-
1
-
-
0346186100
-
A key role for TRPM7 channels in anoxic neuronal death
-
Aarts, M., Iihara, K., Wei, W.L., Xiong, Z.G., Arundine, M., Cerwinski, W., MacDonald, J.F., and Tymianski, M. 2003. A key role for TRPM7 channels in anoxic neuronal death. Cell 115: 863-877.
-
(2003)
Cell
, vol.115
, pp. 863-877
-
-
Aarts, M.1
Iihara, K.2
Wei, W.L.3
Xiong, Z.G.4
Arundine, M.5
Cerwinski, W.6
MacDonald, J.F.7
Tymianski, M.8
-
2
-
-
4644258415
-
Regulatory pathways in photodynamic therapy induced apoptosis
-
Agostinis, P., Buytaert, E., Breyssens, H., and Hendrickx, N. 2004. Regulatory pathways in photodynamic therapy induced apoptosis. Photochem. Photobiol. Sci. 3: 721-729.
-
(2004)
Photochem. Photobiol. Sci.
, vol.3
, pp. 721-729
-
-
Agostinis, P.1
Buytaert, E.2
Breyssens, H.3
Hendrickx, N.4
-
3
-
-
4444265338
-
Intracellular signaling mechanisms in photodynamic therapy
-
Almeida, R.D., Manadas, B.J., Carvalho, A.P., and Duarte, C.B. 2004. Intracellular signaling mechanisms in photodynamic therapy. Biochim. Biophys. Acta 1704: 59-86.
-
(2004)
Biochim. Biophys. Acta
, vol.1704
, pp. 59-86
-
-
Almeida, R.D.1
Manadas, B.J.2
Carvalho, A.P.3
Duarte, C.B.4
-
4
-
-
25444469412
-
Mitochondrial metabolism of reactive oxygen species
-
Andreyev, A.Y., Kushnareva, Y.E., and Starkov, A.A. 2005. Mitochondrial metabolism of reactive oxygen species. Biochemistry 70: 200-214.
-
(2005)
Biochemistry
, vol.70
, pp. 200-214
-
-
Andreyev, A.Y.1
Kushnareva, Y.E.2
Starkov, A.A.3
-
5
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona, M., Dypbukt, J.M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S.A., and Nicotera, P. 1995. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15: 961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
6
-
-
0026619273
-
Deviant energetic metabolism of glycolytic cancer cells
-
Baggetto, L.G. 1992. Deviant energetic metabolism of glycolytic cancer cells. Biochimie 74: 959-974.
-
(1992)
Biochimie
, vol.74
, pp. 959-974
-
-
Baggetto, L.G.1
-
7
-
-
0041816087
-
Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo
-
Bai, X., Cerimele, F., Ushio-Fukai, M., Waqas, M., Campbell, P.M., Govindarajan, B., Der, C.J., Battle, T., Frank, D.A., Ye, K., et al. 2003. Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo. J. Biol. Chem. 278: 35501-35507.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35501-35507
-
-
Bai, X.1
Cerimele, F.2
Ushio-Fukai, M.3
Waqas, M.4
Campbell, P.M.5
Govindarajan, B.6
Der, C.J.7
Battle, T.8
Frank, D.A.9
Ye, K.10
-
8
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines, C.P., Kaiser, R.A., Purcell, N.H., Blair, N.S., Osinska, H., Hambleton, M.A., Brunskill, E.W., Sayen, M.R., Gottlieb, R.A., Dorn, G.W., et al. 2005. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434: 658-662.
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
-
9
-
-
12944297732
-
2+ exchanger in excitotoxicity
-
2+ exchanger in excitotoxicity. Cell 120: 275-285.
-
(2005)
Cell
, vol.120
, pp. 275-285
-
-
Bano, D.1
Young, K.W.2
Guerin, C.J.3
Lefeuvre, R.4
Rothwell, N.J.5
Naldini, L.6
Rizzuto, R.7
Carafoli, E.8
Nicotera, P.9
-
10
-
-
21244446551
-
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D
-
Basso, E., Fante, L., Fowlkes, J., Petronilli, V., Forte, M.A., and Bernardi. P. 2005. Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. J. Biol. Chem. 280: 18558-18561.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18558-18561
-
-
Basso, E.1
Fante, L.2
Fowlkes, J.3
Petronilli, V.4
Forte, M.A.5
Bernardi, P.6
-
11
-
-
6344227760
-
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand
-
Bauer, D.E., Harris, M.H., Plas, D.R., Lum, J.J., Hammerman, P.S., Rathmell, J.C., Riley, J.L., and Thompson, C.B. 2004. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J. 18: 1303-1305.
-
(2004)
FASEB J.
, vol.18
, pp. 1303-1305
-
-
Bauer, D.E.1
Harris, M.H.2
Plas, D.R.3
Lum, J.J.4
Hammerman, P.S.5
Rathmell, J.C.6
Riley, J.L.7
Thompson, C.B.8
-
12
-
-
0035866407
-
Apoptosis induction by the photosensitizer verteporfin: Identification of mitochondrial adenine nucleotide translocator as a critical target
-
Belzacq, A.S., Jacotot, E., Vieira, H.L., Mistro, D., Granville, D.J., Xie, Z., Reed, J.C., Kroemer, G., and Brenner, C. 2001. Apoptosis induction by the photosensitizer verteporfin: Identification of mitochondrial adenine nucleotide translocator as a critical target. Cancer Res. 61: 1260-1264.
-
(2001)
Cancer Res.
, vol.61
, pp. 1260-1264
-
-
Belzacq, A.S.1
Jacotot, E.2
Vieira, H.L.3
Mistro, D.4
Granville, D.J.5
Xie, Z.6
Reed, J.C.7
Kroemer, G.8
Brenner, C.9
-
13
-
-
0036852215
-
To kill or be killed: Viral evasion of apoptosis
-
Benedict, C.A., Norris, P.S., and Ware, C.F. 2002. To kill or be killed: Viral evasion of apoptosis. Nat. Immunol. 3: 1013-1018.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1013-1018
-
-
Benedict, C.A.1
Norris, P.S.2
Ware, C.F.3
-
14
-
-
0020980976
-
Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: Studies in normal and DNA-repair defective cells
-
Berger, N.A., Sims, J.L., Catino, D.M., and Berger, S.J. 1983. Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: Studies in normal and DNA-repair defective cells. Princess Takamatsu Symp. 13: 219-226.
-
(1983)
Princess Takamatsu Symp.
, vol.13
, pp. 219-226
-
-
Berger, N.A.1
Sims, J.L.2
Catino, D.M.3
Berger, S.J.4
-
15
-
-
0032521673
-
G αs-induced neurodegeneration in Caenorhabditis elegans
-
Berger, A.J., Hart, A.C., and Kaplan, J.M. 1998. G αs-induced neurodegeneration in Caenorhabditis elegans. J. Neurosci. 18: 2871-2880.
-
(1998)
J. Neurosci.
, vol.18
, pp. 2871-2880
-
-
Berger, A.J.1
Hart, A.C.2
Kaplan, J.M.3
-
16
-
-
0028826727
-
Capacitative calcium entry
-
Berridge, M.J. 1995. Capacitative calcium entry. Biochem. J. 312: 1-11.
-
(1995)
Biochem. J.
, vol.312
, pp. 1-11
-
-
Berridge, M.J.1
-
17
-
-
0035877850
-
Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96
-
Berwin, B., Reed, R.C., and Nicchitta, C.V. 2001. Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96. J. Biol. Chem. 276: 21083-21088.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21083-21088
-
-
Berwin, B.1
Reed, R.C.2
Nicchitta, C.V.3
-
18
-
-
13744255990
-
The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: Implications for necrosis initiation
-
Bianchi, L., Gerstbrein, B., Frokjaer-Jensen, C., Royal, D.C., Mukherjee, G., Royal, M.A., Xue, J., Schafer, W.R., and Driscoll, M. 2004. The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: Implications for necrosis initiation. Nat. Neurosci. 7: 1337-1344.
