Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID

Journal of Experimental Medicine

Volumn 207, Issue 1, 2010, Pages 141-153

  Wang, Meng ^a   Rada, Cristina ^a   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; APOBEC3C PROTEIN; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3F; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; DEOXYCYTIDINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN V; NUCLEOTIDE; PURINE; PYRIMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CATALYSIS; CHICKEN; CONTROLLED STUDY; DEAMINATION; DNA SEQUENCE; ENZYME SPECIFICITY; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC HYPERMUTATION;

5' FLANKING REGION; ANIMALS; ANTIBODY AFFINITY; CELL LINE; CYTIDINE DEAMINASE; DEAMINATION; DNA; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, KNOCKOUT; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; SUBSTRATE SPECIFICITY;

EID: 76149119416     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20092238     Document Type: Article

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