Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1β posttranslational processing

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 16567-16578

  Laliberte, Ronald E ^b   Perregaux, David G ^b   Hoth, Lise R ^b   Rosner, Philip J ^b   Jordan, Crystal K ^b   Peese, Kevin M ^b   Eggler, James F ^b   Dombroski, Mark A ^b   Geoghegan, Kieran F ^b   Gabel, Christopher A ^a  

^a PFIZER INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; BIOCHEMICAL ENGINEERING; CELL IMMOBILIZATION; CHEMICAL ACTIVATION; DRUG INTERACTIONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENESIS;

TRANSLATIONAL PROCESSINGS;

ANIMAL CELL CULTURE;

1 (1,2,3,5,6,7 HEXAHYDRO S INDACEN 4 YL) 3 [2 FLUORO 5 [2 AMINO 4 [1 (CARBOXYMETHYLCARBAMOYL) 2 (2 HYDROXYETHYLSULFANYL)ETHYLCARBAMOYL]BUTYRIC ACID]BENZENESULFONYL]UREA; 1 (1,2,3,5,6,7 HEXAHYDRO S INDACEN 4 YL) 3 [2 FLUORO 5 OXIRANYLBENZENESULFONYL]UREA; 1 (4 CHLORO 2,6 DIISOPROPYLPHENYL) 3 [2 FLUORO 5 OXIRANYLBENZENESULFONYL]UREA; ADENOSINE TRIPHOSPHATE; CARBON 14; CP 452759; CP 456773; CP 470947; CYSTEINE; CYTOKINE; CYTOKINE RELEASE INHIBITORY DRUG; GLUTATHIONE S TRANSFERASE OMEGA 1 1; GLUTATHIONE TRANSFERASE; INTERLEUKIN 1BETA; POLYPEPTIDE; RECOMBINANT PROTEIN; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG; INTERLEUKIN 1;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ARTICLE; CELL DEATH; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOTOPE LABELING; MASS SPECTROMETRY; MONOCYTE; PRIORITY JOURNAL; PROTEIN PROCESSING; BINDING SITE; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CELLS, CULTURED; CYSTEINE; GLUTATHIONE TRANSFERASE; HUMANS; INTERLEUKIN-1; MOLECULAR SEQUENCE DATA; MONOCYTES; MUTAGENESIS, SITE-DIRECTED; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

EID: 0037930829     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211596200     Document Type: Article

References (90)