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 1337-1344
-
-
Bianchi, L.1
Gerstbrein, B.2
Frokjaer-Jensen, C.3
Royal, D.C.4
Mukherjee, G.5
Royal, M.A.6
Xue, J.7
Schafer, W.R.8
Driscoll, M.9
-
19
-
-
0035252660
-
Salmonella-induced cell death: Apoptosis, necrosis or programmed cell death?
-
Boise, L.H. and Collins, C.M. 2001. Salmonella-induced cell death: Apoptosis, necrosis or programmed cell death? Trends Microbiol. 9: 64-67.
-
(2001)
Trends Microbiol.
, vol.9
, pp. 64-67
-
-
Boise, L.H.1
Collins, C.M.2
-
20
-
-
0036239252
-
Death of CD4(+) T-cell lines caused by human immunodeficiency virus type 1 does not depend on caspases or apoptosis
-
Bolton, D.L., Hahn, B.I., Park, E.A., Lehnhoff, L.L., Hornung, F., and Lenardo, M.J. 2002. Death of CD4(+) T-cell lines caused by human immunodeficiency virus type 1 does not depend on caspases or apoptosis. J. Virol. 76: 5094-5107.
-
(2002)
J. Virol.
, vol.76
, pp. 5094-5107
-
-
Bolton, D.L.1
Hahn, B.I.2
Park, E.A.3
Lehnhoff, L.L.4
Hornung, F.5
Lenardo, M.J.6
-
21
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant, H.E., Schultz, N., Thomas, H.D., Parker, K.M., Flower, D., Lopez, E., Kyle, S., Meuth, M., Curtin, N.J., and Helleday, T. 2005. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434: 913-917.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
22
-
-
0032544449
-
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi, F., Alvarez-Bolado, G., Meyer, B.I., Roth, K.A., and Gruss, P. 1998. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94: 727-737.
-
(1998)
Cell
, vol.94
, pp. 727-737
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
24
-
-
0033539141
-
Interdigital cell death can occur through a necrotic and caspase-independent pathway
-
Chautan, M., Chazal, G., Cecconi, F., Gruss, P., and Golstein, P. 1999. Interdigital cell death can occur through a necrotic and caspase-independent pathway. Curr. Biol. 9: 967-970.
-
(1999)
Curr. Biol.
, vol.9
, pp. 967-970
-
-
Chautan, M.1
Chazal, G.2
Cecconi, F.3
Gruss, P.4
Golstein, P.5
-
25
-
-
0035917568
-
Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy
-
Chiu, S.M. and Oleinick, N.L. 2001. Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy. Br. J. Cancer 84: 1099-1106.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1099-1106
-
-
Chiu, S.M.1
Oleinick, N.L.2
-
26
-
-
0033671313
-
A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans
-
Chung, S., Gumienny, T.L., Hengartner, M.O., and Driscoll, M. 2000. A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans. Nat. Cell. Biol. 2: 931-937.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 931-937
-
-
Chung, S.1
Gumienny, T.L.2
Hengartner, M.O.3
Driscoll, M.4
-
27
-
-
20444454999
-
Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction
-
Cipriani, G., Rapizzi, E., Vannacci, A., Rizzuto, R., Moroni, F., and Chiarugi, A. 2005. Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction. J. Biol. Chem. 280: 17227-17234.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17227-17234
-
-
Cipriani, G.1
Rapizzi, E.2
Vannacci, A.3
Rizzuto, R.4
Moroni, F.5
Chiarugi, A.6
-
28
-
-
0037144409
-
Sanglifehrin a acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A
-
Clarke, S.J., McStay, G.P., and Halestrap, A.P. 2002. Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A. J. Biol. Chem. 277: 34793-34799.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34793-34799
-
-
Clarke, S.J.1
McStay, G.P.2
Halestrap, A.P.3
-
29
-
-
9644277091
-
Sphingolipid metabolites in neural signalling and function
-
Colombaioni, L. and Garcia-Gil, M. 2004. Sphingolipid metabolites in neural signalling and function. Brain Res. Brain Res. Rev. 46: 328-355.
-
(2004)
Brain Res. Brain Res. Rev.
, vol.46
, pp. 328-355
-
-
Colombaioni, L.1
Garcia-Gil, M.2
-
30
-
-
0035283318
-
Pro-inflammatory programmed cell death
-
Cookson, B.T. and Brennan, M.A. 2001. Pro-inflammatory programmed cell death. Trends Microbiol. 9: 113-114.
-
(2001)
Trends Microbiol.
, vol.9
, pp. 113-114
-
-
Cookson, B.T.1
Brennan, M.A.2
-
31
-
-
0023391047
-
2+-dependent pore activated by oxidative stress in heart mitochondria
-
2+-dependent pore activated by oxidative stress in heart mitochondria. Biochem. J. 245: 915-918.
-
(1987)
Biochem. J.
, vol.245
, pp. 915-918
-
-
Crompton, M.1
Costi, A.2
Hayat, L.3
-
32
-
-
0036791781
-
Viral homologs of BCL-2: Role of apoptosis in the regulation of virus infection
-
Cuconati, A. and White, E. 2002. Viral homologs of BCL-2: Role of apoptosis in the regulation of virus infection. Genes & Dev. 16: 2465-2478.
-
(2002)
Genes & Dev.
, vol.16
, pp. 2465-2478
-
-
Cuconati, A.1
White, E.2
-
33
-
-
0037203316
-
Sphingosine in apoptosis signaling
-
Cuvillier, O. 2002. Sphingosine in apoptosis signaling. Biochim. Biophys. Acta 1585: 153-162.
-
(2002)
Biochim. Biophys. Acta
, vol.1585
, pp. 153-162
-
-
Cuvillier, O.1
-
34
-
-
0033198919
-
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours, D., Desnoyers, S., D'Silva, I., and Poirier, G.G. 1999. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342: 249-268.
-
(1999)
Biochem. J.
, vol.342
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
Poirier, G.G.4
-
35
-
-
0021040946
-
Lysosomes revisited
-
de Duve, C. 1983. Lysosomes revisited. Eur. J. Biochem. 137: 391-397.
-
(1983)
Eur. J. Biochem.
, vol.137
, pp. 391-397
-
-
De Duve, C.1
-
36
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., Cuny, G.D., Mitchison, T.J., Moskowitz, M.A., and Yuan, J. 2005. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat. Chem. Biol. 1: 112-119.
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
37
-
-
0000102949
-
Poly(ADP-ribose) polymerase: A molecular nick-sensor
-
de Murcia, G. and Menissier de Murcia, J. 1994. Poly(ADP-ribose) polymerase: A molecular nick-sensor. Trends Biochem Sci. 19: 172-176.
-
(1994)
Trends Biochem Sci.
, vol.19
, pp. 172-176
-
-
De Murcia, G.1
Menissier De Murcia, J.2
-
38
-
-
0040984333
-
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
-
de Murcia, J.M., Niedergang, C., Trucco, C., Ricoul, M., Dutrillaux, B., Mark, M., Oliver, F.J., Masson, M., Dierich, A., LeMeur, M., et al. 1997. Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc. Natl. Acad. Sci. 94: 7303-7307.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 7303-7307
-
-
De Murcia, J.M.1
Niedergang, C.2
Trucco, C.3
Ricoul, M.4
Dutrillaux, B.5
Mark, M.6
Oliver, F.J.7
Masson, M.8
Dierich, A.9
LeMeur, M.10
-
39
-
-
0025994345
-
Protons in ischemia: Where do they come from; where do they go to?
-
Dennis, S.C., Gevers, W., and Opie, L.H. 1991. Protons in ischemia: Where do they come from; where do they go to? J. Mol. Cell. Cardiol. 23: 1077-1086.
-
(1991)
J. Mol. Cell Cardiol.
, vol.23
, pp. 1077-1086
-
-
Dennis, S.C.1
Gevers, W.2
Opie, L.H.3
-
40
-
-
0026089774
-
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration
-
Driscoll, M. and Chalfie, M. 1991. The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration. Nature 349: 588-593.
