NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells

Immunity

Volumn 37, Issue 6, 2012, Pages 1009-1023

  Masters, Seth L ^a,b   Gerlic, Motti ^a,b   Metcalf, Donald ^a,b   Preston, Simon ^a,b   Pellegrini, Marc ^a,b   O'Donnell, Joanne A ^a,b   McArthur, Kate ^a,b   Baldwin, Tracey M ^a   Chevrier, Stephane ^a   Nowell, Cameron J ^c   Cengia, Louise H ^a   Henley, Katya J ^a   Collinge, Janelle E ^a   Kastner, Daniel L ^d   Feigenbaum, Lionel ^e   Hilton, Douglas J ^a,b   Alexander, Warren S ^a,b   Kile, Benjamin T ^a,b   Croker, Ben A ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c OLIVIA NEWTON JOHN CANCER RESEARCH INSTITUTE   (Australia)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^e SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NLRP1A PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW HYPOPLASIA; CELL DEATH; CONTROLLED STUDY; CYTOPENIA; HEMATOPOIETIC STEM CELL; IMMUNE DEFICIENCY; LEUKOPENIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PYROPTOSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; DERMATITIS; FLUOROURACIL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; INFLAMMASOMES; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; MUTATION; PANCYTOPENIA; T-LYMPHOCYTES;

EID: 84870950668     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.08.027     Document Type: Article

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