-
1
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R. Origin and physiological roles of inflammation. Nature (2008) 454:428-35. doi:10.1038/nature07201
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
2
-
-
77950345093
-
Inflammation 2010, new adventures of an old flame
-
Medzhitov R. Inflammation 2010: new adventures of an old flame. Cell (2010) 140:771-6. doi:10.1016/j.cell.2010.03.006
-
(2010)
Cell
, vol.140
, pp. 771-776
-
-
Medzhitov, R.1
-
3
-
-
84866512376
-
Cell volume regulation modulates NLRP3 inflammasome activation
-
Compan V, Baroja-Mazo A, López-Castejón G, Gomez AI, Martínez CM, Angosto D, et al. Cell volume regulation modulates NLRP3 inflammasome activation. Immunity (2012) 37:487-500. doi:10.1016/j.immuni.2012.06.013
-
(2012)
Immunity
, vol.37
, pp. 487-500
-
-
Compan, V.1
Baroja-Mazo, A.2
López-Castejón, G.3
Gomez, A.I.4
Martínez, C.M.5
Angosto, D.6
-
4
-
-
84929145248
-
Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation
-
Ip WKE, Medzhitov R. Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation. Nat Commun (2015) 6:6931. doi:10.1038/ncomms7931
-
(2015)
Nat Commun
, vol.6
, pp. 6931
-
-
Ip, W.K.E.1
Medzhitov, R.2
-
5
-
-
84863216838
-
Inflammasome activation by danger signals
-
Couillin I, Petrilli V, Martinon F, editors. Basel: Springer
-
Pelegrin P. Inflammasome activation by danger signals. In: Couillin I, Petrilli V, Martinon F, editors. The Inflammasomes. Basel: Springer (2011). p. 101-21.
-
(2011)
The Inflammasomes
, pp. 101-121
-
-
Pelegrin, P.1
-
6
-
-
84921909014
-
The inflammasomes and autoinflammatory syndromes
-
Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E. The inflammasomes and autoinflammatory syndromes. Annu Rev Pathol (2015) 10:395-424. doi:10.1146/annurev-pathol-012414-040431
-
(2015)
Annu Rev Pathol
, vol.10
, pp. 395-424
-
-
Broderick, L.1
De Nardo, D.2
Franklin, B.S.3
Hoffman, H.M.4
Latz, E.5
-
7
-
-
29944438881
-
Necrotic death as a cell fate
-
Zong WX, Thompson CB. Necrotic death as a cell fate. Genes Dev (2006) 20:1-15. doi:10.1101/gad.1376506
-
(2006)
Genes Dev
, vol.20
, pp. 1-15
-
-
Zong, W.X.1
Thompson, C.B.2
-
8
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M, Dixit VM. Mechanisms and functions of inflammasomes. Cell (2014) 157:1013-22. doi:10.1016/j.cell.2014.04.007
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
9
-
-
84900530332
-
Nucleotide signalling during inflammation
-
Idzko M, Ferrari D, Eltzschig HK. Nucleotide signalling during inflammation. Nature (2014) 509:310-7. doi:10.1038/nature13085
-
(2014)
Nature
, vol.509
, pp. 310-317
-
-
Idzko, M.1
Ferrari, D.2
Eltzschig, H.K.3
-
10
-
-
67649639047
-
Signaling at purinergic P2X receptors
-
Surprenant A, North RA. Signaling at purinergic P2X receptors. Annu Rev Physiol (2009) 71:333-59. doi:10.1146/annurev.physiol.70.113006.100630
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 333-359
-
-
Surprenant, A.1
North, R.A.2
-
11
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, et al. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat Immunol (2014) 15:738-48. doi:10.1038/ni.2919
-
(2014)
Nat Immunol
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martín-Sánchez, F.2
Gomez, A.I.3
Martínez, C.M.4
Amores-Iniesta, J.5
Compan, V.6
-
12
-
-
84862270214
-
P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release
-
Barberà-Cremades M, Baroja-Mazo A, Gomez AI, Machado F, Di Virgilio F, Pelegrin P. P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release. FASEB J (2012) 26:2951-62. doi:10.1096/fj.12-205765
-
(2012)
FASEB J
, vol.26
, pp. 2951-2962
-
-
Barberà-Cremades, M.1
Baroja-Mazo, A.2
Gomez, A.I.3
Machado, F.4
Di Virgilio, F.5
Pelegrin, P.6
-
13
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
Keller M, Rüegg A, Werner S, Beer H-D. Active caspase-1 is a regulator of unconventional protein secretion. Cell (2008) 132:818-31. doi:10.1016/j.cell.2007.12.040
-
(2008)
Cell
, vol.132
, pp. 818-831
-
-
Keller, M.1
Rüegg, A.2
Werner, S.3
Beer, H.-D.4
-
14
-
-
84960155925
-
Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process
-
de Torre-Minguela C, Barberà-Cremades M, Gomez AI, Martin-Sanchez F, Pelegrin P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep (2016) 6:22586. doi:10.1038/srep22586
-
(2016)
Sci Rep
, vol.6
, pp. 22586
-
-
de Torre-Minguela, C.1
Barberà-Cremades, M.2
Gomez, A.I.3
Martin-Sanchez, F.4
Pelegrin, P.5
-
15
-
-
84904692363
-
The adaptor ASC has extracellular and "prionoid" activities that propagate inflammation
-
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, et al. The adaptor ASC has extracellular and "prionoid" activities that propagate inflammation. Nat Immunol (2014) 15:727-37. doi:10.1038/ni.2913
-
(2014)
Nat Immunol
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
-
16
-
-
84863173852
-
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses
-
Yang D, Postnikov YV, Li Y, Tewary P, de la Rosa G, Wei F, et al. High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses. J Exp Med (2012) 209:157-71. doi:10.1084/jem.20101354
-
(2012)
J Exp Med
, vol.209
, pp. 157-171
-
-
Yang, D.1
Postnikov, Y.V.2
Li, Y.3
Tewary, P.4
de la Rosa, G.5
Wei, F.6
-
17
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol (2013) 13:397-411. doi:10.1038/nri3452
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
18
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature (2009) 458:509-13. doi:10.1038/nature07710
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
19
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature (2009) 458:514-8. doi:10.1038/nature07725
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
-
20
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science (2009) 323:1057-60. doi:10.1126/science.1169841
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
-
21
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, et al. IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol (2010) 11:997-1004. doi:10.1038/ni.1932
-
(2010)
Nat Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
-
22
-
-
79956061094
-
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
-
Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, et al. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection. Cell Host Microbe (2011) 9:363-75. doi:10.1016/j.chom.2011.04.008
-
(2011)
Cell Host Microbe
, vol.9
, pp. 363-375
-
-
Kerur, N.1
Veettil, M.V.2
Sharma-Walia, N.3
Bottero, V.4
Sadagopan, S.5
Otageri, P.6
-
23
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol (2010) 11:63-9. doi:10.1038/ni.1824
-
(2010)
Nat Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
-
24
-
-
40449140937
-
The NLR gene family: a standard nomenclature
-
Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, et al. The NLR gene family: a standard nomenclature. Immunity (2008) 28:285-7. doi:10.1016/j.immuni.2008.02.005
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
Lovering, R.C.2
Alnemri, E.S.3
Bertin, J.4
Boss, J.M.5
Davis, B.K.6
-
25
-
-
84891906749
-
Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
-
Zaki MH, Man SM, Vogel P, Lamkanfi M, Kanneganti TD. Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection. Proc Natl Acad Sci U S A (2014) 111:385-90. doi:10.1073/pnas.1317643111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 385-390
-
-
Zaki, M.H.1
Man, S.M.2
Vogel, P.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
26
-
-
84928196080
-
The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells
-
Lukens JR, Lukens JR, Gurung P, Gurung P, Shaw PJ, Shaw PJ, et al. The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells. Immunity (2015) 42:654-64. doi:10.1016/j.immuni.2015.03.006
-
(2015)
Immunity
, vol.42
, pp. 654-664
-
-
Lukens, J.R.1
Lukens, J.R.2
Gurung, P.3
Gurung, P.4
Shaw, P.J.5
Shaw, P.J.6
-
27
-
-
84865130689
-
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
-
Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, et al. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature (2012) 488:389-93. doi:10.1038/nature11250
-
(2012)
Nature
, vol.488
, pp. 389-393
-
-
Anand, P.K.1
Malireddi, R.K.2
Lukens, J.R.3
Vogel, P.4
Bertin, J.5
Lamkanfi, M.6
-
28
-
-
84949255269
-
Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling
-
Levy M, Thaiss CA, Zeevi D, Dohnalova L, Zilberman-Schapira G, Mahdi JA, et al. Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling. Cell (2015) 163:1428-43. doi:10.1016/j.cell.2015.10.048
-
(2015)
Cell
, vol.163
, pp. 1428-1443
-
-
Levy, M.1
Thaiss, C.A.2
Zeevi, D.3
Dohnalova, L.4
Zilberman-Schapira, G.5
Mahdi, J.A.6
-
29
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell (2002) 10:417-26. doi:10.1016/S1097-2765(02)00599-3
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
30
-
-
84861215715
-
Proteolytic processing of Nlrp1b is required for inflammasome activity
-
Frew BC, Joag VR, Mogridge J. Proteolytic processing of Nlrp1b is required for inflammasome activity. PLoS Pathog (2012) 8:e1002659. doi:10.1371/journal.ppat.1002659
-
(2012)
PLoS Pathog
, vol.8
-
-
Frew, B.C.1
Joag, V.R.2
Mogridge, J.3
-
31
-
-
84879508269
-
Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor
-
Chavarria-Smith J, Vance RE. Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor. PLoS Pathog (2013) 9:e1003452. doi:10.1371/journal.ppat.1003452
-
(2013)
PLoS Pathog
, vol.9
-
-
Chavarria-Smith, J.1
Vance, R.E.2
-
32
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, Bailly-Maitre B, et al. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell (2007) 25:713-24. doi:10.1016/j.molcel.2007.01.032
-
(2007)
Mol Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
-
33
-
-
84988622178
-
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation
-
Zhong FL, Mamaï O, Sborgi L, Boussofara L, Hopkins R, Robinson K, et al. Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation. Cell (2016) 167:187-202.e17. doi:10.1016/j.cell.2016.09.001
-
(2016)
Cell
, vol.167
-
-
Zhong, F.L.1
Mamaï, O.2
Sborgi, L.3
Boussofara, L.4
