-
1
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
P.J. Barnes, and M. Karin Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases N. Engl. J. Med. 336 1997 1066 1071
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
2
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
A. Baroja-Mazo, F. Martín-Sánchez, A.I. Gomez, C.M. Martínez, J. Amores-Iniesta, V. Compan, M. Barberà-Cremades, J. Yagüe, E. Ruiz-Ortiz, J. Antón, and et al. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response Nat. Immunol. 15 2014 738 748
-
(2014)
Nat. Immunol.
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martín-Sánchez, F.2
Gomez, A.I.3
Martínez, C.M.4
Amores-Iniesta, J.5
Compan, V.6
Barberà-Cremades, M.7
Yagüe, J.8
Ruiz-Ortiz, E.9
Antón, J.10
-
4
-
-
84887430028
-
Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies
-
S.D. Brydges, L. Broderick, M.D. McGeough, C.A. Pena, J.L. Mueller, and H.M. Hoffman Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies J. Clin. Invest. 123 2013 4695 4705
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 4695-4705
-
-
Brydges, S.D.1
Broderick, L.2
McGeough, M.D.3
Pena, C.A.4
Mueller, J.L.5
Hoffman, H.M.6
-
5
-
-
33745620439
-
Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress
-
B.V. Chernyak, D.S. Izyumov, K.G. Lyamzaev, A.A. Pashkovskaya, O.Y. Pletjushkina, Y.N. Antonenko, D.V. Sakharov, K.W. Wirtz, and V.P. Skulachev Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress Biochim. Biophys. Acta 1757 2006 525 534
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 525-534
-
-
Chernyak, B.V.1
Izyumov, D.S.2
Lyamzaev, K.G.3
Pashkovskaya, A.A.4
Pletjushkina, O.Y.5
Antonenko, Y.N.6
Sakharov, D.V.7
Wirtz, K.W.8
Skulachev, V.P.9
-
6
-
-
57949087452
-
Molecular inflammation: Underpinnings of aging and age-related diseases
-
H.Y. Chung, M. Cesari, S. Anton, E. Marzetti, S. Giovannini, A.Y. Seo, C. Carter, B.P. Yu, and C. Leeuwenburgh Molecular inflammation: underpinnings of aging and age-related diseases Ageing Res. Rev. 8 2009 18 30
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 18-30
-
-
Chung, H.Y.1
Cesari, M.2
Anton, S.3
Marzetti, E.4
Giovannini, S.5
Seo, A.Y.6
Carter, C.7
Yu, B.P.8
Leeuwenburgh, C.9
-
7
-
-
76349090912
-
The IKK complex contributes to the induction of autophagy
-
A. Criollo, L. Senovilla, H. Authier, M.C. Maiuri, E. Morselli, I. Vitale, O. Kepp, E. Tasdemir, L. Galluzzi, S. Shen, and et al. The IKK complex contributes to the induction of autophagy EMBO J. 29 2010 619 631
-
(2010)
EMBO J.
, vol.29
, pp. 619-631
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
Kepp, O.7
Tasdemir, E.8
Galluzzi, L.9
Shen, S.10
-
8
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
S.C. Eisenbarth, O.R. Colegio, W. O'Connor, F.S. Sutterwala, and R.A. Flavell Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants Nature 453 2008 1122 1126
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
9
-
-
84922776083
-
PINK1/Parkin-mediated mitophagy in mammalian cells
-
A. Eiyama, and K. Okamoto PINK1/Parkin-mediated mitophagy in mammalian cells Curr. Opin. Cell Biol. 33 2015 95 101
-
(2015)
Curr. Opin. Cell Biol.
, vol.33
, pp. 95-101
-
-
Eiyama, A.1
Okamoto, K.2
-
10
-
-
84927724336
-
Initiation and perpetuation of NLRP3 inflammasome activation and assembly
-
E.I. Elliott, and F.S. Sutterwala Initiation and perpetuation of NLRP3 inflammasome activation and assembly Immunol. Rev. 265 2015 35 52
-
(2015)
Immunol. Rev.
, vol.265
, pp. 35-52
-
-
Elliott, E.I.1
Sutterwala, F.S.2
-
11
-
-
84904692363
-
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
-
B.S. Franklin, L. Bossaller, D. De Nardo, J.M. Ratter, A. Stutz, G. Engels, C. Brenker, M. Nordhoff, S.R. Mirandola, A. Al-Amoudi, and et al. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation Nat. Immunol. 15 2014 727 737
-
(2014)
Nat. Immunol.
