Inhibition of oral carcinogenesis by citrus flavonoids

Nutrition and Cancer

Volumn 60, Issue 1, 2008, Pages 69-74

  Miller, Edward G ^a,b   Peacock, Jason J ^a   Bourland, T Campbell ^a   Taylor, Samuel E ^a   Wright, John M ^a   Patil, Bhimanagouda S ^b  

^a BAYLOR COLLEGE OF DENTISTRY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; AURANTIIN; BIOFLAVONOID; CARCINOGEN; HESPERETIN; NARINGENIN; NEOHESPERIDIN; NOBILETIN; TANGERETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CARCINOGENESIS; CHEEK POUCH; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; GRAPEFRUIT; HAMSTER; MOUTH CANCER; NONHUMAN; RAT; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRUS; CRICETINAE; FLAVANONES; FLAVONES; FLAVONOIDS; HESPERIDIN; MOUTH NEOPLASMS; RANDOM ALLOCATION;

CITRUS; CITRUS X PARADISI; CRICETINAE;

EID: 38749126787     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635580701616163     Document Type: Article

References (46)

1. Middleton E and Kandaswami C: Potential health-promoting properties of citrus flavonoids. Food Technol 48, 115-119, 1994.
2. Block G: Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr 53, 270s-282s, 1991.
3. Lam LKT and Hasegawa S: Inhibition of benz[a]pyrene-induced forestomach neoplasia in mice by citrus limonoids. Nutr Cancer 12, 43-47, 1989.
4. Miller EG, Fanous R, Rivera-Hidalgo F, Binnie WH, Hasegawa S, et al.: The effect of citrus limonoids on hamster buccal pouch carcinogenesis. Carcinogenesis 10, 1535-1537, 1989.
5. Miller EG, Gonzales-Sanders AP, Couvillon AM, Wright JM, Hasegawa S, et al.: Inhibition of hamster buccal pouch carcinogenesis by limonin 17-β-D-glucopyranoside. Nutr Cancer 17, 1-7, 1992.
6. Lam LKT, Zhang J, and Hasegawa S: Citrus limonoid reduction of chemically induced tumorigenesis. Food Technol 48, 104-108, 1994.
7. Miller EG, Gonzales-Sanders AP, Couvillon AM, Binnie WH, Hasegawa S, et al.: Citrus limonoids as inhibitors of oral carcinogenesis. Food Technol 48, 110-114, 1994.
8. Lam LKT, Zhang J, Hasegawa S, and Schut HAJ: Inhibition of chemically induced carcinogenesis by citrus limonoids. In Food Phytochemicals for Cancer Prevention I: Fruits and Vegetables, Huang M-T, Osawa T, Ho C-T, and Rosen RT (eds.). Washington, DC: American Chemical Society, 1994, pp. 209-219.
9. Miller EG, Gonzales-Sanders AP, Couvillon AM, Wright JM, Hasegawa S, et al.: Inhibition of oral carcinogenesis by green coffee beans and limonoid glucosides. In Food Phytochemicals for Cancer Prevention I: Fruits and Vegetables, Huang M-T, Osawa T, Ho C-T, and Rosen RT (eds.). Washington, DC; American Chemical Society, 1994, pp. 220-229.
10. Miller EG, Porter-Wright JL, Binnie WH, Guo IY, and Hasegawa S: The importance of the B-ring of the limonoid nucleus to the cancer chemopreventive activity of citrus limonoids. In Hypernutritious Foods, Finley JW, Armstrong DJ, Nagy S, and Robinson SF (eds.). Auburndale, FL: Agscience Inc., 1996, pp. 191-204.
11. Tanaka T, Ota T, Miyake M, and Wada K: Citrus limonoids obacunone and limonin inhibit the development of a precursor lesion, aberrant crypt foci for colon cancer in rats. In Citrus Limonoids Functional Chemicals in Agriculture and Foods, Berhow M, Hasegawa S, and Manners G (eds.). Washington, DC: American Chemical Society, 2000, pp. 145-163.
12. Lam LKT, Hasegawa S, Bergstrom C, Lam SH, and Kenney P: Limonin and nomilin inhibitory effects on chemical-induced carcinogenesis. In Citrus Limonoids Functional Chemicals in Agriculture and Foods, Berhow M, Hasegawa S, and Manners G (eds.). Washington, DC: American Chemical Society, 2000, pp. 185-200.
13. Miller EG, Porter JL, Binnie WH, Guo IY, and Hasegawa S: Further studies on the anticancer activity of citrus limonoids. J Agric Food Chem 52, 4908-4912, 2004.
14. Hasegawa S, Bennett RD, Herman Z, Fong CH, and Ou P: Limonoid glucosides in citrus. Phytochemistry 28, 1717-1720, 1989.
15. Bennett RD, Hasegawa S, and Herman Z: Glucosides of acidic limonoids in citrus. Phytochemistry 28, 2777-2781, 1989.
16. Hasegawa S, Ou P, Fong CH, Herman Z, Coggins CW, et al.: Changes in the limonate A-ring lactone and limonin 17-β-D-glucopyranoside content of navel oranges during fruit growth and maturation. J Agric Food Chem 39, 262-265, 1991.
17. Herman Z, Fong CH, Ou P and Hasegawa S: Limonoid glucosides in commercial citrus juices by HPLC. J Agric Food Chem 38, 1860-1861, 1990.
18. Fong CH, Hasegawa S, Herman Z, and Ou P: Limonoid glucosides in commercial citrus juices. J Food Sci 54, 1505-1506, 1990.
19. Miller EG, McWhorter K, Rivera-Hidalgo F, Wright JM, Hirsbrunner P, et al.: Kahweol and cafestol: inhibitors of hamster buccal pouch carcinogenesis. Nutr Cancer 15, 41-46, 1991.