-
(1991)
Nature
, vol.349
, pp. 588-593
-
-
Driscoll, M.1
Chalfie, M.2
-
41
-
-
0038043242
-
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress
-
Du, L., Zhang, X., Han, Y.Y., Burke, N.A., Kochanek, P.M., Watkins, S.C., Graham, S.H., Carcillo, J.A., Szabo, C., and Clark, R.S. 2003. Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress. J. Biol. Chem. 278: 18426-18433.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18426-18433
-
-
Du, L.1
Zhang, X.2
Han, Y.Y.3
Burke, N.A.4
Kochanek, P.M.5
Watkins, S.C.6
Graham, S.H.7
Carcillo, J.A.8
Szabo, C.9
Clark, R.S.10
-
42
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase
-
Endres, M., Wang, Z.Q., Namura, S., Waeber, C., and Moskowitz, M.A. 1997. Ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase. J. Cereb. Blood Flow Metab. 17: 1143-1151.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
43
-
-
0035887462
-
Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis
-
Fabris, C., Valduga, G., Miotto, G., Borsetto, L., Jori, G., Garbisa, S., and Reddi, E. 2001. Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis. Cancer Res. 61: 7495-7500.
-
(2001)
Cancer Res.
, vol.61
, pp. 7495-7500
-
-
Fabris, C.1
Valduga, G.2
Miotto, G.3
Borsetto, L.4
Jori, G.5
Garbisa, S.6
Reddi, E.7
-
44
-
-
0026508561
-
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
-
Fadok, V.A., Voelker, D.R., Campbell, P.A., Cohen, J.J., Bratton, D.L., and Henson, P.M. 1992. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148: 2207-2216.
-
(1992)
J. Immunol.
, vol.148
, pp. 2207-2216
-
-
Fadok, V.A.1
Voelker, D.R.2
Campbell, P.A.3
Cohen, J.J.4
Bratton, D.L.5
Henson, P.M.6
-
45
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer, H., McCabe, N., Lord, C.J., Tutt, A.N., Johnson, D.A., Richardson, T.B., Santarosa, M., Dillon, K.J., Hickson, I., Knights, C., et al. 2005. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434: 917-921.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
-
46
-
-
34848923447
-
The ionic requirements for the production of action potentials in crustacean muscle fibres
-
Fatt, P. and Ginsborg, B.L. 1958. The ionic requirements for the production of action potentials in crustacean muscle fibres. J. Physiol. 142: 516-543.
-
(1958)
J. Physiol.
, vol.142
, pp. 516-543
-
-
Fatt, P.1
Ginsborg, B.L.2
-
47
-
-
14644413468
-
Death begets failure in the heart
-
Foo, R.S., Mani, K., and Kitsis, R.N. 2005. Death begets failure in the heart. J. Clin. Invest. 115: 565-571.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 565-571
-
-
Foo, R.S.1
Mani, K.2
Kitsis, R.N.3
-
48
-
-
0032924609
-
Excitotoxic death of a subset of embryonic rat motor neurons in vitro
-
Fryer, H.J., Knox, R.J., Strittmatter, S.M., and Kalb, R.G. 1999. Excitotoxic death of a subset of embryonic rat motor neurons in vitro. J. Neurochem. 72: 500-513.
-
(1999)
J. Neurochem.
, vol.72
, pp. 500-513
-
-
Fryer, H.J.1
Knox, R.J.2
Strittmatter, S.M.3
Kalb, R.G.4
-
49
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior, P. and Salvesen, G.S. 2004. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 384: 201-232.
-
(2004)
Biochem. J.
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
50
-
-
0345772125
-
Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor
-
Golab, J., Nowis, D., Skrzycki, M., Czeczot, H., Baranczyk-Kuzma, A., Wilczynski, G.M., Makowski, M., Mroz, P., Kozar, K., Kaminski, R., et al. 2003. Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor. J. Biol. Chem. 278: 407-414.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 407-414
-
-
Golab, J.1
Nowis, D.2
Skrzycki, M.3
Czeczot, H.4
Baranczyk-Kuzma, A.5
Wilczynski, G.M.6
Makowski, M.7
Mroz, P.8
Kozar, K.9
Kaminski, R.10
-
51
-
-
0038337815
-
The calpain system
-
Goll, D.E., Thompson, V.F., Li, H., Wei, W., and Cong, J. 2003. The calpain system. Physiol. Rev. 83: 731-801.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
52
-
-
0037086260
-
Generation of effective antitumor vaccines using photodynamic therapy
-
Gollnick, S.O., Vaughan, L., and Henderson, B.W. 2002. Generation of effective antitumor vaccines using photodynamic therapy. Cancer Res. 62: 1604-1608.
-
(2002)
Cancer Res.
, vol.62
, pp. 1604-1608
-
-
Gollnick, S.O.1
Vaughan, L.2
Henderson, B.W.3
-
53
-
-
0032717067
-
Redox regulation of TNF signaling
-
Goossens, V., De Vos, K., Vercammen, D., Steemans, M., Vancompernolle, K., Fiers, W., Vandenabeele, P., and Grooten, J. 1999. Redox regulation of TNF signaling. Biofactors 10: 145-156.
-
(1999)
Biofactors
, vol.10
, pp. 145-156
-
-
Goossens, V.1
De Vos, K.2
Vercammen, D.3
Steemans, M.4
Vancompernolle, K.5
Fiers, W.6
Vandenabeele, P.7
Grooten, J.8
-
54
-
-
0029885316
-
Preconditioning rabbit cardiomyocytes: Role of pH, vacuolar proton ATPase, and apoptosis
-
Gottlieb, R.A., Gruol, D.L., Zhu, J.Y., and Engler, R.L. 1996. Preconditioning rabbit cardiomyocytes: Role of pH, vacuolar proton ATPase, and apoptosis. J. Clin. Invest. 97: 2391-2398.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2391-2398
-
-
Gottlieb, R.A.1
Gruol, D.L.2
Zhu, J.Y.3
Engler, R.L.4
-
55
-
-
0038725688
-
Apoptosis as an HIV strategy to escape immune attack
-
Gougeon, M.L. 2003. Apoptosis as an HIV strategy to escape immune attack. Nat. Rev. Immunol. 3: 392-404.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 392-404
-
-
Gougeon, M.L.1
-
56
-
-
14144254640
-
Neuronal cell death in alphavirus encephalomyelitis
-
Griffin, D.E. 2005. Neuronal cell death in alphavirus encephalomyelitis. Curr. Top. Microbiol. Immunol. 289: 57-77.
-
(2005)
Curr. Top. Microbiol. Immunol.
, vol.289
, pp. 57-77
-
-
Griffin, D.E.1
-
57
-
-
0028968606
-
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion
-
Griffiths, E.J. and Halestrap, A.P. 1995. Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem. J. 307: 93-98.
-
(1995)
Biochem. J.
, vol.307
, pp. 93-98
-
-
Griffiths, E.J.1
Halestrap, A.P.2
-
58
-
-
14144255527
-
The role of host cell death in Salmonella infections
-
Guiney, D.G. 2005. The role of host cell death in Salmonella infections. Curr. Top. Microbiol. Immunol. 289: 131-150.
-
(2005)
Curr. Top. Microbiol. Immunol.
, vol.289
, pp. 131-150
-
-
Guiney, D.G.1
-
59
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha, H.C. and Snyder, S.H. 1999. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl. Acad. Sci. 96: 13978-13982.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
60
-
-
0030826778
-
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury
-
Halestrap, A.P., Connern, C.P., Griffiths, E.J., and Kerr, P.M. 1997. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol. Cell. Biochem. 174: 167-172.
-
(1997)
Mol. Cell Biochem.
