메뉴 건너뛰기




Volumn 194, Issue 8, 2015, Pages 3937-3952

K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CALCIUM SENSING RECEPTOR; CRYOPYRIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; ION TRANSPORT AFFECTING AGENT; NIGERICIN; POTASSIUM ION EFFLUX AGONIST; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; UNCLASSIFIED DRUG; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; 2-AMINOETHOXYDIPHENYL BORATE; ADENOSINE TRIPHOSPHATE; BORON DERIVATIVE; CARRIER PROTEIN; CHELATING AGENT; CIAS1 PROTEIN, MOUSE; DIPEPTIDE; EGTAZIC ACID; IL1B PROTEIN, MOUSE; IMMUNOSUPPRESSIVE AGENT; INFLAMMASOME; IONOPHORE; LEUCYL-LEUCINE-METHYL ESTER; POTASSIUM;

EID: 84927669849     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402658     Document Type: Article
Times cited : (223)

References (62)
  • 1
    • 0012529116 scopus 로고    scopus 로고
    • The inflammatory response
    • 8th Ed. K. Kaushansky, M. A. Lichtman, U. Seiligson, E. Beutler, T. J. Kipps, and J. T. Prchal, eds. McGraw-Hill, New York
    • Warren, J. S., and P. A. Ward. 2010. The inflammatory response. In Williams Hematology, 8th Ed. K. Kaushansky, M. A. Lichtman, U. Seiligson, E. Beutler, T. J. Kipps, and J. T. Prchal, eds. McGraw-Hill, New York. p. 251-260.
    • (2010) Williams Hematology , pp. 251-260
    • Warren, J.S.1    Ward, P.A.2
  • 2
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder, K., and J. Tschopp. 2010. The inflammasomes. Cell 140:821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 5
    • 84896381627 scopus 로고    scopus 로고
    • Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation
    • Cai, X., J. Chen, H. Xu, S. Liu, Q. X. Jiang, R. Halfmann, and Z. J. Chen. 2014. Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation. Cell 156:1207-1222.
    • (2014) Cell , vol.156 , pp. 1207-1222
    • Cai, X.1    Chen, J.2    Xu, H.3    Liu, S.4    Jiang, Q.X.5    Halfmann, R.6    Chen, Z.J.7
  • 6
    • 84881542521 scopus 로고    scopus 로고
    • Inflammasomemediated pyroptotic and apoptotic cell death, and defense against infection
    • Aachoui, Y., V. Sagulenko, E. A. Miao, and K. J. Stacey. 2013. Inflammasomemediated pyroptotic and apoptotic cell death, and defense against infection. Curr. Opin. Microbiol. 16:319-326.
    • (2013) Curr. Opin. Microbiol. , vol.16 , pp. 319-326
    • Aachoui, Y.1    Sagulenko, V.2    Miao, E.A.3    Stacey, K.J.4
  • 8
    • 70349334298 scopus 로고    scopus 로고
    • A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
    • Muñoz-Planillo, R., L. Franchi, L. S. Miller, and G. Núñez. 2009. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Immunol. 183:3942-3948.
    • (2009) J. Immunol. , vol.183 , pp. 3942-3948
    • Muñoz-Planillo, R.1    Franchi, L.2    Miller, L.S.3    Núñez, G.4
  • 9
    • 0028175838 scopus 로고
    • Interleukin-1b maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
    • Perregaux, D., and C. A. Gabel. 1994. Interleukin-1b maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269:15195-15203.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15195-15203
    • Perregaux, D.1    Gabel, C.A.2
  • 12
    • 84939889550 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation and interleukin-1b release in macrophages require calcium but are independent of calcium-activated NADPH oxidases
    • Rada, B., J. J. Park, P. Sil, M. Geiszt, and T. L. Leto. 2014. NLRP3 inflammasome activation and interleukin-1b release in macrophages require calcium but are independent of calcium-activated NADPH oxidases. Inflamm. Res. 63:821-830.
    • (2014) Inflamm. Res. , vol.63 , pp. 821-830
    • Rada, B.1    Park, J.J.2    Sil, P.3    Geiszt, M.4    Leto, T.L.5
  • 17
    • 66849095952 scopus 로고    scopus 로고
    • Microtubule disruption with BAPTA and dimethyl BAPTA by a calcium chelationindependent mechanism in 3T3-L1 adipocytes
    • Furuta, A., M. Tanaka, W. Omata, M. Nagasawa, I. Kojima, and H. Shibata. 2009. Microtubule disruption with BAPTA and dimethyl BAPTA by a calcium chelationindependent mechanism in 3T3-L1 adipocytes. Endocr. J. 56:235-243.
