AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 52, 2009, Pages 22375-22380

  Kobayashi, Maki ^a   Aida, Masatoshi ^a   Nagaoka, Hitoshi ^a   Begum, Nasim A ^a   Kitawaki, Yoko ^a   Nakata, Mikiyo ^a   Stanlie, Andre ^a   Doi, Tomomitsu ^a   Kato, Lucia ^a   Okazaki, Il Mi ^a,b   Shinkura, Reiko ^a   Muramatsu, Masamichi ^a,c   Kinoshita, Kazuo ^a,d   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d Shiga Medical Center   (Japan)

Author keywords

Camptothecin; Non B DNA; Translation suppression

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CAMPTOTHECIN; COMPLEMENTARY DNA; DNA TOPOISOMERASE; MESSENGER RNA;

ARTICLE; DNA CLEAVAGE; DNA SEQUENCE; DNA STRUCTURE; ENZYME DEGRADATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSLATION REGULATION; WILD TYPE;

ANIMALS; B-LYMPHOCYTES; CAMPTOTHECIN; CELL LINE; CYTIDINE DEAMINASE; DNA; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; IMMUNOGLOBULIN CLASS SWITCHING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEIC ACID CONFORMATION; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 76049125030     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911879106     Document Type: Article

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