, vol.174
, pp. 167-172
-
-
Halestrap, A.P.1
Connern, C.P.2
Griffiths, E.J.3
Kerr, P.M.4
-
61
-
-
84975751684
-
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
-
Hartley, A., Stone, J.M., Heron, C., Cooper, J.M., and Schapira, A.H. 1994. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease. J. Neurochem. 63: 1987-1990.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1987-1990
-
-
Hartley, A.1
Stone, J.M.2
Heron, C.3
Cooper, J.M.4
Schapira, A.H.5
-
63
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler, N., Zaru, R., Micheau, O., Thome, M., Attinger, A., Valitutti, S., Bodmer, J.L., Schneider, P., Seed, B., and Tschopp, J. 2000. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat. Immunol. 1: 489-495.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
64
-
-
0020533243
-
Cancer, a disease of defective glucose metabolism
-
Holt, J.A. 1983. Cancer, a disease of defective glucose metabolism. Med. Hypotheses 10: 133-150.
-
(1983)
Med. Hypotheses
, vol.10
, pp. 133-150
-
-
Holt, J.A.1
-
65
-
-
0037362431
-
Subcellular localization of Photofrin determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: When plasma membranes are the main targets
-
Hsieh, Y.J., Wu, C.C., Chang, C.J., and Yu, J.S. 2003. Subcellular localization of Photofrin determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: When plasma membranes are the main targets. J. Cell Physiol. 194: 363-375.
-
(2003)
J. Cell Physiol.
, vol.194
, pp. 363-375
-
-
Hsieh, Y.J.1
Wu, C.C.2
Chang, C.J.3
Yu, J.S.4
-
66
-
-
0028127759
-
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
-
Huang, M. and Chalfie, M. 1994. Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans. Nature 367: 467-470.
-
(1994)
Nature
, vol.367
, pp. 467-470
-
-
Huang, M.1
Chalfie, M.2
-
67
-
-
6344277362
-
Salmonella-induced macrophage death: Multiple mechanisms, different outcomes
-
Hueffer, K. and Galan, J.E. 2004. Salmonella-induced macrophage death: Multiple mechanisms, different outcomes. Cell Microbiol. 6: 1019-1025.
-
(2004)
Cell Microbiol.
, vol.6
, pp. 1019-1025
-
-
Hueffer, K.1
Galan, J.E.2
-
68
-
-
0018332596
-
2+-induced membrane transition in mitochondria. I. The protective mechanisms
-
2+-induced membrane transition in mitochondria. I. The protective mechanisms. Arch. Biochem. Biophys. 195: 453-459.
-
(1979)
Arch. Biochem. Biophys.
, vol.195
, pp. 453-459
-
-
Hunter, D.R.1
Haworth, R.A.2
-
69
-
-
0018332598
-
2+ release
-
2+ release. Arch. Biochem. Biophys. 195: 468-477.
-
(1979)
Arch. Biochem. Biophys.
, vol.195
, pp. 468-477
-
-
-
70
-
-
0033212190
-
Effects of BAPTA-AM and forskolin on apoptosis and cytochrome c release in photosensitized Chinese hamster V79 cells
-
Inanami, O., Yoshito, A., Takahashi, K., Hiraoka, W., and Kuwabara, M. 1999. Effects of BAPTA-AM and forskolin on apoptosis and cytochrome c release in photosensitized Chinese hamster V79 cells. Photochem. Photobiol. 70: 650-655.
-
(1999)
Photochem. Photobiol.
, vol.70
, pp. 650-655
-
-
Inanami, O.1
Yoshito, A.2
Takahashi, K.3
Hiraoka, W.4
Kuwabara, M.5
-
71
-
-
4344644507
-
Neuronal apoptosis pathways in Sindbis virus encephalitis
-
Irusta, P.M. and Hardwick, J.M. 2004. Neuronal apoptosis pathways in Sindbis virus encephalitis. Prog. Mol. Subcell. Biol. 36: 71-93.
-
(2004)
Prog. Mol. Subcell. Biol.
, vol.36
, pp. 71-93
-
-
Irusta, P.M.1
Hardwick, J.M.2
-
72
-
-
0037376729
-
Caspase-1 activation by Salmonella
-
Jarvelainen, H.A., Galmiche, A., and Zychlinsky, A. 2003. Caspase-1 activation by Salmonella. Trends Cell. Biol. 13: 204-209.
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 204-209
-
-
Jarvelainen, H.A.1
Galmiche, A.2
Zychlinsky, A.3
-
73
-
-
0035887215
-
Sphingosine-induced apoptosis is dependent on lysosomal proteases
-
Kagedal, K., Zhao, M., Svensson, I., and Brunk, U.T. 2001. Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem. J. 359: 335-343.
-
(2001)
Biochem. J.
, vol.359
, pp. 335-343
-
-
Kagedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
74
-
-
0032583164
-
Caspase-independent cell killing by Fas-associated protein with death domain
-
Kawahara, A., Ohsawa, Y., Matsumura, H., Uchiyama, Y., and Nagata, S. 1998. Caspase-independent cell killing by Fas-associated protein with death domain. J. Cell. Biol. 143: 1353-1360.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1353-1360
-
-
Kawahara, A.1
Ohsawa, Y.2
Matsumura, H.3
Uchiyama, Y.4
Nagata, S.5
-
75
-
-
0015117787
-
Shrinkage necrosis: A distinct mode of cellular death
-
Kerr, J.F. 1971. Shrinkage necrosis: A distinct mode of cellular death. J. Pathol. 105: 13-20.
-
(1971)
J. Pathol.
, vol.105
, pp. 13-20
-
-
Kerr, J.F.1
-
76
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr, J.F., Wyllie, A.H., and Currie, A.R. 1972. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26: 239-257.
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
77
-
-
24344454692
-
Poly(ADP-ribosyl) ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal
-
Kim, M.Y., Zhang, T., and Kraus, W.L. 2005. Poly(ADP-ribosyl) ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal. Genes & Dev. 19: 1951-1967.
-
(2005)
Genes & Dev.
, vol.19
, pp. 1951-1967
-
-
Kim, M.Y.1
Zhang, T.2
Kraus, W.L.3
-
78
-
-
0842307483
-
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
-
Kokoszka, J.E., Waymire, K.G., Levy, S.E., Sligh, J.E., Cai, J., Jones, D.P., MacGregor, G.R., and Wallace, D.C. 2004. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427: 461-465.
-
(2004)
Nature
, vol.427
, pp. 461-465
-
-
Kokoszka, J.E.1
Waymire, K.G.2
Levy, S.E.3
Sligh, J.E.4
Cai, J.5
Jones, D.P.6
MacGregor, G.R.7
Wallace, D.C.8
-
79
-
-
0030969879
-
An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration
-
Korswagen, H.C., Park, J.H., Ohshima, Y., and Plasterk, R.H. 1997. An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration. Genes & Dev. 11: 1493-1503.
-
(1997)
Genes & Dev.
, vol.11
, pp. 1493-1503
-
-
Korswagen, H.C.1
Park, J.H.2
Ohshima, Y.3
Plasterk, R.H.4
-
80
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 β converting enzyme
-
Kuida, K., Lippke, J.A., Ku, G., Harding, M.W., Livingston, D.J., Su, M.S., and Flavell, R.A. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 β converting enzyme. Science 267: 2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
81
-
-
0038820117
-
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal
-
Lauber, K., Bohn, E., Krober, S.M., Xiao, Y.J., Blumenthal, S.G., Lindemann, R.K., Marini, P., Wiedig, C., Zobywalski, A., Baksh, S., et al. 2003. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 113: 717-730.
-
(2003)
Cell
, vol.113
, pp. 717-730
-
-
Lauber, K.1
Bohn, E.2
Krober, S.M.3
Xiao, Y.J.4
Blumenthal, S.G.5
Lindemann, R.K.6
Marini, P.7
Wiedig, C.8
Zobywalski, A.9
Baksh, S.10
-
82
-
-
0032897568
-
V. Necrapoptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis
-
Lemasters, J.J. 1999. V. Necrapoptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis. Am. J. Physiol. 276: G1-G6.
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Lemasters, J.J.1
-
83
-
-
0036233343
-
Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env
-
Lenardo, M.J., Angleman, S.B., Bounkeua, V., Dimas, J., Duvall, M.G., Graubard, M.B., Hornung, F., Selkirk, M.C., Speirs, C.K., Trageser, C., et al. 2002. Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env. J. Virol. 76: 5082-5093.