Hopkins, R.5
Robinson, K.6
-
34
-
-
84870950668
-
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells
-
Masters SL, Gerlic M, Metcalf D, Preston S, Pellegrini M, O'Donnell JA, et al. NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. Immunity (2012) 37:1009-23. doi:10.1016/j.immuni.2012.08.027
-
(2012)
Immunity
, vol.37
, pp. 1009-1023
-
-
Masters, S.L.1
Gerlic, M.2
Metcalf, D.3
Preston, S.4
Pellegrini, M.5
O'Donnell, J.A.6
-
35
-
-
33947497237
-
NALP1 in vitiligo-associated multiple autoimmune disease
-
Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, Bennett DC, et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med (2007) 356:1216-25. doi:10.1056/NEJMoa061592
-
(2007)
N Engl J Med
, vol.356
, pp. 1216-1225
-
-
Jin, Y.1
Mailloux, C.M.2
Gowan, K.3
Riccardi, S.L.4
LaBerge, G.5
Bennett, D.C.6
-
36
-
-
85006995122
-
A new autoinflammatory and autoimmune syndrome associated with NLRP1 mutations: NAIAD (NLRP1-associated autoinflammation with arthritis and dyskeratosis)
-
Grandemange S, Sanchez E, Louis-Plence P, Tran Mau-Them F, Bessis D, Coubes C, et al. A new autoinflammatory and autoimmune syndrome associated with NLRP1 mutations: NAIAD (NLRP1-associated autoinflammation with arthritis and dyskeratosis). Ann Rheum Dis (2016). doi:10.1136/annrheumdis-2016-210021
-
(2016)
Ann Rheum Dis
-
-
Grandemange, S.1
Sanchez, E.2
Louis-Plence, P.3
Tran Mau-Them, F.4
Bessis, D.5
Coubes, C.6
-
37
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 29:301-5. doi:10.1038/ng756
-
(2001)
Nat Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
38
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases
-
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum (2002) 46:3340-8. doi:10.1002/art.10688
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
-
39
-
-
0037249569
-
INFEVERS: the registry for FMF and hereditary inflammatory disorders mutations
-
de Menthière CS, Terrière S, Pugnère D, Ruiz M, Demaille J, Touitou I. INFEVERS: the registry for FMF and hereditary inflammatory disorders mutations. Nucleic Acids Res (2003) 31:282-5. doi:10.1093/nar/gkg031
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 282-285
-
-
de Menthière, C.S.1
Terrière, S.2
Pugnère, D.3
Ruiz, M.4
Demaille, J.5
Touitou, I.6
-
40
-
-
84940467473
-
Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry
-
Levy R, Gérard L, Kuemmerle-Deschner J, Lachmann HJ, Koné-Paut I, Cantarini L, et al. Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry. Ann Rheum Dis (2015) 74:2043-9. doi:10.1136/annrheumdis-2013-204991
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 2043-2049
-
-
Levy, R.1
Gérard, L.2
Kuemmerle-Deschner, J.3
Lachmann, H.J.4
Koné-Paut, I.5
Cantarini, L.6
-
41
-
-
66949115474
-
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity
-
Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, et al. Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. Immunity (2009) 30:875-87. doi:10.1016/j.immuni.2009.05.005
-
(2009)
Immunity
, vol.30
, pp. 875-887
-
-
Brydges, S.D.1
Mueller, J.L.2
McGeough, M.D.3
Pena, C.A.4
Misaghi, A.5
Gandhi, C.6
-
42
-
-
84864313288
-
Critical role for mast cells in interleukin-1beta-driven skin inflammation associated with an activating mutation in the NLRP3 protein
-
Nakamura Y, Franchi L, Kambe N, Meng G, Strober W, Nunez G, et al. Critical role for mast cells in interleukin-1beta-driven skin inflammation associated with an activating mutation in the NLRP3 protein. Immunity (2012) 37:85-95. doi:10.1016/j.immuni.2012.04.013
-
(2012)
Immunity
, vol.37
, pp. 85-95
-
-
Nakamura, Y.1
Franchi, L.2
Kambe, N.3
Meng, G.4
Strober, W.5
Nunez, G.6
-
43
-
-
66949175347
-
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
-
Meng G, Zhang F, Fuss I, Kitani A, Strober W. A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity (2009) 30:860-74. doi:10.1016/j.immuni.2009.04.012
-
(2009)
Immunity
, vol.30
, pp. 860-874
-
-
Meng, G.1
Zhang, F.2
Fuss, I.3
Kitani, A.4
Strober, W.5
-
44
-
-
85004010283
-
An NLRP3 mutation causes arthropathy and osteoporosis in humanized mice
-
Snouwaert JN, Nguyen M, Repenning PW, Dye R, Livingston EW, Kovarova M, et al. An NLRP3 mutation causes arthropathy and osteoporosis in humanized mice. Cell Rep (2016) 17:3077-88. doi:10.1016/j.celrep.2016.11.052
-
(2016)
Cell Rep
, vol.17
, pp. 3077-3088
-
-
Snouwaert, J.N.1
Nguyen, M.2
Repenning, P.W.3
Dye, R.4
Livingston, E.W.5
Kovarova, M.6
-
45
-
-
84887430028
-
Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies
-
Brydges SD, Broderick L, McGeough MD, Pena CA, Mueller JL, Hoffman HM. Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies. J Clin Invest (2013) 123:4695-705. doi:10.1172/JCI71543
-
(2013)
J Clin Invest
, vol.123
, pp. 4695-4705
-
-
Brydges, S.D.1
Broderick, L.2
McGeough, M.D.3
Pena, C.A.4
Mueller, J.L.5
Hoffman, H.M.6
-
46
-
-
44849122715
-
The infevers autoinflammatory mutation online registry: update with new genes and functions
-
Milhavet F, Cuisset L, Hoffman HM, Slim R, El-Shanti H, Aksentijevich I, et al. The infevers autoinflammatory mutation online registry: update with new genes and functions. Hum Mutat (2008) 29:803-8. doi:10.1002/humu.20720
-
(2008)
Hum Mutat
, vol.29
, pp. 803-808
-
-
Milhavet, F.1
Cuisset, L.2
Hoffman, H.M.3
Slim, R.4
El-Shanti, H.5
Aksentijevich, I.6
-
47
-
-
0034879079
-
Mutation frequency of familial Mediterranean fever and evidence for a high carrier rate in the Turkish population
-
Yilmaz E, Ozen S, Balci B, Duzova A, Topaloglu R, Besbas N, et al. Mutation frequency of familial Mediterranean fever and evidence for a high carrier rate in the Turkish population. Eur J Hum Genet (2001) 9:553-5. doi:10.1038/sj.ejhg.5200674
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 553-555
-
-
Yilmaz, E.1
Ozen, S.2
Balci, B.3
Duzova, A.4
Topaloglu, R.5
Besbas, N.6
-
48
-
-
84989246616
-
Familial Mediterranean fever patients homozygous for E148Q variant
-
Topaloglu R, Batu ED, Yildiz ç, Korkmaz E, özen S, Besbas N, et al. Familial Mediterranean fever patients homozygous for E148Q variant. Int J Rheum Dis (2016). doi:10.1111/1756-185X.12929
-
(2016)
Int J Rheum Dis
-
-
Topaloglu, R.1
Batu, E.D.2
Yildiz, Ç.3
Korkmaz, E.4
Özen, S.5
Besbas, N.6
-
49
-
-
79956299492
-
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1beta activation and severe autoinflammation in mice
-
Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, et al. Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1beta activation and severe autoinflammation in mice. Immunity (2011) 34:755-68. doi:10.1016/j.immuni.2011.02.020
-
(2011)
Immunity
, vol.34
, pp. 755-768
-
-
Chae, J.J.1
Cho, Y.H.2
Lee, G.S.3
Cheng, J.4
Liu, P.P.5
Feigenbaum, L.6
-
50
-
-
85009480842
-
IL-1β and caspase-1 drive autoinflammatory disease independently of IL-1a or caspase-8 in a mouse model of familial Mediterranean fever
-
Sharma D, Sharma BR, Vogel P, Kanneganti T-D. IL-1β and caspase-1 drive autoinflammatory disease independently of IL-1a or caspase-8 in a mouse model of familial Mediterranean fever. Am J Pathol (2016). doi:10.1016/j.ajpath.2016.10.015
-
(2016)
Am J Pathol
-
-
Sharma, D.1
Sharma, B.R.2
Vogel, P.3
Kanneganti, T.-D.4
-
51
-
-
84962744592
-
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
-
Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, et al. Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. Sci Transl Med (2016) 8:332ra45. doi:10.1126/scitranslmed.aaf1471
-
(2016)
Sci Transl Med
, vol.8
-
-
Masters, S.L.1
Lagou, V.2
Jéru, I.3
Baker, P.J.4
Van Eyck, L.5
Parry, D.A.6
-
52
-
-
84922008927
-
Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
-
Romberg N, Al Moussawi K, Nelson-Williams C, Stiegler AL, Loring E, Choi M, et al. Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation. Nat Genet (2014) 46:1135-9. doi:10.1038/ng.3066
-
(2014)
Nat Genet
, vol.46
, pp. 1135-1139
-
-
Romberg, N.1
Al Moussawi, K.2
Nelson-Williams, C.3
Stiegler, A.L.4
Loring, E.5
Choi, M.6
-
53
-
-
85008220560
-
Life-threatening NLRC4-associated hyperinflammation successfully treated with interleukin-18 inhibition
-
Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, et al. Life-threatening NLRC4-associated hyperinflammation successfully treated with interleukin-18 inhibition. J Allergy Clin Immunol (2016). doi:10.1016/j.jaci.2016.10.022
-
(2016)
J Allergy Clin Immunol
-
-
Canna, S.W.1
Girard, C.2
Malle, L.3
de Jesus, A.4
Romberg, N.5
Kelsen, J.6
-
54
-
-
84927126118
-
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
-
Canna SW, de Jesus AA, Gouni S, Brooks SR, Marrero B, Liu Y, et al. An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome. Nat Genet (2014) 46:1140-6. doi:10.1038/ng.3089
-
(2014)
Nat Genet
, vol.46
, pp. 1140-1146
-
-
Canna, S.W.1
de Jesus, A.A.2
Gouni, S.3
Brooks, S.R.4
Marrero, B.5
Liu, Y.6
-
55
-
-
84911922142
-
An inherited mutation in NLRC4 causes autoinflammation in human and mice
-
Kitamura A, Sasaki Y, Abe T, Kano H, Yasutomo K. An inherited mutation in NLRC4 causes autoinflammation in human and mice. J Exp Med (2014) 211:2385-96. doi:10.1084/jem.20141091
-
(2014)
J Exp Med
, vol.211
, pp. 2385-2396
-
-
Kitamura, A.1
Sasaki, Y.2
Abe, T.3
Kano, H.4
Yasutomo, K.5
-
56
-
-
40349113175
-
Mutations in NALP12 cause hereditary periodic fever syndromes
-
Jéru I, Duquesnoy P, Fernandes-Alnemri T, Cochet E, Yu JW, Lackmy-Port-Lis M, et al. Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci U S A (2008) 105:1614-9. doi:10.1073/pnas.0708616105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1614-1619
-
-
Jéru, I.1
Duquesnoy, P.2
Fernandes-Alnemri, T.3
Cochet, E.4
Yu, J.W.5
Lackmy-Port-Lis, M.6
-
57
-
-
84884928960
-
Rare NLRP12 variants associated with the NLRP12-autoinflammatory disorder phenotype: an Italian case series
-
Vitale A, Rigante D, Maggio MC, Emmi G, Romano M, Silvestri E, et al. Rare NLRP12 variants associated with the NLRP12-autoinflammatory disorder phenotype: an Italian case series. Clin Exp Rheumatol (2013) 31:155-6.
