-
1
-
-
84992624274
-
-
International Agency for Research on Cancer (IARC). World Cancer Report 2014. Available online: http://publications.iarc.fr/Non-Series-Publications/World-Cancer-Reports/World-Cancer-Report-2014 (accessed on 5 August 2016).
-
(2016)
World Cancer Report 2014
-
-
-
2
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
[CrossRef] [PubMed]
-
Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 2007, 70, 461–477. [CrossRef] [PubMed]
-
(2007)
J. Nat. Prod
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
3
-
-
0035169066
-
The comprehensive approach to diet: A critical review
-
[PubMed]
-
Gerber, M. The comprehensive approach to diet: A critical review. J. Nutr. 2001, 131, 3051S–3055S. [PubMed]
-
(2001)
J. Nutr
, vol.131
, pp. 3051S-3055S
-
-
Gerber, M.1
-
4
-
-
0037248328
-
Cancer prevention—The potential for diet to modulate molecular signalling
-
[CrossRef]
-
Manson, M.M. Cancer prevention—The potential for diet to modulate molecular signalling. Trends Mol. Med. 2003, 9, 11–18. [CrossRef]
-
(2003)
Trends Mol. Med
, vol.9
, pp. 11-18
-
-
Manson, M.M.1
-
5
-
-
0033637140
-
The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
-
[PubMed]
-
Middleton, E.; Kandaswami, C.; Theoharides, T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 2000, 52, 673–751. [PubMed]
-
(2000)
Pharmacol. Rev
, vol.52
, pp. 673-751
-
-
Middleton, E.1
Kandaswami, C.2
Theoharides, T.C.3
-
6
-
-
84921288028
-
Variation in cancer risk among tissues can be explained by the number of stem cell divisions
-
[CrossRef] [PubMed]
-
Tomasetti, C.; Vogelstein, B. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 2015, 347, 78–81. [CrossRef] [PubMed]
-
(2015)
Science
, vol.347
, pp. 78-81
-
-
Tomasetti, C.1
Vogelstein, B.2
-
7
-
-
66849095259
-
Perspectives for cancer prevention with natural compounds
-
[CrossRef] [PubMed]
-
Amin, A.R.M.R.; Kucuk, O.; Khuri, F.R.; Shin, D.M. Perspectives for cancer prevention with natural compounds. J. Clin. Oncol. 2009, 27, 2712–2725. [CrossRef] [PubMed]
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 2712-2725
-
-
Amin, A.R.M.R.1
Kucuk, O.2
Khuri, F.R.3
Shin, D.M.4
-
8
-
-
77956016499
-
Cancer prevention with natural compounds
-
[CrossRef] [PubMed]
-
Gullett, N.P.; Ruhul Amin, A.R.; Bayraktar, S.; Pezzuto, J.M.; Shin, D.M.; Khuri, F.R.; Aggarwal, B.B.; Surh, Y.J.; Kucuk, O. Cancer prevention with natural compounds. Semin. Oncol. 2010, 37, 258–281. [CrossRef] [PubMed]
-
(2010)
Semin. Oncol
, vol.37
, pp. 258-281
-
-
Gullett, N.P.1
Ruhul Amin, A.R.2
Bayraktar, S.3
Pezzuto, J.M.4
Shin, D.M.5
Khuri, F.R.6
Aggarwal, B.B.7
Surh, Y.J.8
Kucuk, O.9
-
9
-
-
0035527471
-
Molecular targets for nutrients involved with cancer prevention
-
Milner, J.A.; McDonald, S.S.; Anderson, D.E.; Greenwald, P. Molecular targets for nutrients involved with cancer prevention. Nutr. Cancer Int. J. 2001, 41, 1–16.
-
(2001)
Nutr. Cancer Int. J
, vol.41
, pp. 1-16
-
-
Milner, J.A.1
McDonald, S.S.2
Anderson, D.E.3
Greenwald, P.4
-
10
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh, Y.J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 2003, 3, 768–780.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
11
-
-
84893625419
-
Cranberry and recurrent cystitis: More than marketing?
-
Micali, S.; Isgro, G.; Bianchi, G.; Miceli, N.; Calapai, G.; Navarra, M. Cranberry and recurrent cystitis: More than marketing? Crit. Rev. Food Sci. Nutr. 2014, 54, 1063–1075.
-
(2014)
Crit. Rev. Food Sci. Nutr
, vol.54
, pp. 1063-1075
-
-
Micali, S.1
Isgro, G.2
Bianchi, G.3
Miceli, N.4
Calapai, G.5
Navarra, M.6
-
12
-
-
84920550548
-
Neuroprotection by association of palmitoylethanolamide with luteolin in experimental alzheimer’s disease models: The control of neuroinflammation
-
Paterniti, I.; Cordaro, M.; Campolo, M.; Siracusa, R.; Cornelius, C.; Navarra, M.; Cuzzocrea, S.; Esposito, E. Neuroprotection by association of palmitoylethanolamide with luteolin in experimental alzheimer’s disease models: The control of neuroinflammation. CNS Neurol. Disord. Drug Targets 2014, 13, 1530–1541.
-
(2014)
CNS Neurol. Disord. Drug Targets
, vol.13
, pp. 1530-1541
-
-
Paterniti, I.1
Cordaro, M.2
Campolo, M.3
Siracusa, R.4
Cornelius, C.5
Navarra, M.6
Cuzzocrea, S.7
Esposito, E.8
-
13
-
-
31444437481
-
Flavonoid composition of fruit tissues of citrus species
-
Nogata, Y.; Sakamoto, K.; Shiratsuchi, H.; Ishii, T.; Yano, M.; Ohta, H. Flavonoid composition of fruit tissues of citrus species. Biosci. Biotechnol. Biochem. 2006, 70, 178–192.
-
(2006)
Biosci. Biotechnol. Biochem
, vol.70
, pp. 178-192
-
-
Nogata, Y.1
Sakamoto, K.2
Shiratsuchi, H.3
Ishii, T.4
Yano, M.5
Ohta, H.6
-
14
-
-
50449111165
-
Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity
-
Benavente-Garcia, O.; Castillo, J. Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity. J. Agric. Food Chem. 2008, 56, 6185–6205.
-
(2008)
J. Agric. Food Chem
, vol.56
, pp. 6185-6205
-
-
Benavente-Garcia, O.1
Castillo, J.2
-
15
-
-
0035904858
-
Flavonoids: Structural requirements for antiproliferative activity on breast cancer cells
-
Pouget, C.; Lauthier, F.; Simon, A.; Fagnere, C.; Basly, J.P.; Delage, C.; Chulia, A.J. Flavonoids: Structural requirements for antiproliferative activity on breast cancer cells. Bioorg. Med. Chem. Lett. 2001, 11, 3095–3097.
-
(2001)
Bioorg. Med. Chem. Lett
, vol.11
, pp. 3095-3097
-
-
Pouget, C.1
Lauthier, F.2
Simon, A.3
Fagnere, C.4
Basly, J.P.5
Delage, C.6
Chulia, A.J.7
-
16
-
-
8444228130
-
Cytotoxicity and antiproliferative activities of several phenolic compounds against three melanocytes cell lines: Relationship between structure and activity
-
Yanez, J.; Vicente, V.; Alcaraz, M.; Castillo, J.; Benavente-Garcia, O.; Canteras, M.; Teruel, J.A.L. Cytotoxicity and antiproliferative activities of several phenolic compounds against three melanocytes cell lines: Relationship between structure and activity. Nutr. Cancer Int. J. 2004, 49, 191–199.
-
(2004)
Nutr. Cancer Int. J
, vol.49
, pp. 191-199
-
-
Yanez, J.1
Vicente, V.2
Alcaraz, M.3
Castillo, J.4
Benavente-Garcia, O.5
Canteras, M.6
Teruel, J.A.L.7
-
17
-
-
0036251941
-
Effects of several flavonoids on the growth of B16F10 and SK-MEL-1 melanoma cell lines: Relationship between structure and activity
-
Rodriguez, J.; Yanez, J.; Vicente, V.; Alcaraz, M.; Benavente-Garcia, O.; Castillo, J.; Lorente, J.; Lozano, J.A. Effects of several flavonoids on the growth of B16F10 and SK-MEL-1 melanoma cell lines: Relationship between structure and activity. Melanoma Res. 2002, 12, 99–107.
-
(2002)
Melanoma Res
, vol.12
, pp. 99-107
-
-
Rodriguez, J.1
Yanez, J.2
Vicente, V.3
Alcaraz, M.4
Benavente-Garcia, O.5
Castillo, J.6
Lorente, J.7
Lozano, J.A.8
-
18
-
-
0037331336
-
Effects of several polyhydroxylated flavonoids on the growth of B16F10 melanoma and melan-a melanocyte cell lines: Influence of the sequential oxidation state of the flavonoid skeleton
-
Martinez, C.; Yanez, J.; Vicente, V.; Alcaraz, M.; Benavente-Garcia, O.; Castillo, J.; Lorente, J.; Lozano, J.A. Effects of several polyhydroxylated flavonoids on the growth of B16F10 melanoma and melan-a melanocyte cell lines: Influence of the sequential oxidation state of the flavonoid skeleton. Melanoma Res. 2003, 13, 3–9.
-
(2003)
Melanoma Res
, vol.13
, pp. 3-9
-
-
Martinez, C.1
Yanez, J.2
Vicente, V.3
Alcaraz, M.4
Benavente-Garcia, O.5
Castillo, J.6
Lorente, J.7
Lozano, J.A.8
-
19
-
-
33646711437
-
Nutrition and cancer prevention: Targets, strategies, and the importance of early life interventions
-
San Francisco, CA, USA, 24–28 May 2005; Lucas, A., Sampson, H.A., Eds.; Nestec Ltd.: Basel, Switzerland
-
Hursting, S.D.; Cantwell, M.M.; Sansbury, L.B.; Forman, M.R. Nutrition and cancer prevention: Targets, strategies, and the importance of early life interventions. In Proceedings of the 57th Nestlé Nutrition Workshop, Pediatric Program, Half Moon Bay, San Francisco, CA, USA, 24–28 May 2005; Lucas, A., Sampson, H.A., Eds.; Nestec Ltd.: Basel, Switzerland, 2006; pp. 153–202.
-
(2006)
Proceedings of the 57Th Nestlé Nutrition Workshop, Pediatric Program, Half Moon Bay
, pp. 153-202
-
-
Hursting, S.D.1
Cantwell, M.M.2
Sansbury, L.B.3
Forman, M.R.4
-
20
-
-
70350337093
-
Vitamin C: Update on physiology and pharmacology
-
Mandl, J.; Szarka, A.; Banhegyi, G. Vitamin C: Update on physiology and pharmacology. Br. J. Pharmacol. 2009, 157, 1097–1110.
-
(2009)
Br. J. Pharmacol
, vol.157
, pp. 1097-1110
-
-
Mandl, J.1
Szarka, A.2
Banhegyi, G.3
-
21
-
-
1542605222
-
Flavonoids: Antioxidants or signalling molecules?
-
Williams, R.J.; Spencer, J.P.; Rice-Evans, C. Flavonoids: Antioxidants or signalling molecules? Free Radic. Biol. Med. 2004, 36, 838–849.
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 838-849
-
-
Williams, R.J.1
Spencer, J.P.2
Rice-Evans, C.3
-
22
-
-
0035001464
-
Biological properties of citrus flavonoids pertaining to cancer and inflammation
-
Manthey, J.A.; Grohmann, K.; Guthrie, N. Biological properties of citrus flavonoids pertaining to cancer and inflammation. Curr. Med. Chem. 2001, 8, 135–153.
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 135-153
-
-
Manthey, J.A.1
Grohmann, K.2
Guthrie, N.3
-
23
-
-
0038293482
-
Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not
-
Nyberg, F.; Hou, S.M.; Pershagen, G.; Lambert, B. Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not. Carcinogenesis 2003, 24, 689–696.
-
(2003)
Carcinogenesis
, vol.24
, pp. 689-696
-
-
Nyberg, F.1
Hou, S.M.2
Pershagen, G.3
Lambert, B.4
-
24
-
-
0030014804
-
Inhibition of bacterial mutagenesis by citrus flavonoids
-
Calomme, M.; Pieters, L.; Vlietinck, A.; Vanden Berghe, D. Inhibition of bacterial mutagenesis by citrus flavonoids. Planta Med. 1996, 62, 222–226.
-
(1996)
Planta Med
, vol.62
, pp. 222-226
-
-
Calomme, M.1
Pieters, L.2
Vlietinck, A.3
Vanden Berghe, D.4
-
25
-
-
0028518884
-
Protection from UV-B-induced DNA damage by flavonoids
-
Kootstra, A. Protection from UV-B-induced DNA damage by flavonoids. Plant Mol. Biol. 1994, 26, 771–774.
-
(1994)
Plant Mol. Biol
, vol.26
, pp. 771-774
-
-
Kootstra, A.1
-
26
-
-
81055156809
-
Quercetin protects human-derived liver cells against mercury-induced DNA-damage and alterations of the redox status
-
Barcelos, G.R.; Angeli, J.P.; Serpeloni, J.M.; Grotto, D.; Rocha, B.A.; Bastos, J.K.; Knasmuller, S.; Junior, F.B. Quercetin protects human-derived liver cells against mercury-induced DNA-damage and alterations of the redox status. Mutat. Res. 2011, 726, 109–115.
-
(2011)
Mutat. Res
, vol.726
, pp. 109-115
-
-
Barcelos, G.R.1
Angeli, J.P.2
Serpeloni, J.M.3
Grotto, D.4
Rocha, B.A.5
Bastos, J.K.6
Knasmuller, S.7
Junior, F.B.8
-
27
-
-
30544433019
-
The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells
-
Gao, K.; Henning, S.M.; Niu, Y.T.; Youssefian, A.A.; Seeram, N.P.; Xu, A.L.; Heber, D. The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells. J. Nutr. Biochem. 2006, 17, 89–95.
-
(2006)
J. Nutr. Biochem
, vol.17
, pp. 89-95
-
-
Gao, K.1
Henning, S.M.2
Niu, Y.T.3
Youssefian, A.A.4
Seeram, N.P.5
Xu, A.L.6
Heber, D.7
-
28
-
-
84877064248
-
Inhibitory effect of naringenin (Citrus flavonone) on N-nitrosodiethylamine induced hepatocarcinogenesis in rats
-
Arul, D.; Subramanian, P. Inhibitory effect of naringenin (Citrus flavonone) on N-nitrosodiethylamine induced hepatocarcinogenesis in rats. Biochem. Biophys. Res. Commun. 2013, 434, 203–209.
-
(2013)
Biochem. Biophys. Res. Commun
, vol.434
, pp. 203-209
-
-
Arul, D.1
Subramanian, P.2
-
29
-
-
84880332738
-
Attenuation of ndea-induced hepatocarcinogenesis by naringenin in rats
-
Subramanian, P.; Arul, D. Attenuation of ndea-induced hepatocarcinogenesis by naringenin in rats. Cell Biochem. Funct. 2013, 31, 511–517.
-
(2013)
Cell Biochem. Funct
, vol.31
, pp. 511-517
-
-
Subramanian, P.1
Arul, D.2
-
30
-
-
0035451796
-
Inhibitory effect of naringin on the micronuclei induced by ifosfamide in mouse, and evaluation of its modulatory effect on the CYP3A subfamily
-
Alvarez-Gonzalez, I.; Madrigal-Bujaidar, E.; Dorado, V.; Espinosa-Aguirre, J.J. Inhibitory effect of naringin on the micronuclei induced by ifosfamide in mouse, and evaluation of its modulatory effect on the CYP3A subfamily. Mutat. Res. 2001, 480, 171–178.
-
(2001)
Mutat. Res
, vol.480
, pp. 171-178
-
-
Alvarez-Gonzalez, I.1
Madrigal-Bujaidar, E.2
Dorado, V.3
Espinosa-Aguirre, J.J.4
-
31
-
-
77950899273
-
Effect of naringin on the DNA damage induced by daunorubicin in mouse hepatocytes and cardiocytes
-
Carino-Cortes, R.; Alvarez-Gonzalez, I.; Martino-Roaro, L.; Madrigal-Bujaidar, E. Effect of naringin on the DNA damage induced by daunorubicin in mouse hepatocytes and cardiocytes. Biol. Pharm. Bull. 2010, 33, 697–701.
-
(2010)
Biol. Pharm. Bull
, vol.33
, pp. 697-701
-
-
Carino-Cortes, R.1
Alvarez-Gonzalez, I.2
Martino-Roaro, L.3
Madrigal-Bujaidar, E.4
-
32
-
-
84890708093
-
Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis
-
Sequetto, P.L.; Oliveira, T.T.; Maldonado, I.R.; Augusto, L.E.; Mello, V.J.; Pizziolo, V.R.; Almeida, M.R.; Silva, M.E.; Novaes, R.D. Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis. Food Chem. Toxicol. 2014, 64, 200–209.
-
(2014)
Food Chem. Toxicol
, vol.64
, pp. 200-209
-
-
Sequetto, P.L.1
Oliveira, T.T.2
Maldonado, I.R.3
Augusto, L.E.4
Mello, V.J.5
Pizziolo, V.R.6
Almeida, M.R.7
Silva, M.E.8
Novaes, R.D.9
-
33
-
-
45749118021
-
Chemoprotective effects of hesperidin against genotoxicity induced by cyclophosphamide in mice bone marrow cells
-
Ahmadi, A.; Hosseinimehr, S.J.; Naghshvar, F.; Hajir, E.; Ghahremani, M. Chemoprotective effects of hesperidin against genotoxicity induced by cyclophosphamide in mice bone marrow cells. Arch. Pharm. Res. 2008, 31, 794–797.
-
(2008)
Arch. Pharm. Res
, vol.31
, pp. 794-797
-
-
Ahmadi, A.1
Hosseinimehr, S.J.2
Naghshvar, F.3
Hajir, E.4
Ghahremani, M.5
-
34
-
-
0028420282
-
Antimutagenic effect of plant flavonoids in the salmonella assay system
-
Choi, J.S.; Park, K.Y.; Moon, S.H.; Rhee, S.H.; Young, H.S. Antimutagenic effect of plant flavonoids in the salmonella assay system. Arch. Pharm. Res. 1994, 17, 71–75.
-
(1994)
Arch. Pharm. Res
, vol.17
, pp. 71-75
-
-
Choi, J.S.1
Park, K.Y.2
Moon, S.H.3
Rhee, S.H.4
Young, H.S.5
-
35
-
-
0031915796
-
Molecular basis of the inhibition of human aromatase (Estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study
-
Kao, Y.C.; Zhou, C.; Sherman, M.; Laughton, C.A.; Chen, S. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study. Environ. Health Perspect. 1998, 106, 85–92.
-
(1998)
Environ. Health Perspect
, vol.106
, pp. 85-92
-
-
Kao, Y.C.1
Zhou, C.2
Sherman, M.3
Laughton, C.A.4
Chen, S.5
-
36
-
-
1942472986
-
Phytoestrogens are potent inhibitors of estrogen sulfation: Implications for breast cancer risk and treatment
-
Harris, R.M.; Wood, D.M.; Bottomley, L.; Blagg, S.; Owen, K.; Hughes, P.J.; Waring, R.H.; Kirk, C.J. Phytoestrogens are potent inhibitors of estrogen sulfation: Implications for breast cancer risk and treatment. J. Clin. Endocrinol. Metab. 2004, 89, 1779–1787.
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, pp. 1779-1787
-
-
Harris, R.M.1
Wood, D.M.2
Bottomley, L.3
Blagg, S.4
Owen, K.5
Hughes, P.J.6
Waring, R.H.7
Kirk, C.J.8
-
37
-
-
0033636087
-
Effects of Citrus flavonoids on the mutagenicity of heterocyclic amines and on cytochrome P450 1A2 activity
-
Bear, W.L.; Teel, R.W. Effects of Citrus flavonoids on the mutagenicity of heterocyclic amines and on cytochrome P450 1A2 activity. Anticancer Res. 2000, 20, 3609–3614.
-
(2000)
Anticancer Res
, vol.20
, pp. 3609-3614
-
-
Bear, W.L.1
Teel, R.W.2
-
38
-
-
0242610804
-
The chemopreventive bioflavonoid apigenin modulates signal transduction pathways in keratinocyte and colon carcinoma cell lines
-
Van Dross, R.; Xue, Y.; Knudson, A.; Pelling, J.C. The chemopreventive bioflavonoid apigenin modulates signal transduction pathways in keratinocyte and colon carcinoma cell lines. J. Nutr. 2003, 133, 3800S–3804S.