-
(2002)
J. Virol.
, vol.76
, pp. 5082-5093
-
-
Lenardo, M.J.1
Angleman, S.B.2
Bounkeua, V.3
Dimas, J.4
Duvall, M.G.5
Graubard, M.B.6
Hornung, F.7
Selkirk, M.C.8
Speirs, C.K.9
Trageser, C.10
-
84
-
-
0028984948
-
Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock
-
Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J., et al. 1995. Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock. Cell 80: 401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
85
-
-
0033045065
-
Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by β-lapachone in human carcinoma cells
-
Li, Y.Z., Li, C.J., Pinto, A.V., and Pardee, A.B. 1999. Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by β-lapachone in human carcinoma cells. Mol. Med. 5: 232-239.
-
(1999)
Mol. Med.
, vol.5
, pp. 232-239
-
-
Li, Y.Z.1
Li, C.J.2
Pinto, A.V.3
Pardee, A.B.4
-
86
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
-
Lindsten, T., Ross, A.J., King, A., Zong, W.X., Rathmell, J.C., Shiels, H.A., Ulrich, E., Waymire, K.G., Mahar, P., Frauwirth, K., et al. 2000. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol. Cell 6: 1389-1399.
-
(2000)
Mol. Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.X.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
-
87
-
-
0348010297
-
The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool
-
Lindsten, T., Golden, J.A., Zong, W.X., Minarcik, J., Harris, M.H., and Thompson, C.B. 2003. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. J. Neurosci. 23: 11112-11119.
-
(2003)
J. Neurosci.
, vol.23
, pp. 11112-11119
-
-
Lindsten, T.1
Golden, J.A.2
Zong, W.X.3
Minarcik, J.4
Harris, M.H.5
Thompson, C.B.6
-
88
-
-
1342281236
-
The role of calpain in oncotic cell death
-
Liu, X., Van Vleet, T., and Schnellmann, R.G. 2004. The role of calpain in oncotic cell death. Annu. Rev. Pharmacol. Toxicol. 44: 349-370.
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 349-370
-
-
Liu, X.1
Van Vleet, T.2
Schnellmann, R.G.3
-
89
-
-
11044236031
-
Ischemia/reperfusion injury at the intersection with cell death
-
Logue, S.E., Gustafsson, A.B., Samali, A., and Gottlieb, R.A. 2005. Ischemia/reperfusion injury at the intersection with cell death. J. Mol. Cell. Cardiol. 38: 21-33.
-
(2005)
J. Mol. Cell Cardiol.
, vol.38
, pp. 21-33
-
-
Logue, S.E.1
Gustafsson, A.B.2
Samali, A.3
Gottlieb, R.A.4
-
90
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
Lotze, M.T. and Tracey, K.J. 2005. High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5: 331-342.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
91
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum, J.J., Bauer, D.E., Kong, M., Harris, M.H., Li, C., Lindsten, T., and Thompson, C.B. 2005. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120: 237-248.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
92
-
-
0028891783
-
Apoptosis, oncosis, and necrosis. An overview of cell death
-
Majno, G. and Joris, I. 1995. Apoptosis, oncosis, and necrosis. An overview of cell death. Am. J. Pathol. 146: 3-15.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 3-15
-
-
Majno, G.1
Joris, I.2
-
93
-
-
0034011261
-
Oxyradicals and DNA damage
-
Marnett, L.J. 2000. Oxyradicals and DNA damage. Carcinogenesis 21: 361-370.
-
(2000)
Carcinogenesis
, vol.21
, pp. 361-370
-
-
Marnett, L.J.1
-
94
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
Marzo, I., Brenner, C., Zamzami, N., Jurgensmeier, J.M., Susin, S.A., Vieira, H.L., Prevost, M.C., Xie, Z., Matsuyama, S., Reed, J.C., et al. 1998. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281: 2027-2031.
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Jurgensmeier, J.M.4
Susin, S.A.5
Vieira, H.L.6
Prevost, M.C.7
Xie, Z.8
Matsuyama, S.9
Reed, J.C.10
-
95
-
-
0029938521
-
The role of calcium in the regulation of apoptosis
-
McConkey, D.J. and Orrenius, S. 1996. The role of calcium in the regulation of apoptosis. J. Leukoc. Biol. 59: 775-783.
-
(1996)
J. Leukoc. Biol.
, vol.59
, pp. 775-783
-
-
McConkey, D.J.1
Orrenius, S.2
-
96
-
-
0025319665
-
Role of calcium ions in regulation of mammalian intramitochondrial metabolism
-
McCormack, J.G., Halestrap, A.P., and Denton, R.M. 1990. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70: 391-425.
-
(1990)
Physiol. Rev.
, vol.70
, pp. 391-425
-
-
McCormack, J.G.1
Halestrap, A.P.2
Denton, R.M.3
-
97
-
-
0037109064
-
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
-
McStay, G.P., Clarke, S.J., and Halestrap, A.P. 2002. Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. Biochem. J. 367: 541-548.
-
(2002)
Biochem. J.
, vol.367
, pp. 541-548
-
-
McStay, G.P.1
Clarke, S.J.2
Halestrap, A.P.3
-
98
-
-
0032535579
-
Light-induced photoactivation of hypericin affects the energy metabolism of human glioma cells by inhibiting hexokinase bound to mitochondria
-
Miccoli, L., Beurdeley-Thomas, A., De Pinieux, G., Sureau, F., Oudard, S., Dutrillaux, B., and Poupon, M.F. 1998. Light-induced photoactivation of hypericin affects the energy metabolism of human glioma cells by inhibiting hexokinase bound to mitochondria. Cancer Res. 58: 5777-5786.
-
(1998)
Cancer Res.
, vol.58
, pp. 5777-5786
-
-
Miccoli, L.1
Beurdeley-Thomas, A.2
De Pinieux, G.3
Sureau, F.4
Oudard, S.5
Dutrillaux, B.6
Poupon, M.F.7
-
99
-
-
0030892234
-
Apoptosis by death factor
-
Nagata, S. 1997. Apoptosis by death factor. Cell 88: 355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
100
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T., and Tsujimoto, Y. 2005. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434: 652-658.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
101
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
Narita, M., Shimizu, S., Ito, T., Chittenden, T., Lutz, R.J., Matsuda, H., and Tsujimoto, Y. 1998. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci. 95: 14681-14686.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chittenden, T.4
Lutz, R.J.5
Matsuda, H.6
Tsujimoto, Y.7
-
102
-
-
0033751426
-
Molecular mechanisms of ischemic neuronal injury
-
Neumar, R.W. 2000. Molecular mechanisms of ischemic neuronal injury. Ann. Emerg. Med. 36: 483-506.
-
(2000)
Ann. Emerg. Med.
, vol.36
, pp. 483-506
-
-
Neumar, R.W.1
-
103
-
-
0030051609
-
Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel
-
Nicolli, A., Basso, E., Petronilli, V., Wenger, R.M., and Bernardi, P. 1996. Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel. J. Biol. Chem. 271: 2185-2192.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2185-2192
-
-
Nicolli, A.1
Basso, E.2
Petronilli, V.3
Wenger, R.M.4
Bernardi, P.5
-
104
-
-
0033083559
-
Neuronal cell death: A demise with different shapes
-
Nicotera, P., Leist, M., and Manzo, L. 1999. Neuronal cell death: A demise with different shapes. Trends Pharmacol. Sci. 20: 46-51.
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 46-51
-
-
Nicotera, P.1
Leist, M.2
Manzo, L.3
-
105
-
-
0034903725
-
Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia
-
Nishimura, Y. and Lemasters, J.J. 2001. Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia. Cell Death Differ. 8: 850-858.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 850-858
-
-
Nishimura, Y.1
Lemasters, J.J.2
-
106
-
-
0035584857
-
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
-
Nordberg, J. and Arner, E.S. 2001. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31: 1287-1312.