-
(2013)
Clin Exp Rheumatol
, vol.31
, pp. 155-156
-
-
Vitale, A.1
Rigante, D.2
Maggio, M.C.3
Emmi, G.4
Romano, M.5
Silvestri, E.6
-
58
-
-
79953702540
-
Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation
-
Borghini S, Tassi S, Chiesa S, Caroli F, Carta S, Caorsi R, et al. Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation. Arthritis Rheum (2011) 63:830-9. doi:10.1002/art.30170
-
(2011)
Arthritis Rheum
, vol.63
, pp. 830-839
-
-
Borghini, S.1
Tassi, S.2
Chiesa, S.3
Caroli, F.4
Carta, S.5
Caorsi, R.6
-
59
-
-
0034774916
-
Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever
-
Hoffman HM, Wanderer AA, Broide DH. Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever. J Allergy Clin Immunol (2001) 108:615-20. doi:10.1067/mai.2001.118790
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 615-620
-
-
Hoffman, H.M.1
Wanderer, A.A.2
Broide, D.H.3
-
60
-
-
67650736238
-
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease
-
Masters SL, Simon A, Aksentijevich I, Kastner DL. Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease. Annu Rev Immunol (2009) 27:621-68. doi:10.1146/annurev.immunol.25.022106.141627
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 621-668
-
-
Masters, S.L.1
Simon, A.2
Aksentijevich, I.3
Kastner, D.L.4
-
61
-
-
84858796861
-
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
-
Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, et al. An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity (2012) 36:464-76. doi:10.1016/j.immuni.2012.02.001
-
(2012)
Immunity
, vol.36
, pp. 464-476
-
-
Khare, S.1
Dorfleutner, A.2
Bryan, N.B.3
Yun, C.4
Radian, A.D.5
de Almeida, L.6
-
62
-
-
84866496690
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
Vladimer GI, Weng D, Paquette SWM, Vanaja SK, Rathinam VAK, Aune MH, et al. The NLRP12 inflammasome recognizes Yersinia pestis. Immunity (2012) 37:96-107. doi:10.1016/j.immuni.2012.07.006
-
(2012)
Immunity
, vol.37
, pp. 96-107
-
-
Vladimer, G.I.1
Weng, D.2
Paquette, S.W.M.3
Vanaja, S.K.4
Rathinam, V.A.K.5
Aune, M.H.6
-
63
-
-
0037852184
-
Cutting edge: monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes
-
Williams KL, Taxman DJ, Linhoff MW, Reed W, Ting JP. Cutting edge: monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. J Immunol (2003) 170:5354-8. doi:10.4049/jimmunol.170.11.5354
-
(2003)
J Immunol
, vol.170
, pp. 5354-5358
-
-
Williams, K.L.1
Taxman, D.J.2
Linhoff, M.W.3
Reed, W.4
Ting, J.P.5
-
64
-
-
79955566751
-
Identification and functional consequences of a recurrent NLRP12 missense mutation in periodic fever syndromes
-
Jeru I, Le Borgne G, Cochet E, Hayrapetyan H, Duquesnoy P, Grateau G, et al. Identification and functional consequences of a recurrent NLRP12 missense mutation in periodic fever syndromes. Arthritis Rheum (2011) 63:1459-64. doi:10.1002/art.30241
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1459-1464
-
-
Jeru, I.1
Le Borgne, G.2
Cochet, E.3
Hayrapetyan, H.4
Duquesnoy, P.5
Grateau, G.6
-
65
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol (2006) 7:569-75. doi:10.1038/ni1344
-
(2006)
Nat Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
-
66
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A (2010) 107:3076-80. doi:10.1073/pnas.0913087107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
-
67
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature (2011) 477:592-5. doi:10.1038/nature10394
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
68
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature (2011) 477:596-600. doi:10.1038/nature10510
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
-
69
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature (2004) 430:213-8. doi:10.1038/nature02664
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
70
-
-
85019005737
-
A disease-associated mutant of NLRC4 shows enhanced interaction with SUG1 leading to constitutive FADD dependent caspase-8 activation and cell death
-
Raghawan AK, Sripada A, Gopinath G, Pushpanjali P, Kumar Y, Radha V, et al. A disease-associated mutant of NLRC4 shows enhanced interaction with SUG1 leading to constitutive FADD dependent caspase-8 activation and cell death. J Biol Chem (2016). doi:10.1074/jbc.M116.763979
-
(2016)
J Biol Chem
-
-
Raghawan, A.K.1
Sripada, A.2
Gopinath, G.3
Pushpanjali, P.4
Kumar, Y.5
Radha, V.6
-
71
-
-
84901008921
-
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
-
Man SM, Hopkins LJ, Nugent E, Cox S, Gluck IM, Tourlomousis P, et al. Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex. Proc Natl Acad Sci U S A (2014) 111:7403-8. doi:10.1073/pnas.1402911111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 7403-7408
-
-
Man, S.M.1
Hopkins, L.J.2
Nugent, E.3
Cox, S.4
Gluck, I.M.5
Tourlomousis, P.6
-
72
-
-
30844432876
-
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization
-
Yu JW, Wu J, Zhang Z, Datta P, Ibrahimi I, Taniguchi S, et al. Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. Cell Death Differ (2006) 13:236-49. doi:10.1038/sj.cdd.4401734
-
(2006)
Cell Death Differ
, vol.13
, pp. 236-249
-
-
Yu, J.W.1
Wu, J.2
Zhang, Z.3
Datta, P.4
Ibrahimi, I.5
Taniguchi, S.6
-
73
-
-
84907270863
-
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome
-
Xu H, Yang J, Gao W, Li L, Li P, Zhang L, et al. Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome. Nature (2014) 513:237-41. doi:10.1038/nature13449
-
(2014)
Nature
, vol.513
, pp. 237-241
-
-
Xu, H.1
Yang, J.2
Gao, W.3
Li, L.4
Li, P.5
Zhang, L.6
-
74
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, Niikawa N, et al. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J Biol Chem (1999) 274:33835-8. doi:10.1074/jbc.274.48.33835
-
(1999)
J Biol Chem
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
-
75
-
-
34548031870
-
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ (2007) 14:1590-604. doi:10.1038/sj.cdd.4402194
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
-
76
-
-
84871314266
-
Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein
-
Vajjhala PR, Mirams RE, Hill JM. Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. J Biol Chem (2012) 287:41732-43. doi:10.1074/jbc.M112.381228
-
(2012)
J Biol Chem
, vol.287
, pp. 41732-41743
-
-
Vajjhala, P.R.1
Mirams, R.E.2
Hill, J.M.3
-
77
-
-
84896332642
-
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
-
Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, et al. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell (2014) 156:1193-206. doi:10.1016/j.cell.2014.02.008
-
(2014)
Cell
, vol.156
, pp. 1193-1206
-
-
Lu, A.1
Magupalli, V.G.2
Ruan, J.3
Yin, Q.4
Atianand, M.K.5
Vos, M.R.6
-
78
-
-
84896381627
-
Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation
-
Cai X, Chen J, Xu H, Liu S, Jiang QX, Halfmann R, et al. Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation. Cell (2014) 156:1207-22. doi:10.1016/j.cell.2014.01.063
-
(2014)
Cell
, vol.156
, pp. 1207-1222
-
-
Cai, X.1
Chen, J.2
Xu, H.3
Liu, S.4
Jiang, Q.X.5
Halfmann, R.6
-
79
-
-
84945567425
-
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy
-
Sborgi L, Ravotti F, Dandey VP, Dick MS, Mazur A, Reckel S, et al. Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proc Natl Acad Sci U S A (2015) 112:13237-42. doi:10.1073/pnas.1507579112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 13237-13242
-
-
Sborgi, L.1
Ravotti, F.2
Dandey, V.P.3
Dick, M.S.4
Mazur, A.5
Reckel, S.6
-
80
-
-
84969261036
-
A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly
-
Schmidt FI, Lu A, Chen JW, Ruan J, Tang C, Wu H, et al. A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J Exp Med (2016) 213:771-90. doi:10.1084/jem.20151790
-
(2016)
J Exp Med
, vol.213
, pp. 771-790
-
-
Schmidt, F.I.1
Lu, A.2
Chen, J.W.3
Ruan, J.4
Tang, C.5
Wu, H.6
-
81
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
Srinivasula SM, Poyet JL, Razmara M, Datta P, Zhang Z, Alnemri ES. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J Biol Chem (2002) 277:21119-22. doi:10.1074/jbc.C200179200
-
(2002)
J Biol Chem
, vol.277
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
82
-
-
84969142199
-
Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death
-
Sanman LE, Qian Y, Eisele NA, Ng TM, van der Linden WA, Monack DM, et al. Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. Elife (2016) 5:e13663. doi:10.7554/eLife.13663
-
(2016)
Elife
, vol.5
-
-
Sanman, L.E.1
Qian, Y.2
Eisele, N.A.3
Ng, T.M.4
van der Linden, W.A.5
Monack, D.M.6
-
83
-
-
84975453384
-
The cell biology of inflammasomes: mechanisms of inflammasome activation and regulation
-
Sharma D, Kanneganti TD. The cell biology of inflammasomes: mechanisms of inflammasome activation and regulation. J Cell Biol (2016) 213:617-29. doi:10.1083/jcb.201602089
-
(2016)
J Cell Biol
, vol.213
, pp. 617-629
-
-
Sharma, D.1
Kanneganti, T.D.2
-
84
-
-
85010916994
-
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation
-
Próchnicki T, Mangan MS, Latz E. Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation. F1000Research (2016) 5:1-15. doi:10.12688/f1000research.8614.1
-
(2016)
F1000Research
, vol.5
, pp. 1-15
-
-
Próchnicki, T.1
Mangan, M.S.2
Latz, E.3
-
85
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 440:228-32. doi:10.1038/nature04515
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
86
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
-
Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 25:5071-82. doi:10.1038/sj.emboj.7601378
-
(2006)
EMBO J
, vol.25
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
87
-
-
84859515412
-
Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages
-
Luheshi NM, Giles JA, Lopez-Castejon G, Brough D. Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages. Eur J Immunol (2012) 42:716-25. doi:10.1002/eji.201142079
-
