Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway

Journal of Cellular Physiology

Volumn 230, Issue 8, 2015, Pages 1729-1739

  Palit, Shreyasi ^a   Kar, Susanta ^b   Sharma, Gunjan ^c   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b CSIR Central Drug Reserch Institute   (India)

^c LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOPTOSIS SIGNAL REGULATING KINASE 1; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CASPASE 7; CASPASE 9; CYTOCHROME C; DIHYDRORHODAMINE 123; GLUTATHIONE; HESPERETIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTINEOPLASTIC AGENT; HESPERIDIN; MAP3K5 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM CELL; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MCF 7 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PREMEDICATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; BREAST TUMOR; DRUG EFFECTS; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; TUNEL ASSAY;

CITRUS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; ENZYME ACTIVATION; FLOW CYTOMETRY; HESPERIDIN; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84928393491     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24818     Document Type: Article

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