ATM is required for efficient recombination between immunoglobulin switch regions

Journal of Experimental Medicine

Volumn 200, Issue 9, 2004, Pages 1103-1110

  Reina San Martin, Bernardo ^a   Chen, Hua Tang ^b   Nussenzweig, André ^b   Nussenzweig, Michel C ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Activation induced cytidine deaminase; ATM; Class switch recombination; DNA repair; Somatic hypermutation

Indexed keywords

ATM PROTEIN;

ANIMAL CELL; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; CELL CYCLE; CHROMOSOME PAIRING; CONTROLLED STUDY; DNA STRAND BREAKAGE; GENETIC RECOMBINATION; GENETIC VARIABILITY; IMMUNE DEFICIENCY; IMMUNOGLOBULIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOMATIC MUTATION;

ANIMALS; B-LYMPHOCYTES; BLOTTING, SOUTHERN; CELL CYCLE PROTEINS; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, INBRED STRAINS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 8644238314     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041162     Document Type: Article

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