Nobiletin inhibits epithelial-mesenchymal transition of human non-small cell lung cancer cells by antagonizing the TGF-β1/Smad3 signaling pathway

Oncology Reports

Volumn 35, Issue 5, 2016, Pages 2767-2774

  Da, Chunli ^a   Liu, Yuting ^a   Zhan, Yiyi ^a   Liu, Kai ^a   Wang, Ruozheng ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Epithelial mesenchymal transition; Invasion; Nobiletin; NSCLC; TGF Smads

Indexed keywords

CYCLOPHOSPHAMIDE; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; NOBILETIN; PAXILLIN; PROTEIN TYROSINE KINASE; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA1; ANTINEOPLASTIC AGENT; FLAVONE DERIVATIVE; SMAD3 PROTEIN, HUMAN; TGFB1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG ANTAGONISM; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; METASTASIS INHIBITION; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; A-549 CELL LINE; ANIMAL; CARCINOMA, NON-SMALL-CELL LUNG; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; GENETIC TRANSCRIPTION; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; SECONDARY;

A549 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL ADHESION; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FLAVONES; HUMANS; LUNG NEOPLASMS; MICE, NUDE; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA1; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84964054338     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2016.4661     Document Type: Article

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