(2012)
Eur J Immunol
, vol.42
, pp. 716-725
-
-
Luheshi, N.M.1
Giles, J.A.2
Lopez-Castejon, G.3
Brough, D.4
-
88
-
-
84927669849
-
K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling
-
Katsnelson MA, Rucker LG, Russo HM, Dubyak GR. K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling. J Immunol (2015) 194:3937-52. doi:10.4049/jimmunol.1402658
-
(2015)
J Immunol
, vol.194
, pp. 3937-3952
-
-
Katsnelson, M.A.1
Rucker, L.G.2
Russo, H.M.3
Dubyak, G.R.4
-
89
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo R, Kuffa P, Martinez-Colon G, Smith BL, Rajendiran TM, Nunez G. K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity (2013) 38:1142-53. doi:10.1016/j.immuni.2013.05.016
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
90
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ (2007) 14:1583-9. doi:10.1038/sj.cdd.4402195
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
91
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, et al. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A (2012) 109:11282-7. doi:10.1073/pnas.1117765109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
-
92
-
-
84870508924
-
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
-
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature (2012) 492:123-7. doi:10.1038/nature11588
-
(2012)
Nature
, vol.492
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
-
93
-
-
84871797522
-
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
-
Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, et al. Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun (2012) 3:1329. doi:10.1038/ncomms2339
-
(2012)
Nat Commun
, vol.3
, pp. 1329
-
-
Rossol, M.1
Pierer, M.2
Raulien, N.3
Quandt, D.4
Meusch, U.5
Rothe, K.6
-
94
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 9:847-56. doi:10.1038/ni.1631
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
95
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, et al. ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis (2012) 3:e261. doi:10.1038/cddis.2011.132
-
(2012)
Cell Death Dis
, vol.3
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
-
96
-
-
84941652089
-
Endoplasmic reticulum stress activates the inflammasome via NLRP3-and caspase-2-driven mitochondrial damage
-
Bronner DN, Abuaita BH, Chen X, Fitzgerald KA, Nunez G, He Y, et al. Endoplasmic reticulum stress activates the inflammasome via NLRP3-and caspase-2-driven mitochondrial damage. Immunity (2015) 43:451-62. doi:10.1016/j.immuni.2015.08.008
-
(2015)
Immunity
, vol.43
, pp. 451-462
-
-
Bronner, D.N.1
Abuaita, B.H.2
Chen, X.3
Fitzgerald, K.A.4
Nunez, G.5
He, Y.6
-
97
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature (2011) 469:221-5. doi:10.1038/nature09663
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
98
-
-
84975292510
-
K(+) regulates Ca(2+) to drive inflammasome signaling: dynamic visualization of ion flux in live cells
-
Yaron JR, Gangaraju S, Rao MY, Kong X, Zhang L, Su F, et al. K(+) regulates Ca(2+) to drive inflammasome signaling: dynamic visualization of ion flux in live cells. Cell Death Dis (2015) 6:e1954. doi:10.1038/cddis.2015.277
-
(2015)
Cell Death Dis
, vol.6
-
-
Yaron, J.R.1
Gangaraju, S.2
Rao, M.Y.3
Kong, X.4
Zhang, L.5
Su, F.6
-
99
-
-
84876237736
-
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
-
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell (2013) 153:348-61. doi:10.1016/j.cell.2013.02.054
-
(2013)
Cell
, vol.153
, pp. 348-361
-
-
Subramanian, N.1
Natarajan, K.2
Clatworthy, M.R.3
Wang, Z.4
Germain, R.N.5
-
100
-
-
84876567161
-
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
-
Misawa T, Takahama M, Kozaki T, Lee H, Zou J, Saitoh T, et al. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat Immunol (2013) 14:454-60. doi:10.1038/ni.2550
-
(2013)
Nat Immunol
, vol.14
, pp. 454-460
-
-
Misawa, T.1
Takahama, M.2
Kozaki, T.3
Lee, H.4
Zou, J.5
Saitoh, T.6
-
101
-
-
84882614243
-
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation
-
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, et al. Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity (2013) 39:311-23. doi:10.1016/j.immuni.2013.08.001
-
(2013)
Immunity
, vol.39
, pp. 311-323
-
-
Iyer, S.S.1
He, Q.2
Janczy, J.R.3
Elliott, E.I.4
Zhong, Z.5
Olivier, A.K.6
-
102
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2011) 12:222-30. doi:10.1038/ni.1980
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
103
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity (2012) 36:401-14. doi:10.1016/j.immuni.2012.01.009
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
-
104
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature (2011) 479:117-21. doi:10.1038/nature10558
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
105
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature (2014) 514:187-92. doi:10.1038/nature13683
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
-
106
-
-
84947441282
-
Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock
-
Yang D, He Y, Muñoz-Planillo R, Liu Q, Núñez G. Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock. Immunity (2015) 43:923-32. doi:10.1016/j.immuni.2015.10.009
-
(2015)
Immunity
, vol.43
, pp. 923-932
-
-
Yang, D.1
He, Y.2
Muñoz-Planillo, R.3
Liu, Q.4
Núñez, G.5
-
107
-
-
84943198707
-
Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells
-
Schmid-Burgk JL, Gaidt MM, Schmidt T, Ebert TS, Bartok E, Hornung V. Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells. Eur J Immunol (2015) 45:2911-7. doi:10.1002/eji.201545523
-
(2015)
Eur J Immunol
, vol.45
, pp. 2911-2917
-
-
Schmid-Burgk, J.L.1
Gaidt, M.M.2
Schmidt, T.3
Ebert, T.S.4
Bartok, E.5
Hornung, V.6
-
108
-
-
84943200249
-
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux
-
Rühl S, Broz P. Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux. Eur J Immunol (2015) 45:2927-36. doi:10.1002/eji.201545772
-
(2015)
Eur J Immunol
, vol.45
, pp. 2927-2936
-
-
Rühl, S.1
Broz, P.2
-
109
-
-
84860225554
-
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals
-
Shenoy AR, Wellington DA, Kumar P, Kassa H, Booth CJ, Cresswell P, et al. GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (2012) 336:481-5. doi:10.1126/science.1217141
-
(2012)
Science
, vol.336
, pp. 481-485
-
-
Shenoy, A.R.1
Wellington, D.A.2
Kumar, P.3
Kassa, H.4
Booth, C.J.5
Cresswell, P.6
-
110
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem (2012) 287:36617-22. doi:10.1074/jbc.M112.407130
-
(2012)
J Biol Chem
, vol.287
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
111
-
-
84873834109
-
Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome
-
Lopez-Castejon G, Luheshi NM, Compan V, High S, Whitehead RC, Flitsch S, et al. Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome. J Biol Chem (2013) 288:2721-33. doi:10.1074/jbc.M112.422238
-
(2013)
J Biol Chem
, vol.288
, pp. 2721-2733
-
-
Lopez-Castejon, G.1
Luheshi, N.M.2
Compan, V.3
High, S.4
Whitehead, R.C.5
Flitsch, S.6
-
112
-
-
84872782298
-
Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
-
Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell (2013) 49:331-8. doi:10.1016/j.molcel.2012.11.009
-
(2013)
Mol Cell
, vol.49
, pp. 331-338
-
-
Py, B.F.1
Kim, M.S.2
Vakifahmetoglu-Norberg, H.3
Yuan, J.4
-
113
-
-
84952931119
-
A genome-wide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation
-
Schmid-Burgk JL, Chauhan D, Schmidt T, Ebert TS, Reinhardt J, Endl E, et al. A genome-wide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation. J Biol Chem (2016) 291:103-9. doi:10.1074/jbc.C115.700492
-
(2016)
J Biol Chem
, vol.291
, pp. 103-109
-
-
Schmid-Burgk, J.L.1
Chauhan, D.2
Schmidt, T.3
Ebert, T.S.4
Reinhardt, J.5
Endl, E.6
-
114
-
-
84958971929
-
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
-
He Y, Zeng MY, Yang D, Motro B, Nunez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature (2016) 530:354-7. doi:10.1038/nature16959
-
(2016)
Nature
, vol.530
, pp. 354-357
-
-
He, Y.1
Zeng, M.Y.2
Yang, D.3
Motro, B.4
Nunez, G.5
-
115
-
-
84949595485
-
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
-
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat Immunol (2016) 17:250-8. doi:10.1038/ni.3333
-
(2016)
Nat Immunol
, vol.17
, pp. 250-258
-
-
Shi, H.1
Wang, Y.2
Li, X.3
Zhan, X.4
Tang, M.5
Fina, M.6
-
116
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol (2009) 183:787-91. doi:10.4049/jimmunol.0901363
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
-
117
-
-
70249110860
-
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
-
Franchi L, Eigenbrod T, Nunez G. Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol (2009) 183:792-6. doi:10.4049/jimmunol.0900173
-
(2009)
J Immunol
, vol.183
, pp. 792-796
-
-
Franchi, L.1
Eigenbrod, T.2
Nunez, G.3
-
118
-
-
84867304098
-
NLRP3 inflammasome activity is negatively controlled by miR-223
-
Bauernfeind F, Rieger A, Schildberg FA, Knolle PA, Schmid-Burgk JL, Hornung V. NLRP3 inflammasome activity is negatively controlled by miR-223. J Immunol (2012) 189:4175-81. doi:10.4049/jimmunol.1201516
-
(2012)
J Immunol
, vol.189
, pp. 4175-4181
-
-
Bauernfeind, F.1
Rieger, A.2
Schildberg, F.A.3
Knolle, P.A.4
Schmid-Burgk, J.L.5
Hornung, V.6
-
119
-
-
84871188736
-
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta
-
Mishra BB, Rathinam VA, Martens GW, Martinot AJ, Kornfeld H, Fitzgerald KA, et al. Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta. Nat Immunol (2013) 14:52-60. doi:10.1038/ni.2474
-
(2013)
Nat Immunol
, vol.14
, pp. 52-60
-
-
Mishra, B.B.1
Rathinam, V.A.2
Martens, G.W.3
Martinot, A.J.4
Kornfeld, H.5
Fitzgerald, K.A.6
-
120
-
-
84873710963
-
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
-
Mao K, Chen S, Chen M, Ma Y, Wang Y, Huang B, et al. Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 23:201-12. doi:10.1038/cr.2013.6
