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Volumn 58, Issue 12, 2006, Pages 1655-1660

Inhibitory effect of apigenin on benzo(a)pyrene-mediated genotoxicity in Swiss albino mice

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; BENZO[A]PYRENE; CYTOCHROME P450; GLUTATHIONE; GLUTATHIONE TRANSFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNSPECIFIC MONOOXYGENASE;

EID: 33846002359     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.58.12.0013     Document Type: Article
Times cited : (28)

References (45)
  • 1
    • 0019142866 scopus 로고
    • Increase of NADPH; quinone reductase activity by dietary antioxidant: Possible role in protection against carcinogenesis and toxicity
    • Benson, A. M., Hunkeler, M. J., Talalay, P. (1980) Increase of NADPH; quinone reductase activity by dietary antioxidant: possible role in protection against carcinogenesis and toxicity. Proc. Natl Acad. Sci. USA 77: 5216-5220
    • (1980) Proc. Natl Acad. Sci. USA , vol.77 , pp. 5216-5220
    • Benson, A.M.1    Hunkeler, M.J.2    Talalay, P.3
  • 2
    • 0034846868 scopus 로고    scopus 로고
    • Antioxidant and antiradical activities of flavonoids
    • Burda, S., Oleszek W. (2001) Antioxidant and antiradical activities of flavonoids. J. Agr. Food Chem. 49: 2774-2779
    • (2001) J. Agr. Food Chem , vol.49 , pp. 2774-2779
    • Burda, S.1    Oleszek, W.2
  • 3
    • 32844458451 scopus 로고    scopus 로고
    • Mechanisms of eukaryotic DNA double strand break repair
    • Cahill, D., Connor, B., Carney, J. P. (2006) Mechanisms of eukaryotic DNA double strand break repair. Front. Biosci. 11: 1958-1976
    • (2006) Front. Biosci , vol.11 , pp. 1958-1976
    • Cahill, D.1    Connor, B.2    Carney, J.P.3
  • 4
    • 0029901332 scopus 로고    scopus 로고
    • Cytochromes P450 (CYP) in the Poeciliopsis lucida hepatocellular carcinoma cell line (PLHC-1): Dose- and time-dependent glucocorticoid potentiation of CYP1A induction without induction of CYP3A
    • Celander, M., Hahn, M. E., Stegeman, J. J. (1996) Cytochromes P450 (CYP) in the Poeciliopsis lucida hepatocellular carcinoma cell line (PLHC-1): dose- and time-dependent glucocorticoid potentiation of CYP1A induction without induction of CYP3A. Arch. Biochem. Biophys. 329: 113-122
    • (1996) Arch. Biochem. Biophys , vol.329 , pp. 113-122
    • Celander, M.1    Hahn, M.E.2    Stegeman, J.J.3
  • 5
    • 0018568031 scopus 로고
    • Improved microfluorometric DNA determination in biological material using 33258 Hoechst
    • Cesarone, C, F., Bolognesi, C., Santi, L. (1979) Improved microfluorometric DNA determination in biological material using 33258 Hoechst. Anal. Biochem. 100: 188-197
    • (1979) Anal. Biochem , vol.100 , pp. 188-197
    • Cesarone, C.F.1    Bolognesi, C.2    Santi, L.3
  • 7
    • 27744606731 scopus 로고    scopus 로고
    • Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells
    • Jul 12 E-pub ahead of print
    • Chiang, L. C., Ng, L. T., Lin, I. C., Kuo, P. L., Lin, C. C. (2005) Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells. Cancer Lett. 2005 Jul 12 (E-pub ahead of print)
    • (2005) Cancer Lett
    • Chiang, L.C.1    Ng, L.T.2    Lin, I.C.3    Kuo, P.L.4    Lin, C.C.5
  • 8
    • 26044481983 scopus 로고    scopus 로고
    • Dietary flavonoids as intracellular substrates for an erythrocyte trans-plasma membrane oxidoreductase activity
    • Fiorani, M., Accorsi, A. (2005) Dietary flavonoids as intracellular substrates for an erythrocyte trans-plasma membrane oxidoreductase activity. Br. J. Nutr. 94: 338-345
    • (2005) Br. J. Nutr , vol.94 , pp. 338-345
    • Fiorani, M.1    Accorsi, A.2
  • 9
    • 0023686219 scopus 로고
    • Mechanisms of inhibition of mutagenesis and carcinogenesis. Classification and overview
    • De Flora, S., Ramel, C. (1988) Mechanisms of inhibition of mutagenesis and carcinogenesis. Classification and overview. Mutat. Res. 202: 285-306
    • (1988) Mutat. Res , vol.202 , pp. 285-306
    • De Flora, S.1    Ramel, C.2
  • 10
    • 0023951396 scopus 로고
    • Roles of cytochrome P450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • Guengerich, F. P. (1988) Roles of cytochrome P450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 48: 2946-2954
    • (1988) Cancer Res , vol.48 , pp. 2946-2954
    • Guengerich, F.P.1
  • 11
    • 0016275313 scopus 로고
    • GST the first enzymatic step in mercapturic acid formation
    • Habig, W. H., Pubst, M. J., Jokoby, W. B. (1974) GST the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249: 7130-7139
    • (1974) J. Biol. Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pubst, M.J.2    Jokoby, W.B.3
  • 12
    • 0026636441 scopus 로고
    • Free radicals, antioxidants, and human disease: Where are we now?
    • Halliwell, B., Gutteridge, J. M. C., Cross, C. E. (1992) Free radicals, antioxidants, and human disease: where are we now? J. Lab. Clin. Med. 119: 598-620