1. Dinarello, C. A. (1998) Int. Rev. Immunol. 16, 457-499
2. Hogquist, K. A., Unanue, E. R., and Chaplin, D. D. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8485-8489
3. Perregaux, D., Barberia, J., Lanzetti, A. J., Geoghegan, K. F., Carty, T. J., and Gabel, C. A. (1992) J. Immunol. 149, 1294-1303
4. Rubartelli, A., Cozzolino, F., Talio, M., and Sitia, R. (1990) EMBO J. 9, 1503-1510
5. March, C. J., Mosley, B., Larsen, A., Cerretti, D. P., Braedt, G., Price, V., Gillis, S., Henney, C. S., Kronheim, S. R., Grabstein, K., Conlon, P. J., Hopp, T. P., and Cosman, D. (1985) Nature 315, 641-647
6. Auron, P. E., Webb, A. C., Rosenwasser, L. J., Mucci, S. F., Rich, A., Wolff, S. M., and Dinarello, C. A. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 7907-7911
7. Walter, P., and Johnson, A. E. (1994) Annu. Rev. Cell Biol. 10, 87-119
8. Traub, L. M., and Kornfeld, S. (1997) Curr. Opin. Cell Biol. 9, 527-533
9. Singer, I. I., Scott, S., Hall, G. L., Limjuco, G., Chin, J., and Schmidt, J. A. (1988) J. Exp. Med. 167, 389-407
10. Stevenson, F. T., Torrano, F., Locksley, R. M., and Lovett, D. H. (1992) J. Cell. Physiol. 152, 223-231
11. Mosley, B., Urdal, D. L., Prickett, K. S., Larsen, A., Cosman, D., Conlon, P. J., Gillis, S., and Dower, S. K. (1987) J. Biol. Chem. 262, 2941-2944
12. Cerretti, D. P., Kozlosky, D. J., Mosley, B., Nelson, N., Van Ness, K., Greenstreet, T. A., March, C. J., Kronheim, S. R., Druck, T., Cannizzaro, L. A., Huebner, K., and Black, R. A. (1992) Science 256, 97-100
13. Thornberry, N. A., Bull, H. C., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J., Elliston, K. O., Ayala, J. M., Casano, F. J., Chin, J., Ding, G. J.-F., Egger, L. A., Gaffney, E. P., Limjuco, G., Palyha, O. C., Raju, S. M., Rolando, A. M., Mumford, R. A., Schmidt, J. A., and Toeci, M. J. (1992) Nature 356, 768-774
14. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 312-316
15. Perregaux, D., and Gabel, C. A. (1994) J. Biol. Chem. 269, 15195-15203
16. Ferrari, D., Chiozzi, P., Falzoni, S., Dal Susino, M., Melchiorri, L., Baricordi, O. R., and Di Virgilio, F. (1997) J. Immunol. 159, 1451-1458
17. Cheneval, D., Ramage, P., Kastelic, T., Szelestenyi, T., Niggli, H., Hemmig, R., Bachmann, M., and MacKenzie, A. (1998) J. Biol. Chem. 273, 17846-17851
18. Bhakdi, S., Muhly, M., Korom, S., and Schmidt, G. (1990) J. Clin. Invest. 85, 7988-7992
19. Perregaux, D. G., Svensson, L., and Gabel, C. A. (1996) J. Immunol. 157, 57-64
20. Perregaux, D. G., Bhavsar, K, Contillo, L., Shi, J., and Gabel, C. A. (2002) J. Immunol. 168, 6436-6445
21. Walev, I., Reske, K., Palmer, M., Valeva, A., and Bhakdi, S. (1995) EMBO J. 14, 2821-2828
22. Hughes, F. M., Bortner, C. D., Purdy, G. D., and Cidlowski, J. A. (1997) J. Biol. Chem. 272, 30567-30576
23. Maeno, E., Ishizaki, Y., Kanaseki, T., Hazama, A., and Okada, Y. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 9487-9492
24. Thompson, G. J., Langlais, C., Cain, K., Conley, E. C., and Cohen, G. M. (2001) Biochem. J. 357, 137-145
25. Surprenant, A., Rassendren, F., Kawashima, E., North, R. A., and Buell, G. (1996) Science 272, 735-738
26. Rassendren, F., Buell, G. N., Virginio, C., Collo, G., North, R. A., and Surprenant, A. (1997) J. Biol. Chem. 272, 5482-5486
27. Michel, A. D., Chessell, I. P., Hibell, A. D., Simon, J., and Humphrey, P. P. A. (1998) Br. J. Pharmacol. 125, 1194-1201
28. Steinberg, T. H., Newman, A. S., Swanson, J. A., and Silverstein, S. C. (1987) J. Biol. Chem. 262, 8884-8888
29. Virginio, C., Mackenzie, A., North, R. A., and Surprenant, A. (1999) J. Physiol. 519, 335-346
30. Schilling, W. P., Wasylyna, T., Dubyak, G. R., Humphreys, B. D., and Sinkins, W. C. (1999) Am. J. Physiol. 277, C766-C776
31. Kim, M., Jiang, L.-H., Wilson, H. L., North, R. A., and Surprenant, A. (2001) EMBO J. 20, 6347-6358
