메뉴 건너뛰기




Volumn 462, Issue 7274, 2009, Pages 803-807

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3′ regulatory region

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE;

EID: 72049100181     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08633     Document Type: Article
Times cited : (71)

References (30)
  • 1
    • 0035839959 scopus 로고    scopus 로고
    • Mechanisms of chromosomal translocations in B cell lymphomas
    • Küppers, R. & Dalla-Favera, R. Mechanisms of chromosomal translocations in B cell lymphomas. Oncogene 20, 5580-5594 (2001).
    • (2001) Oncogene , vol.20 , pp. 5580-5594
    • Küppers, R.1    Dalla-Favera, R.2
  • 2
    • 33748138991 scopus 로고    scopus 로고
    • Roles of nonhomologous DNA end joining, V(D) J recombination, and class switch recombination in chromosomal translocations
    • Lieber, M. R., Yu, K. & Raghavan, S. C. Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations. DNA Repair (Amst.) 5, 1234-1245 (2006).
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 1234-1245
    • Lieber, M.R.1    Yu, K.2    Raghavan, S.C.3
  • 3
    • 34249793250 scopus 로고    scopus 로고
    • The role of activation-induced deaminase in antibody diversification and chromosome translocations
    • Ramiro, A. et al. The role of activation-induced deaminase in antibody diversification and chromosome translocations. Adv. Immunol. 94, 75-107 (2007).
    • (2007) Adv. Immunol. , vol.94 , pp. 75-107
    • Ramiro, A.1
  • 4
    • 57149146036 scopus 로고    scopus 로고
    • AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
    • Robbiani, D. F. et al. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 135, 1028-1038 (2008).
    • (2008) Cell , vol.135 , pp. 1028-1038
    • Robbiani, D.F.1
  • 5
    • 0036240127 scopus 로고    scopus 로고
    • The mechanism and regulation of chromosomal V(D) J recombination
    • Bassing, C. H., Swat, W. & Alt, F. W. The mechanism and regulation of chromosomal V(D)J recombination. Cell 109 (suppl.), S45-S55 (2002).
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Bassing, C.H.1    Swat, W.2    Alt, F.W.3
  • 6
    • 34249794280 scopus 로고    scopus 로고
    • Evolution of the immunoglobulin heavy chain class switch recombination mechanism
    • Chaudhuri, J. et al. Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Adv. Immunol. 94, 157-214 (2007).
    • (2007) Adv. Immunol. , vol.94 , pp. 157-214
    • Chaudhuri, J.1
  • 7
    • 0031942986 scopus 로고    scopus 로고
    • Transcriptional regulation during B cell development
    • Henderson, A. & Calame, K. Transcriptional regulation during B cell development. Annu. Rev. Immunol. 16, 163-200 (1998).
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 163-200
    • Henderson, A.1    Calame, K.2
  • 8
    • 0028233142 scopus 로고
    • A class switch control region at the 39 end of the immunoglobulin heavy chain locus
    • Cogné, M. et al. A class switch control region at the 39 end of the immunoglobulin heavy chain locus. Cell 77, 737-747 (1994).
    • (1994) Cell , vol.77 , pp. 737-747
    • Cogné, M.1
  • 9
    • 0033918521 scopus 로고    scopus 로고
    • The 39 IgH regulatory region: A complex structure in a search for a function
    • Khamlichi, A. A., Pinaud, E., Decourt, C., Chauveau, C. & Cogne, M. The 39 IgH regulatory region: a complex structure in a search for a function. Adv. Immunol. 75, 317-345 (2000).
    • (2000) Adv. Immunol. , vol.75 , pp. 317-345
    • Khamlichi, A.A.1    Pinaud, E.2    Decourt, C.3    Chauveau, C.4    Cogne, M.5
  • 10
    • 0034741932 scopus 로고    scopus 로고
    • Localization of the 39 IgH locus elements that effect long-distance regulation of class switch recombination
    • Pinaud, E. et al. Localization of the 39 IgH locus elements that effect long-distance regulation of class switch recombination. Immunity 15, 187-199 (2001).
    • (2001) Immunity , vol.15 , pp. 187-199
    • Pinaud, E.1
  • 11
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • Adams, J. M. et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 318, 533-538 (1985).
    • (1985) Nature , vol.318 , pp. 533-538
    • Adams, J.M.1
  • 12
    • 33747893961 scopus 로고    scopus 로고
    • Myc translocations in B cell and plasma cell neoplasms
    • Janz, S. Myc translocations in B cell and plasma cell neoplasms. DNA Repair (Amst.) 5, 1213-1224 (2006).
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 1213-1224
    • Janz, S.1
  • 13
    • 0343567080 scopus 로고
    • Transgenic mice bearing the human c-myc gene activated by an immunoglobulin enhancer: A pre-B-cell lymphoma model
    • Schmidt, E. V., Pattengale, P. K., Weir, L. & Leder, P. Transgenic mice bearing the human c-myc gene activated by an immunoglobulin enhancer: a pre-B-cell lymphoma model. Proc. Natl Acad. Sci. USA 85, 6047-6051 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 6047-6051
    • Schmidt, E.V.1    Pattengale, P.K.2    Weir, L.3    Leder, P.4
  • 14
    • 38449097468 scopus 로고    scopus 로고