-
(2003)
J. Nutr
, vol.133
, pp. 3800S-3804S
-
-
Van Dross, R.1
Xue, Y.2
Knudson, A.3
Pelling, J.C.4
-
39
-
-
33846002359
-
Inhibitory effect of apigenin on benzo(A)pyrene-mediated genotoxicity in swiss albino mice
-
Khan, T.H.; Jahangir, T.; Prasad, L.; Sultana, S. Inhibitory effect of apigenin on benzo(a)pyrene-mediated genotoxicity in swiss albino mice. J. Pharm. Pharmacol. 2006, 58, 1655–1660.
-
(2006)
J. Pharm. Pharmacol
, vol.58
, pp. 1655-1660
-
-
Khan, T.H.1
Jahangir, T.2
Prasad, L.3
Sultana, S.4
-
40
-
-
0036489186
-
Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter
-
Myhrstad, M.C.; Carlsen, H.; Nordstrom, O.; Blomhoff, R.; Moskaug, J.O. Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter. Free Radic. Biol. Med. 2002, 32, 386–393.
-
(2002)
Free Radic. Biol. Med
, vol.32
, pp. 386-393
-
-
Myhrstad, M.C.1
Carlsen, H.2
Nordstrom, O.3
Blomhoff, R.4
Moskaug, J.O.5
-
41
-
-
0025176844
-
Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice
-
Wei, H.; Tye, L.; Bresnick, E.; Birt, D.F. Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice. Cancer Res. 1990, 50, 499–502.
-
(1990)
Cancer Res
, vol.50
, pp. 499-502
-
-
Wei, H.1
Tye, L.2
Bresnick, E.3
Birt, D.F.4
-
42
-
-
0031057115
-
Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid
-
Birt, D.F.; Mitchell, D.; Gold, B.; Pour, P.; Pinch, H.C. Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid. Anticancer Res. 1997, 17, 85–91.
-
(1997)
Anticancer Res
, vol.17
, pp. 85-91
-
-
Birt, D.F.1
Mitchell, D.2
Gold, B.3
Pour, P.4
Pinch, H.C.5
-
43
-
-
77953192767
-
Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats
-
Leonardi, T.; Vanamala, J.; Taddeo, S.S.; Davidson, L.A.; Murphy, M.E.; Patil, B.S.; Wang, N.; Carroll, R.J.; Chapkin, R.S.; Lupton, J.R.; et al. Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats. Exp. Biol. Med. (Maywood) 2010, 235, 710–717.
-
(2010)
Exp. Biol. Med. (Maywood)
, vol.235
, pp. 710-717
-
-
Leonardi, T.1
Vanamala, J.2
Taddeo, S.S.3
Davidson, L.A.4
Murphy, M.E.5
Patil, B.S.6
Wang, N.7
Carroll, R.J.8
Chapkin, R.S.9
Lupton, J.R.10
-
44
-
-
83455210585
-
Hesperidin protects renal and hepatic tissues against free radical-mediated oxidative stress during DMBA-induced experimental breast cancer
-
Nandakumar, N.; Balasubramanian, M.P. Hesperidin protects renal and hepatic tissues against free radical-mediated oxidative stress during DMBA-induced experimental breast cancer. J. Environ. Pathol. Toxicol. Oncol. 2011, 30, 283–300.
-
(2011)
J. Environ. Pathol. Toxicol. Oncol
, vol.30
, pp. 283-300
-
-
Nandakumar, N.1
Balasubramanian, M.P.2
-
45
-
-
67349197661
-
Modulatory efficacy of hesperetin (Citrus flavanone) on xenobiotic-metabolizing enzymes during 1,2-dimethylhydrazine-induced colon carcinogenesis
-
Aranganathan, S.; Selvam, J.P.; Sangeetha, N.; Nalini, N. Modulatory efficacy of hesperetin (Citrus flavanone) on xenobiotic-metabolizing enzymes during 1,2-dimethylhydrazine-induced colon carcinogenesis. Chem. Biol. Interact. 2009, 180, 254–261.
-
(2009)
Chem. Biol. Interact
, vol.180
, pp. 254-261
-
-
Aranganathan, S.1
Selvam, J.P.2
Sangeetha, N.3
Nalini, N.4
-
46
-
-
84894085354
-
Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7,12-dimethylbenz(A)anthracene induced mammary carcinoma in experimental rats
-
Lakshmi, A.; Subramanian, S. Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7,12-dimethylbenz(a)anthracene induced mammary carcinoma in experimental rats. Biochimie 2014, 99, 96–109.
-
(2014)
Biochimie
, vol.99
, pp. 96-109
-
-
Lakshmi, A.1
Subramanian, S.2
-
47
-
-
0034665123
-
Inhibitory effect of Citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice
-
Murakami, A.; Nakamura, Y.; Torikai, K.; Tanaka, T.; Koshiba, T.; Koshimizu, K.; Kuwahara, S.; Takahashi, Y.; Ogawa, K.; Yano, M.; et al. Inhibitory effect of Citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice. Cancer Res. 2000, 60, 5059–5066.
-
(2000)
Cancer Res
, vol.60
, pp. 5059-5066
-
-
Murakami, A.1
Nakamura, Y.2
Torikai, K.3
Tanaka, T.4
Koshiba, T.5
Koshimizu, K.6
Kuwahara, S.7
Takahashi, Y.8
Ogawa, K.9
Yano, M.10
-
48
-
-
0025980543
-
Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro
-
Kandaswami, C.; Perkins, E.; Soloniuk, D.S.; Drzewiecki, G.; Middleton, E., Jr. Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro. Cancer Lett. 1991, 56, 147–152.
-
(1991)
Cancer Lett
, vol.56
, pp. 147-152
-
-
Kandaswami, C.1
Perkins, E.2
Soloniuk, D.S.3
Drzewiecki, G.4
Middleton, E.5
-
49
-
-
0027322565
-
Studies on the differentiation inducers of myeloid leukemic cells from Citrus species
-
Sugiyama, S.; Umehara, K.; Kuroyanagi, M.; Ueno, A.; Taki, T. Studies on the differentiation inducers of myeloid leukemic cells from Citrus species. Chem. Pharm. Bull. (Tokyo) 1993, 41, 714–719.
-
(1993)
Chem. Pharm. Bull. (Tokyo)
, vol.41
, pp. 714-719
-
-
Sugiyama, S.1
Umehara, K.2
Kuroyanagi, M.3
Ueno, A.4
Taki, T.5
-
50
-
-
0029597877
-
Citrus flavone tangeretin inhibits leukaemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes
-
Hirano, T.; Abe, K.; Gotoh, M.; Oka, K. Citrus flavone tangeretin inhibits leukaemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes. Br. J. Cancer 1995, 72, 1380–1388.
-
(1995)
Br. J. Cancer
, vol.72
, pp. 1380-1388
-
-
Hirano, T.1
Abe, K.2
Gotoh, M.3
Oka, K.4
-
51
-
-
34247137191
-
Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells
-
Morley, K.L.; Ferguson, P.J.; Koropatnick, J. Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett. 2007, 251, 168–178.
-
(2007)
Cancer Lett
, vol.251
, pp. 168-178
-
-
Morley, K.L.1
Ferguson, P.J.2
Koropatnick, J.3
-
52
-
-
0036799151
-
Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating cdk inhibitors p21 and p27 in human colorectal carcinoma cells
-
Pan, M.H.; Chen, W.J.; Lin-Shiau, S.Y.; Ho, C.T.; Lin, J.K. Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating cdk inhibitors p21 and p27 in human colorectal carcinoma cells. Carcinogenesis 2002, 23, 1677–1684.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1677-1684
-
-
Pan, M.H.1
Chen, W.J.2
Lin-Shiau, S.Y.3
Ho, C.T.4
Lin, J.K.5
-
53
-
-
4344618973
-
Anti-tumour effects of nobiletin, a Citrus flavonoid, on gastric cancer include: Antiproliferative effects, induction of apoptosis and cell cycle deregulation
-
Yoshimizu, N.; Otani, Y.; Saikawa, Y.; Kubota, T.; Yoshida, M.; Furukawa, T.; Kumai, K.; Kameyama, K.; Fujii, M.; Yano, M.; et al. Anti-tumour effects of nobiletin, a Citrus flavonoid, on gastric cancer include: Antiproliferative effects, induction of apoptosis and cell cycle deregulation. Aliment. Pharmacol. Ther. 2004, 20 (Suppl. 1), 95–101.
-
(2004)
Aliment. Pharmacol. Ther
, vol.20
, pp. 95-101
-
-
Yoshimizu, N.1
Otani, Y.2
Saikawa, Y.3
Kubota, T.4
Yoshida, M.5
Furukawa, T.6
Kumai, K.7
Kameyama, K.8
Fujii, M.9
Yano, M.10
-
54
-
-
34248228116
-
Chemopreventive effects of orange peel extract (OPE) I: Ope inhibits intestinal tumor growth in Apc(min/+) mice
-
Fan, K.; Kurihara, N.; Abe, S.; Ho, C.T.; Ghai, G.; Yang, K. Chemopreventive effects of orange peel extract (OPE) I: Ope inhibits intestinal tumor growth in Apc(min/+) mice. J. Med. Food 2007, 10, 11–17.
-
(2007)
J. Med. Food
, vol.10
, pp. 11-17
-
-
Fan, K.1
Kurihara, N.2
Abe, S.3
Ho, C.T.4
Ghai, G.5
Yang, K.6
-
55
-
-
34248160425
-
Chemopreventive effects of orange peel extract (OPE) II: OPE inhibits atypical hyperplastic lesions in rodent mammary gland
-
Abe, S.; Fan, K.; Ho, C.T.; Ghai, G.; Yang, K. Chemopreventive effects of orange peel extract (OPE) II: OPE inhibits atypical hyperplastic lesions in rodent mammary gland. J. Med. Food 2007, 10, 18–24.
-
(2007)
J. Med. Food
, vol.10
, pp. 18-24
-
-
Abe, S.1
Fan, K.2
Ho, C.T.3
Ghai, G.4
Yang, K.5
-
56
-
-
20044383933
-
Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation
-
Van Slambrouck, S.; Parmar, V.S.; Sharma, S.K.; de Bondt, B.; Fore, F.; Coopman, P.; Vanhoecke, B.W.; Boterberg, T.; Depypere, H.T.; Leclercq, G.; et al. Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation. FEBS Lett. 2005, 579, 1665–1669.
-
(2005)
FEBS Lett
, vol.579
, pp. 1665-1669
-
-
Van Slambrouck, S.1
Parmar, V.S.2
Sharma, S.K.3
De Bondt, B.4
Fore, F.5
Coopman, P.6
Vanhoecke, B.W.7
Boterberg, T.8
Depypere, H.T.9
Leclercq, G.10
-
57
-
-
40949149451
-
Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells
-
Akao, Y.; Itoh, T.; Ohguchi, K.; Iinuma, M.; Nozawa, Y. Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells. Bioorg. Med. Chem. 2008, 16, 2803–2810.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 2803-2810
-
-
Akao, Y.1
Itoh, T.2
Ohguchi, K.3
Iinuma, M.4
Nozawa, Y.5
-
58
-
-
0035070354
-
Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro
-
Rooprai, H.K.; Kandanearatchi, A.; Maidment, S.L.; Christidou, M.; Trillo-Pazos, G.; Dexter, D.T.; Rucklidge, G.J.; Widmer, W.; Pilkington, G.J. Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro. Neuropathol. Appl. Neurobiol. 2001, 27, 29–39.
-
(2001)
Neuropathol. Appl. Neurobiol
, vol.27
, pp. 29-39
-
-
Rooprai, H.K.1
Kandanearatchi, A.2
Maidment, S.L.3
Christidou, M.4
Trillo-Pazos, G.5
Dexter, D.T.6
Rucklidge, G.J.7
Widmer, W.8
Pilkington, G.J.9
-
59
-
-
71549170831
-
Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway
-
Arafa el, S.A.; Zhu, Q.; Barakat, B.M.; Wani, G.; Zhao, Q.; El-Mahdy, M.A.; Wani, A.A. Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway. Cancer Res. 2009, 69, 8910–8917.
-
(2009)
Cancer Res
, vol.69
, pp. 8910-8917
-
-
Arafa El, S.A.1
Zhu, Q.2
Barakat, B.M.3
Wani, G.4
Zhao, Q.5
El-Mahdy, M.A.6
Wani, A.A.7
-
60
-
-
84908145653
-
Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways
-
Dong, Y.; Cao, A.L.; Shi, J.R.; Yin, P.H.; Wang, L.; Ji, G.; Xie, J.Q.; Wu, D.Z. Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. Oncol. Rep. 2014, 31, 1788–1794.
-
(2014)
Oncol. Rep
, vol.31
, pp. 1788-1794
-
-
Dong, Y.1
Cao, A.L.2
Shi, J.R.3
Yin, P.H.4
Wang, L.5
Ji, G.6
Xie, J.Q.7
Wu, D.Z.8
-
61
-
-
34147146571
-
Protective effects of Citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells
-
Tang, M.; Ogawa, K.; Asamoto, M.; Hokaiwado, N.; Seeni, A.; Suzuki, S.; Takahashi, S.; Tanaka, T.; Ichikawa, K.; Shirai, T. Protective effects of Citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. Cancer Sci. 2007, 98, 471–477.
-
(2007)
Cancer Sci
, vol.98
, pp. 471-477
-
-
Tang, M.1
Ogawa, K.2
Asamoto, M.3
Hokaiwado, N.4
Seeni, A.5
Suzuki, S.6
Takahashi, S.7
Tanaka, T.8
Ichikawa, K.9
Shirai, T.10
-
62
-
-
79951884253
-
Effects of nobiletin on PhIP-induced prostate and colon carcinogenesis in F344 rats
-
Tang, M.X.; Ogawa, K.; Asamoto, M.; Chewonarin, T.; Suzuki, S.; Tanaka, T.; Shirai, T. Effects of nobiletin on PhIP-induced prostate and colon carcinogenesis in F344 rats. Nutr. Cancer 2011, 63, 227–233.
-
(2011)
Nutr. Cancer
, vol.63
, pp. 227-233
-
-
Tang, M.X.1
Ogawa, K.2
Asamoto, M.3
Chewonarin, T.4
Suzuki, S.5
Tanaka, T.6
Shirai, T.7
-
63
-
-
21644461801
-
Citrus nobiletin inhibits azoxymethane-induced large bowel carcinogenesis in rats
-
Suzuki, R.; Kohno, H.; Murakami, A.; Koshimizu, K.; Ohigashi, H.; Yano, M.; Tokuda, H.; Nishino, H.; Tanaka, T. Citrus nobiletin inhibits azoxymethane-induced large bowel carcinogenesis in rats. Biofactors 2004, 22, 111–114.
-
(2004)
Biofactors
, vol.22
, pp. 111-114
-
-
Suzuki, R.1
Kohno, H.2
Murakami, A.3
Koshimizu, K.4
Ohigashi, H.5
Yano, M.6
Tokuda, H.7
Nishino, H.8
Tanaka, T.9
-
64
-
-
72149105299
-
Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KSJ-DB/DB mice
-
Miyamoto, S.; Yasui, Y.; Ohigashi, H.; Tanaka, T.; Murakami, A. Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KSJ-DB/DB mice. Chem. Biol. Interact. 2010, 183, 276–283.
-
(2010)
Chem. Biol. Interact
, vol.183
, pp. 276-283
-
-
Miyamoto, S.1
Yasui, Y.2
Ohigashi, H.3
Tanaka, T.4
Murakami, A.5
-
65
-
-
47249110701
-
Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice
-
Miyamoto, S.; Yasui, Y.; Tanaka, T.; Ohigashi, H.; Murakami, A. Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice. Carcinogenesis 2008, 29, 1057–1063.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1057-1063
-
-
Miyamoto, S.1
Yasui, Y.2
Tanaka, T.3
Ohigashi, H.4
Murakami, A.5
-
66
-
-
56149116774
-
Apoptotic effect of Citrus fruit extract nobiletin on lung cancer cell line a549 in vitro and in vivo
-
Luo, G.; Guan, X.; Zhou, L. Apoptotic effect of Citrus fruit extract nobiletin on lung cancer cell line a549 in vitro and in vivo. Cancer Biol. Ther. 2008, 7, 966–973.
-
(2008)
Cancer Biol. Ther
, vol.7
, pp. 966-973
-
-
Luo, G.1
Guan, X.2
Zhou, L.3
-
67
-
-
19944427056
-
Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo
-
Ohnishi, H.; Asamoto, M.; Tujimura, K.; Hokaiwado, N.; Takahashi, S.; Ogawa, K.; Kuribayashi, M.; Ogiso, T.; Okuyama, H.; Shirai, T. Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo. Cancer Sci. 2004, 95, 936–942.
-
(2004)
Cancer Sci
, vol.95
, pp. 936-942
-
-
Ohnishi, H.1
Asamoto, M.2
Tujimura, K.3
Hokaiwado, N.4
Takahashi, S.5
Ogawa, K.6
Kuribayashi, M.7
Ogiso, T.8
Okuyama, H.9
Shirai, T.10
-
68
-
-
84876950012
-
Nobiletin induces inhibitions of RAS activity and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells
-
Aoki, K.; Yokosuka, A.; Mimaki, Y.; Fukunaga, K.; Yamakuni, T. Nobiletin induces inhibitions of RAS activity and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells. Biol. Pharm. Bull. 2013, 36, 540–547.
-
(2013)
Biol. Pharm. Bull
, vol.36
, pp. 540-547
-
-
Aoki, K.1
Yokosuka, A.2
Mimaki, Y.3
Fukunaga, K.4
Yamakuni, T.5
-
69
-
-
84956958860
-
Nobiletin, a polymethoxylated flavone, inhibits glioma cell growth and migration via arresting cell cycle and suppressing MAPK and Akt pathways
-
Lien, L.M.; Wang, M.J.; Chen, R.J.; Chiu, H.C.; Wu, J.L.; Shen, M.Y.; Chou, D.S.; Sheu, J.R.; Lin, K.H.; Lu, W.J. Nobiletin, a polymethoxylated flavone, inhibits glioma cell growth and migration via arresting cell cycle and suppressing MAPK and Akt pathways. Phytother. Res. 2016, 30, 214–221.
-
(2016)
Phytother. Res
, vol.30
, pp. 214-221
-
-
Lien, L.M.1
Wang, M.J.2
Chen, R.J.3
Chiu, H.C.4
Wu, J.L.5
Shen, M.Y.6
Chou, D.S.7
Sheu, J.R.8
Lin, K.H.9
Lu, W.J.10
-
70
-
-
84874622060
-
Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells
-
Moon, J.Y.; Cho, M.; Ahn, K.S.; Cho, S.K. Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells. Nutr. Cancer Int. J. 2013, 65, 286–295.
-
(2013)
Nutr. Cancer Int. J
, vol.65
, pp. 286-295
-
-
Moon, J.Y.1
Cho, M.2
Ahn, K.S.3
Cho, S.K.4
-
71
-
-
84925286068
-
Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells
-
Hsiao, P.C.; Lee, W.J.; Yang, S.F.; Tan, P.; Chen, H.Y.; Lee, L.M.; Chang, J.L.; Lai, G.M.; Chow, J.M.; Chien, M.H. Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells. Tumor Biol. 2014, 35, 11903–11911.
-
(2014)
Tumor Biol
, vol.35
, pp. 11903-11911
-
-
Hsiao, P.C.1
Lee, W.J.2
Yang, S.F.3
Tan, P.4
Chen, H.Y.5
Lee, L.M.6
Chang, J.L.7
Lai, G.M.8
Chow, J.M.9
Chien, M.H.10
-
72
-
-
84952769409
-
Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis
-
Wu, X.; Song, M.Y.; Wang, M.Q.; Zheng, J.K.; Gao, Z.L.; Xu, F.; Zhang, G.D.; Xiao, H. Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis. Mol. Nutr. Food Res. 2015, 59, 2383–2394.
-
(2015)
Mol. Nutr. Food Res
, vol.59
, pp. 2383-2394
-
-
Wu, X.1
Song, M.Y.2
Wang, M.Q.3
Zheng, J.K.4
Gao, Z.L.5
Xu, F.6
Zhang, G.D.7
Xiao, H.8
-
73
-
-
68549088745
-
Apigenin induces apoptosis through a mitochondria/caspase-pathway in human breast cancer MDA-MB-453 cells
-
Choi, E.J.; Kim, G.H. Apigenin induces apoptosis through a mitochondria/caspase-pathway in human breast cancer MDA-MB-453 cells. J. Clin. Biochem. Nutr. 2009, 44, 260–265.
