DNA Polymerase η Is Involved in Hypermutation Occurring during Immunoglobulin Class Switch Recombination

Journal of Experimental Medicine

Volumn 199, Issue 2, 2004, Pages 265-270

  Faili, Ahmad ^a   Aoufouchi, Said ^a   Weller, Sandra ^a   Vuillier, Françoise ^b   Stary, Anne ^c   Sarasin, Alain ^c   Reynaud, Claude Agnès ^a   Weill, Jean Claude ^a  

^a INSERM   (France)

^b INSTITUT PASTEUR   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Pol ; Somatic mutation; Translesional DNA polymerases; Xeroderma pigmentosum variant syndrome

Indexed keywords

ADENINE; CYTIDINE DEAMINASE; DNA DIRECTED DNA POLYMERASE ETA; DNA POLYMERASE; IMMUNOGLOBULIN; THYMINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; B LYMPHOCYTE; CASE REPORT; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME DEFICIENCY; GENE DELETION; GENE DUPLICATION; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; MEMORY CELL; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION; TANDEM REPEAT; XERODERMA PIGMENTOSUM;

ADULT; B-LYMPHOCYTES; BASE SEQUENCE; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; DNA; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; FEMALE; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOLOGIC MEMORY; INTRONS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; RECOMBINATION, GENETIC; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; XERODERMA PIGMENTOSUM;

EID: 1642499721     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20031831     Document Type: Article

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