    • The 39IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype
    • Truffinet, V. et al. The 39IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype. J. Immunol. 179, 6033-6042 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 6033-6042
    • Truffinet, V.1
  • 15
    • 16844385104 scopus 로고    scopus 로고
    • Regulatory elements in the immunoglobulin heavy chain gene 39-enhancers induce c-myc deregulation and lymphomagenesis in murine B cells
    • Wang, J. & Boxer, L. M. Regulatory elements in the immunoglobulin heavy chain gene 39-enhancers induce c-myc deregulation and lymphomagenesis in murine B cells. J. Biol. Chem. 280, 12766-12773 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 12766-12773
    • Wang, J.1    Boxer, L.M.2
  • 16
    • 34548784305 scopus 로고    scopus 로고
    • In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 39 regulatory region induces MYC expression at the immature stage of B cell development
    • Yan, Y., Park, S. S., Janz, S. & Eckhardt, L. A. In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 39 regulatory region induces MYC expression at the immature stage of B cell development. Genes Chromosom. Cancer 46, 950-959 (2007).
    • (2007) Genes Chromosom. Cancer , vol.46 , pp. 950-959
    • Yan, Y.1    Park, S.S.2    Janz, S.3    Eckhardt, L.A.4
  • 17
    • 0036152242 scopus 로고    scopus 로고
    • Mechanism and control of class-switch recombination
    • Manis, J. P., Tian, M. & Alt, F. W. Mechanism and control of class-switch recombination. Trends Immunol. 23, 31-39 (2002).
    • (2002) Trends Immunol , vol.23 , pp. 31-39
    • Manis, J.P.1    Tian, M.2    Alt, F.W.3
  • 18
    • 0027969316 scopus 로고
    • Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells
    • Madisen, L. & Groudine, M. Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells. Genes Dev. 8, 2212-2226 (1994).
    • (1994) Genes Dev , vol.8 , pp. 2212-2226
    • Madisen, L.1    Groudine, M.2
  • 21
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • Lieber, M. R. The mechanism of human nonhomologous DNA end joining. J. Biol. Chem. 283, 1-5 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 22
    • 0037188898 scopus 로고    scopus 로고
    • Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
    • Zhu, C. et al. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 109, 811-821 (2002).
    • (2002) Cell , vol.109 , pp. 811-821
    • Zhu, C.1
  • 23
    • 0037136318 scopus 로고    scopus 로고
    • Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification
    • Difilippantonio, M. J. et al. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J. Exp. Med. 196, 469-480 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 469-480
    • Difilippantonio, M.J.1
  • 24
    • 34748863465 scopus 로고    scopus 로고
    • IgH class switching and translocations use a robust non-classical end-joining pathway
    • Yan, C. T. et al. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449, 478-482 (2007).
    • (2007) Nature , vol.449 , pp. 478-482
    • Yan, C.T.1
  • 25
    • 59649086891 scopus 로고    scopus 로고
    • Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching
    • Wang, J. H. et al. Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching. J. Exp. Med. 205, 3079-3090 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 3079-3090
    • Wang, J.H.1
  • 26
    • 67650457059 scopus 로고    scopus 로고
    • Mechanisms promoting translocations in editing and switching peripheral B cells
    • Wang, J. H. et al. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature 460, 231-236 (2009).
    • (2009) Nature , vol.460 , pp. 231-236
    • Wang, J.H.1
  • 27
    • 30744445418 scopus 로고    scopus 로고
    • H2AX prevents DNA breaks from progressing to chromosome breaks and translocations
    • Franco, S. et al. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol. Cell 21, 201-214 (2006).
    • (2006) Mol. Cell , vol.21 , pp. 201-214
    • Franco, S.1
  • 28
    • 33644643189 scopus 로고    scopus 로고
    • Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
    • Ramiro, A. R. et al. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature 440, 105-109 (2006).
    • (2006) Nature , vol.440 , pp. 105-109
    • Ramiro, A.R.1
  • 29
    • 0023988146 scopus 로고
    • Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma
    • Neri, A., Barriga, F., Knowles, D. M., Magrath, I. T. & Dalla-Favera, R. Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma. Proc. Natl Acad. Sci. USA 85, 2748-2752 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 2748-2752
    • Neri, A.1    Barriga, F.2    Knowles, D.M.3    Magrath, I.T.4    Dalla-Favera, R.5
  • 30
    • 0033634973 scopus 로고    scopus 로고
    • DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
    • Frank, K. M. et al. DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol. Cell 5, 993-1002 (2000).
    • (2000) Mol. Cell , vol.5 , pp. 993-1002
    • Frank, K.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.