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1287-1312
-
-
Nordberg, J.1
Arner, E.S.2
-
107
-
-
4344651318
-
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
-
Nylandsted, J., Gyrd-Hansen, M., Danielewicz, A., Fehrenbacher, N., Lademann, U., Hoyer-Hansen, M., Weber, E., Multhoff, G., Rohde, M., and Jaattela, M. 2004. Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J. Exp. Med. 200: 425-435.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 425-435
-
-
Nylandsted, J.1
Gyrd-Hansen, M.2
Danielewicz, A.3
Fehrenbacher, N.4
Lademann, U.5
Hoyer-Hansen, M.6
Weber, E.7
Multhoff, G.8
Rohde, M.9
Jaattela, M.10
-
108
-
-
0033844723
-
Astroglial trophic support and neuronal cell death: Influence of cellular energy level on type of cell death induced by mitochondrial toxin in cultured rat cortical neurons
-
Ohgoh, M., Shimizu, H., Ogura, H., and Nishizawa, Y. 2000. Astroglial trophic support and neuronal cell death: Influence of cellular energy level on type of cell death induced by mitochondrial toxin in cultured rat cortical neurons. J. Neurochem. 75: 925-933.
-
(2000)
J. Neurochem.
, vol.75
, pp. 925-933
-
-
Ohgoh, M.1
Shimizu, H.2
Ogura, H.3
Nishizawa, Y.4
-
109
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim, R.W. 1991. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14: 453-501.
-
(1991)
Annu. Rev. Neurosci.
, vol.14
, pp. 453-501
-
-
Oppenheim, R.W.1
-
110
-
-
0037376701
-
Cell death induced by acute renal injury: A perspective on the contributions of apoptosis and necrosis
-
Padanilam, B.J. 2003. Cell death induced by acute renal injury: A perspective on the contributions of apoptosis and necrosis. Am. J Physiol. Renal Physiol. 284: F608-F627.
-
(2003)
Am. J Physiol. Renal Physiol.
, vol.284
-
-
Padanilam, B.J.1
-
111
-
-
0032571294
-
The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
-
Pastorino, J.G., Chen, S.T., Tafani, M., Snyder, J.W., and Farber, J.L. 1998. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J. Biol. Chem. 273: 7770-7775.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7770-7775
-
-
Pastorino, J.G.1
Chen, S.T.2
Tafani, M.3
Snyder, J.W.4
Farber, J.L.5
-
112
-
-
22344443961
-
Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes
-
Perez-Morga, D., Vanhollebeke, B., Paturiaux-Hanocq, F., Nolan, D.P., Lins, L., Homble, F., Vanhamme, L., Tebabi, P., Pays, A., Poelvoorde, P., et al. 2005. Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science 309: 469-472.
-
(2005)
Science
, vol.309
, pp. 469-472
-
-
Perez-Morga, D.1
Vanhollebeke, B.2
Paturiaux-Hanocq, F.3
Nolan, D.P.4
Lins, L.5
Homble, F.6
Vanhamme, L.7
Tebabi, P.8
Pays, A.9
Poelvoorde, P.10
-
113
-
-
0035917865
-
Cooperation and competition in the evolution of ATP-producing pathways
-
Pfeiffer, T., Schuster, S., and Bonhoeffer, S. 2001. Cooperation and competition in the evolution of ATP-producing pathways. Science 292: 504-507.
-
(2001)
Science
, vol.292
, pp. 504-507
-
-
Pfeiffer, T.1
Schuster, S.2
Bonhoeffer, S.3
-
114
-
-
1242291784
-
Shigellosis: Innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development
-
Phalipon, A. and Sansonetti, P.J. 2003. Shigellosis: Innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development. Crit. Rev. Immunol. 23: 371-401.
-
(2003)
Crit. Rev. Immunol.
, vol.23
, pp. 371-401
-
-
Phalipon, A.1
Sansonetti, P.J.2
-
115
-
-
0036525842
-
Necrosis is an active and controlled form of programmed cell death
-
Proskuryakov, S.Y., Gabai, V.L., and Konoplyannikov, A.G. 2002. Necrosis is an active and controlled form of programmed cell death. Biochemistry 67: 387-408.
-
(2002)
Biochemistry
, vol.67
, pp. 387-408
-
-
Proskuryakov, S.Y.1
Gabai, V.L.2
Konoplyannikov, A.G.3
-
116
-
-
0023736226
-
Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system
-
Purves, D., Snider, W.D., and Voyvodic, J.T. 1988. Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system. Nature 336: 123-128.
-
(1988)
Nature
, vol.336
, pp. 123-128
-
-
Purves, D.1
Snider, W.D.2
Voyvodic, J.T.3
-
117
-
-
0022575011
-
A model for receptor-regulated calcium entry
-
Putney Jr., J.W. 1986. A model for receptor-regulated calcium entry. Cell Calcium 7: 1-12.
-
(1986)
Cell Calcium
, vol.7
, pp. 1-12
-
-
Putney Jr., J.W.1
-
118
-
-
0038725886
-
Ischemic neuronal death in the rat hippocampus: The calpain-calpastatin- caspase hypothesis
-
Rami, A. 2003. Ischemic neuronal death in the rat hippocampus: The calpain-calpastatin-caspase hypothesis. Neurobiol. Dis. 13: 75-88.
-
(2003)
Neurobiol. Dis.
, vol.13
, pp. 75-88
-
-
Rami, A.1
-
119
-
-
0033635249
-
In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability
-
Rathmell, J.C., Vander Heiden, M.G., Harris, M.H., Frauwirth, K.A., and Thompson, C.B. 2000. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol. Cell 6: 683-692.
-
(2000)
Mol. Cell
, vol.6
, pp. 683-692
-
-
Rathmell, J.C.1
Vander Heiden, M.G.2
Harris, M.H.3
Frauwirth, K.A.4
Thompson, C.B.5
-
120
-
-
0141863388
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
-
Rathmell, J.C., Fox, C.J., Plas, D.R., Hammerman, P.S., Cinalli, R.M., and Thompson, C.B. 2003. Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol. Cell. Biol. 23: 7315-7328.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
Hammerman, P.S.4
Cinalli, R.M.5
Thompson, C.B.6
-
122
-
-
0036732169
-
Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage
-
Reiners Jr., J.J., Caruso, J.A., Mathieu, P., Chelladurai, B., Yin, X.M., and Kessel, D. 2002. Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage. Cell Death Differ. 9: 934-944.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 934-944
-
-
Reiners Jr., J.J.1
Caruso, J.A.2
Mathieu, P.3
Chelladurai, B.4
Yin, X.M.5
Kessel, D.6
-
123
-
-
0041819685
-
Adenosine triphosphate is released during injurious mechanical ventilation and contributes to lung edema
-
Rich, P.B., Douillet, C.D., Mahler, S.A., Husain, S.A., and Boucher, R.C. 2003. Adenosine triphosphate is released during injurious mechanical ventilation and contributes to lung edema. J. Trauma 55: 290-297.
-
(2003)
J. Trauma
, vol.55
, pp. 290-297
-
-
Rich, P.B.1
Douillet, C.D.2
Mahler, S.A.3
Husain, S.A.4
Boucher, R.C.5
-
124
-
-
0031730496
-
Bcl-2 family members in the development and degenerative pathologies of the nervous system
-
Sadoul, R. 1998. Bcl-2 family members in the development and degenerative pathologies of the nervous system. Cell Death Differ. 5: 805-815.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 805-815
-
-
Sadoul, R.1
-
125
-
-
0034687837
-
Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F(0)F(1)-ATPase
-
Salomon, A.R., Voehringer, D.W., Herzenberg, L.A., and Khosla, C. 2000. Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F(0)F(1)-ATPase. Proc. Natl. Acad. Sci. 97: 14766-14771.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 14766-14771
-
-
Salomon, A.R.1
Voehringer, D.W.2
Herzenberg, L.A.3
Khosla, C.4
-
126
-
-
25444442603
-
A historical review of cellular calcium handling, with emphasis on mitochondria
-
Saris, N.E. and Carafoli, E. 2005. A historical review of cellular calcium handling, with emphasis on mitochondria. Biochemistry 70: 187-194.