-
(2013)
Cell Res
, vol.23
, pp. 201-212
-
-
Mao, K.1
Chen, S.2
Chen, M.3
Ma, Y.4
Wang, Y.5
Huang, B.6
-
121
-
-
84885964931
-
Pyrin-and CARD-only proteins as regulators of NLR functions
-
Le HT, Harton JA. Pyrin-and CARD-only proteins as regulators of NLR functions. Front Immunol (2013) 4:275. doi:10.3389/fimmu.2013.00275
-
(2013)
Front Immunol
, vol.4
, pp. 275
-
-
Le, H.T.1
Harton, J.A.2
-
122
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production
-
Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, et al. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci U S A (2006) 103:9982-7. doi:10.1073/pnas.0602081103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
Smith, B.J.6
-
123
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ (2007) 14:1457-66. doi:10.1038/sj.cdd.4402142
-
(2007)
Cell Death Differ
, vol.14
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
Beer, H.D.6
-
124
-
-
84870595842
-
Genetic loss of murine pyrin, the familial Mediterranean fever protein, increases interleukin-1beta levels
-
Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH. Genetic loss of murine pyrin, the familial Mediterranean fever protein, increases interleukin-1beta levels. PLoS One (2012) 7:e51105. doi:10.1371/journal.pone.0051105
-
(2012)
PLoS One
, vol.7
-
-
Hesker, P.R.1
Nguyen, M.2
Kovarova, M.3
Ting, J.P.4
Koller, B.H.5
-
125
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, et al. Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol (2012) 13:255-63. doi:10.1038/ni.2215
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
-
126
-
-
84923325462
-
Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy
-
Jabir MS, Hopkins L, Ritchie ND, Ullah I, Bayes HK, Li D, et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy (2015) 11:166-82. doi:10.4161/15548627.2014.981915
-
(2015)
Autophagy
, vol.11
, pp. 166-182
-
-
Jabir, M.S.1
Hopkins, L.2
Ritchie, N.D.3
Ullah, I.4
Bayes, H.K.5
Li, D.6
-
127
-
-
84959420149
-
NF-kappaB restricts inflammasome activation via elimination of damaged mitochondria
-
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, et al. NF-kappaB restricts inflammasome activation via elimination of damaged mitochondria. Cell (2016) 164:896-910. doi:10.1016/j.cell.2015.12.057
-
(2016)
Cell
, vol.164
, pp. 896-910
-
-
Zhong, Z.1
Umemura, A.2
Sanchez-Lopez, E.3
Liang, S.4
Shalapour, S.5
Wong, J.6
-
128
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, et al. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem (2011) 286:9587-97. doi:10.1074/jbc.M110.202911
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
-
129
-
-
84929643541
-
Prostaglandin E2 inhibits NLRP3 inflammasome activation through EP4 receptor and intracellular cyclic AMP in human macrophages
-
Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, et al. Prostaglandin E2 inhibits NLRP3 inflammasome activation through EP4 receptor and intracellular cyclic AMP in human macrophages. J Immunol (2015) 194:5472-87. doi:10.4049/jimmunol.1401343
-
(2015)
J Immunol
, vol.194
, pp. 5472-5487
-
-
Sokolowska, M.1
Chen, L.Y.2
Liu, Y.3
Martinez-Anton, A.4
Qi, H.Y.5
Logun, C.6
-
130
-
-
84920990887
-
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome
-
Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, et al. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell (2015) 160:62-73. doi:10.1016/j.cell.2014.11.047
-
(2015)
Cell
, vol.160
, pp. 62-73
-
-
Yan, Y.1
Jiang, W.2
Liu, L.3
Wang, X.4
Ding, C.5
Tian, Z.6
-
131
-
-
84983525884
-
NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations
-
Mortimer L, Moreau F, MacDonald JA, Chadee K. NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations. Nat Immunol (2016) 17:1176-86. doi:10.1038/ni.3538
-
(2016)
Nat Immunol
, vol.17
, pp. 1176-1186
-
-
Mortimer, L.1
Moreau, F.2
MacDonald, J.A.3
Chadee, K.4
-
132
-
-
84976329660
-
Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
-
Park YH, Wood G, Kastner DL, Chae JJ. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol (2016) 17:914-21. doi:10.1038/ni.3457
-
(2016)
Nat Immunol
, vol.17
, pp. 914-921
-
-
Park, Y.H.1
Wood, G.2
Kastner, D.L.3
Chae, J.J.4
-
133
-
-
85005992585
-
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
-
Van Gorp H, Saavedra PHV, de Vasconcelos NM, Van Opdenbosch N, Vande Walle L, Matusiak M, et al. Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation. Proc Natl Acad Sci U S A (2016) 113:14384-9. doi:10.1073/pnas.1613156113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 14384-14389
-
-
Van Gorp, H.1
Saavedra, P.H.V.2
de Vasconcelos, N.M.3
Van Opdenbosch, N.4
Vande Walle, L.5
Matusiak, M.6
-
134
-
-
84982091531
-
Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation
-
Gao W, Yang J, Liu W, Wang Y, Shao F. Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation. Proc Natl Acad Sci U S A (2016) 113:E4857-66. doi:10.1073/pnas.1601700113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E4857-E4866
-
-
Gao, W.1
Yang, J.2
Liu, W.3
Wang, Y.4
Shao, F.5
-
135
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity (2013) 39:1003-18. doi:10.1016/j.immuni.2013.11.010
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
137
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes
-
Andrei C, Margiocco P, Poggi A, Lotti LV, Torrisi MR, Rubartelli A. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes. Proc Natl Acad Sci U S A (2004) 101:9745-50. doi:10.1073/pnas.0308558101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
Margiocco, P.2
Poggi, A.3
Lotti, L.V.4
Torrisi, M.R.5
Rubartelli, A.6
-
138
-
-
34548614009
-
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
-
Qu Y, Franchi L, Nunez G, Dubyak GR. Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol (2007) 179:1913-25. doi:10.4049/jimmunol.179.3.1913
-
(2007)
J Immunol
, vol.179
, pp. 1913-1925
-
-
Qu, Y.1
Franchi, L.2
Nunez, G.3
Dubyak, G.R.4
-
139
-
-
0035655395
-
Rapid secretion of interleukin-1β by microvesicle shedding
-
MacKenzie A, Wilson HL, Kiss-Toth E, Dower SK, North RA, Surprenant A. Rapid secretion of interleukin-1β by microvesicle shedding. Immunity (2001) 15:825-35. doi:10.1016/S1074-7613(01)00229-1
-
(2001)
Immunity
, vol.15
, pp. 825-835
-
-
MacKenzie, A.1
Wilson, H.L.2
Kiss-Toth, E.3
Dower, S.K.4
North, R.A.5
Surprenant, A.6
-
140
-
-
84949091051
-
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
-
He W, Wan H, Hu L, Chen P, Wang X, Huang Z, et al. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. Cell Res (2015) 25:1285-98. doi:10.1038/cr.2015.139
-
(2015)
Cell Res
, vol.25
, pp. 1285-1298
-
-
He, W.1
Wan, H.2
Hu, L.3
Chen, P.4
Wang, X.5
Huang, Z.6
-
141
-
-
84978419608
-
Pore-forming activity and structural autoinhibition of the gasdermin family
-
Ding J, Wang K, Liu W, She Y, Sun Q, Shi J, et al. Pore-forming activity and structural autoinhibition of the gasdermin family. Nature (2016) 535:111-6. doi:10.1038/nature18590
-
(2016)
Nature
, vol.535
, pp. 111-116
-
-
Ding, J.1
Wang, K.2
Liu, W.3
She, Y.4
Sun, Q.5
Shi, J.6
-
142
-
-
84978374487
-
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
-
Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature (2016) 535:153-8. doi:10.1038/nature18629
-
(2016)
Nature
, vol.535
, pp. 153-158
-
-
Liu, X.1
Zhang, Z.2
Ruan, J.3
Pan, Y.4
Magupalli, V.G.5
Wu, H.6
-
143
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature (2015) 526:660-5. doi:10.1038/nature15514
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
-
144
-
-
84957922975
-
Inflammasome-dependent IL-1 β release depends upon membrane permeabilisation
-
Martín-Sánchez F, Diamond C, Zeitler M, Gomez-Sánchez A, Peñalver M, Paszek P, et al. Inflammasome-dependent IL-1 β release depends upon membrane permeabilisation. Cell Death Differ (2016) 23:1219-31. doi:10.1038/cdd.2015.176
-
(2016)
Cell Death Differ
, vol.23
, pp. 1219-1231
-
-
Martín-Sánchez, F.1
Diamond, C.2
Zeitler, M.3
Gomez-Sánchez, A.4
Peñalver, M.5
Paszek, P.6
-
145
-
-
84904792729
-
The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute salmonella challenge
-
Chen KWW, Groß CJJ, Sotomayor FV, Stacey KJJ, Tschopp JJ, Sweet MJJ, et al. The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute salmonella challenge. Cell Rep (2014) 8:570-82. doi:10.1016/j.celrep.2014.06.028
-
(2014)
Cell Rep
, vol.8
, pp. 570-582
-
-
Chen, K.W.W.1
Groß, C.J.J.2
Sotomayor, F.V.3
Stacey, K.J.J.4
Tschopp, J.J.5
Sweet, M.J.J.6
-
146
-
-
84958230881
-
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
-
Karmakar M, Katsnelson MA, Dubyak GR, Pearlman E. Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP. Nat Commun (2016) 7:10555. doi:10.1038/ncomms10555
-
(2016)
Nat Commun
, vol.7
, pp. 10555
-
-
Karmakar, M.1
Katsnelson, M.A.2
Dubyak, G.R.3
Pearlman, E.4
-
147
-
-
84927628632
-
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling
-
de Jesus AA, Canna SW, Liu Y, Goldbach-Mansky R. Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling. Annu Rev Immunol (2015) 33:823-74. doi:10.1146/annurev-immunol-032414-112227
-
(2015)
Annu Rev Immunol
, vol.33
, pp. 823-874
-
-
de Jesus, A.A.1
Canna, S.W.2
Liu, Y.3
Goldbach-Mansky, R.4
-
148
-
-
79951517164
-
Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France
-
Cuisset L, Jeru I, Dumont B, Fabre A, Cochet E, Le Bozec J, et al. Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France. Ann Rheum Dis (2011) 70:495-9. doi:10.1136/ard.2010.138420
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 495-499
-
-
Cuisset, L.1
Jeru, I.2
Dumont, B.3
Fabre, A.4
Cochet, E.5
Le Bozec, J.6
-
149
-
-
73649189052
-
Urticaria, deafness, and amyloidosis: a new heredo-familial syndrome
-
Muckle TJ, Wells M. Urticaria, deafness, and amyloidosis: a new heredo-familial syndrome. Q J Med (1962) 31:235-48.