    • (2009) Endocr. J. , vol.56 , pp. 235-243
    • Furuta, A.1    Tanaka, M.2    Omata, W.3    Nagasawa, M.4    Kojima, I.5    Shibata, H.6
  • 18
    • 50049109456 scopus 로고    scopus 로고
    • Non-selective cation channel blockers: Potential use in nervous system basic research and therapeutics
    • Peña, F., and B. Ordaz. 2008. Non-selective cation channel blockers: potential use in nervous system basic research and therapeutics. Mini Rev. Med. Chem. 8:812-819.
    • (2008) Mini Rev. Med. Chem. , vol.8 , pp. 812-819
    • Peña, F.1    Ordaz, B.2
  • 20
    • 0017102422 scopus 로고
    • Biological applications of ionophores
    • Pressman, B. C. 1976. Biological applications of ionophores. Annu. Rev. Biochem. 45:501-530.
    • (1976) Annu. Rev. Biochem. , vol.45 , pp. 501-530
    • Pressman, B.C.1
  • 22
    • 65249164404 scopus 로고    scopus 로고
    • P2X7 receptor-stimulated secretion of MHC class IIcontaining exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1
    • Qu, Y., L. Ramachandra, S. Mohr, L. Franchi, C. V. Harding, G. Nunez, and G. R. Dubyak. 2009. P2X7 receptor-stimulated secretion of MHC class IIcontaining exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1. J. Immunol. 182:5052-5062.
    • (2009) J. Immunol. , vol.182 , pp. 5052-5062
    • Qu, Y.1    Ramachandra, L.2    Mohr, S.3    Franchi, L.4    Harding, C.V.5    Nunez, G.6    Dubyak, G.R.7
  • 24
    • 84885966098 scopus 로고    scopus 로고
    • Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1b via caspase-8 in dendritic cells
    • Antonopoulos, C., C. El Sanadi, W. J. Kaiser, E. S. Mocarski, and G. R. Dubyak. 2013. Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1b via caspase-8 in dendritic cells. J. Immunol. 191:4789-4803.
    • (2013) J. Immunol. , vol.191 , pp. 4789-4803
    • Antonopoulos, C.1    El Sanadi, C.2    Kaiser, W.J.3    Mocarski, E.S.4    Dubyak, G.R.5
  • 25
    • 33749576792 scopus 로고    scopus 로고
    • Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
    • Fink, S. L., and B. T. Cookson. 2006. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell. Microbiol. 8:1812-1825.
    • (2006) Cell. Microbiol. , vol.8 , pp. 1812-1825
    • Fink, S.L.1    Cookson, B.T.2
  • 26
    • 41949127121 scopus 로고    scopus 로고
    • Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
    • Fink, S. L., T. Bergsbaken, and B. T. Cookson. 2008. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc. Natl. Acad. Sci. USA 105:4312-4317.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4312-4317
    • Fink, S.L.1    Bergsbaken, T.2    Cookson, B.T.3
  • 30
    • 0025374741 scopus 로고
    • The action of leucyl-leucine methyl ester on cytotoxic lymphocytes requires uptake by a novel dipeptide-specific facilitated transport system and dipeptidyl peptidase I-mediated conversion to membranolytic products
    • Thiele, D. L., and P. E. Lipsky. 1990. The action of leucyl-leucine methyl ester on cytotoxic lymphocytes requires uptake by a novel dipeptide-specific facilitated transport system and dipeptidyl peptidase I-mediated conversion to membranolytic products. J. Exp. Med. 172:183-194.
    • (1990) J. Exp. Med. , vol.172 , pp. 183-194
    • Thiele, D.L.1    Lipsky, P.E.2
  • 32
    • 84901601733 scopus 로고    scopus 로고
    • Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome
    • Horng, T. 2014. Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome. Trends Immunol. 35:253-261.
    • (2014) Trends Immunol. , vol.35 , pp. 253-261
    • Horng, T.1
  • 34
    • 84880762970 scopus 로고    scopus 로고
    • Store-operated Orai channels: Structure and function
    • Prakriya, M. 2013. Store-operated Orai channels: structure and function. Curr. Top. Membr. 71:1-32.