-
(2005)
Biochemistry
, vol.70
, pp. 187-194
-
-
Saris, N.E.1
Carafoli, E.2
-
127
-
-
0035693680
-
Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death
-
Sattler, R. and Tymianski, M. 2001. Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death. Mol. Neurobiol. 24: 107-129.
-
(2001)
Mol. Neurobiol.
, vol.24
, pp. 107-129
-
-
Sattler, R.1
Tymianski, M.2
-
128
-
-
0034614897
-
Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
-
Sauter, B., Albert, M.L., Francisco, L., Larsson, M., Somersan, S., and Bhardwaj, N. 2000. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J. Exp. Med. 191: 423-434.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 423-434
-
-
Sauter, B.1
Albert, M.L.2
Francisco, L.3
Larsson, M.4
Somersan, S.5
Bhardwaj, N.6
-
129
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi, P., Misteli, T., and Bianchi, M.E. 2002. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418: 191-195.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
130
-
-
24744460273
-
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
-
Schinzel, A.C., Takeuchi, O., Huang, Z., Fisher, J.K., Zhou, Z., Rubens, J., Hetz, C., Danial, N.N., Moskowitz, M.A., and Korsmeyer, S.J. 2005. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc. Natl. Acad. Sci. 102: 12005-12010.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 12005-12010
-
-
Schinzel, A.C.1
Takeuchi, O.2
Huang, Z.3
Fisher, J.K.4
Zhou, Z.5
Rubens, J.6
Hetz, C.7
Danial, N.N.8
Moskowitz, M.A.9
Korsmeyer, S.J.10
-
131
-
-
0036477002
-
Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells
-
Shchepina, L.A., Popova, E.N., Pletjushkina, O.Y., and Chernyak, B.V. 2002. Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells. Biochemistry 67: 222-226.
-
(2002)
Biochemistry
, vol.67
, pp. 222-226
-
-
Shchepina, L.A.1
Popova, E.N.2
Pletjushkina, O.Y.3
Chernyak, B.V.4
-
132
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Shi, Y., Evans, J.E., and Rock, K.L. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-521.
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
133
-
-
0035500779
-
Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells
-
Somersan, S., Larsson, M., Fonteneau, J.F., Basu, S., Srivastava, P., and Bhardwaj, N. 2001. Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells. J. Immunol. 167: 4844-4852.
-
(2001)
J. Immunol.
, vol.167
, pp. 4844-4852
-
-
Somersan, S.1
Larsson, M.2
Fonteneau, J.F.3
Basu, S.4
Srivastava, P.5
Bhardwaj, N.6
-
134
-
-
0036932674
-
Shear-induced ATP release by cultured rabbit corneal epithelial cells
-
Srinivas, S.P., Mutharasan, R., and Fleiszig, S. 2002. Shear-induced ATP release by cultured rabbit corneal epithelial cells. Adv. Exp. Med. Biol. 506: 677-685.
-
(2002)
Adv. Exp. Med. Biol.
, vol.506
, pp. 677-685
-
-
Srinivas, S.P.1
Mutharasan, R.2
Fleiszig, S.3
-
135
-
-
0027201253
-
Mechanism of preconditioning. Ionic alterations
-
Steenbergen, C., Perlman, M.E., London, R.E., and Murphy, E. 1993. Mechanism of preconditioning. Ionic alterations. Circ. Res. 72: 112-125.
-
(1993)
Circ. Res.
, vol.72
, pp. 112-125
-
-
Steenbergen, C.1
Perlman, M.E.2
London, R.E.3
Murphy, E.4
-
136
-
-
0032150860
-
Glutamate-induced neuron death requires mitochondrial calcium uptake
-
Stout, A.K., Raphael, H.M., Kanterewicz, B.I., Klann, E., and Reynolds, I.J. 1998. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci. 1: 366-373.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 366-373
-
-
Stout, A.K.1
Raphael, H.M.2
Kanterewicz, B.I.3
Klann, E.4
Reynolds, I.J.5
-
137
-
-
1942421320
-
Calcium pumps of plasma membrane and cell interior
-
Strehler, E.E. and Treiman, M. 2004. Calcium pumps of plasma membrane and cell interior. Curr. Mol. Med. 4: 323-335.
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 323-335
-
-
Strehler, E.E.1
Treiman, M.2
-
138
-
-
0031839786
-
A novel aspect of calpain activation
-
Suzuki, K. and Sorimachi, H. 1998. A novel aspect of calpain activation. FEBS Lett. 433: 1-4.
-
(1998)
FEBS Lett.
, vol.433
, pp. 1-4
-
-
Suzuki, K.1
Sorimachi, H.2
-
139
-
-
0842328803
-
Structure, activation, and biology of calpain
-
Suzuki, K., Hata, S., Kawabata, Y., and Sorimachi, H. 2004. Structure, activation, and biology of calpain. Diabetes 53: S12-S18.
-
(2004)
Diabetes
, vol.53
-
-
Suzuki, K.1
Hata, S.2
Kawabata, Y.3
Sorimachi, H.4
-
140
-
-
0037206901
-
Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
-
Syntichaki, P., Xu, K., Driscoll, M., and Tavernarakis, N. 2002. Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans. Nature 419: 939-944.
-
(2002)
Nature
, vol.419
, pp. 939-944
-
-
Syntichaki, P.1
Xu, K.2
Driscoll, M.3
Tavernarakis, N.4
-
141
-
-
0035374621
-
Calcium is a key signaling molecule in β-lapachone-mediated cell death
-
Tagliarino, C., Pink, J.J., Dubyak, G.R., Nieminen, A.L., and Boothman, D.A. 2001. Calcium is a key signaling molecule in β-lapachone-mediated cell death. J. Biol. Chem. 276: 19150-19159.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19150-19159
-
-
Tagliarino, C.1
Pink, J.J.2
Dubyak, G.R.3
Nieminen, A.L.4
Boothman, D.A.5
-
142
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes
-
Thornberry, N.A., Bull, H.G., Calaycay, J.R., Chapman, K.T., Howard, A.D., Kostura, M.J., Miller, D.K., Molineaux, S.M., Weidner, J.R., Aunins, J., et al. 1992. A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes. Nature 356: 768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
143
-
-
0028944389
-
A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans
-
Treinin, M. and Chalfie, M. 1995. A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans. Neuron 14: 871-877.
-
(1995)
Neuron
, vol.14
, pp. 871-877
-
-
Treinin, M.1
Chalfie, M.2
-
144
-
-
0033999403
-
5-Aminolevulinic acid and its derivatives: Physical chemical properties and protoporphyrin IX formation in cultured cells
-
Uehlinger, P., Zellweger, M., Wagnieres, G., Juillerat-Jeanneret, L., van den Bergh, H., and Lange, N. 2000. 5-Aminolevulinic acid and its derivatives: Physical chemical properties and protoporphyrin IX formation in cultured cells. J. Photochem. Photobiol. B 54: 72-80.
-
(2000)
J. Photochem. Photobiol. B
, vol.54
, pp. 72-80
-
-
Uehlinger, P.1
Zellweger, M.2
Wagnieres, G.3
Juillerat-Jeanneret, L.4
Van Den Bergh, H.5
Lange, N.6
-
145
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen, D., Beyaert, R., Denecker, G., Goossens, V., Van Loo, G., Declercq, W., Grooten, J., Fiers, W., and Vandenabeele, P. 1998. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J. Exp. Med. 187: 1477-1485.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
146
-
-
15844415068
-
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans
-
Waldmann, R., Champigny, G., Voilley, N., Lauritzen, I., and Lazdunski, M. 1996. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J. Biol. Chem. 271: 10433-10436.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10433-10436
-
-
Waldmann, R.1
Champigny, G.2
Voilley, N.3
Lauritzen, I.4
Lazdunski, M.5
-
147
-
-
0033956278
-
Calpain and caspase: Can you tell the difference?
