NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

Nature Immunology

Volumn 17, Issue 10, 2016, Pages 1176-1186

  Mortimer, Leanne ^a   Moreau, France ^a   MacDonald, Justin A ^a   Chadee, Kris ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CRYOPYRIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOPLASMIC RECEPTOR; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; INFLAMMASOME; PROSTAGLANDIN E RECEPTOR 4; SERINE;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CINCA SYNDROME; CONTROLLED STUDY; ENZYME INHIBITION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL LINE; GENETICS; IMMUNOLOGY; METABOLISM; MONOCYTE; MUTATION; PHENOTYPE; PHOSPHORYLATION; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL LINE; CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; HUMANS; INFLAMMASOMES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MONOCYTES; MUTATION; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PHENOTYPE; PHOSPHORYLATION; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SERINE; SIGNAL TRANSDUCTION;

EID: 84983525884     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3538     Document Type: Article

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