32. Humphreys, B. D., Rice, J., Kertesy, S. B., and Dubyak, G. R. (2000) J. Biol. Chem. 275, 26792-26798
33. Hide, I., Tanaka, M., Inoue, A., Nakajima, K., Kohsaka, S., Inoue, K., and Nakata, Y. (2000) J. Neurochem. 75, 965-972
34. Ferrari, D., Wesselborg, S., Bauer, M. K. A., and Schulze-Osthoff, K. (1997) J. Cell Biol. 139, 1635-1643
35. El-Moatassim, C., and Dubyak, G. R. (1992) J. Biol. Chem. 267, 23664-23673
36. Alzola, E., Perez-Etxebarria, A., Kabre, E., Fogarty, D. J., Metioui, M., Chaib, N., Macarulla, J. M., Matute, C., Dehaye, J.-P., and Marion, A. (1998) J. Biol. Chem. 273, 30208-30217
37. Buisman, H. P., Steinberg, T. H., Fischbarg, J., Silverstein, S. C., Vogelzang, S. A., Ince, C., Ypey, D. L., and Leijh, P. C. J (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 7988-7992
38. Laliberte, R. E., Eggler, J., and Gabel, C. A. (1999) J. Biol. Chem. 274, 36944-36951
39. Ferrari, D., Chiozzi, P., Falzoni, S., Dal Susion, M., Collo, G., Buell, G., and Di Virgilio, F. (1997) Neuropharmacology 36, 1295-1301
40. Bresnihan, B., Alvaro-Garcia, J. M., Cobby, M., Doherty, M., Domljan, Z., Emery, P., Nuki, G., Pavelka, K., Rau, R., Bozman, B., Watt, I., Williams, B., Aitchison, R., McCabe, D., and Musikic, P. (1998) Arthritis Rheum. 41, 2196-2204
41. Miller, B. E., Krasney, P. A., Gauvin, D. M., Holbrook, K. B., Koonz, D. J., Abruzzese, R. V. Miller, R. E., Pagani, K. A., Dolle, R. E., Ator, M. A., and Gilman, S. C. (1995) J. Immunol. 154, 1032-1042
42. Williams, R. O., Marinova-Mutachieva, L., Feldmann, M., and Maini, R. N. (2000) J. Immunol. 165, 7240-7245
43. Joosten, L. A. B., Helsen, M. M. A., Saxne, T., van de Loo, F. A. J., Heinegard, D., and van den Berg, W. B. (1999) J. Immunol. 163, 5049-5055
44. Perregaux, D. G., McNiff, P., Laliberte, R., Hawryluk, N., Peurano, H., Stam, E., Eggler, J., Griffiths, R., Dombroski, M. A., and Gabel, C. A. (2001) J. Pharmacol. Exp. Ther. 299, 187-197
45. Eggler, J. F., Gabel, C. A., Zandi, K., Weaver, J. D., McKechney, H., Dombroski, M., Peurano, H., and Hawryluk, N. (2002) J. Label. Compd. Radiopharm. 45, 785-794
46. Jasys, V. J., and Urban, F. J. (2003) Syn. Comm. 33, in press
47. Vejdelek, Z. J., Bartosova, M., and Protiva, M. (1977) Collection Czechoslovak Chem. Commun. 42, 1992-2000
48. Ridderstrom, M., Cameron, A. D., Jones, T. A., and Mannervik, B. (1997) Biochem. J. 328, 231-235
49. Stone, K. L., and Williams, K. R. (1993) in A Practical Guide to Protein and Peptide Purification for Microsequencing (Matsudaira, P., ed) pp. 43-69, Academic Press, San Diego
50. Jonscher, K. R., and Yates, J. R. (1997) Anal. Biochem. 244, 1-15
51. Eng, J. K., McCormack, A. L., and Yates, J. R., III (1994) J. Am. Soc. Mass Spectrom. 5, 976-989
52. Board, P. G., Coggan, M., Chelvanayagam, G., Easteal, S., Jermiin, L. S., Schulte, G. K., Danley, D. E., Hoth, L. R., Griffor, M. C., Kamath, A. V., Rosner, M. H., Chrunyk, B. A., Perregaux, D. G., Gabel, C. A., Geoghegan, K. F., and Pandit, J. (2000) J. Biol. Chem. 275, 24798-24806
53. Geoghegan, K. F. (1996) in Current Protocols in Protein Science (Coligan, J. E., Dunn, B. M., Ploegh, H. L., Speicher, D. W., and Wingfield, P. T., eds) pp. 15.2.1-15.2.18, John Wiley, New York
54. Kodym, R., Calkins, P., and Story, M. (1999) J. Biol. Chem. 274, 5131-5137
55. Valenzuela, S. M., Martin, D. K., Por, S. B., Robbins, J. M., Bootcov, M. R., Schofield, P. R., Campbell, T. J., and Breit, S. N. (1997) J. Biol. Chem. 272, 12575-12582
56. Tulk, B. M., and Edwards, J. C. (1998) Am. J. Physiol. 43, F1140-F1149
57. Dulhunty, A., Gage, P., Curtis, S., Chelvanayagam, G., and Board, P. (2001) J. Biol. Chem. 276, 3319-3323
58. Munger, J. S., Shi, G.-P., Mark, E. A., Chin, D. T., Gerard, C., and Chapman, H. A. (1991) J. Biol. Chem. 266, 18832-18838
