RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

Cell

Volumn 117, Issue 2, 2004, Pages 171-184

  Lee, Gregory S ^a   Neiditch, Matthew B ^b   Salus, Sandra S ^a   Roth, David B ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; RAG1 PROTEIN; RAG2 PROTEIN;

ANIMAL CELL; ARTICLE; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ERROR; EVOLUTION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; MOLECULAR MECHANICS; MOLECULE; MUTATION; NONHOMOLOGOUS END JOINING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STABILITY; STIMULATION;

ANIMALIA;

EID: 1942421722     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00301-0     Document Type: Article

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