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
Brenker, C.7
Nordhoff, M.8
Mirandola, S.R.9
Al-Amoudi, A.10
-
12
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
S. Geisler, K.M. Holmström, D. Skujat, F.C. Fiesel, O.C. Rothfuss, P.J. Kahle, and W. Springer PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 Nat. Cell Biol. 12 2010 119 131
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
13
-
-
34548225362
-
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta
-
F.R. Greten, M.C. Arkan, J. Bollrath, L.C. Hsu, J. Goode, C. Miething, S.I. Göktuna, M. Neuenhahn, J. Fierer, S. Paxian, and et al. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta Cell 130 2007 918 931
-
(2007)
Cell
, vol.130
, pp. 918-931
-
-
Greten, F.R.1
Arkan, M.C.2
Bollrath, J.3
Hsu, L.C.4
Goode, J.5
Miething, C.6
Göktuna, S.I.7
Neuenhahn, M.8
Fierer, J.9
Paxian, S.10
-
14
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
J. Henao-Mejia, E. Elinav, C. Jin, L. Hao, W.Z. Mehal, T. Strowig, C.A. Thaiss, A.L. Kau, S.C. Eisenbarth, M.J. Jurczak, and et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity Nature 482 2012 179 185
-
(2012)
Nature
, vol.482
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
Thaiss, C.A.7
Kau, A.L.8
Eisenbarth, S.C.9
Jurczak, M.J.10
-
15
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, K.L. Rock, K.A. Fitzgerald, and E. Latz Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Nat. Immunol. 9 2008 847 856
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
16
-
-
78751628117
-
IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ
-
L.C. Hsu, T. Enzler, J. Seita, A.M. Timmer, C.Y. Lee, T.Y. Lai, G.Y. Yu, L.C. Lai, V. Temkin, U. Sinzig, and et al. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ Nat. Immunol. 12 2011 144 150
-
(2011)
Nat. Immunol.
, vol.12
, pp. 144-150
-
-
Hsu, L.C.1
Enzler, T.2
Seita, J.3
Timmer, A.M.4
Lee, C.Y.5
Lai, T.Y.6
Yu, G.Y.7
Lai, L.C.8
Temkin, V.9
Sinzig, U.10
-
17
-
-
84884474591
-
NLRP3 inflammasome activation in D-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1
-
S.J. Kim, and S.M. Lee NLRP3 inflammasome activation in D-galactosamine and lipopolysaccharide-induced acute liver failure: role of heme oxygenase-1 Free Radic. Biol. Med. 65 2013 997 1004
-
(2013)
Free Radic. Biol. Med.
, vol.65
, pp. 997-1004
-
-
Kim, S.J.1
Lee, S.M.2
-
18
-
-
61449168881
-
The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity
-
J.Y. Kim, and K. Ozato The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity J. Immunol. 182 2009 2131 2140
-
(2009)
J. Immunol.
, vol.182
, pp. 2131-2140
-
-
Kim, J.Y.1
Ozato, K.2
-
19
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
M. Komatsu, S. Waguri, T. Ueno, J. Iwata, S. Murata, I. Tanida, J. Ezaki, N. Mizushima, Y. Ohsumi, Y. Uchiyama, and et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice J. Cell Biol. 169 2005 425 434
-
(2005)
