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Volumn 1823, Issue 2, 2012, Pages 593-604

Evidence for activation of mutated p53 by apigenin in human pancreatic cancer

Author keywords

Apoptosis; P53; Pancreatic cancer; PUMA

Indexed keywords

APIGENIN; CYTOCHROME C; DNA BINDING PROTEIN; PIFITHRIN ALPHA; PROTEIN BCL XL; PROTEIN P21; PROTEIN P53; PUMA PROTEIN;

EID: 84862779346     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.12.008     Document Type: Article
Times cited : (60)

References (29)
  • 1
    • 0033559213 scopus 로고    scopus 로고
    • An investigational new drug treatment program for patients with gemcitabine: results for over 3000 patients with pancreatic carcinoma
    • Storniolo A.M., Enas N.H., Brown C.A., Voi M., Rothenberg M.L., Schilsky R. An investigational new drug treatment program for patients with gemcitabine: results for over 3000 patients with pancreatic carcinoma. Cancer 1999, 85:1261-1268.
    • (1999) Cancer , vol.85 , pp. 1261-1268
    • Storniolo, A.M.1    Enas, N.H.2    Brown, C.A.3    Voi, M.4    Rothenberg, M.L.5    Schilsky, R.6
  • 2
    • 33744828685 scopus 로고    scopus 로고
    • Bioavailability of apigenin from apiin-rich parsley in humans
    • Meyer H., Bolarinwa A., Wolfram G., Linseisen J. Bioavailability of apigenin from apiin-rich parsley in humans. Ann. Nutr. Metab. 2006, 50:167-172.
    • (2006) Ann. Nutr. Metab. , vol.50 , pp. 167-172
    • Meyer, H.1    Bolarinwa, A.2    Wolfram, G.3    Linseisen, J.4
  • 4
    • 66149148328 scopus 로고    scopus 로고
    • The flavonoid apigenin potentiates the growth inhibitory effects of gemcitabine and abrogates gemcitabine resistance in human pancreatic cancer cells
    • Strouch M.J., Milam B.M., Melstrom L.G., McGill J.J., Salabat M.R., Ujiki M.B., Ding X.Z., Bentrem D.J. The flavonoid apigenin potentiates the growth inhibitory effects of gemcitabine and abrogates gemcitabine resistance in human pancreatic cancer cells. Pancreas 2009, 38:409-415.
    • (2009) Pancreas , vol.38 , pp. 409-415
    • Strouch, M.J.1    Milam, B.M.2    Melstrom, L.G.3    McGill, J.J.4    Salabat, M.R.5    Ujiki, M.B.6    Ding, X.Z.7    Bentrem, D.J.8
  • 5
    • 79952681368 scopus 로고    scopus 로고
    • Induction of apoptotic cell death by phytoestrogens by up-regulating the levels of phospho-p53 and p21 in normal and malignant estrogen receptor α-negative breast cells
    • Seo H.S., Ju J.H., Jang K., Shin I. Induction of apoptotic cell death by phytoestrogens by up-regulating the levels of phospho-p53 and p21 in normal and malignant estrogen receptor α-negative breast cells. Nutr. Res. 2011, 31:139-146.
    • (2011) Nutr. Res. , vol.31 , pp. 139-146
    • Seo, H.S.1    Ju, J.H.2    Jang, K.3    Shin, I.4
  • 7
    • 55949083781 scopus 로고    scopus 로고
    • Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage
    • Cai X., Liu X. Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:16958-16963.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 16958-16963
    • Cai, X.1    Liu, X.2
  • 9
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 2001, 7:683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 10
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: news from the mutant p53 field
    • Brosh R., Rotter B. When mutants gain new powers: news from the mutant p53 field. Nat. Rev. 2009, 9:701-713.
    • (2009) Nat. Rev. , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, B.2
  • 11
    • 0033552948 scopus 로고    scopus 로고
    • Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
    • Blandino G., Levine A.J., Oren M. Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 1999, 18:477-485.
    • (1999) Oncogene , vol.18 , pp. 477-485
    • Blandino, G.1    Levine, A.J.2    Oren, M.3
  • 12
    • 0031000441 scopus 로고    scopus 로고
    • Evaluation of properties of apigenin and [G-3H] apigenin and analytic method development
    • Boyong L., Robinson D.H., Birt D.F. Evaluation of properties of apigenin and [G-3H] apigenin and analytic method development. J. Pharm. Sci. 1997, 86:721-725.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 721-725
    • Boyong, L.1    Robinson, D.H.2    Birt, D.F.3
  • 17
    • 0026663706 scopus 로고
    • Human pancreatic adenocarcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes
    • Ruggeri B., Zhang S.Y., Caamano J., DiRado M., Flynn S.D., Klein-Szanto A.J. Human pancreatic adenocarcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes. Oncogene 1992, 7:1503-1511.
    • (1992) Oncogene , vol.7 , pp. 1503-1511
    • Ruggeri, B.1    Zhang, S.Y.2    Caamano, J.3    DiRado, M.4    Flynn, S.D.5    Klein-Szanto, A.J.6
  • 18
    • 0032768368 scopus 로고    scopus 로고
    • P53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer
    • Hussain S.P., Harris C.C. p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer. Mutat. Res. 1999, 428:23-32.
    • (1999) Mutat. Res. , vol.428 , pp. 23-32
    • Hussain, S.P.1    Harris, C.C.2
  • 20
  • 25
    • 0034629291 scopus 로고    scopus 로고
    • P53 induces apoptosis by caspace activation through mitochondrial cytochrome c release
    • Schuler M., Bossy-Wetzl E., Goldstein J.C., Fitzgerald P., Green D.R. p53 induces apoptosis by caspace activation through mitochondrial cytochrome c release. J. Biol. Chem. 2000, 275:7337-7342.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7337-7342
    • Schuler, M.1    Bossy-Wetzl, E.2    Goldstein, J.C.3    Fitzgerald, P.4    Green, D.R.5
  • 26
    • 0030842112 scopus 로고    scopus 로고
    • Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase c inhibition
    • Agullo G., Gamet-Payrastre L., Manenti S., Viala C., Remesy C., Chap H., Payrastre B. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase c inhibition. Biochem. Pharmacol. 1997, 53:1649-1657.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1649-1657
    • Agullo, G.1    Gamet-Payrastre, L.2    Manenti, S.3    Viala, C.4    Remesy, C.5    Chap, H.6    Payrastre, B.7
  • 28
    • 36849075271 scopus 로고    scopus 로고
    • Enhanced anti-tumor effect of combination therapy with gemcitabine and apigenin in pancreatic cancer
    • Lee S.H., Ryu J.K., Lee K.Y., Woo S.M., Park J.K., Yoo J.W., Kim Y.T., Yoon Y.B. Enhanced anti-tumor effect of combination therapy with gemcitabine and apigenin in pancreatic cancer. Cancer Lett. 2005, 259:39-49.
    • (2005) Cancer Lett. , vol.259 , pp. 39-49
    • Lee, S.H.1    Ryu, J.K.2    Lee, K.Y.3    Woo, S.M.4    Park, J.K.5    Yoo, J.W.6    Kim, Y.T.7    Yoon, Y.B.8
  • 29
    • 34248226610 scopus 로고    scopus 로고
    • Apigenin and cancer chemoprevention: progress, potential and promise (a review)
    • Patel D., Shukla S., Gupta S. Apigenin and cancer chemoprevention: progress, potential and promise (a review). Int. J. Oncol. 2007, 30:233-245.
    • (2007) Int. J. Oncol. , vol.30 , pp. 233-245
    • Patel, D.1    Shukla, S.2    Gupta, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.