Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt

International Journal of Oncology

Volumn 40, Issue 6, 2012, Pages 2090-2096

  Han, Min Ho ^a,e   Lee, Won Sup ^b   Lu, Jing Nan ^b   Kim, Gonsup ^c   Jung, Jin Myung ^b   Ryu, Chung Ho ^c   Kim, G I Young ^d   Hwang, Hye Jin ^e   Kwon, Taeg Kyu ^f   Choi, Yung Hyun ^a  

^a Dong Eui University   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

^c Gyeongsang National University   (South Korea)

^d Jeju National University   (South Korea)

^e Dong Eui University   (South Korea)

^f Keimyung University   (South Korea)

Author keywords

Akt; Apoptosis; Citrus aurantium L; Leukemia; U937 cells

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; METHANOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHOLIPASE C GAMMA1; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN KINASE B; SOUR ORANGE EXTRACT; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN U937; CELL VIABILITY; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SOUR ORANGE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; CELL PROLIFERATION; CELL SURVIVAL; CITRUS; ENZYME ACTIVATION; FRUIT; HUMANS; INHIBITORY CONCENTRATION 50; LEUKEMIA; PHOSPHORYLATION; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; U937 CELLS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84861790533     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1350     Document Type: Article

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