-
(2009)
J. Clin. Biochem. Nutr
, vol.44
, pp. 260-265
-
-
Choi, E.J.1
Kim, G.H.2
-
74
-
-
84862016307
-
Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells
-
Seo, H.S.; Choi, H.S.; Kim, S.R.; Choi, Y.K.; Woo, S.M.; Shin, I.; Woo, J.K.; Park, S.Y.; Shin, Y.C.; Ko, S.K. Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells. Mol. Cell. Biochem. 2012, 366, 319–334.
-
(2012)
Mol. Cell. Biochem
, vol.366
, pp. 319-334
-
-
Seo, H.S.1
Choi, H.S.2
Kim, S.R.3
Choi, Y.K.4
Woo, S.M.5
Shin, I.6
Woo, J.K.7
Park, S.Y.8
Shin, Y.C.9
Ko, S.K.10
-
75
-
-
1042289764
-
Apigenin induces apoptosis through proteasomal degradation of HER2/NEU in HER2/NEU-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway
-
Way, T.D.; Kao, M.C.; Lin, J.K. Apigenin induces apoptosis through proteasomal degradation of HER2/NEU in HER2/NEU-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 2004, 279, 4479–4489.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 4479-4489
-
-
Way, T.D.1
Kao, M.C.2
Lin, J.K.3
-
76
-
-
33750848203
-
Regulation of the p14ARF-MDM2-p53 pathway: An overview in breast cancer
-
Agrawal, A.; Yang, J.; Murphy, R.F.; Agrawal, D.K. Regulation of the p14ARF-MDM2-p53 pathway: An overview in breast cancer. Exp. Mol. Pathol. 2006, 81, 115–122.
-
(2006)
Exp. Mol. Pathol
, vol.81
, pp. 115-122
-
-
Agrawal, A.1
Yang, J.2
Murphy, R.F.3
Agrawal, D.K.4
-
77
-
-
21644463156
-
Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway
-
Takagaki, N.; Sowa, Y.; Oki, T.; Nakanishi, R.; Yogosawa, S.; Sakai, T. Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway. Int. J. Oncol. 2005, 26, 185–189.
-
(2005)
Int. J. Oncol
, vol.26
, pp. 185-189
-
-
Takagaki, N.1
Sowa, Y.2
Oki, T.3
Nakanishi, R.4
Yogosawa, S.5
Sakai, T.6
-
78
-
-
0030796989
-
Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin
-
Lepley, D.M.; Pelling, J.C. Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin. Mol. Carcinog. 1997, 19, 74–82.
-
(1997)
Mol. Carcinog
, vol.19
, pp. 74-82
-
-
Lepley, D.M.1
Pelling, J.C.2
-
79
-
-
0029912852
-
Flavonoids activate wild-type p53
-
Plaumann, B.; Fritsche, M.; Rimpler, H.; Brandner, G.; Hess, R.D. Flavonoids activate wild-type p53. Oncogene 1996, 13, 1605–1614.
-
(1996)
Oncogene
, vol.13
, pp. 1605-1614
-
-
Plaumann, B.1
Fritsche, M.2
Rimpler, H.3
Brandner, G.4
Hess, R.D.5
-
80
-
-
0035059767
-
Apigenin inhibits growth and induces G2/M arrest by modulating cyclin-CDK regulators and ERK MAP Kinase activation in breast carcinoma cells
-
Yin, F.; Giuliano, A.E.; Law, R.E.; Van Herle, A.J. Apigenin inhibits growth and induces G2/M arrest by modulating cyclin-CDK regulators and ERK MAP Kinase activation in breast carcinoma cells. Anticancer Res. 2001, 21, 413–420.
-
(2001)
Anticancer Res
, vol.21
, pp. 413-420
-
-
Yin, F.1
Giuliano, A.E.2
Law, R.E.3
Van Herle, A.J.4
-
81
-
-
84862779346
-
Evidence for activation of mutated p53 by apigenin in human pancreatic cancer
-
King, J.C.; Lu, Q.Y.; Li, G.; Moro, A.; Takahashi, H.; Chen, M.; Go, V.L.; Reber, H.A.; Eibl, G.; Hines, O.J. Evidence for activation of mutated p53 by apigenin in human pancreatic cancer. Biochim. Biophys. Acta 2012, 1823, 593–604.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 593-604
-
-
King, J.C.1
Lu, Q.Y.2
Li, G.3
Moro, A.4
Takahashi, H.5
Chen, M.6
Go, V.L.7
Reber, H.A.8
Eibl, G.9
Hines, O.J.10
-
82
-
-
33846653627
-
Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
-
[CrossRef]
-
Ujiki, M.B.; Ding, X.Z.; Salabat, M.R.; Bentrem, D.J.; Golkar, L.; Milam, B.; Talamonti, M.S.; Bell, R.H., Jr.; Iwamura, T.; Adrian, T.E. Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. Mol. Cancer 2006, 5, 76. [CrossRef]
-
(2006)
Mol. Cancer
, vol.5
, pp. 76
-
-
Ujiki, M.B.1
Ding, X.Z.2
Salabat, M.R.3
Bentrem, D.J.4
Golkar, L.5
Milam, B.6
Talamonti, M.S.7
Bell, R.H.8
Iwamura, T.9
Adrian, T.E.10
-
83
-
-
84881495790
-
Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3 beta/NFκB signaling cascade
-
Johnson, J.L.; de Mejia, E.G. Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3 beta/NFκB signaling cascade. Mol. Nutr. Food Res. 2013, 57, 2112–2127.
-
(2013)
Mol. Nutr. Food Res
, vol.57
, pp. 2112-2127
-
-
Johnson, J.L.1
De Mejia, E.G.2
-
84
-
-
0037161915
-
Involvement of nuclear factor-kappa B, BAX and BCL-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells
-
Gupta, S.; Afaq, F.; Mukhtar, H. Involvement of nuclear factor-kappa B, BAX and BCL-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene 2002, 21, 3727–3738.
-
(2002)
Oncogene
, vol.21
, pp. 3727-3738
-
-
Gupta, S.1
Afaq, F.2
Mukhtar, H.3
-
85
-
-
0842325655
-
Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells
-
Shukla, S.; Gupta, S. Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells. Mol. Carcinog. 2004, 39, 114–126.
-
(2004)
Mol. Carcinog
, vol.39
, pp. 114-126
-
-
Shukla, S.1
Gupta, S.2
-
86
-
-
0033933197
-
Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines
-
Wang, W.; Heideman, L.; Chung, C.S.; Pelling, J.C.; Koehler, K.J.; Birt, D.F. Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol. Carcinog. 2000, 28, 102–110.
-
(2000)
Mol. Carcinog
, vol.28
, pp. 102-110
-
-
Wang, W.1
Heideman, L.2
Chung, C.S.3
Pelling, J.C.4
Koehler, K.J.5
Birt, D.F.6
-
87
-
-
78649635941
-
Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53
-
Zhong, Y.; Krisanapun, C.; Lee, S.H.; Nualsanit, T.; Sams, C.; Peungvicha, P.; Baek, S.J. Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53. Eur. J. Cancer 2010, 46, 3365–3374.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 3365-3374
-
-
Zhong, Y.1
Krisanapun, C.2
Lee, S.H.3
Nualsanit, T.4
Sams, C.5
Peungvicha, P.6
Baek, S.J.7
-
88
-
-
33646583485
-
Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft
-
Shukla, S.; Gupta, S. Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft. Mol. Cancer Ther. 2006, 5, 843–852.
-
(2006)
Mol. Cancer Ther
, vol.5
, pp. 843-852
-
-
Shukla, S.1
Gupta, S.2
-
89
-
-
33750612111
-
Mechanism of apoptosis with the involvement of calpain and caspase cascades in human malignant neuroblastoma SH-SY5Y cells exposed to flavonoids
-
Das, A.; Banik, N.L.; Ray, S.K. Mechanism of apoptosis with the involvement of calpain and caspase cascades in human malignant neuroblastoma SH-SY5Y cells exposed to flavonoids. Int. J. Cancer 2006, 119, 2575–2585.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 2575-2585
-
-
Das, A.1
Banik, N.L.2
Ray, S.K.3
-
90
-
-
13944251086
-
Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma
-
Torkin, R.; Lavoie, J.F.; Kaplan, D.R.; Yeger, H. Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma. Mol. Cancer Ther. 2005, 4, 1–11.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 1-11
-
-
Torkin, R.1
Lavoie, J.F.2
Kaplan, D.R.3
Yeger, H.4
-
91
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646–674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
92
-
-
0032815147
-
Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
-
Kuntz, S.; Wenzel, U.; Daniel, H. Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur. J. Nutr. 1999, 38, 133–142.
-
(1999)
Eur. J. Nutr
, vol.38
, pp. 133-142
-
-
Kuntz, S.1
Wenzel, U.2
Daniel, H.3
-
93
-
-
84859364854
-
PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression
-
Dung, T.D.; Day, C.H.; Binh, T.V.; Lin, C.H.; Hsu, H.H.; Su, C.C.; Lin, Y.M.; Tsai, F.J.; Kuo, W.W.; Chen, L.M.; et al. PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression. Food Chem. Toxicol. 2012, 50, 1802–1810.
-
(2012)
Food Chem. Toxicol
, vol.50
, pp. 1802-1810
-
-
Dung, T.D.1
Day, C.H.2
Binh, T.V.3
Lin, C.H.4
Hsu, H.H.5
Su, C.C.6
Lin, Y.M.7
Tsai, F.J.8
Kuo, W.W.9
Chen, L.M.10
-
94
-
-
84920379833
-
Diosmin induces genotoxicity and apoptosis in DU145 prostate cancer cell line
-
Lewinska, A.; Siwak, J.; Rzeszutek, I.; Wnuk, M. Diosmin induces genotoxicity and apoptosis in DU145 prostate cancer cell line. Toxicol. Vitr. 2015, 29, 417–425.
-
(2015)
Toxicol. Vitr
, vol.29
, pp. 417-425
-
-
Lewinska, A.1
Siwak, J.2
Rzeszutek, I.3
Wnuk, M.4
-
95
-
-
6844250963
-
Modulation of N-methyl-N-amylnitrosamine-induced rat oesophageal tumourigenesis by dietary feeding of diosmin and hesperidin, both alone and in combination
-
Tanaka, T.; Makita, H.; Kawabata, K.; Mori, H.; Kakumoto, M.; Satoh, K.; Hara, A.; Sumida, T.; Fukutani, K.; Tanaka, T.; et al. Modulation of N-methyl-N-amylnitrosamine-induced rat oesophageal tumourigenesis by dietary feeding of diosmin and hesperidin, both alone and in combination. Carcinogenesis 1997, 18, 761–769.
-
(1997)
Carcinogenesis
, vol.18
, pp. 761-769
-
-
Tanaka, T.1
Makita, H.2
Kawabata, K.3
Mori, H.4
Kakumoto, M.5
Satoh, K.6
Hara, A.7
Sumida, T.8
Fukutani, K.9
Tanaka, T.10
-
96
-
-
14444275051
-
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination
-
Tanaka, T.; Makita, H.; Ohnishi, M.; Mori, H.; Satoh, K.; Hara, A.; Sumida, T.; Fukutani, K.; Tanaka, T.; Ogawa, H. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination. Cancer Res. 1997, 57, 246–252.
-
(1997)
Cancer Res
, vol.57
, pp. 246-252
-
-
Tanaka, T.1
Makita, H.2
Ohnishi, M.3
Mori, H.4
Satoh, K.5
Hara, A.6
Sumida, T.7
Fukutani, K.8
Tanaka, T.9
Ogawa, H.10
-
97
-
-
0031588366
-
Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice
-
Yang, M.; Tanaka, T.; Hirose, Y.; Deguchi, T.; Mori, H.; Kawada, Y. Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice. Int. J. Cancer 1997, 73, 719–724.
-
(1997)
Int. J. Cancer
, vol.73
, pp. 719-724
-
-
Yang, M.1
Tanaka, T.2
Hirose, Y.3
Deguchi, T.4
Mori, H.5
Kawada, Y.6
-
98
-
-
0031417008
-
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin
-
Tanaka, T.; Makita, H.; Kawabata, K.; Mori, H.; Kakumoto, M.; Satoh, K.; Hara, A.; Sumida, T.; Tanaka, T.; Ogawa, H. Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin. Carcinogenesis 1997, 18, 957–965.
-
(1997)
Carcinogenesis
, vol.18
, pp. 957-965
-
-
Tanaka, T.1
Makita, H.2
Kawabata, K.3
Mori, H.4
Kakumoto, M.5
Satoh, K.6
Hara, A.7
Sumida, T.8
Tanaka, T.9
Ogawa, H.10
-
99
-
-
33748704067
-
Phenylbenzopyrones structure-activity studies identify betuletol derivatives as potential antitumoral agents
-
Rubio, S.; Quintana, J.; Lopez, M.; Eiroa, J.L.; Triana, J.; Estevez, F. Phenylbenzopyrones structure-activity studies identify betuletol derivatives as potential antitumoral agents. Eur. J. Pharmacol. 2006, 548, 9–20.
-
(2006)
Eur. J. Pharmacol
, vol.548
, pp. 9-20
-
-
Rubio, S.1
Quintana, J.2
Lopez, M.3
Eiroa, J.L.4
Triana, J.5
Estevez, F.6
-
100
-
-
23044500473
-
Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants
-
Duraj, J.; Zazrivcova, K.; Bodo, J.; Sulikova, M.; Sedlak, J. Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants. Neoplasma 2005, 52, 273–279.
-
(2005)
Neoplasma
, vol.52
, pp. 273-279
-
-
Duraj, J.1
Zazrivcova, K.2
Bodo, J.3
Sulikova, M.4
Sedlak, J.5
-
101
-
-
0027463393
-
Type II estrogen binding sites and antiproliferative activity of quercetin in human meningiomas
-
Piantelli, M.; Rinelli, A.; Macri, E.; Maggiano, N.; Larocca, L.M.; Scerrati, M.; Roselli, R.; Iacoangeli, M.; Scambia, G.; Capelli, A.; et al. Type II estrogen binding sites and antiproliferative activity of quercetin in human meningiomas. Cancer 1993, 71, 193–198.
-
(1993)
Cancer
, vol.71
, pp. 193-198
-
-
Piantelli, M.1
Rinelli, A.2
Macri, E.3
Maggiano, N.4
Larocca, L.M.5
Scerrati, M.6
Roselli, R.7
Iacoangeli, M.8
Scambia, G.9
Capelli, A.10
-
102
-
-
0030596107
-
Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells
-
Kuo, S.M. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett. 1996, 110, 41–48.
-
(1996)
Cancer Lett
, vol.110
, pp. 41-48
-
-
Kuo, S.M.1
-
103
-
-
79952641157
-
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines
-
Araujo, J.R.; Goncalves, P.; Martel, F. Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nutr. Res. 2011, 31, 77–87.
-
(2011)
Nutr. Res
, vol.31
, pp. 77-87
-
-
Araujo, J.R.1
Goncalves, P.2
Martel, F.3
-
104
-
-
15244352791
-
Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound
-
Paliwal, S.; Sundaram, J.; Mitragotri, S. Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound. Br. J. Cancer 2005, 92, 499–502.
-
(2005)
Br. J. Cancer
, vol.92
, pp. 499-502
-
-
Paliwal, S.1
Sundaram, J.2
Mitragotri, S.3
-
105
-
-
79959262105
-
1,2,3,4,6-penta-O-galloyl-beta-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of SKP2 protein
-
Huang, H.C.; Lin, C.L.; Lin, J.K. 1,2,3,4,6-penta-O-galloyl-beta-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of SKP2 protein. J. Agric. Food Chem. 2011, 59, 6765–6775.
-
(2011)
J. Agric. Food Chem
, vol.59
, pp. 6765-6775
-
-
Huang, H.C.1
Lin, C.L.2
Lin, J.K.3
-
106
-
-
84872612639
-
Quercetin-3-methyl ether inhibits lapatinib-sensitive and -resistant breast cancer cell growth by inducing G(2)/M arrest and apoptosis. Mol
-
Li, J.; Zhu, F.; Lubet, R.A.; De Luca, A.; Grubbs, C.; Ericson, M.E.; D’Alessio, A.; Normanno, N.; Dong, Z.; Bode, A.M. Quercetin-3-methyl ether inhibits lapatinib-sensitive and -resistant breast cancer cell growth by inducing G(2)/M arrest and apoptosis. Mol. Carcinog. 2011, 52, 134–143.
-
(2011)
Carcinog
, vol.52
, pp. 134-143
-
-
Li, J.1
Zhu, F.2
Lubet, R.A.3
De Luca, A.4
Grubbs, C.5
Ericson, M.E.6
D’Alessio, A.7
Normanno, N.8
Dong, Z.9
Bode, A.M.10
-
107
-
-
82455192269
-
Drug combinations with quercetin: Doxorubicin plus quercetin in human breast cancer cells. Cancer Chemother
-
Staedler, D.; Idrizi, E.; Kenzaoui, B.H.; Juillerat-Jeanneret, L. Drug combinations with quercetin: Doxorubicin plus quercetin in human breast cancer cells. Cancer Chemother. Pharmacol. 2011, 68, 1161–1172.
-
(2011)
Pharmacol
, vol.68
, pp. 1161-1172
-
-
Staedler, D.1
Idrizi, E.2
Kenzaoui, B.H.3
Juillerat-Jeanneret, L.4
-
108
-
-
0027981909
-
Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother
-
Scambia, G.; Ranelletti, F.O.; Panici, P.B.; De Vincenzo, R.; Bonanno, G.; Ferrandina, G.; Piantelli, M.; Bussa, S.; Rumi, C.; Cianfriglia, M.; et al. Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother. Pharmacol. 1994, 34, 459–464.
-
(1994)
Pharmacol
, vol.34
, pp. 459-464
-
-
Scambia, G.1
Ranelletti, F.O.2
Panici, P.B.3
De Vincenzo, R.4
Bonanno, G.5
Ferrandina, G.6
Piantelli, M.7
Bussa, S.8
Rumi, C.9
Cianfriglia, M.10
-
109
-
-
0028172728
-
Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of p-glycoprotein as a putative mechanism
-
Critchfield, J.W.; Welsh, C.J.; Phang, J.M.; Yeh, G.C. Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of p-glycoprotein as a putative mechanism. Biochem. Pharmacol. 1994, 48, 1437–1445.
-
(1994)
Biochem. Pharmacol
, vol.48
, pp. 1437-1445
-
-
Critchfield, J.W.1
Welsh, C.J.2
Phang, J.M.3
Yeh, G.C.4
-
110
-
-
21144450349
-
Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice
-
Kanno, S.; Tomizawa, A.; Hiura, T.; Osanai, Y.; Shouji, A.; Ujibe, M.; Ohtake, T.; Kimura, K.; Ishikawa, M. Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice. Biol. Pharm. Bull. 2005, 28, 527–530.
-
(2005)
Biol. Pharm. Bull
, vol.28
, pp. 527-530
-
-
Kanno, S.1
Tomizawa, A.2
Hiura, T.3
Osanai, Y.4
Shouji, A.5
Ujibe, M.6
Ohtake, T.7
Kimura, K.8
Ishikawa, M.9
-
111
-
-
33747881688
-
Naringenin-induced apoptosis via activation of NF-κB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells
-
Kanno, S.; Tomizawa, A.; Ohtake, T.; Koiwai, K.; Ujibe, M.; Ishikawa, M. Naringenin-induced apoptosis via activation of NF-κB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicol. Lett. 2006, 166, 131–139.
-
(2006)
Toxicol. Lett
, vol.166
, pp. 131-139
-
-
Kanno, S.1
Tomizawa, A.2
Ohtake, T.3
Koiwai, K.4
Ujibe, M.5
Ishikawa, M.6
-
112
-
-
0037359775
-
The variable effect on proliferation of a colon cancer cell line by the Citrus fruit flavonoid naringenin
-
Frydoonfar, H.R.; McGrath, D.R.; Spigelman, A.D. The variable effect on proliferation of a colon cancer cell line by the Citrus fruit flavonoid naringenin. Colorectal Dis. 2003, 5, 149–152.
-
(2003)
Colorectal Dis
, vol.5
, pp. 149-152
-
-
Frydoonfar, H.R.1
McGrath, D.R.2
Spigelman, A.D.3
-
113
-
-
3342944401
-
Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: A mechanism for impaired cellular proliferation
-
Harmon, A.W.; Patel, Y.M. Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: A mechanism for impaired cellular proliferation. Breast Cancer Res. Treat. 2004, 85, 103–110.
