Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to Sμ in Ig class switch recombination

International Immunology

Volumn 16, Issue 4, 2004, Pages 549-557

  Rush, James S ^a   Fugmann, Sebastian D ^a   Schatz, David G ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Activation induced cytidine deaminase; B lymphocyte; Class switch recombination; DNA double strand break

Indexed keywords

CYTIDINE DEAMINASE; DOUBLE STRANDED DNA; IMMUNOGLOBULIN CLASS;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; GENE REARRANGEMENT; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; BLOTTING, SOUTHERN; CELL DIVISION; CYTIDINE DEAMINASE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; DNA DAMAGE; DNA PRIMERS; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN SWITCH REGION; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLASMIDS; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC;

EID: 1842865725     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh057     Document Type: Article

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