NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

Nature

Volumn 488, Issue 7411, 2012, Pages 389-393

  Anand, Paras K ^a   Subbarao Malireddi, R K ^a   Lukens, John R ^a   Vogel, Peter ^a   Bertin, John ^b   Lamkanfi, Mohamed ^c,d   Kanneganti, Thirumala Devi ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b GLAXOSMITHKLINE   (United States)

^c GHENT UNIVERSITY   (Belgium)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CHEMOKINE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR P6; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

BACTERIUM; BIOCHEMISTRY; DISEASE RESISTANCE; HOST-PATHOGEN INTERACTION; IMMUNITY; MOLECULAR ANALYSIS; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BACTERIAL INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; ENZYME ACTIVATION; ESCHERICHIA COLI; FEMALE; HEMATOPOIETIC CELL; HOST RESISTANCE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; IN VITRO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; INNATE IMMUNITY; LEUKOCYTE COUNT; LISTERIA MONOCYTOGENES; MONOCYTE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; REVIEW; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION;

ANIMALS; DISEASE SUSCEPTIBILITY; ESCHERICHIA COLI; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; IMMUNITY, INNATE; LISTERIA MONOCYTOGENES; MAP KINASE SIGNALING SYSTEM; MICE; MONOCYTES; NEUTROPHILS; NF-KAPPA B; RECEPTORS, CELL SURFACE; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LISTERIA MONOCYTOGENES; MUS; POSIBACTERIA; SALMONELLA TYPHIMURIUM;

EID: 84865130689     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11250     Document Type: Review

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