-
(2004)
Breast Cancer Res. Treat
, vol.85
, pp. 103-110
-
-
Harmon, A.W.1
Patel, Y.M.2
-
114
-
-
55949118960
-
Naringenin induces apoptosis through downregulation of AKT and caspase-3 activation in human leukemia THP-1 cells
-
Park, J.H.; Jin, C.Y.; Lee, B.K.; Kim, G.Y.; Choi, Y.H.; Jeong, Y.K. Naringenin induces apoptosis through downregulation of AKT and caspase-3 activation in human leukemia THP-1 cells. Food Chem. Toxicol. 2008, 46, 3684–3690.
-
(2008)
Food Chem. Toxicol
, vol.46
, pp. 3684-3690
-
-
Park, J.H.1
Jin, C.Y.2
Lee, B.K.3
Kim, G.Y.4
Choi, Y.H.5
Jeong, Y.K.6
-
115
-
-
84946781848
-
Co-treatment of THP-1 cells with naringenin and curcumin induces cell cycle arrest and apoptosis via numerous pathways
-
Shi, D.; Xu, Y.; Du, X.; Chen, X.; Zhang, X.; Lou, J.; Li, M.; Zhuo, J. Co-treatment of THP-1 cells with naringenin and curcumin induces cell cycle arrest and apoptosis via numerous pathways. Mol. Med. Rep. 2015, 12, 8223–8228.
-
(2015)
Mol. Med. Rep
, vol.12
, pp. 8223-8228
-
-
Shi, D.1
Xu, Y.2
Du, X.3
Chen, X.4
Zhang, X.5
Lou, J.6
Li, M.7
Zhuo, J.8
-
116
-
-
84908054200
-
Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest
-
Ahamad, M.S.; Siddiqui, S.; Jafri, A.; Ahmad, S.; Afzal, M.; Arshad, M. Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest. PLoS ONE 2014, 9, e110003.
-
(2014)
PLoS ONE
, vol.9
-
-
Ahamad, M.S.1
Siddiqui, S.2
Jafri, A.3
Ahmad, S.4
Afzal, M.5
Arshad, M.6
-
117
-
-
77953663204
-
Simultaneous quantitative monitoring of drug-induced caspase cascade pathways in carcinoma cells
-
Naoghare, P.K.; Ki, H.A.; Paek, S.M.; Tak, Y.K.; Suh, Y.G.; Kim, S.G.; Leeb, K.H.; Song, J.M. Simultaneous quantitative monitoring of drug-induced caspase cascade pathways in carcinoma cells. Integr. Biol. 2010, 2, 46–57.
-
(2010)
Integr. Biol
, vol.2
, pp. 46-57
-
-
Naoghare, P.K.1
Ki, H.A.2
Paek, S.M.3
Tak, Y.K.4
Suh, Y.G.5
Kim, S.G.6
Leeb, K.H.7
Song, J.M.8
-
118
-
-
79551514638
-
Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells
-
Jin, C.Y.; Park, C.; Hwang, H.J.; Kim, G.Y.; Choi, B.T.; Kim, W.J.; Choi, Y.H. Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells. Mol. Nutr. Food Res. 2011, 55, 300–309.
-
(2011)
Mol. Nutr. Food Res
, vol.55
, pp. 300-309
-
-
Jin, C.Y.1
Park, C.2
Hwang, H.J.3
Kim, G.Y.4
Choi, B.T.5
Kim, W.J.6
Choi, Y.H.7
-
119
-
-
2142711101
-
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
-
Zhang, S.Z.; Yang, X.N.; Morris, M.E. Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol. Pharmacol. 2004, 65, 1208–1216.
-
(2004)
Mol. Pharmacol
, vol.65
, pp. 1208-1216
-
-
Zhang, S.Z.1
Yang, X.N.2
Morris, M.E.3
-
120
-
-
22144481699
-
Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein
-
Zhang, S.Z.; Yang, X.N.; Coburn, R.A.; Morris, M.E. Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein. Biochem. Pharmacol. 2005, 70, 627–639.
-
(2005)
Biochem. Pharmacol
, vol.70
, pp. 627-639
-
-
Zhang, S.Z.1
Yang, X.N.2
Coburn, R.A.3
Morris, M.E.4
-
121
-
-
7544245330
-
Effects of grapefruit juice on the multidrug transporter p-glycoprotein in the human proximal tubular cell line HK-2
-
Romiti, N.; Tramonti, G.; Donati, A.; Chieli, E. Effects of grapefruit juice on the multidrug transporter p-glycoprotein in the human proximal tubular cell line HK-2. Life Sci. 2004, 76, 293–302.
-
(2004)
Life Sci
, vol.76
, pp. 293-302
-
-
Romiti, N.1
Tramonti, G.2
Donati, A.3
Chieli, E.4
-
122
-
-
0035196221
-
Effect of p-glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis
-
Tsai, T.H.; Lee, C.H.; Yeh, P.H. Effect of p-glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis. Br. J. Pharmacol. 2001, 134, 1245–1252.
-
(2001)
Br. J. Pharmacol
, vol.134
, pp. 1245-1252
-
-
Tsai, T.H.1
Lee, C.H.2
Yeh, P.H.3
-
123
-
-
47349108866
-
Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats
-
De Castro, W.V.; Mertens-Talcott, S.; Derendorf, H.; Butterweck, V. Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats. J. Agric. Food Chem. 2008, 56, 4840–4845.
-
(2008)
J. Agric. Food Chem
, vol.56
, pp. 4840-4845
-
-
De Castro, W.V.1
Mertens-Talcott, S.2
Derendorf, H.3
Butterweck, V.4
-
124
-
-
61449258247
-
Naringenin enhances the anti-tumor effect of doxorubicin through selectively inhibiting the activity of multidrug resistance-associated proteins but not p-glycoprotein
-
Zhang, F.Y.; Du, G.J.; Zhang, L.; Zhang, C.L.; Lu, W.L.; Liang, W. Naringenin enhances the anti-tumor effect of doxorubicin through selectively inhibiting the activity of multidrug resistance-associated proteins but not p-glycoprotein. Pharm. Res. 2009, 26, 914–925.
-
(2009)
Pharm. Res
, vol.26
, pp. 914-925
-
-
Zhang, F.Y.1
Du, G.J.2
Zhang, L.3
Zhang, C.L.4
Lu, W.L.5
Liang, W.6
-
125
-
-
79959921537
-
Minor effects of the citrus flavonoids naringin, naringenin and quercetin, on the pharmacokinetics of doxorubicin in rats
-
Park, H.S.; Oh, J.H.; Lee, J.H.; Lee, Y.J. Minor effects of the citrus flavonoids naringin, naringenin and quercetin, on the pharmacokinetics of doxorubicin in rats. Pharmazie 2011, 66, 424–429.
-
(2011)
Pharmazie
, vol.66
, pp. 424-429
-
-
Park, H.S.1
Oh, J.H.2
Lee, J.H.3
Lee, Y.J.4
-
126
-
-
38349087272
-
Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats
-
Ekambaram, G.; Rajendran, P.; Magesh, V.; Sakthisekaran, D. Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats. Nutr. Res. 2008, 28, 106–112.
-
(2008)
Nutr. Res
, vol.28
, pp. 106-112
-
-
Ekambaram, G.1
Rajendran, P.2
Magesh, V.3
Sakthisekaran, D.4
-
127
-
-
50649083268
-
Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine-and saturated sodium chloride-induced gastric carcinogenesis in male wistar rats
-
Ganapathy, E.; Peramaiyan, R.; Rajasekaran, D.; Venkataraman, M.; Dhanapal, S. Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine-and saturated sodium chloride-induced gastric carcinogenesis in male wistar rats. Clin. Exp. Pharmacol. Physiol. 2008, 35, 1190–1196.
-
(2008)
Clin. Exp. Pharmacol. Physiol
, vol.35
, pp. 1190-1196
-
-
Ganapathy, E.1
Peramaiyan, R.2
Rajasekaran, D.3
Venkataraman, M.4
Dhanapal, S.5
-
128
-
-
78449310221
-
Naringenin promote apoptosis in cerebrally implanted C6 glioma cells
-
Sabarinathan, D.; Mahalakshmi, P.; Vanisree, A.J. Naringenin promote apoptosis in cerebrally implanted C6 glioma cells. Mol. Cell. Biochem. 2010, 345, 215–222.
-
(2010)
Mol. Cell. Biochem
, vol.345
, pp. 215-222
-
-
Sabarinathan, D.1
Mahalakshmi, P.2
Vanisree, A.J.3
-
129
-
-
38749126787
-
Inhibition of oral carcinogenesis by Citrus flavonoids
-
Miller, E.G.; Peacock, J.J.; Bourland, T.C.; Taylor, S.E.; Wright, J.A.; Patil, B.S.; Miller, E.G. Inhibition of oral carcinogenesis by Citrus flavonoids. Nutr. Cancer Int. J. 2008, 60, 69–74.
-
(2008)
Nutr. Cancer Int. J
, vol.60
, pp. 69-74
-
-
Miller, E.G.1
Peacock, J.J.2
Bourland, T.C.3
Taylor, S.E.4
Wright, J.A.5
Patil, B.S.6
Miller, E.G.7
-
130
-
-
84867236923
-
Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells
-
Ramesh, E.; Alshatwi, A.A. Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells. Food Chem. Toxicol. 2013, 51, 97–105.
-
(2013)
Food Chem. Toxicol
, vol.51
, pp. 97-105
-
-
Ramesh, E.1
Alshatwi, A.A.2
-
131
-
-
84907202598
-
Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NFκB/COX2caspase-1 pathway in HeLa cervical cancer cells
-
Zeng, L.; Zhen, Y.; Chen, Y.; Zou, L.; Zhang, Y.; Hu, F.; Feng, J.; Shen, J.; Wei, B. Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NFκB/COX2caspase-1 pathway in HeLa cervical cancer cells. Int. J. Oncol. 2014, 45, 1929–1936.
-
(2014)
Int. J. Oncol
, vol.45
, pp. 1929-1936
-
-
Zeng, L.1
Zhen, Y.2
Chen, Y.3
Zou, L.4
Zhang, Y.5
Hu, F.6
Feng, J.7
Shen, J.8
Wei, B.9
-
132
-
-
84964797289
-
Neu3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation
-
Yoshinaga, A.; Kajiya, N.; Oishi, K.; Kamada, Y.; Ikeda, A.; Chigwechokha, P.K.; Kibe, T.; Kishida, M.; Kishida, S.; Komatsu, M.; et al. Neu3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation. Eur. J. Pharmacol. 2016, 782, 21–29.
-
(2016)
Eur. J. Pharmacol
, vol.782
, pp. 21-29
-
-
Yoshinaga, A.1
Kajiya, N.2
Oishi, K.3
Kamada, Y.4
Ikeda, A.5
Chigwechokha, P.K.6
Kibe, T.7
Kishida, M.8
Kishida, S.9
Komatsu, M.10
-
133
-
-
84879519304
-
Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting beta-catenin signaling pathway
-
Li, H.; Yang, B.; Huang, J.; Xiang, T.; Yin, X.; Wan, J.; Luo, F.; Zhang, L.; Li, H.; Ren, G. Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting beta-catenin signaling pathway. Toxicol. Lett. 2013, 220, 219–228.
-
(2013)
Toxicol. Lett
, vol.220
, pp. 219-228
-
-
Li, H.1
Yang, B.2
Huang, J.3
Xiang, T.4
Yin, X.5
Wan, J.6
Luo, F.7
Zhang, L.8
Li, H.9
Ren, G.10
-
134
-
-
51849143663
-
Requirement for RAS/RAF/ERK pathway in naringin-induced G(1)-cell-cycle arrest via p21WAF1 expression
-
Kim, D.I.; Lee, S.J.; Lee, S.B.; Park, K.; Kim, W.J.; Moon, S.K. Requirement for RAS/RAF/ERK pathway in naringin-induced G(1)-cell-cycle arrest via p21WAF1 expression. Carcinogenesis 2008, 29, 1701–1709.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1701-1709
-
-
Kim, D.I.1
Lee, S.J.2
Lee, S.B.3
Park, K.4
Kim, W.J.5
Moon, S.K.6
-
135
-
-
80052267544
-
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation
-
Xie, C.M.; Chan, W.Y.; Yu, S.; Zhao, J.; Cheng, C.H. Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation. Free Radic. Biol. Med. 2011, 51, 1365–1375.
-
(2011)
Free Radic. Biol. Med
, vol.51
, pp. 1365-1375
-
-
Xie, C.M.1
Chan, W.Y.2
Yu, S.3
Zhao, J.4
Cheng, C.H.5
-
136
-
-
84905019107
-
Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma
-
Chen, Y.J.; Chi, C.W.; Su, W.C.; Huang, H.L. Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma. Oncotarget 2014, 5, 4845–4854.
-
(2014)
Oncotarget
, vol.5
, pp. 4845-4854
-
-
Chen, Y.J.1
Chi, C.W.2
Su, W.C.3
Huang, H.L.4
-
137
-
-
84938097560
-
Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/AKT/MTOR cascade via activation of MAPK pathways in AGS cancer cells
-
Raha, S.; Yumnam, S.; Hong, G.E.; Lee, H.J.; Saralamma, V.V.; Park, H.S.; Heo, J.D.; Lee, S.J.; Kim, E.H.; Kim, J.A.; et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/AKT/MTOR cascade via activation of MAPK pathways in AGS cancer cells. Int. J. Oncol. 2015, 47, 1061–1069.
-
(2015)
Int. J. Oncol
, vol.47
, pp. 1061-1069
-
-
Raha, S.1
Yumnam, S.2
Hong, G.E.3
Lee, H.J.4
Saralamma, V.V.5
Park, H.S.6
Heo, J.D.7
Lee, S.J.8
Kim, E.H.9
Kim, J.A.10
-
138
-
-
85011887996
-
Naringin suppresses the development of glioblastoma by inhibiting FAK activity
-
[CrossRef]
-
Li, J.; Dong, Y.; Hao, G.; Wang, B.; Wang, J.; Liang, Y.; Liu, Y.; Zhen, E.; Feng, D.; Liang, G. Naringin suppresses the development of glioblastoma by inhibiting FAK activity. J. Drug Target. 2016. [CrossRef]
-
(2016)
J. Drug Target
-
-
Li, J.1
Dong, Y.2
Hao, G.3
Wang, B.4
Wang, J.5
Liang, Y.6
Liu, Y.7
Zhen, E.8
Feng, D.9
Liang, G.10
-
139
-
-
33745700890
-
Suppression of colon carcinogenesis by bioactive compounds in grapefruit
-
Vanamala, J.; Leonardi, T.; Patil, B.S.; Taddeo, S.S.; Murphy, M.E.; Pike, L.M.; Chapkin, R.S.; Lupton, J.R.; Turner, N.D. Suppression of colon carcinogenesis by bioactive compounds in grapefruit. Carcinogenesis 2006, 27, 1257–1265.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1257-1265
-
-
Vanamala, J.1
Leonardi, T.2
Patil, B.S.3
Taddeo, S.S.4
Murphy, M.E.5
Pike, L.M.6
Chapkin, R.S.7
Lupton, J.R.8
Turner, N.D.9
-
140
-
-
84855656512
-
Naringin inhibits tumor growth and reduces interleukin-6 and tumor necrosis factor alpha levels in rats with Walker 256 carcinosarcoma
-
Camargo, C.A.; Gomes-Marcondes, M.C.C.; Wutzki, N.C.; Aoyama, H. Naringin inhibits tumor growth and reduces interleukin-6 and tumor necrosis factor alpha levels in rats with Walker 256 carcinosarcoma. Anticancer Res. 2012, 32, 129–133.
-
(2012)
Anticancer Res
, vol.32
, pp. 129-133
-
-
Camargo, C.A.1
Gomes-Marcondes, M.C.C.2
Wutzki, N.C.3
Aoyama, H.4
-
141
-
-
84951752111
-
Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc(Min/+) mouse model
-
Zhang, Y.S.; Li, Y.; Wang, Y.; Sun, S.Y.; Jiang, T.; Li, C.; Cui, S.X.; Qu, X.J. Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc(min/+) mouse model. J. Cancer Res. Clin. Oncol. 2016, 142, 913–925.
-
(2016)
J. Cancer Res. Clin. Oncol
, vol.142
, pp. 913-925
-
-
Zhang, Y.S.1
Li, Y.2
Wang, Y.3
Sun, S.Y.4
Jiang, T.5
Li, C.6
Cui, S.X.7
Qu, X.J.8
-
142
-
-
0035667114
-
Chemistry and pharmacology of the Citrus bioflavonoid hesperidin
-
Garg, A.; Garg, S.; Zaneveld, L.J.; Singla, A.K. Chemistry and pharmacology of the Citrus bioflavonoid hesperidin. Phytother. Res. 2001, 15, 655–669.
-
(2001)
Phytother. Res
, vol.15
, pp. 655-669
-
-
Garg, A.1
Garg, S.2
Zaneveld, L.J.3
Singla, A.K.4
-
143
-
-
0141852379
-
Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids. Biochem
-
Chen, Y.C.; Shen, S.C.; Lin, H.Y. Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids. Biochem. Pharmacol. 2003, 66, 1139–1150.
-
(2003)
Pharmacol
, vol.66
, pp. 1139-1150
-
-
Chen, Y.C.1
Shen, S.C.2
Lin, H.Y.3
-
144
-
-
35148840445
-
Hesperetin induced G1-phase cell cycle arrest in human breast cancer MCF-7 cells: Involvement of CDK4 and p21
-
Choi, E.J. Hesperetin induced G1-phase cell cycle arrest in human breast cancer MCF-7 cells: Involvement of CDK4 and p21. Nutr. Cancer Int. J. 2007, 59, 115–119.
-
(2007)
Nutr. Cancer Int. J
, vol.59
, pp. 115-119
-
-
Choi, E.J.1
-
145
-
-
84857957407
-
Role of hesperetin (A natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line—A comparative study
-
Sivagami, G.; Vinothkumar, R.; Preethy, C.P.; Riyasdeen, A.; Akbarsha, M.A.; Menon, V.P.; Nalini, N. Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line—A comparative study. Food Chem. Toxicol. 2012, 50, 660–671.
-
(2012)
Food Chem. Toxicol
, vol.50
, pp. 660-671
-
-
Sivagami, G.1
Vinothkumar, R.2
Preethy, C.P.3
Riyasdeen, A.4
Akbarsha, M.A.5
Menon, V.P.6
Nalini, N.7
-
146
-
-
79952174816
-
Hesperetin, a potential therapy for carcinoid cancer
-
Zarebczan, B.; Pinchot, S.N.; Kunnimalaiyaan, M.; Chen, H. Hesperetin, a potential therapy for carcinoid cancer. Am. J. Surg. 2011, 201, 329–333.
-
(2011)
Am. J. Surg
, vol.201
, pp. 329-333
-
-
Zarebczan, B.1
Pinchot, S.N.2
Kunnimalaiyaan, M.3
Chen, H.4
-
147
-
-
84886597627
-
The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways
-
Alshatwi, A.A.; Ramesh, E.; Periasamy, V.S.; Subash-Babu, P. The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways. Fundam. Clin. Pharmacol. 2013, 27, 581–592.
-
(2013)
Fundam. Clin. Pharmacol
, vol.27
, pp. 581-592
-
-
Alshatwi, A.A.1
Ramesh, E.2
Periasamy, V.S.3
Subash-Babu, P.4
-
148
-
-
84924150405
-
Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP and calcium
-
[CrossRef]
-
Zhang, J.; Song, J.; Wu, D.; Wang, J.; Dong, W. Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP and calcium. Med. Oncol. 2015, 32, 101. [CrossRef]
-
(2015)
Med. Oncol
, vol.32
, pp. 101
-
-
Zhang, J.1
Song, J.2
Wu, D.3
Wang, J.4
Dong, W.5
-
149
-
-
84879976165
-
Antiproliferative efficacy of hesperetin (Citrus flavanoid) in 1,2-dimethylhydrazineinduced colon cancer
-
Aranganathan, S.; Nalini, N. Antiproliferative efficacy of hesperetin (Citrus flavanoid) in 1,2-dimethylhydrazineinduced colon cancer. Phytother. Res. 2013, 27, 999–1005.
-
(2013)
Phytother. Res
, vol.27
, pp. 999-1005
-
-
Aranganathan, S.1
Nalini, N.2
-
150
-
-
84860856963
-
Chemopreventive efficacy of hesperetin (Citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis
-
Nalini, N.; Aranganathan, S.; Kabalimurthy, J. Chemopreventive efficacy of hesperetin (Citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Toxicol. Mech. Methods 2012, 22, 397–408.
