Immunoglobulin class switch recombination is impaired in Atm-deficient mice

Journal of Experimental Medicine

Volumn 200, Issue 9, 2004, Pages 1111-1121

  Lumsden, Joanne M ^a   McCarty, Thomas ^b   Petiniot, Lisa K ^a,c   Shen, Rhuna ^a,c   Barlow, Carrolee ^d,f   Wynn, Thomas A ^b   Morse III, Herbert C ^b   Gearhart, Patricia J ^e   Wynshaw Boris, Anthony ^d,g   Max, Edward E ^c   Hodes, Richard J ^a,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f MERCK RESEARCH LABORATORIES   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ataxia telangiectasia; B lymphocytes; DNA damage; DNA repair; Ig class switching

Indexed keywords

ATM PROTEIN; CD40 LIGAND; CYTOKINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D ANTIBODY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; LIPOPOLYSACCHARIDE; PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC RECOMBINATION; IMMUNOGLOBULIN GENE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; CELL CYCLE PROTEINS; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCEINS; HEMOCYANIN; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN SWITCH REGION; IMMUNOGLOBULINS; MICE; MICE, MUTANT STRAINS; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; SUCCINIMIDES; TUMOR SUPPRESSOR PROTEINS;

EID: 8644242383     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041074     Document Type: Article

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