J. Cell Biol.
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
-
20
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
M. Komatsu, S. Waguri, M. Koike, Y.S. Sou, T. Ueno, T. Hara, N. Mizushima, J. Iwata, J. Ezaki, S. Murata, and et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice Cell 131 2007 1149 1163
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
-
22
-
-
84923357083
-
Homeostasis, inflammation, and disease susceptibility
-
M.E. Kotas, and R. Medzhitov Homeostasis, inflammation, and disease susceptibility Cell 160 2015 816 827
-
(2015)
Cell
, vol.160
, pp. 816-827
-
-
Kotas, M.E.1
Medzhitov, R.2
-
23
-
-
84869504451
-
Inflammasomes and their roles in health and disease
-
M. Lamkanfi, and V.M. Dixit Inflammasomes and their roles in health and disease Annu. Rev. Cell Dev. Biol. 28 2012 137 161
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 137-161
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
24
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
M. Lamkanfi, and V.M. Dixit Mechanisms and functions of inflammasomes Cell 157 2014 1013 1022
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
25
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
M. Lazarou, D.A. Sliter, L.A. Kane, S.A. Sarraf, C. Wang, J.L. Burman, D.P. Sideris, A.I. Fogel, and R.J. Youle The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy Nature 524 2015 309 314
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D.A.2
Kane, L.A.3
Sarraf, S.A.4
Wang, C.5
Burman, J.L.6
Sideris, D.P.7
Fogel, A.I.8
Youle, R.J.9
-
26
-
-
84876789628
-
Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice
-
N. Li, X. Wu, R.G. Holzer, J.H. Lee, J. Todoric, E.J. Park, H. Ogata, A.S. Gukovskaya, I. Gukovsky, D.P. Pizzo, and et al. Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice J. Clin. Invest. 123 2013 2231 2243
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 2231-2243
-
-
Li, N.1
Wu, X.2
Holzer, R.G.3
Lee, J.H.4
Todoric, J.5
Park, E.J.6
Ogata, H.7
Gukovskaya, A.S.8
Gukovsky, I.9
Pizzo, D.P.10
-
27
-
-
33845222777
-
Innate immunity and inflammation in ageing: A key for understanding age-related diseases
-
F. Licastro, G. Candore, D. Lio, E. Porcellini, G. Colonna-Romano, C. Franceschi, and C. Caruso Innate immunity and inflammation in ageing: a key for understanding age-related diseases Immun. Ageing 2 2005 8
-
(2005)
Immun. Ageing
, vol.2
, pp. 8
-
-
Licastro, F.1
Candore, G.2
Lio, D.3
Porcellini, E.4
Colonna-Romano, G.5
Franceschi, C.6
Caruso, C.7
-
28
-
-
84908356704
-
Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response
-
T. Liu, Y. Yamaguchi, Y. Shirasaki, K. Shikada, M. Yamagishi, K. Hoshino, T. Kaisho, K. Takemoto, T. Suzuki, E. Kuranaga, and et al. Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response Cell Rep. 8 2014 974 982
-
(2014)
Cell Rep.
, vol.8
, pp. 974-982
-
-
Liu, T.1
Yamaguchi, Y.2
Shirasaki, Y.3
Shikada, K.4
Yamagishi, M.5
Hoshino, K.6
Kaisho, T.7
Takemoto, K.8
Suzuki, T.9
Kuranaga, E.10
-
29
-
-
84896332642
-
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
-
A. Lu, V.G. Magupalli, J. Ruan, Q. Yin, M.K. Atianand, M.R. Vos, G.F. Schröder, K.A. Fitzgerald, H. Wu, and E.H. Egelman Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes Cell 156 2014 1193 1206
-
(2014)
Cell
, vol.156
, pp. 1193-1206
-
-
Lu, A.1
Magupalli, V.G.2
Ruan, J.3
Yin, Q.4
Atianand, M.K.5
Vos, M.R.6
Schröder, G.F.7
Fitzgerald, K.A.8
Wu, H.9
Egelman, E.H.10
-
30
-
-
84885576570
-
The ubiquitin ligase parkin mediates resistance to intracellular pathogens
-
P.S. Manzanillo, J.S. Ayres, R.O. Watson, A.C. Collins, G. Souza, C.S. Rae, D.S. Schneider, K. Nakamura, M.U. Shiloh, and J.S. Cox The ubiquitin ligase parkin mediates resistance to intracellular pathogens Nature 501 2013 512 516
-
(2013)
Nature
, vol.501
, pp. 512-516
-
-
Manzanillo, P.S.1
Ayres, J.S.2
Watson, R.O.3
Collins, A.C.4
Souza, G.5
Rae, C.S.6
Schneider, D.S.7
Nakamura, K.8
Shiloh, M.U.9
Cox, J.S.10
-
31
-
-
47949099098
-
Origin and physiological roles of inflammation
-
R. Medzhitov Origin and physiological roles of inflammation Nature 454 2008 428 435
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
32
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
E. Meylan, J. Tschopp, and M. Karin Intracellular pattern recognition receptors in the host response Nature 442 2006 39 44
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
33
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
E.A. Miao, I.A. Leaf, P.M. Treuting, D.P. Mao, M. Dors, A. Sarkar, S.E. Warren, M.D. Wewers, and A. Aderem Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria Nat. Immunol. 11 2010 1136 1142
-
(2010)
Nat. Immunol.
