Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: Parallels with somatic hypermutation

EMBO Journal

Volumn 18, Issue 12, 1999, Pages 3484-3490

  Ehrenstein, Michael R ^a   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Heavy chain switch recombination; Immunoglobulin class switching; Mismatch repair; Msh2; Somatic hypermutation

Indexed keywords

CELL PROTEIN; DNA DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CONTROLLED STUDY; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC RECOMBINATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, T-INDEPENDENT; B-LYMPHOCYTES; BASE PAIR MISMATCH; BASE SEQUENCE; CELLS, CULTURED; DNA REPAIR; DNA-BINDING PROTEINS; FICOLL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; MUTS HOMOLOG 2 PROTEIN; PEYER'S PATCHES; PROTO-ONCOGENE PROTEINS; RECOMBINATION, GENETIC;

EID: 0033564878     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.12.3484     Document Type: Article

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