    • (2013) Curr. Top. Membr. , vol.71 , pp. 1-32
    • Prakriya, M.1
  • 37
    • 0018076070 scopus 로고
    • Characterization of ionomycin as a calcium ionophore
    • Liu, C., and T. E. Hermann. 1978. Characterization of ionomycin as a calcium ionophore. J. Biol. Chem. 253:5892-5894.
    • (1978) J. Biol. Chem. , vol.253 , pp. 5892-5894
    • Liu, C.1    Hermann, T.E.2
  • 38
    • 33745357465 scopus 로고    scopus 로고
    • Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-59-nucleotidase in myeloid leukocytes
    • Clifford, E. E., K. A. Martin, P. Dalal, R. Thomas, and G. R. Dubyak. 1997. Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-59-nucleotidase in myeloid leukocytes. Am. J. Physiol. 273:C973-C987.
    • (1997) Am. J. Physiol. , vol.273 , pp. C973-C987
    • Clifford, E.E.1    Martin, K.A.2    Dalal, P.3    Thomas, R.4    Dubyak, G.R.5
  • 39
    • 84879845082 scopus 로고    scopus 로고
    • Molecular biology for formyl peptide receptors in human diseases
    • Li, Y., and D. Ye. 2013. Molecular biology for formyl peptide receptors in human diseases. J. Mol. Med. 91:781-789.
    • (2013) J. Mol. Med. , vol.91 , pp. 781-789
    • Li, Y.1    Ye, D.2
  • 40
    • 0042242912 scopus 로고    scopus 로고
    • 2+ in regulation of IL-1b secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
    • 2+ in regulation of IL-1b secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am. J. Physiol. Cell Physiol. 285:C286-C299.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285 , pp. C286-C299
    • Gudipaty, L.1    Munetz, J.2    Verhoef, P.A.3    Dubyak, G.R.4
  • 41
    • 34548614009 scopus 로고    scopus 로고
    • Nonclassical IL-1b secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
    • Qu, Y., L. Franchi, G. Nunez, and G. R. Dubyak. 2007. Nonclassical IL-1b secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 179:1913-1925.
    • (2007) J. Immunol. , vol.179 , pp. 1913-1925
    • Qu, Y.1    Franchi, L.2    Nunez, G.3    Dubyak, G.R.4
  • 42
    • 84867652682 scopus 로고    scopus 로고
    • P2X7 receptor regulation of non-classical secretion from immune effector cells
    • Dubyak, G. R. 2012. P2X7 receptor regulation of non-classical secretion from immune effector cells. Cell. Microbiol. 14:1697-1706.
    • (2012) Cell. Microbiol. , vol.14 , pp. 1697-1706
    • Dubyak, G.R.1
  • 44
    • 0025721122 scopus 로고
    • Evidence that UTP and ATP regulate phospholipase C through a common extracellular 59-nucleotide receptor in human airway epithelial cells
    • Brown, H. A., E. R. Lazarowski, R. C. Boucher, and T. K. Harden. 1991. Evidence that UTP and ATP regulate phospholipase C through a common extracellular 59-nucleotide receptor in human airway epithelial cells. Mol. Pharmacol. 40:648-655.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 648-655
    • Brown, H.A.1    Lazarowski, E.R.2    Boucher, R.C.3    Harden, T.K.4
  • 45
    • 85027946178 scopus 로고    scopus 로고
    • Calcium-sensing receptor (CaSR): Pharmacological properties and signaling pathways
    • Conigrave, A. D., and D. T. Ward. 2013. Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways. Best Pract. Res. Clin. Endocrinol. Metab. 27:315-331.
    • (2013) Best Pract. Res. Clin. Endocrinol. Metab. , vol.27 , pp. 315-331
    • Conigrave, A.D.1    Ward, D.T.2
  • 46
    • 84857701450 scopus 로고    scopus 로고
    • 2+-regulated ion channels
    • 2+-regulated ion channels. BMB Rep 44:635-646.
    • (2011) BMB Rep , vol.44 , pp. 635-646
    • Cox, D.H.1
  • 48
    • 84867770402 scopus 로고    scopus 로고
    • Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
    • Juliana, C., T. Fernandes-Alnemri, S. Kang, A. Farias, F. Qin, and E. S. Alnemri. 2012. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J. Biol. Chem. 287:36617-36622.
