Naringenin-induced apoptosis via activation of NF-κB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells

Toxicology Letters

Volumn 166, Issue 2, 2006, Pages 131-139

  Kanno, Syu ichi ^a   Tomizawa, Ayako ^a   Ohtake, Takaharu ^a   Koiwai, Kimiko ^a   Ujibe, Mayuko ^a   Ishikawa, Masaaki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; ATP; Mitochondria; Naringenin; Necrosis; NF B

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; FLAVONOID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NARINGENIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPERPOLARIZATION; INCUBATION TIME; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLAVANONES; HL-60 CELLS; HUMANS; INTRACELLULAR MEMBRANES; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE POTENTIALS; MITOCHONDRIA; NECROSIS; NF-KAPPA B;

EID: 33747881688     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2006.06.005     Document Type: Article

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