, S.4
Li, Z.5
Sun, H.W.6
Robbiani, D.F.7
McBride, K.8
Nussenzweig, M.C.9
Casellas, R.10
-
41
-
-
84862778059
-
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations
-
Zhang Y., McCord R.P., Ho Y.J., Lajoie B.R., Hildebrand D.G., Simon A.C., Becker M.S., Alt F.W., Dekker J. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell 2012, 148:908-921.
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(2012)
Cell
, vol.148
, pp. 908-921
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Zhang, Y.1
McCord, R.P.2
Ho, Y.J.3
Lajoie, B.R.4
Hildebrand, D.G.5
Simon, A.C.6
Becker, M.S.7
Alt, F.W.8
Dekker, J.9
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