-
(2012)
Toxicol. Mech. Methods
, vol.22
, pp. 397-408
-
-
Nalini, N.1
Aranganathan, S.2
Kabalimurthy, J.3
-
151
-
-
72449199438
-
Bioactive compounds from mexican lime (Citrus aurantifolia) juice induce apoptosis in human pancreatic cells
-
Patil, J.R.; Murthy, K.N.C.; Jayaprakasha, G.K.; Chetti, M.B.; Patil, B.S. Bioactive compounds from mexican lime (Citrus aurantifolia) juice induce apoptosis in human pancreatic cells. J. Agric. Food Chem. 2009, 57, 10933–10942.
-
(2009)
J. Agric. Food Chem
, vol.57
, pp. 10933-10942
-
-
Patil, J.R.1
Murthy, K.N.C.2
Jayaprakasha, G.K.3
Chetti, M.B.4
Patil, B.S.5
-
152
-
-
37349110272
-
Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4
-
Park, H.J.; Kim, M.J.; Ha, E.; Chung, J.H. Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4. Phytomedicine 2008, 15, 147–151.
-
(2008)
Phytomedicine
, vol.15
, pp. 147-151
-
-
Park, H.J.1
Kim, M.J.2
Ha, E.3
Chung, J.H.4
-
153
-
-
84937622393
-
Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways
-
Banjerdpongchai, R.; Wudtiwai, B.; Khaw-On, P.; Rachakhom, W.; Duangnil, N.; Kongtawelert, P. Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways. Tumour Biol. 2016, 37, 227–237.
-
(2016)
Tumour Biol
, vol.37
, pp. 227-237
-
-
Banjerdpongchai, R.1
Wudtiwai, B.2
Khaw-On, P.3
Rachakhom, W.4
Duangnil, N.5
Kongtawelert, P.6
-
154
-
-
84903592219
-
Hesperidin induces paraptosis like cell death in hepatoblastoma, hepg2 cells: Involvement of ERK1/2 MAPK
-
Yumnam, S.; Park, H.S.; Kim, M.K.; Nagappan, A.; Hong, G.E.; Lee, H.J.; Lee, W.S.; Kim, E.H.; Cho, J.H.; Shin, S.C.; et al. Hesperidin induces paraptosis like cell death in hepatoblastoma, hepg2 cells: Involvement of ERK1/2 MAPK. PLoS ONE 2014, 9, e101321.
-
(2014)
PLoS ONE
, vol.9
-
-
Yumnam, S.1
Park, H.S.2
Kim, M.K.3
Nagappan, A.4
Hong, G.E.5
Lee, H.J.6
Lee, W.S.7
Kim, E.H.8
Cho, J.H.9
Shin, S.C.10
-
155
-
-
78651069319
-
Inactivation of nuclear factor-κB by Citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in ramos cells
-
Nazari, M.; Ghorbani, A.; Hekmat-Doost, A.; Jeddi-Tehrani, M.; Zand, H. Inactivation of nuclear factor-κB by Citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in ramos cells. Eur. J. Pharmacol. 2011, 650, 526–533.
-
(2011)
Eur. J. Pharmacol
, vol.650
, pp. 526-533
-
-
Nazari, M.1
Ghorbani, A.2
Hekmat-Doost, A.3
Jeddi-Tehrani, M.4
Zand, H.5
-
156
-
-
84859886313
-
The Citrus flavonoid hesperidin induces p53 and inhibits NF-kB activation in order to trigger apoptosis in NALM-6 cells: Involvement of ppar gamma-dependent mechanism
-
Ghorbani, A.; Nazari, M.; Jeddi-Tehrani, M.; Zand, H. The Citrus flavonoid hesperidin induces p53 and inhibits NF-kB activation in order to trigger apoptosis in NALM-6 cells: Involvement of ppar gamma-dependent mechanism. Eur. J. Nutr. 2012, 51, 39–46.
-
(2012)
Eur. J. Nutr
, vol.51
, pp. 39-46
-
-
Ghorbani, A.1
Nazari, M.2
Jeddi-Tehrani, M.3
Zand, H.4
-
157
-
-
84928393491
-
Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway
-
Palit, S.; Kar, S.; Sharma, G.; Das, P.K. Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway. J. Cell. Physiol. 2015, 230, 1729–1739.
-
(2015)
J. Cell. Physiol
, vol.230
, pp. 1729-1739
-
-
Palit, S.1
Kar, S.2
Sharma, G.3
Das, P.K.4
-
158
-
-
83655203192
-
Effect of flavonone hesperidin on the apoptosis of human mammary carcinoma cell line MCF-7
-
Natarajan, N.; Thamaraiselvan, R.; Lingaiah, H.; Srinivasan, P.; Periyasamy, B.M. Effect of flavonone hesperidin on the apoptosis of human mammary carcinoma cell line MCF-7. Biomed. Prev. Nutr. 2011, 1, 207–215.
-
(2011)
Biomed. Prev. Nutr
, vol.1
, pp. 207-215
-
-
Natarajan, N.1
Thamaraiselvan, R.2
Lingaiah, H.3
Srinivasan, P.4
Periyasamy, B.M.5
-
159
-
-
84944065622
-
Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest
-
[CrossRef]
-
Wang, Y.X.; Yu, H.; Zhang, J.; Gao, J.; Ge, X.; Lou, G. Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest. BMC Cancer 2015, 15. [CrossRef]
-
(2015)
BMC Cancer
, vol.15
-
-
Wang, Y.X.1
Yu, H.2
Zhang, J.3
Gao, J.4
Ge, X.5
Lou, G.6
-
160
-
-
70649091119
-
Inhibition of p-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines
-
[PubMed]
-
El-Readi, M.Z.; Hamdan, D.; Farrag, N.; El-Shazly, A.; Wink, M. Inhibition of p-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines. Eur. J. Pharmacol. 2010, 626, 139–145. [PubMed]
-
(2010)
Eur. J. Pharmacol
, vol.626
, pp. 139-145
-
-
El-Readi, M.Z.1
Hamdan, D.2
Farrag, N.3
El-Shazly, A.4
Wink, M.5
-
161
-
-
1642504340
-
Interaction of the breast cancer resistance protein with plant polyphenols
-
Cooray, H.C.; Janvilisri, T.; van Veen, H.W.; Hladky, S.B.; Barrand, M.A. Interaction of the breast cancer resistance protein with plant polyphenols. Biochem. Biophys. Res. Commun. 2004, 317, 269–275.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.317
, pp. 269-275
-
-
Cooray, H.C.1
Janvilisri, T.2
Van Veen, H.W.3
Hladky, S.B.4
Barrand, M.A.5
-
162
-
-
75749123418
-
Hesperidin suppressed proliferations of both human breast cancer and androgen-dependent prostate cancer cells
-
Lee, C.J.; Wilson, L.; Jordan, M.A.; Nguyen, V.; Tang, J.; Smiyun, G. Hesperidin suppressed proliferations of both human breast cancer and androgen-dependent prostate cancer cells. Phytother. Res. 2010, 24, S15–S19.
-
(2010)
Phytother. Res
, vol.24
, pp. S15-S19
-
-
Lee, C.J.1
Wilson, L.2
Jordan, M.A.3
Nguyen, V.4
Tang, J.5
Smiyun, G.6
-
163
-
-
0027934285
-
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin—Comparison with the protective effect of beta-carotene
-
Tanaka, T.; Makita, H.; Ohnishi, M.; Hirose, Y.; Wang, A.J.; Mori, H.; Satoh, K.; Hara, A.; Ogawa, H. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin—Comparison with the protective effect of beta-carotene. Cancer Res. 1994, 54, 4653–4659.
-
(1994)
Cancer Res
, vol.54
, pp. 4653-4659
-
-
Tanaka, T.1
Makita, H.2
Ohnishi, M.3
Hirose, Y.4
Wang, A.J.5
Mori, H.6
Satoh, K.7
Hara, A.8
Ogawa, H.9
-
164
-
-
0031666252
-
Inhibitory effect of hesperidin on tumour initiation and promotion in mouse skin
-
Berkarda, B.; Koyuncu, H.; Soybir, G.; Baykut, F. Inhibitory effect of hesperidin on tumour initiation and promotion in mouse skin. Res. Exp. Med. 1998, 198, 93–99.
-
(1998)
Res. Exp. Med
, vol.198
, pp. 93-99
-
-
Berkarda, B.1
Koyuncu, H.2
Soybir, G.3
Baykut, F.4
-
165
-
-
0033451024
-
Preventive effect of hesperidin against inflammation in CD-1 mouse skin caused by tumor promoter
-
Koyuncu, H.; Berkarda, B.; Baykut, F.; Soybir, G.; Alatli, C.; Gul, H.; Altun, M. Preventive effect of hesperidin against inflammation in CD-1 mouse skin caused by tumor promoter. Anticancer Res. 1999, 19, 3237–3241.
-
(1999)
Anticancer Res
, vol.19
, pp. 3237-3241
-
-
Koyuncu, H.1
Berkarda, B.2
Baykut, F.3
Soybir, G.4
Alatli, C.5
Gul, H.6
Altun, M.7
-
166
-
-
69549105653
-
Efficacy of the potential chemopreventive agent, hesperetin (Citrus flavanone), on 1,2-dimethylhydrazine induced colon carcinogenesis. Food
-
Aranganathan, S.; Nalini, N. Efficacy of the potential chemopreventive agent, hesperetin (Citrus flavanone), on 1,2-dimethylhydrazine induced colon carcinogenesis. Food Chem. Toxicol. 2009, 47, 2594–2600.
-
(2009)
Chem. Toxicol
, vol.47
, pp. 2594-2600
-
-
Aranganathan, S.1
Nalini, N.2
-
167
-
-
78651354623
-
Anti-/pro-apoptotic effects of hesperetin against 7,12-dimetylbenz(A)anthraceneinduced alteration in animals
-
Choi, E.J.; Kim, G.H. Anti-/pro-apoptotic effects of hesperetin against 7,12-dimetylbenz(a)anthraceneinduced alteration in animals. Oncol. Rep. 2011, 25, 545–550.
-
(2011)
Oncol. Rep
, vol.25
, pp. 545-550
-
-
Choi, E.J.1
Kim, G.H.2
-
168
-
-
64649106457
-
Antioxidant and anticancer efficacy of hesperidin in benzo(A)pyrene induced lung carcinogenesis in mice
-
Kamaraj, S.; Ramakrishnan, G.; Anandakumar, P.; Jagan, S.; Devaki, T. Antioxidant and anticancer efficacy of hesperidin in benzo(a)pyrene induced lung carcinogenesis in mice. Investig. New Drugs 2009, 27, 214–222.
-
(2009)
Investig. New Drugs
, vol.27
, pp. 214-222
-
-
Kamaraj, S.1
Ramakrishnan, G.2
Anandakumar, P.3
Jagan, S.4
Devaki, T.5
-
169
-
-
84866323013
-
The Citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice
-
Ye, L.; Chan, F.L.; Chen, S.A.; Leung, L.K. The Citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice. J. Nutr. Biochem. 2012, 23, 1230–1237.
-
(2012)
J. Nutr. Biochem
, vol.23
, pp. 1230-1237
-
-
Ye, L.1
Chan, F.L.2
Chen, S.A.3
Leung, L.K.4
-
170
-
-
77952553455
-
Didymin, a dietary flavonoid glycoside from Citrus fruits, induces FAS-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo
-
Hung, J.Y.; Hsu, Y.L.; Ko, Y.C.; Tsai, Y.M.; Yang, C.J.; Huang, M.S.; Kuo, P.L. Didymin, a dietary flavonoid glycoside from Citrus fruits, induces FAS-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo. Lung Cancer 2010, 68, 366–374.
-
(2010)
Lung Cancer
, vol.68
, pp. 366-374
-
-
Hung, J.Y.1
Hsu, Y.L.2
Ko, Y.C.3
Tsai, Y.M.4
Yang, C.J.5
Huang, M.S.6
Kuo, P.L.7
-
171
-
-
84942163058
-
Poncirin induces apoptosis in AGS human gastric cancer cells through extrinsic apoptotic pathway by up-regulation of FAS ligand
-
Saralamma, V.V.G.; Nagappan, A.; Hong, G.E.; Lee, H.J.; Yumnam, S.; Raha, S.; Heo, J.D.; Lee, S.J.; Lee, W.S.; Kim, E.H.; et al. Poncirin induces apoptosis in AGS human gastric cancer cells through extrinsic apoptotic pathway by up-regulation of FAS ligand. Int. J. Mol. Sci. 2015, 16, 22676–22691.
-
(2015)
Int. J. Mol. Sci
, vol.16
, pp. 22676-22691
-
-
Saralamma, V.V.G.1
Nagappan, A.2
Hong, G.E.3
Lee, H.J.4
Yumnam, S.5
Raha, S.6
Heo, J.D.7
Lee, S.J.8
Lee, W.S.9
Kim, E.H.10
-
172
-
-
51349128983
-
Anthocyanins and their role in cancer prevention
-
Wang, L.S.; Stoner, G.D. Anthocyanins and their role in cancer prevention. Cancer Lett. 2008, 269, 281–290.
-
(2008)
Cancer Lett
, vol.269
, pp. 281-290
-
-
Wang, L.S.1
Stoner, G.D.2
-
173
-
-
33646812944
-
Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells
-
Schindler, R.; Mentlein, R. Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells. J. Nutr. 2006, 136, 1477–1482.
-
(2006)
J. Nutr
, vol.136
, pp. 1477-1482
-
-
Schindler, R.1
Mentlein, R.2
-
174
-
-
79957875674
-
Flavonoids inhibit angiogenic cytokine production by human glioma cells
-
Freitas, S.; Costa, S.; Azevedo, C.; Carvalho, G.; Freire, S.; Barbosa, P.; Velozo, E.; Schaer, R.; Tardy, M.; Meyer, R.; et al. Flavonoids inhibit angiogenic cytokine production by human glioma cells. Phytother. Res. 2011, 25, 916–921.
-
(2011)
Phytother. Res
, vol.25
, pp. 916-921
-
-
Freitas, S.1
Costa, S.2
Azevedo, C.3
Carvalho, G.4
Freire, S.5
Barbosa, P.6
Velozo, E.7
Schaer, R.8
Tardy, M.9
Meyer, R.10
-
175
-
-
23944521126
-
Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: Implication of chemoprevention of lung cancer
-
Liu, L.Z.; Fang, J.; Zhou, Q.; Hu, X.W.; Shi, X.L.; Jiang, B.H. Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: Implication of chemoprevention of lung cancer. Mol. Pharmacol. 2005, 68, 635–643.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 635-643
-
-
Liu, L.Z.1
Fang, J.2
Zhou, Q.3
Hu, X.W.4
Shi, X.L.5
Jiang, B.H.6
-
176
-
-
34047132303
-
Apigenin inhibits tumor angiogenesis through decreasing HIF-1 alpha and VEGF expression
-
Fang, J.; Zhou, Q.; Liu, L.Z.; Xia, C.; Hu, X.W.; Shi, X.L.; Jiang, B.H. Apigenin inhibits tumor angiogenesis through decreasing HIF-1 alpha and VEGF expression. Carcinogenesis 2007, 28, 858–864.
-
(2007)
Carcinogenesis
, vol.28
, pp. 858-864
-
-
Fang, J.1
Zhou, Q.2
Liu, L.Z.3
Xia, C.4
Hu, X.W.5
Shi, X.L.6
Jiang, B.H.7
-
177
-
-
0038022616
-
Flavonoids inhibit VEGF/BFGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases
-
Kim, M.H. Flavonoids inhibit VEGF/BFGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases. J. Cell. Biochem. 2003, 89, 529–538.
-
(2003)
J. Cell. Biochem
, vol.89
, pp. 529-538
-
-
Kim, M.H.1
-
178
-
-
84862010246
-
Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/Stat3 pathway
-
Lamy, S.; Akla, N.; Ouanouki, A.; Lord-Dufour, S.; Beliveau, R. Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/Stat3 pathway. Exp. Cell Res. 2012, 318, 1586–1596.
-
(2012)
Exp. Cell Res
, vol.318
, pp. 1586-1596
-
-
Lamy, S.1
Akla, N.2
Ouanouki, A.3
Lord-Dufour, S.4
Beliveau, R.5
-
179
-
-
84862526674
-
In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: Identifying sinensetin as a novel antiangiogenesis agent
-
Lam, I.K.; Alex, D.; Wang, Y.H.; Liu, P.; Liu, A.L.; Du, G.H.; Lee, S.M. In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: Identifying sinensetin as a novel antiangiogenesis agent. Mol. Nutr. Food Res. 2012, 56, 945–956.
-
(2012)
Mol. Nutr. Food Res
, vol.56
, pp. 945-956
-
-
Lam, I.K.1
Alex, D.2
Wang, Y.H.3
Liu, P.4
Liu, A.L.5
Du, G.H.6
Lee, S.M.7
-
180
-
-
77958611254
-
Nobiletin, a Citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo
-
Kunimasa, K.; Ikekita, M.; Sato, M.; Ohta, T.; Yamori, Y.; Ikeda, M.; Kuranuki, S.; Oikawa, T. Nobiletin, a Citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo. Cancer Sci. 2010, 101, 2462–2469.
-
(2010)
Cancer Sci
, vol.101
, pp. 2462-2469
-
-
Kunimasa, K.1
Ikekita, M.2
Sato, M.3
Ohta, T.4
Yamori, Y.5
Ikeda, M.6
Kuranuki, S.7
Oikawa, T.8
-
181
-
-
69749089240
-
Effect of nobiletin on K562 cells xenograft in nude mice
-
Wang, Y.; Su, M.; Yin, J.; Zhang, H. Effect of nobiletin on K562 cells xenograft in nude mice. Zhongguo Zhong Yao Za Zhi 2009, 34, 1410–1414.
-
(2009)
Zhongguo Zhong Yao Za Zhi
, vol.34
, pp. 1410-1414
-
-
Wang, Y.1
Su, M.2
Yin, J.3
Zhang, H.4
-
182
-
-
0037449461
-
Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential
-
Tan, W.F.; Lin, L.P.; Li, M.H.; Zhang, Y.X.; Tong, Y.G.; Xiao, D.; Ding, J. Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential. Eur. J. Pharmacol. 2003, 459, 255–262.
-
(2003)
Eur. J. Pharmacol
, vol.459
, pp. 255-262
-
-
Tan, W.F.1
Lin, L.P.2
Li, M.H.3
Zhang, Y.X.4
Tong, Y.G.5
Xiao, D.6
Ding, J.7
-
183
-
-
67649086164
-
Correlation between antiangiogenic activity and antioxidant activity of various components from propolis
-
Ahn, M.R.; Kunimasa, K.; Kumazawa, S.; Nakayama, T.; Kaji, K.; Uto, Y.; Hori, H.; Nagasawa, H.; Ohta, T. Correlation between antiangiogenic activity and antioxidant activity of various components from propolis. Mol. Nutr. Food Res. 2009, 53, 643–651.
-
(2009)
Mol. Nutr. Food Res
, vol.53
, pp. 643-651
-
-
Ahn, M.R.1
Kunimasa, K.2
Kumazawa, S.3
Nakayama, T.4
Kaji, K.5
Uto, Y.6
Hori, H.7
Nagasawa, H.8
Ohta, T.9
-
184
-
-
84862309686
-
Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities
-
Weng, C.J.; Yen, G.C. Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. Cancer Metastas. Rev. 2012, 31, 323–351.
-
(2012)
Cancer Metastas. Rev
, vol.31
, pp. 323-351
-
-
Weng, C.J.1
Yen, G.C.2
-
185
-
-
0035989520
-
The Citrus methoxyflavone tangeretin affects human cell-cell interactions
-
Bracke, M.E.; Boterberg, T.; Depypere, H.T.; Stove, C.; Leclercq, G.; Mareel, M.M. The Citrus methoxyflavone tangeretin affects human cell-cell interactions. Flavonoids Cell Funct. 2002, 505, 135–139.
-
(2002)
Flavonoids Cell Funct
, vol.505
, pp. 135-139
-
-
Bracke, M.E.1
Boterberg, T.2
Depypere, H.T.3
Stove, C.4
Leclercq, G.5
Mareel, M.M.6
-
186
-
-
84903763252
-
Naringin suppress chondrosarcoma migration through inhibition vascular adhesion molecule-1 expression by modulating mir-126
-
Tan, T.W.; Chou, Y.E.; Yang, W.H.; Hsu, C.J.; Fong, Y.C.; Tang, C.H. Naringin suppress chondrosarcoma migration through inhibition vascular adhesion molecule-1 expression by modulating mir-126. Int. Immunopharmacol. 2014, 22, 107–114.
