DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

Nature

Volumn 484, Issue 7392, 2012, Pages 69-74

  Hakim, Ofir ^a   Resch, Wolfgang ^b   Yamane, Arito ^b   Klein, Isaac ^c   Kieffer Kwon, Kyong Rim ^b   Jankovic, Mila ^c   Oliveira, Thiago ^c,d   Bothmer, Anne ^c   Voss, Ty C ^a   Ansarah Sobrinho, Camilo ^b   Mathe, Ewy ^b   Liang, Genqing ^b   Cobell, Jesse ^b   Nakahashi, Hirotaka ^b   Robbiani, Davide F ^c   Nussenzweig, Andre ^a   Hager, Gordon L ^a   Nussenzweig, Michel C ^c   Casellas, Rafael ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

REPLICATION FACTOR A;

CELL ORGANELLE; CHROMOSOME; DNA; FREQUENCY ANALYSIS; HEMATOLOGY; RODENT; TRANSLOCATION; TUMOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BIOACCUMULATION; CHROMOSOME TRANSLOCATION; DNA DAMAGE; DNA STRAND BREAKAGE; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC SYSTEM; IMMUNOGLOBULIN HEAVY CHAIN GENE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; SOLID TUMOR;

ANIMALS; B-LYMPHOCYTES; CELL NUCLEUS; CELLS, CULTURED; CHROMOSOME POSITIONING; CHROMOSOMES, MAMMALIAN; CYTIDINE DEAMINASE; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; GENES, MYC; GENOME; IMMUNOGLOBULIN HEAVY CHAINS; MICE; REPLICATION PROTEIN A; TRANSLOCATION, GENETIC;

EID: 84859474968     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10909     Document Type: Article

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