Molecular mechanism of class switch recombination: Linkage with somatic hypermutation

Annual Review of Immunology

Volumn 20, Issue , 2002, Pages 165-196

  Honjo, Tasuku ^a   Kinoshita, Kazuo ^a   Muramatsu, Masamichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

AID; Nick endonuclease; RNA editing; Stem loop structure; Transcription

Indexed keywords

CYTIDINE DEAMINASE; CYTOKINE; DNA POLYMERASE; DNA TOPOISOMERASE; ENDONUCLEASE; EXONUCLEASE; MESSENGER RNA;

CLASS SWITCH RECOMBINATION; CORRELATION ANALYSIS; DNA CLEAVAGE; DNA MODIFICATION; ENZYME ACTIVITY; GENE MUTATION; GENE TARGETING; GENETIC RECOMBINATION; HUMAN; LINKAGE ANALYSIS; MISMATCH REPAIR; NICK END LABELING; PRIORITY JOURNAL; REACTION ANALYSIS; REVIEW; RNA EDITING; SOMATIC HYPERMUTATION; SOMATIC MUTATION; TRANSCRIPTION REGULATION;

ANIMALS; BASE PAIR MISMATCH; CYTIDINE DEAMINASE; DNA NUCLEOTIDYLTRANSFERASES; DNA REPAIR; GENES, SWITCH; HUMANS; LINKAGE (GENETICS); MODELS, GENETIC; MUTATION; RECOMBINASES; RECOMBINATION, GENETIC; RNA EDITING;

EID: 0036212917     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.20.090501.112049     Document Type: Review

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253. Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex
254. Towards an understanding of somatic hypermutation
255. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
256. Cell cycle regulation of immunoglobulin class switch recombination and germline transcription: Potential role of Ets family members