Brief report: Connecting two pathways through Ca2+ signaling: NLRP3 inflammasome activation induced by a hypermorphic PLCG2 mutation

Arthritis and Rheumatology

Volumn 67, Issue 2, 2015, Pages 563-567

  Chae, Jae Jin ^a   Park, Yong Hwan ^a   Park, Chung ^b   Hwang, Il Young ^b   Hoffmann, Patrycja ^a   Kehrl, John H ^b   Aksentijevich, Ivona ^a   Kastner, Daniel L ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 6 (3 DIMETHYLAMINOPROPIONYL)FORSKOLIN; ADENYLATE CYCLASE; CALCIUM; CRYOPYRIN; CYCLIC AMP; INFLAMMASOME; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PHOSPHOLIPASE C GAMMA2; CALCIUM CHANNEL BLOCKING AGENT; CARRIER PROTEIN; NLRP3 PROTEIN, HUMAN; PHOSPHOLIPASE C GAMMA;

ANIMAL CELL; ARTICLE; AUTOINFLAMMATION PHOSPHOLIPASE C GAMMA2 ASSOCIATED ANTIBODY DEFICIENCY AND IMMUNE DYSREGULATION; AUTOINFLAMMATORY DISEASE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL STIMULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; HUMORAL IMMUNE DEFICIENCY; IMMUNE DYSREGULATION; LEUKOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; CASE CONTROL STUDY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENETICS; IMMUNE DEFICIENCY; IMMUNOPATHOLOGY; METABOLISM; MONONUCLEAR CELL; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CARRIER PROTEINS; CASE-CONTROL STUDIES; ENDOPLASMIC RETICULUM; HUMANS; IMMUNE SYSTEM DISEASES; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFLAMMASOMES; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MUTATION; PHOSPHOLIPASE C GAMMA; SIGNAL TRANSDUCTION;

EID: 84922762977     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38961     Document Type: Article

References (12)

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