59. Rouimi, P, Anglade, P., Benzekri, A., Costet, P., Debrauwer, L., Pineau, T., and Tulliez, J. (2001) Biochem. J. 358, 257-262
60. Dirr, H., Reinemer, P., and Huber, R. (1994) Eur. J. Biochem. 220, 645-661
61. Clelland, J. D., Allen, R. E., and Thornalley, P. J. (1992) Biochem. Pharmacol. 44, 1953-1959
62. Laliberte, R., Perregaux, D., Svensson, L., Pazoles, C. J., and Gabel, C. A. (1994) J. Immunol. 153, 2168-2179
63. Harrop, S. J., DeMaere, M. Z., Fairlie, W. D., Reztsova, T., Valenzuela, S. M., Mazzanti, M., Tonini, R., Qiu, M. R., Jankova, L., Warton, K., Bauskin, A. R., Wu, W. M., Pankhurst, S., Campbell, T. J., Breit, S. N., and Curmi, P. M. G. (2001) J. Biol. Chem. 276, 44993-45000
64. Hayes, J. D., and McLellan, L. I. (1999) Free Radic. Res. 31, 273-300
65. Ahokas, J. T., Nicholls, F. A., Ravenscroft, P. J., and Emmerson, B. T. (1985) Biochem. Pharm. 34, 2157-2161
66. Sinning, I., Kleywegt, G. J., Cowan, S. W., Reinemer, P., Dirr, H. W., Huber, R., Gilliland, G. L., Armstrong, R. N., Ji, X., Board, P. G., Olin, B., Mannervik, B., and Jones, T. A. (1993) J. Mol. Biol. 232, 192-212
67. Wang, R. W., Newton, D. J., Huskey, S.-E. W., McKeever, B. M., Pickett, C. B., and Lu, A. Y. H. (1992) J. Biol. Chem. 267, 19866-19871
68. Xia, B., Vlamis-Gardikas, A., Holmgren, A., Wright, P. E., and Dyson, H. J. (2001) J. Mol. Biol. 310, 907-918
69. Ishikawa, T., Casini, A. F., and Nishikimi, M. (1998) J. Biol. Chem. 273, 28708-28712
70. Marrs, K. (1996) Annu. Rev. Plant Physiol. 47, 127-158
71. Rossjohn, J., Board, P. G., Parker, M. W., and Wilce, M. C. J. (1996) Protein Eng. 9, 327-332
72. Liebau, E., Eschbach, M.-L., Tawe, W., Sommer, A., Fischer, P., Walter, R. D., and Henkel-Duhrsen, K. (2000) Mol. Biochem. Parasitol. 109, 101-110
73. Perregaux, D. G., and Gabel C. A. (1998) Am. J. Physiol. 275, C1538-C1547
74. Perregaux, D. G., Laliberte, R. E., and Gabel, C. A. (1996) J. Biol. Chem. 271, 29830-29838
75. Ness, L. S., and Booth, I. R. (1999) J. Biol. Chem. 274, 9524-9530
76. Meury, J., and Robin, A. (1990) Arch. Microbiol. 154, 475-482
77. Park, J. B., and Levine, M. (1996) Biochem. J. 315, 931-938
78. Wells, W. W., Xu, D. P., and Washburn, M. P. (1995) Methods Enzymol. 252, 30-39
79. Parvathenani, L. K., Tertyshnikova, S., Greco, C. R., Roberts, S. B., Robertson, B., and Posmantur, R. (2003) J. Biol. Chem. 278, 13309-13317
80. Jahngen-Hodge, J., Obin, M. S., Gong, X., Shang, F., Nowell, Jr., T. R., Gong, J., Abasi, M., Blumberg, J., and Taylor, A. (1997) J. Biol. Chem. 272, 28218-28226
81. Eaton, P., Fuller, W., and Shattock, M. J. (2002) J. Biol. Chem. 277, 21189-21196
82. Sullivan, D. M., Wehr, N. B., Fergusson, M. M., Levine, R. L., and Finkel, T. (2000) Biochemistry 39, 11121-11228
83. Fratelli, M., Demon. H., Puype, M., Casagrande, S., Eberini, I., Salmona, M., Bonetto, V., Mengozzi, M., Duffieux, F., Miclet, E., Bachi, A., Vandekerckhove, J., Gianazza, E., and Ghezzi, P. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 3505-3510
84. Seres, T., Ravichandran, V., Moriguchi, T., Rokutan, K., Thomas, J. A., and Johnston, Jr., R. B. (1996) J. Immunol. 156, 1973-1980
85. Borges, C. R., Geddes, T., Watson, J. T., and Kuhn, D. M. (2002) J. Biol. Chem. 277, 48295-48302
86. Shenton, D., Perrone, G., Quinn, K. A., Dawes, I. W., and Grant, C. M. (2002) J. Biol. Chem. 277, 16853-16859
87. Nobel, C. S., Kimland, M., Nicholson, D. W., Orrenius, S., and Slater, A. F. G. (1997) Chem. Res. Toxicol. 10, 1319-1324
88. Hentze, H., Schmitz, I., Latta, M., Krueger, A., Krammer, P. H., and Wendel, A. (2002) J. Biol. Chem. 277, 5588-5595
89. Martinon, F, Burns, K, and Tschopp, J. (2002) Mol. Cell 10, 417-426
90. Dixon, D. P., Davis, B. G., and Edwards, R. (2002) J. Biol. Chem. 277, 30859-30869