    • (2012) J. Biol. Chem. , vol.287 , pp. 36617-36622
    • Juliana, C.1    Fernandes-Alnemri, T.2    Kang, S.3    Farias, A.4    Qin, F.5    Alnemri, E.S.6
  • 50
    • 84872782298 scopus 로고    scopus 로고
    • Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
    • Py, B. F., M. S. Kim, H. Vakifahmetoglu-Norberg, and J. Yuan. 2013. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol. Cell 49:331-338.
    • (2013) Mol. Cell , vol.49 , pp. 331-338
    • Py, B.F.1    Kim, M.S.2    Vakifahmetoglu-Norberg, H.3    Yuan, J.4
  • 52
    • 84870481575 scopus 로고    scopus 로고
    • Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation
    • Xiong, Y., X. P. Jing, X. W. Zhou, X. L. Wang, Y. Yang, X. Y. Sun, M. Qiu, F. Y. Cao, Y. M. Lu, R. Liu, and J. Z. Wang. 2013. Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation. Neurobiol. Aging 34:745-756.
    • (2013) Neurobiol. Aging , vol.34 , pp. 745-756
    • Xiong, Y.1    Jing, X.P.2    Zhou, X.W.3    Wang, X.L.4    Yang, Y.5    Sun, X.Y.6    Qiu, M.7    Cao, F.Y.8    Lu, Y.M.9    Liu, R.10    Wang, J.Z.11
  • 53
    • 84876567161 scopus 로고    scopus 로고
    • Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
    • Misawa, T., M. Takahama, T. Kozaki, H. Lee, J. Zou, T. Saitoh, and S. Akira. 2013. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat. Immunol. 14:454-460.
    • (2013) Nat. Immunol. , vol.14 , pp. 454-460
    • Misawa, T.1    Takahama, M.2    Kozaki, T.3    Lee, H.4    Zou, J.5    Saitoh, T.6    Akira, S.7
  • 54
    • 47249095816 scopus 로고    scopus 로고
    • 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels
    • Peinelt, C., A. Lis, A. Beck, A. Fleig, and R. Penner. 2008. 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. J. Physiol. 586:3061-3073.
    • (2008) J. Physiol. , vol.586 , pp. 3061-3073
    • Peinelt, C.1    Lis, A.2    Beck, A.3    Fleig, A.4    Penner, R.5
  • 56
    • 50349103128 scopus 로고    scopus 로고
    • Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry
    • DeHaven, W. I., J. T. Smyth, R. R. Boyles, G. S. Bird, and J. W. Putney, Jr. 2008. Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry. J. Biol. Chem. 283:19265-19273.
    • (2008) J. Biol. Chem. , vol.283 , pp. 19265-19273
    • De Haven, W.I.1    Smyth, J.T.2    Boyles, R.R.3    Bird, G.S.4    Putney, J.W.J.5
  • 59
    • 84899534640 scopus 로고    scopus 로고
    • State-dependent block of Orai3 TM1 and TM3 cysteine mutants: Insights into 2-APB activation
    • Amcheslavsky, A., O. Safrina, and M. D. Cahalan. 2014. State-dependent block of Orai3 TM1 and TM3 cysteine mutants: insights into 2-APB activation. J. Gen. Physiol. 143:621-631.
    • (2014) J. Gen. Physiol. , vol.143 , pp. 621-631
    • Amcheslavsky, A.1    Safrina, O.2    Cahalan, M.D.3
  • 61
    • 84895524321 scopus 로고    scopus 로고
    • Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria?
    • Lawlor, K. E., and J. E. Vince. 2014. Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria? Biochim. Biophys. Acta 1840:1433-1440.
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 1433-1440
    • Lawlor, K.E.1    Vince, J.E.2
  • 62
    • 84906852294 scopus 로고    scopus 로고
    • Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
    • Allam, R., K. E. Lawlor, E. C. Yu, A. L. Mildenhall, D. M. Moujalled, R. S. Lewis, F. Ke, K. D. Mason, M. J. White, K. J. Stacey, et al. 2014. Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming. EMBO Rep. 15:982-990.
    • (2014) EMBO Rep. , vol.15 , pp. 982-990
    • Allam, R.1    Lawlor, K.E.2    Yu, E.C.3    Mildenhall, A.L.4    Moujalled, D.M.5    Lewis, R.S.6    Ke, F.7    Mason, K.D.8    White, M.J.9    Stacey, K.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.