, vol.11
, pp. 1136-1142
-
-
Miao, E.A.1
Leaf, I.A.2
Treuting, P.M.3
Mao, D.P.4
Dors, M.5
Sarkar, A.6
Warren, S.E.7
Wewers, M.D.8
Aderem, A.9
-
34
-
-
66449114033
-
P62 at the crossroads of autophagy, apoptosis, and cancer
-
J. Moscat, and M.T. Diaz-Meco p62 at the crossroads of autophagy, apoptosis, and cancer Cell 137 2009 1001 1004
-
(2009)
Cell
, vol.137
, pp. 1001-1004
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
35
-
-
84873842067
-
P62 links β-adrenergic input to mitochondrial function and thermogenesis
-
T.D. Müller, S.J. Lee, M. Jastroch, D. Kabra, K. Stemmer, M. Aichler, B. Abplanalp, G. Ananthakrishnan, N. Bhardwaj, S. Collins, and et al. p62 links β-adrenergic input to mitochondrial function and thermogenesis J. Clin. Invest. 123 2013 469 478
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 469-478
-
-
Müller, T.D.1
Lee, S.J.2
Jastroch, M.3
Kabra, D.4
Stemmer, K.5
Aichler, M.6
Abplanalp, B.7
Ananthakrishnan, G.8
Bhardwaj, N.9
Collins, S.10
-
36
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
K. Nakahira, J.A. Haspel, V.A. Rathinam, S.J. Lee, T. Dolinay, H.C. Lam, J.A. Englert, M. Rabinovitch, M. Cernadas, H.P. Kim, and et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Nat. Immunol. 12 2011 222 230
-
(2011)
Nat. Immunol.
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
-
37
-
-
78649300971
-
P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
D. Narendra, L.A. Kane, D.N. Hauser, I.M. Fearnley, and R.J. Youle p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy 6 2010 1090 1106
-
(2010)
Autophagy
, vol.6
, pp. 1090-1106
-
-
Narendra, D.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
38
-
-
77954695260
-
P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
-
K. Okatsu, K. Saisho, M. Shimanuki, K. Nakada, H. Shitara, Y.S. Sou, M. Kimura, S. Sato, N. Hattori, M. Komatsu, and et al. p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria Genes Cells 15 2010 887 900
-
(2010)
Genes Cells
, vol.15
, pp. 887-900
-
-
Okatsu, K.1
Saisho, K.2
Shimanuki, M.3
Nakada, K.4
Shitara, H.5
Sou, Y.S.6
Kimura, M.7
Sato, S.8
Hattori, N.9
Komatsu, M.10
-
39
-
-
84921369563
-
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease
-
A.M. Pickrell, and R.J. Youle The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease Neuron 85 2015 257 273
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
40
-
-
33644629034
-
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62
-
A. Rodriguez, A. Durán, M. Selloum, M.F. Champy, F.J. Diez-Guerra, J.M. Flores, M. Serrano, J. Auwerx, M.T. Diaz-Meco, and J. Moscat Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62 Cell Metab. 3 2006 211 222
-
(2006)
Cell Metab.
, vol.3
, pp. 211-222
-
-
Rodriguez, A.1
Durán, A.2
Selloum, M.3
Champy, M.F.4
Diez-Guerra, F.J.5
Flores, J.M.6
Serrano, M.7
Auwerx, J.8
Diaz-Meco, M.T.9
Moscat, J.10
-
41
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
T. Saitoh, N. Fujita, M.H. Jang, S. Uematsu, B.G. Yang, T. Satoh, H. Omori, T. Noda, N. Yamamoto, M. Komatsu, and et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production Nature 456 2008 264 268
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
-
42
-
-
77950362382
-
The inflammasomes
-
K. Schroder, and J. Tschopp The inflammasomes Cell 140 2010 821 832
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
43
-
-
84923482955
-
Hepatic inflammation and fibrosis: Functional links and key pathways
-
E. Seki, and R.F. Schwabe Hepatic inflammation and fibrosis: functional links and key pathways Hepatology 61 2015 1066 1079
-
(2015)
Hepatology
, vol.61
, pp. 1066-1079
-
-
Seki, E.1
Schwabe, R.F.2
-
44
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
-
C.S. Shi, K. Shenderov, N.N. Huang, J. Kabat, M. Abu-Asab, K.A. Fitzgerald, A. Sher, and J.H. Kehrl Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction Nat. Immunol. 13 2012 255 263
-
(2012)
Nat. Immunol.