-
(2014)
Int. Immunopharmacol
, vol.22
, pp. 107-114
-
-
Tan, T.W.1
Chou, Y.E.2
Yang, W.H.3
Hsu, C.J.4
Fong, Y.C.5
Tang, C.H.6
-
187
-
-
84905502744
-
Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP-2
-
Liao, A.C.H.; Kuo, C.C.; Huang, Y.C.; Yeh, C.W.; Hseu, Y.C.; Liu, J.Y.; Hsu, L.S. Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP-2. Mol. Med. Rep. 2014, 10, 1531–1536.
-
(2014)
Mol. Med. Rep
, vol.10
, pp. 1531-1536
-
-
Liao, A.C.H.1
Kuo, C.C.2
Huang, Y.C.3
Yeh, C.W.4
Hseu, Y.C.5
Liu, J.Y.6
Hsu, L.S.7
-
188
-
-
24344497767
-
Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin
-
Martinez Conesa, C.; Vicente Ortega, V.; Yanez Gascon, M.J.; Alcaraz Banos, M.; Canteras Jordana, M.; Benavente-Garcia, O.; Castillo, J. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. J. Agric. Food Chem. 2005, 53, 6791–6797.
-
(2005)
J. Agric. Food Chem
, vol.53
, pp. 6791-6797
-
-
Martinez Conesa, C.1
Vicente Ortega, V.2
Yanez Gascon, M.J.3
Alcaraz Banos, M.4
Canteras Jordana, M.5
Benavente-Garcia, O.6
Castillo, J.7
-
189
-
-
33845266497
-
Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential
-
Lentini, A.; Forni, C.; Provenzano, B.; Beninati, S. Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential. Amino Acids 2007, 32, 95–100.
-
(2007)
Amino Acids
, vol.32
, pp. 95-100
-
-
Lentini, A.1
Forni, C.2
Provenzano, B.3
Beninati, S.4
-
190
-
-
80053082680
-
Naringenin reduces lung metastasis in a breast cancer resection model
-
Qin, L.; Jin, L.T.; Lu, L.L.; Lu, X.Y.; Zhang, C.L.; Zhang, F.Y.; Liang, W. Naringenin reduces lung metastasis in a breast cancer resection model. Protein Cell 2011, 2, 507–516.
-
(2011)
Protein Cell
, vol.2
, pp. 507-516
-
-
Qin, L.1
Jin, L.T.2
Lu, L.L.3
Lu, X.Y.4
Zhang, C.L.5
Zhang, F.Y.6
Liang, W.7
-
191
-
-
37349052385
-
A Citrus polymethoxyflavonoid, nobiletin, is a novel mek inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells
-
Miyata, Y.; Sato, T.; Imada, K.; Dobashi, A.; Yano, M.; Ito, A. A Citrus polymethoxyflavonoid, nobiletin, is a novel mek inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells. Biochem. Biophys. Res. Commun. 2008, 366, 168–173.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.366
, pp. 168-173
-
-
Miyata, Y.1
Sato, T.2
Imada, K.3
Dobashi, A.4
Yano, M.5
Ito, A.6
-
192
-
-
0036173982
-
Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and-9 in human fibrosarcoma HT-1080 cells
-
Sato, T.; Koike, L.; Miyata, Y.; Hirata, M.; Mimaki, Y.; Sashida, Y.; Yano, M.; Ito, A. Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and-9 in human fibrosarcoma HT-1080 cells. Cancer Res. 2002, 62, 1025–1029.
-
(2002)
Cancer Res
, vol.62
, pp. 1025-1029
-
-
Sato, T.1
Koike, L.2
Miyata, Y.3
Hirata, M.4
Mimaki, Y.5
Sashida, Y.6
Yano, M.7
Ito, A.8
-
193
-
-
15744366938
-
Nobiletin, a Citrus flavonoid, down-regulates matrix metalloproteinase-7 (Matrilysin) expression in HT-29 human colorectal cancer cells
-
Kawabata, K.; Murakami, A.; Ohigashi, H. Nobiletin, a Citrus flavonoid, down-regulates matrix metalloproteinase-7 (matrilysin) expression in HT-29 human colorectal cancer cells. Biosci. Biotechnol. Biochem. 2005, 69, 307–314.
-
(2005)
Biosci. Biotechnol. Biochem
, vol.69
, pp. 307-314
-
-
Kawabata, K.1
Murakami, A.2
Ohigashi, H.3
-
194
-
-
84923079808
-
Nobiletin inhibits invasion and migration of human nasopharyngeal carcinoma cell lines by involving ERK1/2 and transcriptional inhibition of MMP-2
-
Chien, S.Y.; Hsieh, M.J.; Chen, C.J.; Yang, S.F.; Chen, M.K. Nobiletin inhibits invasion and migration of human nasopharyngeal carcinoma cell lines by involving ERK1/2 and transcriptional inhibition of MMP-2. Expert Opin. Ther. Targets 2015, 19, 307–320.
-
(2015)
Expert Opin. Ther. Targets
, vol.19
, pp. 307-320
-
-
Chien, S.Y.1
Hsieh, M.J.2
Chen, C.J.3
Yang, S.F.4
Chen, M.K.5
-
195
-
-
84866072453
-
Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9
-
Baek, S.H.; Kim, S.M.; Nam, D.; Lee, J.H.; Ahn, K.S.; Choi, S.H.; Kim, S.H.; Shim, B.S.; Chang, I.M.; Ahn, K.S. Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9. Pharm. Biol. 2012, 50, 1210–1218.
-
(2012)
Pharm. Biol
, vol.50
, pp. 1210-1218
-
-
Baek, S.H.1
Kim, S.M.2
Nam, D.3
Lee, J.H.4
Ahn, K.S.5
Choi, S.H.6
Kim, S.H.7
Shim, B.S.8
Chang, I.M.9
Ahn, K.S.10
-
196
-
-
0035673312
-
The Citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice
-
Minagawa, A.; Otani, Y.; Kubota, T.; Wada, N.; Furukawa, T.; Kumai, K.; Kameyama, K.; Okada, Y.; Fujii, M.; Yano, M.; et al. The Citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice. Jpn. J. Cancer Res. 2001, 92, 1322–1328.
-
(2001)
Jpn. J. Cancer Res
, vol.92
, pp. 1322-1328
-
-
Minagawa, A.1
Otani, Y.2
Kubota, T.3
Wada, N.4
Furukawa, T.5
Kumai, K.6
Kameyama, K.7
Okada, Y.8
Fujii, M.9
Yano, M.10
-
197
-
-
78651303014
-
Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/AKT and small GTPase signals in human gastric adenocarcinoma AGS cells
-
Lee, Y.C.; Cheng, T.H.; Lee, J.S.; Chen, J.H.; Liao, Y.C.; Fong, Y.; Wu, C.H.; Shih, Y.W. Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/AKT and small GTPase signals in human gastric adenocarcinoma AGS cells. Mol. Cell. Biochem. 2011, 347, 103–115.
-
(2011)
Mol. Cell. Biochem
, vol.347
, pp. 103-115
-
-
Lee, Y.C.1
Cheng, T.H.2
Lee, J.S.3
Chen, J.H.4
Liao, Y.C.5
Fong, Y.6
Wu, C.H.7
Shih, Y.W.8
-
198
-
-
84964054338
-
Nobiletin inhibits epithelial-mesenchymal transition of human non-small cell lung cancer cells by antagonizing the TGF-BETA1/SMAD3 signaling pathway
-
Da, C.; Liu, Y.; Zhan, Y.; Liu, K.; Wang, R. Nobiletin inhibits epithelial-mesenchymal transition of human non-small cell lung cancer cells by antagonizing the TGF-BETA1/SMAD3 signaling pathway. Oncol. Rep. 2016, 35, 2767–2774.
-
(2016)
Oncol. Rep
, vol.35
, pp. 2767-2774
-
-
Da, C.1
Liu, Y.2
Zhan, Y.3
Liu, K.4
Wang, R.5
-
199
-
-
0034819073
-
Apigenin acts on the tumor cell invasion process and regulates protease production
-
Lindenmeyer, F.; Li, H.; Menashi, S.; Soria, C.; Lu, H. Apigenin acts on the tumor cell invasion process and regulates protease production. Nutr. Cancer Int. J. 2001, 39, 139–147.
-
(2001)
Nutr. Cancer Int. J
, vol.39
, pp. 139-147
-
-
Lindenmeyer, F.1
Li, H.2
Menashi, S.3
Soria, C.4
Lu, H.5
-
200
-
-
37349021728
-
Apigenin inhibits hgf-promoted invasive growth and metastasis involving blocking PI3K/AKT pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells
-
Lee, W.J.; Chen, W.K.; Wang, C.J.; Lin, W.L.; Tseng, T.H. Apigenin inhibits hgf-promoted invasive growth and metastasis involving blocking PI3K/AKT pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells. Toxicol. Appl. Pharmacol. 2008, 226, 178–191.
-
(2008)
Toxicol. Appl. Pharmacol
, vol.226
, pp. 178-191
-
-
Lee, W.J.1
Chen, W.K.2
Wang, C.J.3
Lin, W.L.4
Tseng, T.H.5
-
201
-
-
70449711373
-
The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prev
-
Franzen, C.A.; Amargo, E.; Todorovic, V.; Desai, B.V.; Huda, S.; Mirzoeva, S.; Chiu, K.; Grzybowski, B.A.; Chew, T.L.; Green, K.J.; et al. The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prev. Res. 2009, 2, 830–841.
-
(2009)
Res
, vol.2
, pp. 830-841
-
-
Franzen, C.A.1
Amargo, E.2
Todorovic, V.3
Desai, B.V.4
Huda, S.5
Mirzoeva, S.6
Chiu, K.7
Grzybowski, B.A.8
Chew, T.L.9
Green, K.J.10
-
202
-
-
57349181198
-
Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase
-
Hu, X.W.; Meng, D.; Fang, J. Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase. Carcinogenesis 2008, 29, 2369–2376.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2369-2376
-
-
Hu, X.W.1
Meng, D.2
Fang, J.3
-
203
-
-
13244277580
-
Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro
-
Czyz, J.; Madeja, Z.; Irmer, U.; Korohoda, W.; Hulser, D.F. Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro. Int. J. Cancer 2005, 114, 12–18.
-
(2005)
Int. J. Cancer
, vol.114
, pp. 12-18
-
-
Czyz, J.1
Madeja, Z.2
Irmer, U.3
Korohoda, W.4
Hulser, D.F.5
-
204
-
-
0035687569
-
Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in wistar rats
-
Tatsuta, M.; Iishi, H.; Baba, M.; Yano, H.; Murata, K.; Mukai, M.; Akedo, H. Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in wistar rats. Clin. Exp. Metastas. 2001, 18, 657–662.
-
(2001)
Clin. Exp. Metastas
, vol.18
, pp. 657-662
-
-
Tatsuta, M.1
Iishi, H.2
Baba, M.3
Yano, H.4
Murata, K.5
Mukai, M.6
Akedo, H.7
-
205
-
-
77953009188
-
Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by apigenin via the inhibition of p38 mitogen-activated protein kinase-dependent matrix metalloproteinase-9 expression
-
Noh, H.J.; Sung, E.G.; Kim, J.Y.; Lee, T.J.; Song, I.H. Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by apigenin via the inhibition of p38 mitogen-activated protein kinase-dependent matrix metalloproteinase-9 expression. Oncol. Rep. 2010, 24, 277–283.
-
(2010)
Oncol. Rep
, vol.24
, pp. 277-283
-
-
Noh, H.J.1
Sung, E.G.2
Kim, J.Y.3
Lee, T.J.4
Song, I.H.5
-
206
-
-
0033873786
-
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential
-
Caltagirone, S.; Rossi, C.; Poggi, A.; Ranelletti, F.O.; Natali, P.G.; Brunetti, M.; Aiello, F.B.; Piantelli, M. Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential. Int. J. Cancer 2000, 87, 595–600.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 595-600
-
-
Caltagirone, S.1
Rossi, C.2
Poggi, A.3
Ranelletti, F.O.4
Natali, P.G.5
Brunetti, M.6
Aiello, F.B.7
Piantelli, M.8
-
207
-
-
51849133195
-
Quercetin inhibition of tumor invasion via suppressing PKC DELTA/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells
-
Lin, C.W.; Hou, W.C.; Shen, S.C.; Juan, S.H.; Ko, C.H.; Wang, L.M.; Chen, Y.C. Quercetin inhibition of tumor invasion via suppressing PKC DELTA/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells. Carcinogenesis 2008, 29, 1807–1815.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1807-1815
-
-
Lin, C.W.1
Hou, W.C.2
Shen, S.C.3
Juan, S.H.4
Ko, C.H.5
Wang, L.M.6
Chen, Y.C.7
-
208
-
-
68349110545
-
Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids
-
Phromnoi, K.; Yodkeeree, S.; Anuchapreeda, S.; Limtrakul, P. Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids. Acta Pharmacol. Sin. 2009, 30, 1169–1176.
-
(2009)
Acta Pharmacol. Sin
, vol.30
, pp. 1169-1176
-
-
Phromnoi, K.1
Yodkeeree, S.2
Anuchapreeda, S.3
Limtrakul, P.4
-
209
-
-
33745945847
-
Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3)
-
Vijayababu, M.R.; Arunkumar, A.; Kanagaraj, P.; Venkataraman, P.; Krishnamoorthy, G.; Arunakaran, J. Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3). Mol. Cell. Biochem. 2006, 287, 109–116.
-
(2006)
Mol. Cell. Biochem
, vol.287
, pp. 109-116
-
-
Vijayababu, M.R.1
Arunkumar, A.2
Kanagaraj, P.3
Venkataraman, P.4
Krishnamoorthy, G.5
Arunakaran, J.6
-
210
-
-
79952211178
-
Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3)
-
Senthilkumar, K.; Arunkumar, R.; Elumalai, P.; Sharmila, G.; Gunadharini, D.N.; Banudevi, S.; Krishnamoorthy, G.; Benson, C.S.; Arunakaran, J. Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3). Cell Biochem. Funct. 2011, 29, 87–95.
-
(2011)
Cell Biochem. Funct
, vol.29
, pp. 87-95
-
-
Senthilkumar, K.1
Arunkumar, R.2
Elumalai, P.3
Sharmila, G.4
Gunadharini, D.N.5
Banudevi, S.6
Krishnamoorthy, G.7
Benson, C.S.8
Arunakaran, J.9
-
211
-
-
70449519966
-
Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation
-
C
-
Chiu, W.T.; Shen, S.C.; Chow, J.M.; Lin, C.W.; Shia, L.T.; Chen, Y.C. Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. Neurobiol. Dis. 2010, 37, 118–129.
-
(2010)
Neurobiol. Dis
, vol.37
, pp. 118-129
-
-
Hiu, W.T.1
Shen, S.C.2
Chow, J.M.3
Lin, C.W.4
Shia, L.T.5
Chen, Y.C.6
-
212
-
-
64049102516
-
The flavonols quercetin, kaempferol, and myricetin inhibit hepatocyte growth factor-induced medulloblastoma cell migration
-
Labbe, D.; Provencal, M.; Lamy, S.; Boivin, D.; Gingras, D.; Beliveau, R. The flavonols quercetin, kaempferol, and myricetin inhibit hepatocyte growth factor-induced medulloblastoma cell migration. J. Nutr. 2009, 139, 646–652.
-
(2009)
J. Nutr
, vol.139
, pp. 646-652
-
-
Labbe, D.1
Provencal, M.2
Lamy, S.3
Boivin, D.4
Gingras, D.5
Beliveau, R.6
-
213
-
-
81155159628
-
Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells
-
Lin, Y.S.; Tsai, P.H.; Kandaswami, C.C.; Cheng, C.H.; Ke, F.C.; Lee, P.P.; Hwang, J.J.; Lee, M.T. Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells. Cancer Sci. 2011, 102, 1829–1839.
-
(2011)
Cancer Sci
, vol.102
, pp. 1829-1839
-
-
Lin, Y.S.1
Tsai, P.H.2
Kandaswami, C.C.3
Cheng, C.H.4
Ke, F.C.5
Lee, P.P.6
Hwang, J.J.7
Lee, M.T.8
-
214
-
-
60749131906
-
Effects of quercetin on proliferation, apoptosis, adhesion and migration, and invasion of HeLa cells
-
Zhang, W.; Zhang, F. Effects of quercetin on proliferation, apoptosis, adhesion and migration, and invasion of HeLa cells. Eur. J. Gynaecol. Oncol. 2009, 30, 60–64.
-
(2009)
Eur. J. Gynaecol. Oncol
, vol.30
, pp. 60-64
-
-
Zhang, W.1
Zhang, F.2
-
215
-
-
0742286824
-
Quercetin inhibits the invasion of murine melanoma B16-BL6 cells by decreasing pro-MMP-9 via the PKC pathway. Cancer Chemother
-
Zhang, X.M.; Huang, S.P.; Xu, Q. Quercetin inhibits the invasion of murine melanoma B16-BL6 cells by decreasing pro-MMP-9 via the PKC pathway. Cancer Chemother. Pharmacol. 2004, 53, 82–88.
-
(2004)
Pharmacol
, vol.53
, pp. 82-88
-
-
Zhang, X.M.1
Huang, S.P.2
Xu, Q.3
-
216
-
-
33746915646
-
Suppression of tumor growth and invasion in 9,10 dimethyl benz(A) anthracene induced mammary carcinoma by the plant bioflavonoid quercetin
-
Devipriya, S.; Ganapathy, V.; Shyamaladevi, C.S. Suppression of tumor growth and invasion in 9,10 dimethyl benz(a) anthracene induced mammary carcinoma by the plant bioflavonoid quercetin. Chem. Biol. Interact. 2006, 162, 106–113.
-
(2006)
Chem. Biol. Interact
, vol.162
, pp. 106-113
-
-
Devipriya, S.1
Ganapathy, V.2
Shyamaladevi, C.S.3
-
217
-
-
84954357211
-
Didymin reverses phthalate ester-associated breast cancer aggravation in the breast cancer tumor microenvironment
-
Hsu, Y.L.; Hsieh, C.J.; Tsai, E.M.; Hung, J.Y.; Chang, W.A.; Hou, M.F.; Kuo, P.L. Didymin reverses phthalate ester-associated breast cancer aggravation in the breast cancer tumor microenvironment. Oncol. Lett. 2016, 11, 1035–1042.
-
(2016)
Oncol. Lett
, vol.11
, pp. 1035-1042
-
-
Hsu, Y.L.1
Hsieh, C.J.2
Tsai, E.M.3
Hung, J.Y.4
Chang, W.A.5
Hou, M.F.6
Kuo, P.L.7
-
218
-
-
9744222928
-
Potential synergy of phytochemicals in cancer prevention: Mechanism of action
-
Liu, R.H. Potential synergy of phytochemicals in cancer prevention: Mechanism of action. J. Nutr. 2004, 134, 3479S–3485S.
-
(2004)
J. Nutr
, vol.134
, pp. 3479S-3485S
-
-
Liu, R.H.1
-
219
-
-
0029781370
-
Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices
-
So, F.V.; Guthrie, N.; Chambers, A.F.; Moussa, M.; Carroll, K.K. Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutr. Cancer Int. J. 1996, 26, 167–181.
-
(1996)
Nutr. Cancer Int. J
, vol.26
, pp. 167-181
-
-
So, F.V.1
Guthrie, N.2
Chambers, A.F.3
Moussa, M.4
Carroll, K.K.5
-
220
-
-
0031688513
-
Inhibition of mammary cancer by Citrus flavonoids
-
Guthrie, N.; Carroll, K.K. Inhibition of mammary cancer by Citrus flavonoids. Flavonoids Cell Funct. 1998, 439, 227–236.
-
(1998)
Flavonoids Cell Funct
, vol.439
, pp. 227-236
-
-
Guthrie, N.1
Carroll, K.K.2
-
221
-
-
0033917711
-
Inhibition of azoxymethane-induced colon cancer by orange juice
-
Miyagi, Y.; Om, A.S.; Chee, K.M.; Bennink, M.R. Inhibition of azoxymethane-induced colon cancer by orange juice. Nutr. Cancer Int. J. 2000, 36, 224–229.
-
(2000)
Nutr. Cancer Int. J
, vol.36
, pp. 224-229
-
-
Miyagi, Y.1
Om, A.S.2
Chee, K.M.3
Bennink, M.R.4
-
222
-
-
0033862109
-
Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin
-
Tanaka, T.; Kohno, H.; Murakami, M.; Shimada, R.; Kagami, S.; Sumida, T.; Azuma, Y.; Ogawa, H. Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin. Int. J. Cancer 2000, 88, 146–150.
