Flavonoids increase the intracellular glutathione level by transactivation of the γ-glutamylcysteine synthetase catalytical subunit promoter

Free Radical Biology and Medicine

Volumn 32, Issue 5, 2002, Pages 386-393

  Myhrstad, Mari C W ^a   Carlsen, Harald ^a   Nordström, Olov ^a   Blomhoff, Rune ^a,b   Moskaug, Jan Øivind ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Glutamylcysteine synthetase; Antioxidant response element; Electrophile response element; Flavonoids; Free radicals; Glutathione

Indexed keywords

APIGENIN; FLAVANOID; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; KAEMPFEROL; MYRICETIN; ONION EXTRACT; QUERCETIN; ANTINEOPLASTIC AGENT; FLAVONOID; KAEMPFEROL DERIVATIVE; LUCIFERASE; MESSENGER RNA; PRIMER DNA; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CANCER; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVATION; ENZYME ACTIVE SITE; GENE CONTROL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; DIET; DRUG EFFECT; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; ONION; PLASMID; POLYMERASE CHAIN REACTION; REGULATORY SEQUENCE; TRANSACTIVATION;

ANIMAL; ANTINEOPLASTIC AGENTS; CERCOPITHECUS AETHIOPS; COS CELLS; DIET; DNA PRIMERS; FLAVONES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; LUCIFERASE; ONIONS; PLASMIDS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN SUBUNITS; QUERCETIN; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SEQUENCE DELETION; SUPPORT, NON-U.S. GOV'T; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; ANIMALS; APIGENIN; FLAVONOIDS; KAEMPFEROLS; LUCIFERASES;

ALLIUM CEPA;

EID: 0036489186     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00812-7     Document Type: Article

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