Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells

Molecular and Cellular Biochemistry

Volumn 347, Issue 1-2, 2011, Pages 103-115

  Lee, Yi Chieh ^a   Cheng, Tsan Hwang ^a   Lee, Jung Shin ^a   Chen, Jiun Hwan ^b   Liao, Yi Chen ^b   Fong, Yao ^b   Wu, Cheng Hsun ^c   Shih, Yuan Wei ^a  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

FAK; Invasion; Migration; MMP 2; MMP 9; Nobiletin; PI3K Akt

Indexed keywords

BETA ACTIN; COMPLEMENTARY DNA; FOCAL ADHESION KINASE 1; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NOBILETIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN CDC42; RAC1 PROTEIN; RAF PROTEIN; RAS PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA BINDING; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; OUTCOME ASSESSMENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

ACTINS; ADENOCARCINOMA; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SHAPE; CELL SURVIVAL; CITRUS; CYTOSKELETON; DNA, NEOPLASM; FLAVONES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; I-KAPPA B PROTEINS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MONOMERIC GTP-BINDING PROTEINS; NEOPLASM INVASIVENESS; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

CITRUS;

EID: 78651303014     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0618-z     Document Type: Article

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