20. Niukian K, Schwartz J, and Shklar G: Effects of onion extract on the development of hamster buccal pouch carcinomas as expressed in tumor burden. Nutr Cancer 9, 171-176, 1987.
21. Kandaswami C, Perkins E, Soloniuk DS, Drzewiecki G, and Middleton E: Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro. Cancer Lett 56, 147-152, 1991.
22. Kandaswami C, Perkins E, Drzewiecki G, Soloniuk DS, and Middleton E: Differential inhibition of proliferation of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids. Anticancer Drugs 3, 525-530, 1992.
23. Rodriguez J, Yanez J, Vicente V, Alcaraz M, Benawente-Garcia O, et al.: Effects of several flavonoids on the growth of B16F10 and SK-MEL-1 melanoma cell lines: relationship between structure and activity. Melanoma Res 12, 99-107, 2002.
24. Le Bon AM, Siess MH, and Suschetet M: Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats. Chem Biol Interact 83, 65-71, 1992.
25. Siess MH, Le Bon AM, Canivenc-Lavier M-C, and Suschetet M: Mechanisms involved in the chemoprevention of flavonoids. Biofactors 12, 193-199, 2000.
26. Bracke M, Vyncke BM, Van Larebeke NA, Bruyneel EA, De Bruyne GK, et al.: The flavonoid tangeretin inhibits invasion of MO4 mouse cells into embryonic chick heart in vitro. Clin Exp Metastasis 7, 283-300, 1989.
27. Bracke M, Vyncke B, Opdenakker G, Foidart JM, De Pestel G, et al.: Effect of catechins and citrus flavonoids on invasion in vitro. Clin Exp Metastasis 9, 13-25, 1991.
28. Bracke ME, Bruyneel EA, Vermeulen SJ, Vennekens K, Van Marck V, et al.: Citrus flavonoid effect on tumor invasion and metastasis. Food Technol 48, 121-124, 1994.
29. Bracke ME, Boterberg T, Depypere HT, Stove C, Leclercq G, et al.: The citrus methoxyflavone tangeretin affects human cell-cell interactions. Adv Exp Med Biol 505, 135-139, 2002.
30. Bracke ME, Depypere HT, Boterberg T, Van Marck VL, Vennekens KM, et al.: Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer. JNCI 91, 354-359, 1999.
31. Odukoya O and Shklar G: Two-phase carcinogenesis in hamster buccal pouch. Oral Surg 54, 547-552, 1982.
32. Sawa T, Nakao M, Akaike T, Ono K, and Maeda H: Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor promoter effect of vegetables. J Agric Food Chem 47, 397-402, 1999.
33. Sawa T, Akaike T, Kida K, Fukushima Y, Takagi K, et al.: Lipid peroxyradicals from oxidized oils and heme-iron: implication of fat diet in colon carcinogenesis. Cancer Epidemiol Biomarkers Prev 7, 1007-1012, 1998.
34. Yu J, Wang L, Walzem RL, Miller EG, Pike LM, et al.: Antioxidant activity of citrus limonoids, flavonoids, and coumarins. J Agric Food Chem 53, 2009-2014, 2005.
35. Kim JY, Jung KJ, Choi JS, and Chung HY: Hesperetin: a potent antioxidant against peroxynitrite. Free Radic Res 38, 761-769, 2004.
36. So FV, Guthrie N, Chambers AF, Moussa M, and Carroll KK: Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutr Cancer 26, 167-181, 1996.
37. Kanno S, Tomizawa A, Hiura T, Osanai Y, Shouji A, et al.: Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice. Biol Pharm Bull 28, 527-530, 2005.
38. Bear WL and Teel RW: Effects of citrus phytochemicals on liver and lung cytochrome P450 activity and on the in vitro metabolism of the tobacco-specific nitrosamine NNK. Anticancer Res 20, 3323-3330, 2000.
39. Bear WL and Teel RW: Effects of citrus flavonoids on the mutagenicity of heterocyclic amines and on cytochrome P450 1A2 activity. Anticancer Res 20, 3609-3614, 2000.
40. Le Marchand L, Murphy SP, Hankin JH, Wilkens LR, and Kolonel LN: Intake of flavonoids and lung cancer. JNCI 92, 154-160, 2000.
41. Jagetia GC and Reddy TK: The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow: a micronucleus study. Mutat Res 519, 37-48, 2002.
42. Suda D, Schwartz J, and Shklar G: Inhibition of experimental oral carcinogenesis by topical beta carotene. Carcinogenesis 7, 711-715, 1986.
43. Shklar G, Schwartz J, Trickler D, and Cheverie SR: The effectiveness of a mixture of β-carotene, α-tocopherol, glutathione, and ascorbic acid for cancer prevention. Nutr Cancer 20, 145-151, 1993.
44. Turner ND, Vanamala J, Leonardi T, Patil BS, Murphy ME, et al.: Comparison of the chemoprotection conferred by grapefruit and isolated bioactive compounds against colon cancer. In Potential Health Benefits of Citrus, Patil BS, Turner ND, Miller EG, and Brodbelt JS (eds). Washington, DC: American Chemical Society, 2006, pp. 121-129.
45. Patil BS: Enhancing citrus phytochemicals. Proc Intl Citricult IX Congr II, 1184-1187, 2000.
46. Gao K, Henning SM, Niu Y, Youssefian AA, Seeram NP, et al.: The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells. J Nutr Biochem 17, 89-95, 2006.