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
45
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
K. Shimada, T.R. Crother, J. Karlin, J. Dagvadorj, N. Chiba, S. Chen, V.K. Ramanujan, A.J. Wolf, L. Vergnes, D.M. Ojcius, and et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis Immunity 36 2012 401 414
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
-
46
-
-
34548817868
-
In vitro production of Mallory bodies and intracellular hyaline bodies: The central role of sequestosome 1/p62
-
C. Stumptner, A. Fuchsbichler, K. Zatloukal, and H. Denk In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62 Hepatology 46 2007 851 860
-
(2007)
Hepatology
, vol.46
, pp. 851-860
-
-
Stumptner, C.1
Fuchsbichler, A.2
Zatloukal, K.3
Denk, H.4
-
47
-
-
84924328294
-
A gp130-Src-YAP module links inflammation to epithelial regeneration
-
K. Taniguchi, L.W. Wu, S.I. Grivennikov, P.R. de Jong, I. Lian, F.X. Yu, K. Wang, S.B. Ho, B.S. Boland, J.T. Chang, and et al. A gp130-Src-YAP module links inflammation to epithelial regeneration Nature 519 2015 57 62
-
(2015)
Nature
, vol.519
, pp. 57-62
-
-
Taniguchi, K.1
Wu, L.W.2
Grivennikov, S.I.3
De Jong, P.R.4
Lian, I.5
Yu, F.X.6
Wang, K.7
Ho, S.B.8
Boland, B.S.9
Chang, J.T.10
-
48
-
-
84860883878
-
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
-
V. Tarallo, Y. Hirano, B.D. Gelfand, S. Dridi, N. Kerur, Y. Kim, W.G. Cho, H. Kaneko, B.J. Fowler, S. Bogdanovich, and et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Cell 149 2012 847 859
-
(2012)
Cell
, vol.149
, pp. 847-859
-
-
Tarallo, V.1
Hirano, Y.2
Gelfand, B.D.3
Dridi, S.4
Kerur, N.5
Kim, Y.6
Cho, W.G.7
Kaneko, H.8
Fowler, B.J.9
Bogdanovich, S.10
-
49
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
S. Vallabhapurapu, and M. Karin Regulation and function of NF-kappaB transcription factors in the immune system Annu. Rev. Immunol. 27 2009 693 733
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
50
-
-
84921498910
-
The NAIP/NLRC4 inflammasomes
-
R.E. Vance The NAIP/NLRC4 inflammasomes Curr. Opin. Immunol. 32 2015 84 89
-
(2015)
Curr. Opin. Immunol.
, vol.32
, pp. 84-89
-
-
Vance, R.E.1
-
51
-
-
84875542536
-
Recognition of bacteria by inflammasomes
-
J. von Moltke, J.S. Ayres, E.M. Kofoed, J. Chavarría-Smith, and R.E. Vance Recognition of bacteria by inflammasomes Annu. Rev. Immunol. 31 2013 73 106
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 73-106
-
-
Von Moltke, J.1
Ayres, J.S.2
Kofoed, E.M.3
Chavarría-Smith, J.4
Vance, R.E.5
-
52
-
-
34848868424
-
Bacterial endotoxin: A trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model
-
A. Vonlaufen, Z. Xu, B. Daniel, R.K. Kumar, R. Pirola, J. Wilson, and M.V. Apte Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model Gastroenterology 133 2007 1293 1303
-
(2007)
Gastroenterology
, vol.133
, pp. 1293-1303
-
-
Vonlaufen, A.1
Xu, Z.2
Daniel, B.3
Kumar, R.K.4
Pirola, R.5
Wilson, J.6
Apte, M.V.7
-
53
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
D.C. Wallace A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine Annu. Rev. Genet. 39 2005 359 407
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
54
-
-
84908544666
-
Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy
-
J. Yu, H. Nagasu, T. Murakami, H. Hoang, L. Broderick, H.M. Hoffman, and T. Horng Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy Proc. Natl. Acad. Sci. USA 111 2014 15514 15519
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 15514-15519
-
-
Yu, J.1
Nagasu, H.2
Murakami, T.3
Hoang, H.4
Broderick, L.5
Hoffman, H.M.6
Horng, T.7
-
55
-
-
84875908991
-
TRPM2 links oxidative stress to NLRP3 inflammasome activation
-
Z. Zhong, Y. Zhai, S. Liang, Y. Mori, R. Han, F.S. Sutterwala, and L. Qiao TRPM2 links oxidative stress to NLRP3 inflammasome activation Nat. Commun. 4 2013 1611
-
(2013)
Nat. Commun.
, vol.4
, pp. 1611
-
-
Zhong, Z.1
Zhai, Y.2
Liang, S.3
Mori, Y.4
Han, R.5
Sutterwala, F.S.6
Qiao, L.7
-
56
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
R. Zhou, A.S. Yazdi, P. Menu, and J. Tschopp A role for mitochondria in NLRP3 inflammasome activation Nature 469 2011 221 225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|