Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

Nature

Volumn 424, Issue 6944, 2003, Pages 103-107

  Pham, Phuong ^a   Bransteitter, Ronda ^a   Petruska, John ^a   Goodman, Myron F ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CELLS; CLONING; DNA; MUTAGENESIS; RNA;

DEAMINATION;

PROTEINS;

ARGININE; CYTIDINE DEAMINASE; CYTOSINE DERIVATIVE; DOUBLE STRANDED DNA; LYSINE; RNA POLYMERASE; SINGLE STRANDED DNA;

DNA; MUTATION; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DEAMINATION; DNA RNA HYBRIDIZATION; DNA SEQUENCE; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; SOMATIC HYPERMUTATION;

AMINATION; BASE SEQUENCE; CYTIDINE DEAMINASE; DNA, SINGLE-STRANDED; MOLECULAR SEQUENCE DATA; MUTATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSCRIPTION, GENETIC;

ESCHERICHIA COLI;

EID: 0037926476     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01760     Document Type: Article

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