-
(2000)
Int. J. Cancer
, vol.88
, pp. 146-150
-
-
Tanaka, T.1
Kohno, H.2
Murakami, M.3
Shimada, R.4
Kagami, S.5
Sumida, T.6
Azuma, Y.7
Ogawa, H.8
-
223
-
-
0035965943
-
Inhibitory effect of mandarin juice rich in beta-cryptoxanthin and hesperidin on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary tumorigenesis in mice
-
Kohno, H.; Taima, M.; Sumida, T.; Azuma, Y.; Ogawa, H.; Tanaka, T. Inhibitory effect of mandarin juice rich in beta-cryptoxanthin and hesperidin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary tumorigenesis in mice. Cancer Lett. 2001, 174, 141–150.
-
(2001)
Cancer Lett
, vol.174
, pp. 141-150
-
-
Kohno, H.1
Taima, M.2
Sumida, T.3
Azuma, Y.4
Ogawa, H.5
Tanaka, T.6
-
224
-
-
84855521755
-
Cancer chemoprevention by Citrus pulp and juices containing high amounts of beta-cryptoxanthin and hesperidin
-
Tanaka, T.; Tanaka, T.; Tanaka, M.; Kuno, T. Cancer chemoprevention by Citrus pulp and juices containing high amounts of beta-cryptoxanthin and hesperidin. J. Biomed. Biotechnol. 2012, 2012, 516981.
-
(2012)
J. Biomed. Biotechnol
, vol.2012
-
-
Tanaka, T.1
Tanaka, T.2
Tanaka, M.3
Kuno, T.4
-
225
-
-
0000389965
-
Prevention of colonic preneoplastic lesions by the β-cryptoxanthin and hesperidin rich powder prepared from Citrus unshiu marc. Juice in male f344 rats
-
Kohno, H.; Maeda, M.; Honjo, S.; Murakami, M.; Shimada, R.; Masuda, S.; Sumida, T.; Azuma, Y.; Ogawa, H.; Tanaka, T. Prevention of colonic preneoplastic lesions by the β-cryptoxanthin and hesperidin rich powder prepared from Citrus unshiu marc. Juice in male f344 rats. J. Toxicol. Pathol. 1999, 12, 209–215.
-
(1999)
J. Toxicol. Pathol
, vol.12
, pp. 209-215
-
-
Kohno, H.1
Maeda, M.2
Honjo, S.3
Murakami, M.4
Shimada, R.5
Masuda, S.6
Sumida, T.7
Azuma, Y.8
Ogawa, H.9
Tanaka, T.10
-
226
-
-
84942989630
-
Flavonoid fraction of Citrus reticulata juice reduces proliferation and migration of anaplastic thyroid carcinoma cells
-
Celano, M.; Maggisano, V.; De Rose, R.F.; Bulotta, S.; Maiuolo, J.; Navarra, M.; Russo, D. Flavonoid fraction of Citrus reticulata juice reduces proliferation and migration of anaplastic thyroid carcinoma cells. Nutr. Cancer Int. J. 2015, 67, 1183–1190.
-
(2015)
Nutr. Cancer Int. J
, vol.67
, pp. 1183-1190
-
-
Celano, M.1
Maggisano, V.2
De Rose, R.F.3
Bulotta, S.4
Maiuolo, J.5
Navarra, M.6
Russo, D.7
-
227
-
-
84858066391
-
Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon Citrus extract
-
Alshatwi, A.A.; Shafi, G.; Hasan, T.N.; Al-Hazzani, A.A.; Alsaif, M.A.; Alfawaz, M.A.; Lei, K.Y.; Munshi, A. Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon Citrus extract. Asian Pac. J. Cancer Prev. 2011, 12, 1555–1559.
-
(2011)
Asian Pac. J. Cancer Prev
, vol.12
, pp. 1555-1559
-
-
Alshatwi, A.A.1
Shafi, G.2
Hasan, T.N.3
Al-Hazzani, A.A.4
Alsaif, M.A.5
Alfawaz, M.A.6
Lei, K.Y.7
Munshi, A.8
-
228
-
-
84862777076
-
Evaluation of chemopreventive and cytotoxic effect of lemon seed extracts on human breast cancer (MCF-7) cells. Food
-
Kim, J.; Jayaprakasha, G.K.; Uckoo, R.M.; Patil, B.S. Evaluation of chemopreventive and cytotoxic effect of lemon seed extracts on human breast cancer (MCF-7) cells. Food Chem. Toxicol. 2012, 50, 423–430.
-
(2012)
Chem. Toxicol
, vol.50
, pp. 423-430
-
-
Kim, J.1
Jayaprakasha, G.K.2
Uckoo, R.M.3
Patil, B.S.4
-
229
-
-
84876183786
-
Mechanisms underlying the anti-tumoral effects of Citrus bergamia juice
-
Delle Monache, S.; Sanita, P.; Trapasso, E.; Ursino, M.R.; Dugo, P.; Russo, M.; Ferlazzo, N.; Calapai, G.; Angelucci, A.; Navarra, M. Mechanisms underlying the anti-tumoral effects of Citrus bergamia juice. PLoS ONE 2013, 8, e61484.
-
(2013)
PLoS ONE
, vol.8
-
-
Delle Monache, S.1
Sanita, P.2
Trapasso, E.3
Ursino, M.R.4
Dugo, P.5
Russo, M.6
Ferlazzo, N.7
Calapai, G.8
Angelucci, A.9
Navarra, M.10
-
230
-
-
84954286208
-
NF-κB mediates the antiproliferative and proapoptotic effects of bergamot juice in HepG2 cells
-
Ferlazzo, N.; Cirmi, S.; Russo, M.; Trapasso, E.; Ursino, M.R.; Lombardo, G.E.; Gangemi, S.; Calapai, G.; Navarra, M. NF-κB mediates the antiproliferative and proapoptotic effects of bergamot juice in HepG2 cells. Life Sci. 2016, 146, 81–91.
-
(2016)
Life Sci
, vol.146
, pp. 81-91
-
-
Ferlazzo, N.1
Cirmi, S.2
Russo, M.3
Trapasso, E.4
Ursino, M.R.5
Lombardo, G.E.6
Gangemi, S.7
Calapai, G.8
Navarra, M.9
-
231
-
-
84897084127
-
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models
-
Navarra, M.; Ursino, M.R.; Ferlazzo, N.; Russo, M.; Schumacher, U.; Valentiner, U. Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models. Fitoterapia 2014, 95, 83–92.
-
(2014)
Fitoterapia
, vol.95
, pp. 83-92
-
-
Navarra, M.1
Ursino, M.R.2
Ferlazzo, N.3
Russo, M.4
Schumacher, U.5
Valentiner, U.6
-
232
-
-
84907437144
-
Bergamot juice extract inhibits proliferation by inducing apoptosis in human colon cancer cells
-
Visalli, G.; Ferlazzo, N.; Cirmi, S.; Campiglia, P.; Gangemi, S.; Di Pietro, A.; Calapai, G.; Navarra, M. Bergamot juice extract inhibits proliferation by inducing apoptosis in human colon cancer cells. Anticancer Agents Med. Chem. 2014, 14, 1402–1413.
-
(2014)
Anticancer Agents Med. Chem
, vol.14
, pp. 1402-1413
-
-
Visalli, G.1
Ferlazzo, N.2
Cirmi, S.3
Campiglia, P.4
Gangemi, S.5
Di Pietro, A.6
Calapai, G.7
Navarra, M.8
-
233
-
-
0035901090
-
Inflammation and cancer: Back to virchow?
-
Balkwill, F.; Mantovani, A. Inflammation and cancer: Back to virchow? Lancet 2001, 357, 539–545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
234
-
-
84899071584
-
Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: A new therapeutic approach to disease progression and recurrence
-
Crawford, S. Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: A new therapeutic approach to disease progression and recurrence. Ther. Adv. Med. Oncol. 2014, 6, 52–68.
-
(2014)
Ther. Adv. Med. Oncol
, vol.6
, pp. 52-68
-
-
Crawford, S.1
-
235
-
-
84938150134
-
Flavonoid fraction of orange and bergamot juices protect human lung epithelial cells from hydrogen peroxide-induced oxidative stress
-
Ferlazzo, N.; Visalli, G.; Smeriglio, A.; Cirmi, S.; Lombardo, G.E.; Campiglia, P.; di Pietro, A.; Navarra, M. Flavonoid fraction of orange and bergamot juices protect human lung epithelial cells from hydrogen peroxide-induced oxidative stress. Evid. Based Complement. Altern. Med. 2015, 2015, 957031.
-
(2015)
Evid. Based Complement. Altern. Med
, vol.2015
-
-
Ferlazzo, N.1
Visalli, G.2
Smeriglio, A.3
Cirmi, S.4
Lombardo, G.E.5
Campiglia, P.6
Di Pietro, A.7
Navarra, M.8
-
236
-
-
84962257846
-
Natural iron chelators: Protective role in A549 cells of flavonoids-rich extracts of Citrus juices in Fe3+-induced oxidative stress
-
Ferlazzo, N.; Visalli, G.; Cirmi, S.; Lombardo, G.E.; Lagana, P.; di Pietro, A.; Navarra, M. Natural iron chelators: Protective role in A549 cells of flavonoids-rich extracts of Citrus juices in Fe3+-induced oxidative stress. Environ. Toxicol. Pharmacol. 2016, 43, 248–256.
-
(2016)
Environ. Toxicol. Pharmacol
, vol.43
, pp. 248-256
-
-
Ferlazzo, N.1
Visalli, G.2
Cirmi, S.3
Lombardo, G.E.4
Lagana, P.5
Di Pietro, A.6
Navarra, M.7
-
237
-
-
84907426298
-
Flavonoid fraction of bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-kB inhibition in THP-1 monocytes
-
Risitano, R.; Currò, M.; Cirmi, S.; Ferlazzo, N.; Campiglia, P.; Caccamo, D.; Ientile, R.; Navarra, M. Flavonoid fraction of bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-kB inhibition in THP-1 monocytes. PLoS ONE 2014, 9, e107431.
-
(2014)
PLoS ONE
, vol.9
-
-
Risitano, R.1
Currò, M.2
Cirmi, S.3
Ferlazzo, N.4
Campiglia, P.5
Caccamo, D.6
Ientile, R.7
Navarra, M.8
-
238
-
-
84957818799
-
Citrus bergamia juice extract attenuates beta-amyloid-induced pro-inflammatory activation of THP-1 cells through MAPK and AP-1 pathways
-
Currò, M.; Risitano, R.; Ferlazzo, N.; Cirmi, S.; Gangemi, C.; Caccamo, D.; Ientile, R.; Navarra, M. Citrus bergamia juice extract attenuates beta-amyloid-induced pro-inflammatory activation of THP-1 cells through MAPK and AP-1 pathways. Sci. Rep. 2016, 6, 20809.
-
(2016)
Sci. Rep
, vol.6
, pp. 20809
-
-
Currò, M.1
Risitano, R.2
Ferlazzo, N.3
Cirmi, S.4
Gangemi, C.5
Caccamo, D.6
Ientile, R.7
Navarra, M.8
-
239
-
-
84914166696
-
The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease
-
Impellizzeri, D.; Bruschetta, G.; di Paola, R.; Ahmad, A.; Campolo, M.; Cuzzocrea, S.; Esposito, E.; Navarra, M. The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease. Clin. Nutr. 2015, 34, 1146–1154.
-
(2015)
Clin. Nutr
, vol.34
, pp. 1146-1154
-
-
Impellizzeri, D.1
Bruschetta, G.2
Di Paola, R.3
Ahmad, A.4
Campolo, M.5
Cuzzocrea, S.6
Esposito, E.7
Navarra, M.8
-
240
-
-
84995392463
-
Anti-inflammatory and antioxidant effects of flavonoid-rich fraction of bergamot juice (BJe) in a mouse model of intestinal ischemia/reperfusion injury
-
Impellizzeri, D.; Cordaro, M.; Campolo, M.; Gugliandolo, E.; Esposito, E.; Benedetto, F.; Cuzzocrea, S.; Navarra, M. Anti-inflammatory and antioxidant effects of flavonoid-rich fraction of bergamot juice (BJe) in a mouse model of intestinal ischemia/reperfusion injury. FASEB J. 2016, 30 (Suppl. 1), 720–725.
-
(2016)
FASEB J
, vol.30
, pp. 720-725
-
-
Impellizzeri, D.1
Cordaro, M.2
Campolo, M.3
Gugliandolo, E.4
Esposito, E.5
Benedetto, F.6
Cuzzocrea, S.7
Navarra, M.8
-
241
-
-
84938053061
-
In vitro effect of bergamot (Citrus bergamia) juice against cagA-positive and-negative clinical isolates of helicobacter pylori
-
[CrossRef]
-
Filocamo, A.; Bisignano, C.; Ferlazzo, N.; Cirmi, S.; Mandalari, G.; Navarra, M. In vitro effect of bergamot (Citrus bergamia) juice against cagA-positive and-negative clinical isolates of helicobacter pylori. BMC Complement. Altern. Med. 2015, 15. [CrossRef]
-
(2015)
BMC Complement. Altern. Med
, vol.15
-
-
Filocamo, A.1
Bisignano, C.2
Ferlazzo, N.3
Cirmi, S.4
Mandalari, G.5
Navarra, M.6
-
242
-
-
84985996196
-
Anti-infective potential of Citrus bergamia risso et poiteau (Bergamot) derivatives: A systematic review
-
[CrossRef]
-
Cirmi, S.; Bisignano, C.; Mandalari, G.; Navarra, M. Anti-infective potential of Citrus bergamia risso et poiteau (bergamot) derivatives: A systematic review. Phytother. Res. 2016. [CrossRef]
-
(2016)
Phytother. Res
-
-
Cirmi, S.1
Bisignano, C.2
Mandalari, G.3
Navarra, M.4
-
243
-
-
84927553388
-
Role of natural antioxidants and potential use of bergamot in treating rheumatoid arthritis
-
Marino, A.; Paterniti, I.; Cordaro, M.; Morabito, R.; Campolo, M.; Navarra, M.; Esposito, E.; Cuzzocrea, S. Role of natural antioxidants and potential use of bergamot in treating rheumatoid arthritis. PharmaNutrition 2015, 3, 53–59.
-
(2015)
Pharmanutrition
, vol.3
, pp. 53-59
-
-
Marino, A.1
Paterniti, I.2
Cordaro, M.3
Morabito, R.4
Campolo, M.5
Navarra, M.6
Esposito, E.7
Cuzzocrea, S.8
-
244
-
-
0029883874
-
Isolation of anti-leukemia compounds from Citrus reticulata
-
Mak, N.K.; WongLeung, Y.L.; Chan, S.C.; Wen, J.M.; Leung, K.N.; Fung, M.C. Isolation of anti-leukemia compounds from Citrus reticulata. Life Sci. 1996, 58, 1269–1276.
-
(1996)
Life Sci
, vol.58
, pp. 1269-1276
-
-
Mak, N.K.1
Wongleung, Y.L.2
Chan, S.C.3
Wen, J.M.4
Leung, K.N.5
Fung, M.C.6
-
245
-
-
14944372950
-
Citrus reticulata blanco induces apoptosis in human gastric cancer cells SNU-668
-
Kim, M.J.; Park, H.J.; Hong, M.S.; Park, H.J.; Kim, M.S.; Leem, K.H.; Kim, J.B.; Kim, Y.J.; Kim, H.K. Citrus reticulata blanco induces apoptosis in human gastric cancer cells SNU-668. Nutr. Cancer 2005, 51, 78–82.
-
(2005)
Nutr. Cancer
, vol.51
, pp. 78-82
-
-
Kim, M.J.1
Park, H.J.2
Hong, M.S.3
Park, H.J.4
Kim, M.S.5
Leem, K.H.6
Kim, J.B.7
Kim, Y.J.8
Kim, H.K.9
-
246
-
-
84865341668
-
Induction of the cell cycle arrest and apoptosis by flavonoids isolated from korean Citrus aurantium L. In non-small-cell lung cancer cells
-
Park, K.I.; Park, H.S.; Nagappan, A.; Hong, G.E.; Lee, D.H.; Kang, S.R.; Kim, J.A.; Zhang, J.; Kim, E.H.; Lee, W.S.; et al. Induction of the cell cycle arrest and apoptosis by flavonoids isolated from korean Citrus aurantium L. In non-small-cell lung cancer cells. Food Chem. 2012, 135, 2728–2735.
-
(2012)
Food Chem
, vol.135
, pp. 2728-2735
-
-
Park, K.I.1
Park, H.S.2
Nagappan, A.3
Hong, G.E.4
Lee, D.H.5
Kang, S.R.6
Kim, J.A.7
Zhang, J.8
Kim, E.H.9
Lee, W.S.10
-
247
-
-
84861790533
-
Citrus aurantium L. Exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of AKT
-
Han, M.H.; Lee, W.S.; Lu, J.N.; Kim, G.; Jung, J.M.; Ryu, C.H.; Kim, G.Y.; Hwang, H.J.; Kwon, T.K.; Choi, Y.H. Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of AKT. Int. J. Oncol. 2012, 40, 2090–2096.
-
(2012)
Int. J. Oncol
, vol.40
, pp. 2090-2096
-
-
Han, M.H.1
Lee, W.S.2
Lu, J.N.3
Kim, G.4
Jung, J.M.5
Ryu, C.H.6
Kim, G.Y.7
Hwang, H.J.8
Kwon, T.K.9
Choi, Y.H.10
-
248
-
-
84905112496
-
Combination of ethanolic extract of Citrus aurantifolia peels with doxorubicin modulate cell cycle and increase apoptosis induction on MCF-7 cells. Iran
-
Adina, A.B.; Goenadi, F.A.; Handoko, F.F.; Nawangsari, D.A.; Hermawan, A.; Jenie, R.I.; Meiyanto, E. Combination of ethanolic extract of Citrus aurantifolia peels with doxorubicin modulate cell cycle and increase apoptosis induction on MCF-7 cells. Iran. J. Pharm. Res. 2014, 13, 919–926.
-
(2014)
J. Pharm. Res
, vol.13
, pp. 919-926
-
-
Adina, A.B.1
Goenadi, F.A.2
Handoko, F.F.3
Nawangsari, D.A.4
Hermawan, A.5
Jenie, R.I.6
Meiyanto, E.7
-
249
-
-
84937415675
-
Pure total flavonoids from Citrus paradisi Macfadyen act synergistically with arsenic trioxide in inducing apoptosis of kasumi-1 leukemia cells in vitro
-
Wang, B.; Lin, S.Y.; Shen, Y.Y.; Wu, L.Q.; Chen, Z.Z.; Li, J.; Chen, Z.; Qian, W.B.; Jiang, J.P. Pure total flavonoids from Citrus paradisi Macfadyen act synergistically with arsenic trioxide in inducing apoptosis of kasumi-1 leukemia cells in vitro. J. Zhejiang Univ. Sci. B 2015, 16, 580–585.
-
(2015)
J. Zhejiang Univ. Sci. B
, vol.16
, pp. 580-585
-
-
Wang, B.1
Lin, S.Y.2
Shen, Y.Y.3
Wu, L.Q.4
Chen, Z.Z.5
Li, J.6
Chen, Z.7
Qian, W.B.8
Jiang, J.P.9
-
250
-
-
84887017025
-
Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells
-
Celia, C.; Trapasso, E.; Locatelli, M.; Navarra, M.; Ventura, C.A.; Wolfram, J.; Carafa, M.; Morittu, V.M.; Britti, D.; di Marzio, L.; et al. Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. Colloids Surf. B Biointerfaces 2013, 112, 548–553.
-
(2013)
Colloids Surf. B Biointerfaces
, vol.112
, pp. 548-553
-
-
Celia, C.1
Trapasso, E.2
Locatelli, M.3
Navarra, M.4
Ventura, C.A.5
Wolfram, J.6
Carafa, M.7
Morittu, V.M.8
Britti, D.9
Di Marzio, L.10
-
251
-
-
84927529417
-
Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth
-
Navarra, M.; Ferlazzo, N.; Cirmi, S.; Trapasso, E.; Bramanti, P.; Lombardo, G.E.; Minciullo, P.L.; Calapai, G.; Gangemi, S. Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth. J. Pharm. Pharmacol. 2015, 67, 1042–1053.