-
Wang, K.K. 2000. Calpain and caspase: Can you tell the difference? Trends Neurosci. 23: 20-26.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 20-26
-
-
Wang, K.K.1
-
148
-
-
0030984490
-
PARP is important for genomic stability but dispensable in apoptosis
-
Wang, Z.Q., Stingl, L., Morrison, C., Jantsch, M., Los, M., Schulze-Osthoff, K., and Wagner, E.F. 1997. PARP is important for genomic stability but dispensable in apoptosis. Genes & Dev. 11: 2347-2358.
-
(1997)
Genes & Dev.
, vol.11
, pp. 2347-2358
-
-
Wang, Z.Q.1
Stingl, L.2
Morrison, C.3
Jantsch, M.4
Los, M.5
Schulze-Osthoff, K.6
Wagner, E.F.7
-
149
-
-
11144338185
-
Redox active calcium ion channels and cell death
-
Waring, P. 2005. Redox active calcium ion channels and cell death. Arch. Biochem. Biophys. 434: 33-42.
-
(2005)
Arch. Biochem. Biophys.
, vol.434
, pp. 33-42
-
-
Waring, P.1
-
150
-
-
0029100890
-
Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis
-
Watson, A.J., Askew, J.N., and Benson, R.S. 1995. Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis. Gastroenterology 109: 472-482.
-
(1995)
Gastroenterology
, vol.109
, pp. 472-482
-
-
Watson, A.J.1
Askew, J.N.2
Benson, R.S.3
-
151
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei, M.C., Zong, W.X., Cheng, E.H., Lindsten, T., Panoutsakopoulou, V., Ross, A.J., Roth, K.A., MacGregor, G.R., Thompson, C.B., and Korsmeyer, S.J. 2001. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
152
-
-
0032724044
-
The induction of apoptosis by bacterial pathogens
-
Weinrauch, Y. and Zychlinsky, A. 1999. The induction of apoptosis by bacterial pathogens. Annu. Rev. Microbiol. 53: 155-187.
-
(1999)
Annu. Rev. Microbiol.
, vol.53
, pp. 155-187
-
-
Weinrauch, Y.1
Zychlinsky, A.2
-
153
-
-
0037042178
-
Photodynamic therapy of human breast cancer xenografts lacking caspase-3
-
Whitacre, C.M., Satoh, T.H., Xue, L., Gordon, N.H., and Oleinick, N.L. 2002. Photodynamic therapy of human breast cancer xenografts lacking caspase-3. Cancer Lett. 179: 43-49.
-
(2002)
Cancer Lett.
, vol.179
, pp. 43-49
-
-
Whitacre, C.M.1
Satoh, T.H.2
Xue, L.3
Gordon, N.H.4
Oleinick, N.L.5
-
154
-
-
0032963521
-
The toxicity of 6-hydroxydopamine on PC12 and P19 cells
-
Woodgate, A., MacGibbon, G., Walton, M., and Dragunow, M. 1999. The toxicity of 6-hydroxydopamine on PC12 and P19 cells. Brain Res. Mol. Brain Res. 69: 84-92.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.69
, pp. 84-92
-
-
Woodgate, A.1
MacGibbon, G.2
Walton, M.3
Dragunow, M.4
-
155
-
-
4544230902
-
Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels
-
Xiong, Z.G., Zhu, X.M., Chu, X.P., Minami, M., Hey, J., Wei, W.L., MacDonald, J.F., Wemmie, J.A., Price, M.P., Welsh, M.J., et al. 2004. Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels. Cell 118: 687-698.
-
(2004)
Cell
, vol.118
, pp. 687-698
-
-
Xiong, Z.G.1
Zhu, X.M.2
Chu, X.P.3
Minami, M.4
Hey, J.5
Wei, W.L.6
MacDonald, J.F.7
Wemmie, J.A.8
Price, M.P.9
Welsh, M.J.10
-
157
-
-
3342900223
-
2+-dependent proteases in ischemic neuronal death: A conserved 'calpain-cathepsin cascade' from nematodes to primates
-
2+-dependent proteases in ischemic neuronal death: A conserved 'calpain-cathepsin cascade' from nematodes to primates. Cell Calcium 36: 285-293.
-
(2004)
Cell Calcium
, vol.36
, pp. 285-293
-
-
Yamashima, T.1
-
158
-
-
2342595925
-
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a
-
Yermolaieva, O., Leonard, A.S., Schnizler, M.K., Abboud, F.M., and Welsh, M.J. 2004. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. Proc. Natl. Acad. Sci. 101: 6752-6757.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 6752-6757
-
-
Yermolaieva, O.1
Leonard, A.S.2
Schnizler, M.K.3
Abboud, F.M.4
Welsh, M.J.5
-
159
-
-
0041573041
-
NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
-
Ying, W., Garnier, P., and Swanson, R.A. 2003. NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem. Biophys. Res. Commun. 308: 809-813.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, pp. 809-813
-
-
Ying, W.1
Garnier, P.2
Swanson, R.A.3
-
160
-
-
12244267986
-
NAD+ as a metabolic link between DNA damage and cell death
-
Ying, W., Alano, C.C., Garnier, P., and Swanson, R.A. 2005. NAD+ as a metabolic link between DNA damage and cell death. J. Neurosci. Res. 79: 216-223.
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 216-223
-
-
Ying, W.1
Alano, C.C.2
Garnier, P.3
Swanson, R.A.4
-
161
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida, H., Kong, Y.Y., Yoshida, R., Elia, A.J., Hakem, A., Hakem, R., Penninger, J.M., and Mak, T.W. 1998. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94: 739-750.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
162
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu, S.W., Wang, H., Poitras, M.F., Coombs, C., Bowers, W.J., Federoff, H.J., Poirier, G.G., Dawson, T.M., and Dawson, V.L. 2002. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297: 259-263.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
163
-
-
0141884305
-
Diversity in the mechanisms of neuronal cell death
-
Yuan, J., Lipinski, M., and Degterev, A. 2003. Diversity in the mechanisms of neuronal cell death. Neuron 40: 401-413.
-
(2003)
Neuron
, vol.40
, pp. 401-413
-
-
Yuan, J.1
Lipinski, M.2
Degterev, A.3
-
164
-
-
11344282264
-
Addicted to death: Invasive cancer and the immune response to unscheduled cell death
-
Zeh III, H.J. and Lotze, M.T. 2005. Addicted to death: Invasive cancer and the immune response to unscheduled cell death. J. Immunother. 28: 1-9.
-
(2005)
J. Immunother.
, vol.28
, pp. 1-9
-
-
Zeh III, H.J.1
Lotze, M.T.2
-
165
-
-
14144256220
-
Role of macrophage apoptosis in the pathogenesis of Yersinia
-
Zhang, Y. and Bliska, J.B. 2005. Role of macrophage apoptosis in the pathogenesis of Yersinia. Curr. Top. Microbiol. Immunol. 289: 151-173.
-
(2005)
Curr. Top. Microbiol. Immunol.
, vol.289
, pp. 151-173
-
-
Zhang, Y.1
Bliska, J.B.2
-
166
-
-
3042597924
-
Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus
-
Zhou, Z., Yamamoto, Y., Sugai, F., Yoshida, K., Kishima, Y., Sumi, H., Nakamura, H., and Sakoda, S. 2004. Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus. J. Biol. Chem. 279: 27320-27326.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27320-27326
-
-
Zhou, Z.1
Yamamoto, Y.2
Sugai, F.3
Yoshida, K.4
Kishima, Y.5
Sumi, H.6
Nakamura, H.7
Sakoda, S.8
-
167
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong, W.X., Ditsworth, D., Bauer, D.E., Wang, Z.Q., and Thompson, C.B. 2004. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes & Dev. 18: 1272-1282.
-
(2004)
Genes & Dev.
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
-
168
-
-
0000098037
-
Direct measurement of free radical generation following reperfusion of ischemic myocardium
-
Zweier, J.L., Flaherty, J.T., and Weisfeldt, M.L. 1987. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc. Natl. Acad. Sci. 84: 1404-1407.
-
(1987)
Proc. Natl. Acad. Sci.
, vol.84
, pp. 1404-1407
-
-
Zweier, J.L.1
Flaherty, J.T.2
Weisfeldt, M.L.3
|