-
(1962)
Q J Med
, vol.31
, pp. 235-248
-
-
Muckle, T.J.1
Wells, M.2
-
150
-
-
0023894493
-
A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients
-
Prieur AM, Griscelli C, Lampert F, Truckenbrodt H, Guggenheim MA, Lovell DJ, et al. A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients. Scand J Rheumatol Suppl (1987) 66:57-68. doi:10.3109/03009748709102523
-
(1987)
Scand J Rheumatol Suppl
, vol.66
, pp. 57-68
-
-
Prieur, A.M.1
Griscelli, C.2
Lampert, F.3
Truckenbrodt, H.4
Guggenheim, M.A.5
Lovell, D.J.6
-
151
-
-
34247252063
-
The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model
-
Aksentijevich I, D Putnam C, Remmers EF, Mueller JL, Le J, Kolodner RD, et al. The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model. Arthritis Rheum (2007) 56:1273-85. doi:10.1002/art.22491
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1273-1285
-
-
Aksentijevich, I.1
Putnam, D.C.2
Remmers, E.F.3
Mueller, J.L.4
Le, J.5
Kolodner, R.D.6
-
152
-
-
84973294771
-
Neurology of the cryopyrin-associated periodic fever syndrome
-
Parker T, Keddie S, Kidd D, Lane T, Maviki M, Hawkins PN, et al. Neurology of the cryopyrin-associated periodic fever syndrome. Eur J Neurol (2016) 23:1145-51. doi:10.1111/ene.12965
-
(2016)
Eur J Neurol
, vol.23
, pp. 1145-1151
-
-
Parker, T.1
Keddie, S.2
Kidd, D.3
Lane, T.4
Maviki, M.5
Hawkins, P.N.6
-
153
-
-
84946098673
-
Musculoskeletal symptoms in patients with cryopyrin-associated periodic syndromes: a large database study
-
Houx L, Hachulla E, Kone-Paut I, Quartier P, Touitou I, Guennoc X, et al. Musculoskeletal symptoms in patients with cryopyrin-associated periodic syndromes: a large database study. Arthritis Rheumatol (2015) 67:3027-36. doi:10.1002/art.39292
-
(2015)
Arthritis Rheumatol
, vol.67
, pp. 3027-3036
-
-
Houx, L.1
Hachulla, E.2
Kone-Paut, I.3
Quartier, P.4
Touitou, I.5
Guennoc, X.6
-
154
-
-
80155148684
-
High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study
-
Tanaka N, Izawa K, Saito MK, Sakuma M, Oshima K, Ohara O, et al. High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study. Arthritis Rheum (2011) 63:3625-32. doi:10.1002/art.30512
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3625-3632
-
-
Tanaka, N.1
Izawa, K.2
Saito, M.K.3
Sakuma, M.4
Oshima, K.5
Ohara, O.6
-
155
-
-
84922464191
-
Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes
-
Nakagawa K, Gonzalez-Roca E, Souto A, Kawai T, Umebayashi H, Campistol JM, et al. Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes. Ann Rheum Dis (2015) 74:603-10. doi:10.1136/annrheumdis-2013-204361
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 603-610
-
-
Nakagawa, K.1
Gonzalez-Roca, E.2
Souto, A.3
Kawai, T.4
Umebayashi, H.5
Campistol, J.M.6
-
156
-
-
84997712052
-
Late onset cryopyrin-associated periodic syndrome due to myeloid-restricted somatic NLRP3 mosaicism
-
Mensa-Vilaro A, Teresa Bosque M, Magri G, Honda Y, Martínez-Banaclocha H, Casorran-Berges M, et al. Late onset cryopyrin-associated periodic syndrome due to myeloid-restricted somatic NLRP3 mosaicism. Arthritis Rheumatol (2016) 68:3035-41. doi:10.1002/art.39770
-
(2016)
Arthritis Rheumatol
, vol.68
, pp. 3035-3041
-
-
Mensa-Vilaro, A.1
Teresa Bosque, M.2
Magri, G.3
Honda, Y.4
Martínez-Banaclocha, H.5
Casorran-Berges, M.6
-
157
-
-
77953105116
-
Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1 secretion
-
Tassi S, Carta S, Delfino L, Caorsi R, Martini A, Gattorno M, et al. Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1 secretion. Proc Natl Acad Sci U S A (2010) 107:9789-94. doi:10.1073/pnas.1000779107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9789-9794
-
-
Tassi, S.1
Carta, S.2
Delfino, L.3
Caorsi, R.4
Martini, A.5
Gattorno, M.6
-
158
-
-
84864867958
-
Deficient production of IL-1 receptor antagonist and IL-6 coupled to oxidative stress in cryopyrin-associated periodic syndrome monocytes
-
Carta S, Tassi S, Delfino L, Omenetti A, Raffa S, Torrisi MR, et al. Deficient production of IL-1 receptor antagonist and IL-6 coupled to oxidative stress in cryopyrin-associated periodic syndrome monocytes. Ann Rheum Dis (2012) 71:1577-81. doi:10.1136/annrheumdis-2012-201340
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1577-1581
-
-
Carta, S.1
Tassi, S.2
Delfino, L.3
Omenetti, A.4
Raffa, S.5
Torrisi, M.R.6
-
159
-
-
84924191070
-
Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance
-
Carta S, Penco F, Lavieri R, Martini A, Dinarello CA, Gattorno M, et al. Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance. Proc Natl Acad Sci U S A (2015) 112:2835-40. doi:10.1073/pnas.1424741112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 2835-2840
-
-
Carta, S.1
Penco, F.2
Lavieri, R.3
Martini, A.4
Dinarello, C.A.5
Gattorno, M.6
-
160
-
-
84891747893
-
Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype
-
Omenetti A, Carta S, Delfino L, Martini A, Gattorno M, Rubartelli A. Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype. Ann Rheum Dis (2014) 73:462-9. doi:10.1136/annrheumdis-2012-202774
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 462-469
-
-
Omenetti, A.1
Carta, S.2
Delfino, L.3
Martini, A.4
Gattorno, M.5
Rubartelli, A.6
-
161
-
-
0032574208
-
Familial Mediterranean fever
-
Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet (1998) 351:659-64. doi:10.1016/S0140-6736(97)09408-7
-
(1998)
Lancet
, vol.351
, pp. 659-664
-
-
Ben-Chetrit, E.1
Levy, M.2
-
162
-
-
66449090908
-
Clinical disease among patients heterozygous for familial Mediterranean fever
-
Marek-Yagel D, Berkun Y, Padeh S, Abu A, Reznik-Wolf H, Livneh A, et al. Clinical disease among patients heterozygous for familial Mediterranean fever. Arthritis Rheum (2009) 60:1862-6. doi:10.1002/art.24570
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1862-1866
-
-
Marek-Yagel, D.1
Berkun, Y.2
Padeh, S.3
Abu, A.4
Reznik-Wolf, H.5
Livneh, A.6
-
163
-
-
12344314454
-
Familial Mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study
-
Tunca M, Akar S, Onen F, Ozdogan H, Kasapcopur O, Yalcinkaya F, et al. Familial Mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study. Medicine (Baltimore) (2005) 84:1-11. doi:10.1097/01.md.0000152370.84628.0c
-
(2005)
Medicine (Baltimore)
, vol.84
, pp. 1-11
-
-
Tunca, M.1
Akar, S.2
Onen, F.3
Ozdogan, H.4
Kasapcopur, O.5
Yalcinkaya, F.6
-
164
-
-
84940438436
-
Non-canonical manifestations of familial Mediterranean fever: a changing paradigm
-
Rigante D, Lopalco G, Tarantino G, Compagnone A, Fastiggi M, Cantarini L. Non-canonical manifestations of familial Mediterranean fever: a changing paradigm. Clin Rheumatol (2015) 34:1503-11. doi:10.1007/s10067-015-2916-z
-
(2015)
Clin Rheumatol
, vol.34
, pp. 1503-1511
-
-
Rigante, D.1
Lopalco, G.2
Tarantino, G.3
Compagnone, A.4
Fastiggi, M.5
Cantarini, L.6
-
165
-
-
84929842007
-
Predictors of AA amyloidosis in familial Mediterranean fever
-
Mukhin NA, Kozlovskaya LV, Bogdanova MV, Rameev VV, Moiseev SV, Simonyan AK. Predictors of AA amyloidosis in familial Mediterranean fever. Rheumatol Int (2015) 35:1257-61. doi:10.1007/s00296-014-3205-x
-
(2015)
Rheumatol Int
, vol.35
, pp. 1257-1261
-
-
Mukhin, N.A.1
Kozlovskaya, L.V.2
Bogdanova, M.V.3
Rameev, V.V.4
Moiseev, S.V.5
Simonyan, A.K.6
-
166
-
-
84873644880
-
Phenotype 2 familial Mediterranean fever: evaluation of 22 case series and review of the literature on phenotype 2 FMF
-
Altunoglu A, Erten S, Canoz MB, Yuksel A, Ceylan GG, Balci S, et al. Phenotype 2 familial Mediterranean fever: evaluation of 22 case series and review of the literature on phenotype 2 FMF. Ren Fail (2013) 35:226-30. doi:10.3109/0886022X.2012.745115
-
(2013)
Ren Fail
, vol.35
, pp. 226-230
-
-
Altunoglu, A.1
Erten, S.2
Canoz, M.B.3
Yuksel, A.4
Ceylan, G.G.5
Balci, S.6
-
167
-
-
2642568385
-
Influence of serum amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial Mediterranean fever in the Turkish population
-
Bakkaloglu A, Duzova A, Ozen S, Balci B, Besbas N, Topaloglu R, et al. Influence of serum amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial Mediterranean fever in the Turkish population. J Rheumatol (2004) 31:1139-42.