-
(2015)
J. Pharm. Pharmacol
, vol.67
, pp. 1042-1053
-
-
Navarra, M.1
Ferlazzo, N.2
Cirmi, S.3
Trapasso, E.4
Bramanti, P.5
Lombardo, G.E.6
Minciullo, P.L.7
Calapai, G.8
Gangemi, S.9
-
252
-
-
0033988920
-
Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China
-
Yuan, J.M.; Wang, X.L.; Xiang, Y.B.; Gao, Y.T.; Ross, R.K.; Yu, M.C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int. J. Cancer 2000, 85, 358–363.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 358-363
-
-
Yuan, J.M.1
Wang, X.L.2
Xiang, Y.B.3
Gao, Y.T.4
Ross, R.K.5
Yu, M.C.6
-
253
-
-
0034662294
-
Food groups and risk of squamous cell esophageal cancer in northern Italy
-
Bosetti, C.; la Vecchia, C.; Talamini, R.; Simonato, L.; Zambon, P.; Negri, E.; Trichopoulos, D.; Lagiou, P.; Bardini, R.; Franceschi, S. Food groups and risk of squamous cell esophageal cancer in northern Italy. Int. J. Cancer 2000, 87, 289–294.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 289-294
-
-
Bosetti, C.1
La Vecchia, C.2
Talamini, R.3
Simonato, L.4
Zambon, P.5
Negri, E.6
Trichopoulos, D.7
Lagiou, P.8
Bardini, R.9
Franceschi, S.10
-
254
-
-
79957650071
-
Vegetables and fruits consumption and risk of esophageal and gastric cancer subtypes in the Netherlands cohort study
-
Steevens, J.; Schouten, L.J.; Goldbohm, R.A.; van den Brandt, P.A. Vegetables and fruits consumption and risk of esophageal and gastric cancer subtypes in the Netherlands cohort study. Int. J. Cancer 2011, 129, 2681–2693.
-
(2011)
Int. J. Cancer
, vol.129
, pp. 2681-2693
-
-
Steevens, J.1
Schouten, L.J.2
Goldbohm, R.A.3
Van Den Brandt, P.A.4
-
255
-
-
0032957017
-
Food groups, oils and butter, and cancer of the oral cavity and pharynx
-
Franceschi, S.; Favero, A.; Conti, E.; Talamini, R.; Volpe, R.; Negri, E.; Barzan, L.; la Vecchia, C. Food groups, oils and butter, and cancer of the oral cavity and pharynx. Br. J. Cancer 1999, 80, 614–620.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 614-620
-
-
Franceschi, S.1
Favero, A.2
Conti, E.3
Talamini, R.4
Volpe, R.5
Negri, E.6
Barzan, L.7
La Vecchia, C.8
-
256
-
-
0037143103
-
Food groups and laryngeal cancer risk: A case-control study from Italy and Switzerland
-
Bosetti, C.; la Vecchia, C.; Talamini, R.; Negri, E.; Levi, F.; dal Maso, L.; Franceschi, S. Food groups and laryngeal cancer risk: A case-control study from Italy and Switzerland. Int. J. Cancer 2002, 100, 355–360.
-
(2002)
Int. J. Cancer
, vol.100
, pp. 355-360
-
-
Bosetti, C.1
La Vecchia, C.2
Talamini, R.3
Negri, E.4
Levi, F.5
Dal Maso, L.6
Franceschi, S.7
-
257
-
-
33748792031
-
Prospective study of fruits and vegetables and risk of oral premalignant lesions in men
-
Maserejian, N.N.; Giovannucci, E.; Rosner, B.; Zavras, A.; Joshipura, K. Prospective study of fruits and vegetables and risk of oral premalignant lesions in men. Am. J. Epidemiol. 2006, 164, 556–566.
-
(2006)
Am. J. Epidemiol
, vol.164
, pp. 556-566
-
-
Maserejian, N.N.1
Giovannucci, E.2
Rosner, B.3
Zavras, A.4
Joshipura, K.5
-
258
-
-
33745161859
-
Association between fruit and vegetable consumption and oral cancer: A meta-analysis of observational studies
-
Pavia, M.; Pileggi, C.; Nobile, C.G.A.; Angelillo, I.F. Association between fruit and vegetable consumption and oral cancer: A meta-analysis of observational studies. Am. J. Clin. Nutr. 2006, 83, 1126–1134.
-
(2006)
Am. J. Clin. Nutr
, vol.83
, pp. 1126-1134
-
-
Pavia, M.1
Pileggi, C.2
Nobile, C.G.A.3
Angelillo, I.F.4
-
259
-
-
70349237438
-
The role of diet and other environmental factors in the causation of gastric cancer in Iran-a population based study
-
Pourfarzi, F.; Whelan, A.; Kaldor, J.; Malekzadeh, R. The role of diet and other environmental factors in the causation of gastric cancer in Iran-a population based study. Int. J. Cancer 2009, 125, 1953–1960.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 1953-1960
-
-
Pourfarzi, F.1
Whelan, A.2
Kaldor, J.3
Malekzadeh, R.4
-
260
-
-
77950691556
-
Citrus fruit and cancer risk in a network of case-control studies
-
Foschi, R.; Pelucchi, C.; dal Maso, L.; Rossi, M.; Levi, F.; Talamini, R.; Bosetti, C.; Negri, E.; Serraino, D.; Giacosa, A.; et al. Citrus fruit and cancer risk in a network of case-control studies. Cancer Causes Control 2010, 21, 237–242.
-
(2010)
Cancer Causes Control
, vol.21
, pp. 237-242
-
-
Foschi, R.1
Pelucchi, C.2
Dal Maso, L.3
Rossi, M.4
Levi, F.5
Talamini, R.6
Bosetti, C.7
Negri, E.8
Serraino, D.9
Giacosa, A.10
-
261
-
-
84867886475
-
Fruit and vegetable intake and the risk of gastric adenocarcinoma: A reanalysis of the european prospective investigation into cancer and nutrition (epic-eurgast) study after a longer follow-up
-
Gonzalez, C.A.; Lujan-Barroso, L.; Bueno-de-Mesquita, H.B.; Jenab, M.; Duell, E.J.; Agudo, A.; Tjonneland, A.; Boutron-Ruault, M.C.; Clavel-Chapelon, F.; Touillaud, M.; et al. Fruit and vegetable intake and the risk of gastric adenocarcinoma: A reanalysis of the european prospective investigation into cancer and nutrition (epic-eurgast) study after a longer follow-up. Int. J. Cancer 2012, 131, 2910–2919.
-
(2012)
Int. J. Cancer
, vol.131
, pp. 2910-2919
-
-
Gonzalez, C.A.1
Lujan-Barroso, L.2
Bueno-De-Mesquita, H.B.3
Jenab, M.4
Duell, E.J.5
Agudo, A.6
Tjonneland, A.7
Boutron-Ruault, M.C.8
Clavel-Chapelon, F.9
Touillaud, M.10
-
262
-
-
0030741374
-
Food groups and risk of colorectal cancer in Italy
-
Franceschi, S.; Favero, A.; la Vecchia, C.; Negri, E.; Conti, E.; Montella, M.; Giacosa, A.; Nanni, O.; Decarli, A. Food groups and risk of colorectal cancer in Italy. Int. J. Cancer 1997, 72, 56–61.
-
(1997)
Int. J. Cancer
, vol.72
, pp. 56-61
-
-
Franceschi, S.1
Favero, A.2
La Vecchia, C.3
Negri, E.4
Conti, E.5
Montella, M.6
Giacosa, A.7
Nanni, O.8
Decarli, A.9
-
263
-
-
0033026213
-
Food groups and colorectal cancer risk
-
Levi, F.; Pasche, C.; la Vecchia, C.; Lucchini, F.; Franceschi, S. Food groups and colorectal cancer risk. Br. J. Cancer 1999, 79, 1283–1287.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1283-1287
-
-
Levi, F.1
Pasche, C.2
La Vecchia, C.3
Lucchini, F.4
Franceschi, S.5
-
264
-
-
0037882042
-
Ntake of fruits, vegetables and selected micronutrients in relation to the risk of breast cancer
-
Malin, A.S.; Qi, D.; Shu, X.O.; Gao, Y.T.; Friedmann, J.M.; Jin, F.; Zheng, W. Intake of fruits, vegetables and selected micronutrients in relation to the risk of breast cancer. Int. J. Cancer 2003, 105, 413–418.
-
(2003)
Int. J. Cancer
, vol.105
, pp. 413-418
-
-
Malin, A.S.1
Qi, D.2
Shu, X.O.3
Gao, Y.T.4
Friedmann, J.M.5
Jin, F.6
Zheng, W.7
-
265
-
-
77957143924
-
Hormonal and metabolic modulation through nutrition: Towards a primary prevention of breast cancer
-
Ronco, A.L.; de Stefani, E.; Stoll, M. Hormonal and metabolic modulation through nutrition: Towards a primary prevention of breast cancer. Breast 2010, 19, 322–332.
-
(2010)
Breast
, vol.19
, pp. 322-332
-
-
Ronco, A.L.1
De Stefani, E.2
Stoll, M.3
-
266
-
-
82955161686
-
Fruit and vegetable consumption is inversely associated with having pancreatic cancer
-
Jansen, R.J.; Robinson, D.P.; Stolzenberg-Solomon, R.Z.; Bamlet, W.R.; de Andrade, M.; Oberg, A.L.; Hammer, T.J.; Rabe, K.G.; Anderson, K.E.; Olson, J.E.; et al. Fruit and vegetable consumption is inversely associated with having pancreatic cancer. Cancer Causes Control 2011, 22, 1613–1625.
-
(2011)
Cancer Causes Control
, vol.22
, pp. 1613-1625
-
-
Jansen, R.J.1
Robinson, D.P.2
Stolzenberg-Solomon, R.Z.3
Bamlet, W.R.4
De Andrade, M.5
Oberg, A.L.6
Hammer, T.J.7
Rabe, K.G.8
Anderson, K.E.9
Olson, J.E.10
-
267
-
-
27744521872
-
Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area. Cancer Epidemiol. Biomark
-
Chan, J.M.; Wang, F.; Holly, E.A. Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area. Cancer Epidemiol. Biomark. Prev. 2005, 14, 2093–2097.
-
(2005)
Prev
, vol.14
, pp. 2093-2097
-
-
Chan, J.M.1
Wang, F.2
Holly, E.A.3
-
268
-
-
11844299074
-
Do dietary lycopene and other carotenoids protect against prostate cancer
-
Jian, L.; Du, C.J.; Lee, A.H.; Binns, C.W. Do dietary lycopene and other carotenoids protect against prostate cancer? Int. J. Cancer 2005, 113, 1010–1014.
-
(2005)
Int. J. Cancer
, vol.113
, pp. 1010-1014
-
-
Jian, L.1
Du, C.J.2
Lee, A.H.3
Binns, C.W.4
-
269
-
-
53349176567
-
A protective effect of the mediterranean diet for cutaneous melanoma
-
Fortes, C.; Mastroeni, S.; Melchi, F.; Pilla, M.A.; Antonelli, G.; Camaioni, D.; Alotto, M.; Pasquini, P. A protective effect of the mediterranean diet for cutaneous melanoma. Int. J. Epidemiol. 2008, 37, 1018–1029.
-
(2008)
Int. J. Epidemiol
, vol.37
, pp. 1018-1029
-
-
Fortes, C.1
Mastroeni, S.2
Melchi, F.3
Pilla, M.A.4
Antonelli, G.5
Camaioni, D.6
Alotto, M.7
Pasquini, P.8
-
270
-
-
77957008710
-
Citrus consumption and cancer incidence: The Ohsaki cohort study
-
Li, W.Q.; Kuriyama, S.; Li, Q.; Nagai, M.; Hozawa, A.; Nishino, Y.; Tsuji, I. Citrus consumption and cancer incidence: The Ohsaki cohort study. Int. J. Cancer 2010, 127, 1913–1922.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 1913-1922
-
-
Li, W.Q.1
Kuriyama, S.2
Li, Q.3
Nagai, M.4
Hozawa, A.5
Nishino, Y.6
Tsuji, I.7
-
271
-
-
18844447698
-
Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma—A multicentric european study
-
Dikshit, R.P.; Boffetta, P.; Bouchardy, C.; Merletti, F.; Crosignani, P.; Cuchi, T.; Ardanaz, E.; Brennan, P. Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma—A multicentric european study. Cancer 2005, 103, 2326–2333.
-
(2005)
Cancer
, vol.103
, pp. 2326-2333
-
-
Dikshit, R.P.1
Boffetta, P.2
Bouchardy, C.3
Merletti, F.4
Crosignani, P.5
Cuchi, T.6
Ardanaz, E.7
Brennan, P.8
-
272
-
-
41549083819
-
Citrus fruit intake and stomach cancer risk: A quantitative systematic review
-
Bae, J.M.; Lee, E.J.; Guyatt, G. Citrus fruit intake and stomach cancer risk: A quantitative systematic review. Gastric Cancer 2008, 11, 23–32.
-
(2008)
Gastric Cancer
, vol.11
, pp. 23-32
-
-
Bae, J.M.1
Lee, E.J.2
Guyatt, G.3
-
273
-
-
65349123512
-
Citrus fruit intake and pancreatic cancer risk: A quantitative systematic review
-
Bae, J.M.; Lee, E.J.; Guyatt, G. Citrus fruit intake and pancreatic cancer risk: A quantitative systematic review. Pancreas 2009, 38, 168–174.
-
(2009)
Pancreas
, vol.38
, pp. 168-174
-
-
Bae, J.M.1
Lee, E.J.2
Guyatt, G.3
-
274
-
-
84876081750
-
Citrus fruit intake and breast cancer risk: A quantitative systematic review
-
Song, J.K.; Bae, J.M. Citrus fruit intake and breast cancer risk: A quantitative systematic review. J. Breast Cancer 2013, 16, 72–76.
-
(2013)
J. Breast Cancer
, vol.16
, pp. 72-76
-
-
Song, J.K.1
Bae, J.M.2
-
275
-
-
84911936573
-
Citrus fruit intake and bladder cancer risk: A meta-analysis of observational studies
-
Liang, S.; Lv, G.; Chen, W.; Jiang, J.; Wang, J. Citrus fruit intake and bladder cancer risk: A meta-analysis of observational studies. Int. J. Food Sci. Nutr. 2014, 65, 893–898.
-
(2014)
Int. J. Food Sci. Nutr
, vol.65
, pp. 893-898
-
-
Liang, S.1
Lv, G.2
Chen, W.3
Jiang, J.4
Wang, J.5
-
276
-
-
84937511203
-
Fruits and vegetables intake and risk of bladder cancer: A prisma-compliant systematic review and dose-response meta-analysis of prospective cohort studies
-
Xu, C.; Zeng, X.T.; Liu, T.Z.; Zhang, C.; Yang, Z.H.; Li, S.; Chen, X.Y. Fruits and vegetables intake and risk of bladder cancer: A prisma-compliant systematic review and dose-response meta-analysis of prospective cohort studies. Medicine 2015, 94, e759.
-
(2015)
Medicine
, pp. 94
-
-
Xu, C.1
Zeng, X.T.2
Liu, T.Z.3
Zhang, C.4
Yang, Z.H.5
Li, S.6
Chen, X.Y.7
-
277
-
-
84911808068
-
Intake of fruit and vegetables and risk of bladder cancer: A dose-response meta-analysis of observational studies
-
Yao, B.; Yan, Y.; Ye, X.; Fang, H.; Xu, H.; Liu, Y.; Li, S.; Zhao, Y. Intake of fruit and vegetables and risk of bladder cancer: A dose-response meta-analysis of observational studies. Cancer Causes Control 2014, 25, 1645–1658.
-
(2014)
Cancer Causes Control
, vol.25
, pp. 1645-1658
-
-
Yao, B.1
Yan, Y.2
Ye, X.3
Fang, H.4
Xu, H.5
Liu, Y.6
Li, S.7
Zhao, Y.8
-
278
-
-
84943195304
-
Citrus fruit intake substantially reduces the risk of esophageal cancer: A meta-analysis of epidemiologic studies
-
Wang, A.; Zhu, C.; Fu, L.; Wan, X.; Yang, X.; Zhang, H.; Miao, R.; He, L.; Sang, X.; Zhao, H. Citrus fruit intake substantially reduces the risk of esophageal cancer: A meta-analysis of epidemiologic studies. Medicine 2015, 94, e1390.
-
(2015)
Medicine
, vol.94
-
-
Wang, A.1
Zhu, C.2
Fu, L.3
Wan, X.4
Yang, X.5
Zhang, H.6
Miao, R.7
He, L.8
Sang, X.9
Zhao, H.10
-
279
-
-
84966393677
-
An update of the WCRF/AICR systematic literature review on esophageal and gastric cancers and Citrus fruits intake
-
Vingeliene, S.; Chan, D.S.; Aune, D.; Vieira, A.R.; Polemiti, E.; Stevens, C.; Abar, L.; Rosenblatt, D.N.; Greenwood, D.C.; Norat, T. An update of the WCRF/AICR systematic literature review on esophageal and gastric cancers and Citrus fruits intake. Cancer Causes Control 2016, 27, 837–851.
-
(2016)
Cancer Causes Control
, vol.27
, pp. 837-851
-
-
Vingeliene, S.1
Chan, D.S.2
Aune, D.3
Vieira, A.R.4
Polemiti, E.5
Stevens, C.6
Abar, L.7
Rosenblatt, D.N.8
Greenwood, D.C.9
Norat, T.10
-
280
-
-
62449253972
-
Fruit and vegetable consumption and pancreatic cancer risk in the european prospective investigation into cancer and nutrition
-
Vrieling, A.; Verhage, B.A.; van Duijnhoven, F.J.; Jenab, M.; Overvad, K.; Tjonneland, A.; Olsen, A.; Clavel-Chapelon, F.; Boutron-Ruault, M.C.; Kaaks, R.; et al. Fruit and vegetable consumption and pancreatic cancer risk in the european prospective investigation into cancer and nutrition. Int. J. Cancer 2009, 124, 1926–1934.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 1926-1934
-
-
Vrieling, A.1
Verhage, B.A.2
Van Duijnhoven, F.J.3
Jenab, M.4
Overvad, K.5
Tjonneland, A.6
Olsen, A.7
Clavel-Chapelon, F.8
Boutron-Ruault, M.C.9
Kaaks, R.10
-
281
-
-
84989168199
-
Anti-inflammatory activity of Citrus bergamia derivatives: Where do we stand?
-
[CrossRef]
-
Ferlazzo, N.; Cirmi, S.; Calapai, G.; Ventura-Spagnolo, E.; Gangemi, S.; Navarra, M. Anti-inflammatory activity of Citrus bergamia derivatives: Where do we stand? Molecules 2016, 21, 1273. [CrossRef]
-
(2016)
Molecules
, vol.21
, pp. 1273
-
-
Ferlazzo, N.1
Cirmi, S.2
Calapai, G.3
Ventura-Spagnolo, E.4
Gangemi, S.5
Navarra, M.6
-
282
-
-
84991475852
-
Clinical Pharmacology of Citrus bergamia: A Systematic Review
-
[CrossRef]
-
Mannucci, C.; Navarra, M.; Calapai, F.; Squeri, R.; Gangemi, S.; Calapai, G. Clinical Pharmacology of Citrus bergamia: A Systematic Review. Phytother. Res. 2016. [CrossRef]
-
(2016)
Phytother. Res
-
-
Mannucci, C.1
Navarra, M.2
Calapai, F.3
Squeri, R.4
Gangemi, S.5
Calapai, G.6
-
283
-
-
84992391451
-
Neurodegenerative diseases: Might Citrus flavonoids play a protective role?
-
[CrossRef]
-
Cirmi, S.; Ferlazzo, N.; Lombardo, G.E.; Ventura-Spagnolo, E.; Gangemi, S.; Calapai, G.; Navarra, M. Neurodegenerative diseases: Might Citrus flavonoids play a protective role? Molecules 2016, 21, 1312. [CrossRef]
-
(2016)
Molecules
, vol.21
, pp. 2016
-
-
Cirmi, S.1
Ferlazzo, N.2
Lombardo, G.E.3
Ventura-Spagnolo, E.4
Gangemi, S.5
Calapai, G.6
Navarra, M.7
-
284
-
-
84988941446
-
The anticonvulsant activity of a flavonoid-rich extract from orange juice involves both NMDA and GABA-benzodiazepine receptor complexes
-
[CrossRef]
-
Citraro, R.; Navarra, M.; Leo, A.; Donato Di Paola, E.; Santangelo, E.; Lippiello, P.; Aiello, R.; Russo, E.; De Sarro, G. The anticonvulsant activity of a flavonoid-rich extract from orange juice involves both NMDA and GABA-benzodiazepine receptor complexes. Molecules 2016, 21. [CrossRef]
-
(2016)
Molecules
, vol.21
-
-
Citraro, R.1
Navarra, M.2
Leo, A.3
Donato Di Paola, E.4
Santangelo, E.5
Lippiello, P.6
Aiello, R.7
Russo, E.8
De Sarro, G.9
-
285
-
-
78650912735
-
Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy
-
Efferth, T.; Koch, E. Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy. Curr. Drug Targets 2011, 12, 122–132.
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 122-132
-
-
Efferth, T.1
Koch, E.2
|