-
(2004)
J Rheumatol
, vol.31
, pp. 1139-1142
-
-
Bakkaloglu, A.1
Duzova, A.2
Ozen, S.3
Balci, B.4
Besbas, N.5
Topaloglu, R.6
-
168
-
-
0033754004
-
Identification of MEFV-independent modifying genetic factors for familial Mediterranean fever
-
Cazeneuve C, Ajrapetyan H, Papin S, Roudot-Thoraval F, Geneviève D, Mndjoyan E, et al. Identification of MEFV-independent modifying genetic factors for familial Mediterranean fever. Am J Hum Genet (2000) 67:1136-43. doi:10.1016/S0002-9297(07)62944-9
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1136-1143
-
-
Cazeneuve, C.1
Ajrapetyan, H.2
Papin, S.3
Roudot-Thoraval, F.4
Geneviève, D.5
Mndjoyan, E.6
-
169
-
-
84973620722
-
Performance of different diagnostic criteria for familial Mediterranean fever in children with periodic fevers: results from a Multicenter International Registry
-
Demirkaya E, Saglam C, Turker T, Koné-Paut I, Woo P, Doglio M, et al. Performance of different diagnostic criteria for familial Mediterranean fever in children with periodic fevers: results from a Multicenter International Registry. J Rheumatol (2016) 43:154-60. doi:10.3899/jrheum.141249
-
(2016)
J Rheumatol
, vol.43
, pp. 154-160
-
-
Demirkaya, E.1
Saglam, C.2
Turker, T.3
Koné-Paut, I.4
Woo, P.5
Doglio, M.6
-
170
-
-
0033797897
-
Breakthroughs in the genetics of hereditary fevers
-
Grateau G, Cuisset L, Dodé C, Delpech M. Breakthroughs in the genetics of hereditary fevers. Eur J Intern Med (2000) 11:242-4. doi:10.1016/S0953-6205(00)00104-7
-
(2000)
Eur J Intern Med
, vol.11
, pp. 242-244
-
-
Grateau, G.1
Cuisset, L.2
Dodé, C.3
Delpech, M.4
-
171
-
-
0343963221
-
Clinical versus genetic diagnosis of familial Mediterranean fever
-
Grateau G, Pêcheux C, Cazeneuve C, Cattan D, Dervichian M, Goossens M, et al. Clinical versus genetic diagnosis of familial Mediterranean fever. QJM (2000) 93:223-9. doi:10.1093/qjmed/93.4.223
-
(2000)
QJM
, vol.93
, pp. 223-229
-
-
Grateau, G.1
Pêcheux, C.2
Cazeneuve, C.3
Cattan, D.4
Dervichian, M.5
Goossens, M.6
-
172
-
-
84925590317
-
Evidence-based recommendations for genetic diagnosis of familial Mediterranean fever
-
Giancane G, Ter Haar NM, Wulffraat N, Vastert SJ, Barron K, Hentgen V, et al. Evidence-based recommendations for genetic diagnosis of familial Mediterranean fever. Ann Rheum Dis (2015) 74:635-41. doi:10.1136/annrheumdis-2014-206844
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 635-641
-
-
Giancane, G.1
Ter Haar, N.M.2
Wulffraat, N.3
Vastert, S.J.4
Barron, K.5
Hentgen, V.6
-
173
-
-
0035147039
-
The MICA region determines the first modifier locus in familial Mediterranean fever
-
Touitou I, Picot MC, Domingo C, Notarnicola C, Cattan D, Demaille J, et al. The MICA region determines the first modifier locus in familial Mediterranean fever. Arthritis Rheum (2001) 44:163-9. doi:10.1002/1529-0131(200101)44:1<163::AID-ANR20>3.0.CO;2-Z
-
(2001)
Arthritis Rheum
, vol.44
, pp. 163-169
-
-
Touitou, I.1
Picot, M.C.2
Domingo, C.3
Notarnicola, C.4
Cattan, D.5
Demaille, J.6
-
174
-
-
0037091012
-
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
-
Wise CA, Gillum JD, Seidman CE, Lindor NM, Veile R, Bashiardes S, et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet (2002) 11:961-9. doi:10.1093/hmg/11.8.961
-
(2002)
Hum Mol Genet
, vol.11
, pp. 961-969
-
-
Wise, C.A.1
Gillum, J.D.2
Seidman, C.E.3
Lindor, N.M.4
Veile, R.5
Bashiardes, S.6
-
175
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, et al. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc Natl Acad Sci U S A (2003) 100:13501-6. doi:10.1073/pnas.2135380100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
-
176
-
-
84862301337
-
Current status of inflammasome blockers as anti-inflammatory drugs
-
López-Castejón G, Pelegrin P. Current status of inflammasome blockers as anti-inflammatory drugs. Expert Opin Investig Drugs (2012) 21:995-1007. doi:10.1517/13543784.2012.690032
-
(2012)
Expert Opin Investig Drugs
, vol.21
, pp. 995-1007
-
-
López-Castejón, G.1
Pelegrin, P.2
-
177
-
-
0015519154
-
Colchicine for familial Mediterranean fever
-
Goldfinger SE. Colchicine for familial Mediterranean fever. N Engl J Med (1972) 287:1302. doi:10.1056/NEJM197212212872514
-
(1972)
N Engl J Med
, vol.287
, pp. 1302
-
-
Goldfinger, S.E.1
-
178
-
-
84889574819
-
Evidence-based recommendations for the practical management of familial Mediterranean fever
-
Hentgen V, Grateau G, Kone-Paut I, Livneh A, Padeh S, Rozenbaum M, et al. Evidence-based recommendations for the practical management of familial Mediterranean fever. Semin Arthritis Rheum (2013) 43:387-91. doi:10.1016/j.semarthrit.2013.04.011
-
(2013)
Semin Arthritis Rheum
, vol.43
, pp. 387-391
-
-
Hentgen, V.1
Grateau, G.2
Kone-Paut, I.3
Livneh, A.4
Padeh, S.5
Rozenbaum, M.6
-
179
-
-
0027760845
-
Colchicine in the treatment of AA and AL amyloidosis
-
Livneh A, Zemer D, Langevitz P, Shemer J, Sohar E, Pras M. Colchicine in the treatment of AA and AL amyloidosis. Semin Arthritis Rheum (1993) 23:206-14. doi:10.1016/S0049-0172(05)80042-3
-
(1993)
Semin Arthritis Rheum
, vol.23
, pp. 206-214
-
-
Livneh, A.1
Zemer, D.2
Langevitz, P.3
Shemer, J.4
Sohar, E.5
Pras, M.6
-
180
-
-
0029144844
-
Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
-
Cronstein BN, Molad Y, Reibman J, Balakhane E, Levin RI, Weissmann G. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest (1995) 96:994-1002. doi:10.1172/JCI118147
-
(1995)
J Clin Invest
, vol.96
, pp. 994-1002
-
-
Cronstein, B.N.1
Molad, Y.2
Reibman, J.3
Balakhane, E.4
Levin, R.I.5
Weissmann, G.6
-
181
-
-
0035437141
-
The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments
-
Mansfield E, Chae JJ, Komarow HD, Brotz TM, Frucht DM, Aksentijevich I, et al. The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments. Blood (2001) 98:851-9. doi:10.1182/blood.V98.3.851
-
(2001)
Blood
, vol.98
, pp. 851-859
-
-
Mansfield, E.1
Chae, J.J.2
Komarow, H.D.3
Brotz, T.M.4
Frucht, D.M.5
Aksentijevich, I.6
-
182
-
-
84868313379
-
Rilonacept for colchicine-resistant or-intolerant familial Mediterranean fever: a randomized trial
-
Hashkes PJ, Spalding SJ, Giannini EH, Huang B, Johnson A, Park G, et al. Rilonacept for colchicine-resistant or-intolerant familial Mediterranean fever: a randomized trial. Ann Intern Med (2012) 157:533-41. doi:10.7326/0003-4819-157-8-201210160-00003
-
(2012)
Ann Intern Med
, vol.157
, pp. 533-541
-
-
Hashkes, P.J.1
Spalding, S.J.2
Giannini, E.H.3
Huang, B.4
Johnson, A.5
Park, G.6
-
183
-
-
84940728830
-
Efficacy and safety of canakinumab in adolescents and adults with colchicine-resistant familial Mediterranean fever
-
Gül A, Ozdogan H, Erer B, Ugurlu S, Kasapcopur O, Davis N, et al. Efficacy and safety of canakinumab in adolescents and adults with colchicine-resistant familial Mediterranean fever. Arthritis Res Ther (2015) 17:243. doi:10.1186/s13075-015-0765-4
-
(2015)
Arthritis Res Ther
, vol.17
, pp. 243
-
-
Gül, A.1
Ozdogan, H.2
Erer, B.3
Ugurlu, S.4
Kasapcopur, O.5
Davis, N.6
-
184
-
-
79959246566
-
Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever
-
Alpay N, Sumnu A, Caliskan Y, Yazici H, Türkmen A, Gül A. Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever. Rheumatol Int (2012) 32:3277-9. doi:10.1007/s00296-010-1474-6
-
(2012)
Rheumatol Int
, vol.32
, pp. 3277-3279
-
-
Alpay, N.1
Sumnu, A.2
Caliskan, Y.3
Yazici, H.4
Türkmen, A.5
Gül, A.6
-
185
-
-
77949571201
-
Anti-IL-1 molecules: new comers and new indications
-
Moltó A, Olivé A. Anti-IL-1 molecules: new comers and new indications. Joint Bone Spine (2010) 77:102-7. doi:10.1016/j.jbspin.2009.10.011
-
(2010)
Joint Bone Spine
, vol.77
, pp. 102-107
-
-
Moltó, A.1
Olivé, A.2
-
186
-
-
33845686908
-
Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations
-
Leslie KS, Lachmann HJ, Bruning E, McGrath JA, Bybee A, Gallimore JR, et al. Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations. Arch Dermatol (2006) 142:1591-7. doi:10.1001/archderm.142.12.1591
-
(2006)
Arch Dermatol
, vol.142
, pp. 1591-1597
-
-
Leslie, K.S.1
Lachmann, H.J.2
Bruning, E.3
McGrath, J.A.4
Bybee, A.5
Gallimore, J.R.6
-
187
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, et al. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med (2006) 355:581-92. doi:10.1056/NEJMoa055137
-
(2006)
N Engl J Med
, vol.355
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Gelabert, A.4
Jones, J.5
Rubin, B.I.6
-
188
-
-
84860389029
-
On-demand anakinra treatment is effective in mevalonate kinase deficiency
-
Bodar EJ, Kuijk LM, Drenth JPH, van der Meer JWM, Simon A, Frenkel J. On-demand anakinra treatment is effective in mevalonate kinase deficiency. Ann Rheum Dis (2011) 70:2155-8. doi:10.1136/ard.2011.149922
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 2155-2158
-
-
Bodar, E.J.1
Kuijk, L.M.2
Drenth, J.P.H.3
van der Meer, J.W.M.4
Simon, A.5
Frenkel, J.6
-
189
-
-
84983108468
-
On-demand treatment with anakinra: a treatment option for selected TRAPS patients
-
Grimwood C, Despert V, Jeru I, Hentgen V. On-demand treatment with anakinra: a treatment option for selected TRAPS patients. Rheumatology (Oxford) (2015) 54:1749-51. doi:10.1093/rheumatology/kev111
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 1749-1751
-
-
Grimwood, C.1
Despert, V.2
Jeru, I.3
Hentgen, V.4
-
190
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, Leslie KS, Hachulla E, Quartier P, et al. Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med (2009) 360:2416-25. doi:10.1056/NEJMoa0810787
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
Leslie, K.S.4
Hachulla, E.5
Quartier, P.6
-
191
-
-
79957456776
-
Current status of understanding the pathogenesis and management of patients with NOMID/CINCA
-
Goldbach-Mansky R. Current status of understanding the pathogenesis and management of patients with NOMID/CINCA. Curr Rheumatol Rep (2011) 13:123-31. doi:10.1007/s11926-011-0165-y
-
(2011)
Curr Rheumatol Rep
, vol.13
, pp. 123-131
-
-
Goldbach-Mansky, R.1
-
192
-
-
84874213007
-
The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age
-
Caorsi R, Lepore L, Zulian F, Alessio M, Stabile A, Insalaco A, et al. The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age. Arthritis Res Ther (2013) 15:R33. doi:10.1186/ar4184
-
(2013)
Arthritis Res Ther
, vol.15
-
-
Caorsi, R.1
Lepore, L.2
Zulian, F.3
Alessio, M.4
Stabile, A.5
Insalaco, A.6
-
193
-
-
49449094892
-
A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome
-
Goldbach-Mansky R, Shroff SD, Wilson M, Snyder C, Plehn S, Barham B, et al. A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome. Arthritis Rheum (2008) 58:2432-42. doi:10.1002/art.23620
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2432-2442
-
-
Goldbach-Mansky, R.1
Shroff, S.D.2
Wilson, M.3
Snyder, C.4
Plehn, S.5
Barham, B.6
-
194
-
-
49449094179
-
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies
-
Hoffman HM, Throne ML, Amar NJ, Sebai M, Kivitz AJ, Kavanaugh A, et al. Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies. Arthritis Rheum (2008) 58:2443-52. doi:10.1002/art.23687
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2443-2452
-
-
Hoffman, H.M.1
Throne, M.L.2
Amar, N.J.3
Sebai, M.4
Kivitz, A.J.5
Kavanaugh, A.6
-
195
-
-
34247219224
-
(S)-1-((S)-2-([1-(4-amino-3-chloro-phenyl)-methanoyl]-amino)-3, 3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R, 3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18
-
Wannamaker W, Davies R, Namchuk M, Pollard J, Ford P, Ku G, et al. (S)-1-((S)-2-([1-(4-amino-3-chloro-phenyl)-methanoyl]-amino)-3, 3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R, 3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18. J Pharmacol Exp Ther (2007) 321:509-16. doi:10.1124/jpet.106.111344
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 509-516
-
-
Wannamaker, W.1
Davies, R.2
Namchuk, M.3
Pollard, J.4
Ford, P.5
Ku, G.6
-
196
-
-
23444439667
-
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
-
Stack JH, Beaumont K, Larsen PD, Straley KS, Henkel GW, Randle JCR, et al. IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients. J Immunol (2005) 175:2630-4. doi:10.4049/jimmunol.175.4.2630
-
(2005)
J Immunol
, vol.175
, pp. 2630-2634
-
-
Stack, J.H.1
Beaumont, K.2
Larsen, P.D.3
Straley, K.S.4
Henkel, G.W.5
Randle, J.C.R.6
-
197
-
-
84924415042
-
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
-
Coll RC, Robertson AAB, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med (2015) 21:248-55. doi:10.1038/nm.3806
-
(2015)
Nat Med
, vol.21
, pp. 248-255
-
-
Coll, R.C.1
Robertson, A.A.B.2
Chae, J.J.3
Higgins, S.C.4
Muñoz-Planillo, R.5
Inserra, M.C.6
-
198
-
-
0037930829
-
Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing
-
Laliberte RE, Perregaux DG, Hoth LR, Rosner PJ, Jordan CK, Peese KM, et al. Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing. J Biol Chem (2003) 278:16567-78. doi:10.1074/jbc.M211596200
-
(2003)
J Biol Chem
, vol.278
, pp. 16567-16578
-
-
Laliberte, R.E.1
Perregaux, D.G.2
Hoth, L.R.3
Rosner, P.J.4
Jordan, C.K.5
Peese, K.M.6
-
199
-
-
84988936950
-
Efficacy and pharmacology of the NLRP3 inflammasome inhibitor CP-456, 773 (CRID3) in murine models of dermal and pulmonary inflammation
-
Primiano MJ, Lefker BA, Bowman MR, Bree AG, Hubeau C, Bonin PD, et al. Efficacy and pharmacology of the NLRP3 inflammasome inhibitor CP-456, 773 (CRID3) in murine models of dermal and pulmonary inflammation. J Immunol (2016) 197:2421-33. doi:10.4049/jimmunol.1600035
-
(2016)
J Immunol
, vol.197
, pp. 2421-2433
-
-
Primiano, M.J.1
Lefker, B.A.2
Bowman, M.R.3
Bree, A.G.4
Hubeau, C.5
Bonin, P.D.6
-
200
-
-
84977596862
-
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice
-
Ludwig-Portugall I, Bartok E, Dhana E, Evers BDG, Primiano MJ, Hall JP, et al. An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. Kidney Int (2016). doi:10.1016/j.kint.2016.03.035
-
(2016)
Kidney Int
-
-
Ludwig-Portugall, I.1
Bartok, E.2
Dhana, E.3
Evers, B.D.G.4
Primiano, M.J.5
Hall, J.P.6
-
201
-
-
84922762977
-
Connecting two pathways through Ca2+ signaling: NLRP3 inflammasome activation induced by a hypermorphic PLCG2 mutation
-
Chae JJ, Park YH, Park C, Hwang I-Y, Hoffmann P, Kehrl JH, et al. Connecting two pathways through Ca2+ signaling: NLRP3 inflammasome activation induced by a hypermorphic PLCG2 mutation. Arthritis Rheumatol (2015) 67:563-7. doi:10.1002/art.38961
-
(2015)
Arthritis Rheumatol
, vol.67
, pp. 563-567
-
-
Chae, J.J.1
Park, Y.H.2
Park, C.3
Hwang, I.-Y.4
Hoffmann, P.5
Kehrl, J.H.6
-
202
-
-
84985992152
-
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
-
Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai WL, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A (2016) 113:10127-32. doi:10.1073/pnas.1612594113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 10127-10132
-
-
Zhou, Q.1
Yu, X.2
Demirkaya, E.3
Deuitch, N.4
Stone, D.5
Tsai, W.L.6
-
203
-
-
79955693448
-
The inflammasome in atherosclerosis and type 2 diabetes
-
Masters SL, Latz E, O'Neill LAJ. The inflammasome in atherosclerosis and type 2 diabetes. Sci Transl Med (2011) 3:81s17. doi:10.1126/scitranslmed.3001902
-
(2011)
Sci Transl Med
, vol.3
-
-
Masters, S.L.1
Latz, E.2
O'Neill, L.A.J.3
-
204
-
-
79960920271
-
NLRP3 inflammasomes link inflammation and metabolic disease
-
De Nardo D, Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol (2011) 32:373-9. doi:10.1016/j.it.2011.05.004
-
(2011)
Trends Immunol
, vol.32
, pp. 373-379
-
-
De Nardo, D.1
Latz, E.2
|