    • (1992) J. Lab. Clin. Med , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.C.2    Cross, C.E.3
  • 13
    • 0027053231 scopus 로고
    • Mechanisms by which benzo(a)pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis
    • Hardin, J. A., Hinoshita, F., Sherr, D. H. (1992) Mechanisms by which benzo(a)pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis. Toxicol. Appl. Pharmacol. 117: 155-164
    • (1992) Toxicol. Appl. Pharmacol , vol.117 , pp. 155-164
    • Hardin, J.A.1    Hinoshita, F.2    Sherr, D.H.3
  • 14
    • 0025283870 scopus 로고
    • Antimutagens and anticarcinogens; a survey of putative interceptor molecules
    • Hartman, P. E., Shankel, D. W. (1990) Antimutagens and anticarcinogens; a survey of putative interceptor molecules. Environ. Mol. Mutagen. 15: 145-182
    • (1990) Environ. Mol. Mutagen , vol.15 , pp. 145-182
    • Hartman, P.E.1    Shankel, D.W.2
  • 17
    • 24044440400 scopus 로고    scopus 로고
    • Apigenin inhibits oxidative stress-induced macromolecular damage in N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinogenesis in Wistar albino rats
    • Jeyabal, P. V., Syed, M. B., Venkataraman, M., Sambandham, J. K., Sakthisekaran, D. (2005) Apigenin inhibits oxidative stress-induced macromolecular damage in N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinogenesis in Wistar albino rats. Mol. Carcinog. 44: 11-20
    • (2005) Mol. Carcinog , vol.44 , pp. 11-20
    • Jeyabal, P.V.1    Syed, M.B.2    Venkataraman, M.3    Sambandham, J.K.4    Sakthisekaran, D.5
  • 18
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobezene oxide as the hepatotoxic metabolite
    • Jollow, D. J., Mitchell, J. R., Zampaglione, N., Gillette, J. R. (1974) Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobezene oxide as the hepatotoxic metabolite. Pharmacology 11: 151
    • (1974) Pharmacology , vol.11 , pp. 151
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3    Gillette, J.R.4
  • 19
    • 28844454236 scopus 로고    scopus 로고
    • Apigenin induces apoptosis in Hep G2 cells: Possible role of TNF-alpha and IFN-gamma
    • Khan, T. H., Sultana, S. (2006) Apigenin induces apoptosis in Hep G2 cells: possible role of TNF-alpha and IFN-gamma. Toxicology 217: 206-212
    • (2006) Toxicology , vol.217 , pp. 206-212
    • Khan, T.H.1    Sultana, S.2
  • 20
    • 18044372810 scopus 로고    scopus 로고
    • Soy isoflavones inhibits the genotoxicity of benzo(a)pyrene in Swiss albino mice
    • Khan, T. H., Prasad, L., Anuradha, Sultana, S. (2005) Soy isoflavones inhibits the genotoxicity of benzo(a)pyrene in Swiss albino mice. Hum. Exp. Toxicol. 24: 149-155
    • (2005) Hum. Exp. Toxicol , vol.24 , pp. 149-155
    • Khan, T.H.1    Prasad, L.2
  • 21
    • 1042287097 scopus 로고    scopus 로고
    • Effects of genotoxic compounds on DNA and development of early and late grass shrimp embryo stages
    • Kim, G. B., Lee, R. F. (2004) Effects of genotoxic compounds on DNA and development of early and late grass shrimp embryo stages. Mar. Environ. Res. 57: 329-338
    • (2004) Mar. Environ. Res , vol.57 , pp. 329-338
    • Kim, G.B.1    Lee, R.F.2
  • 23
    • 21244450797 scopus 로고    scopus 로고
    • Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States)
    • Lin, J., Zhang, S. M., Cook, N. R., Rexrode, K. M., Liu, S., Manson, J. E., Lee, I. M., Buring, J. E. (2005) Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States). Cancer Causes Control 16: 225-233
    • (2005) Cancer Causes Control , vol.16 , pp. 225-233
    • Lin, J.1    Zhang, S.M.2    Cook, N.R.3    Rexrode, K.M.4    Liu, S.5    Manson, J.E.6    Lee, I.M.7    Buring, J.E.8
  • 25
    • 18544370739 scopus 로고    scopus 로고
    • Measurement of fruit and vegetable consumption with diet questionnaires and implications for analyses and interpretation
    • Michels, K. B., Welch, A. A., Luben, R., Bingham, S. A., Day, N. E. (2005) Measurement of fruit and vegetable consumption with diet questionnaires and implications for analyses and interpretation. Am. J. Epidemiol. 161: 987-994
    • (2005) Am. J. Epidemiol , vol.161 , pp. 987-994
    • Michels, K.B.1    Welch, A.A.2    Luben, R.3    Bingham, S.A.4    Day, N.E.5
  • 26
    • 0032549460 scopus 로고    scopus 로고
    • DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring
    • Mitchelmore, C. L., Chipman, J. K. (1998) DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring. Mutat. Res. 399: 135-147
    • (1998) Mutat. Res , vol.399 , pp. 135-147
    • Mitchelmore, C.L.1    Chipman, J.K.2
  • 27
    • 0037379946 scopus 로고    scopus 로고
    • Role of cytochrome P4501B1 in benzo(a)pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: Evidence from 32P-postlabeling for formation of 3-hydroxybenzo(a)pyrene and benzo(a)pyrene-3, 6-quinone as major proximate genotoxic intermediates
    • Moorthy, B., Miller, K. P., Jiang, W., Williams, E. S., Kondraganti, S. R., Ramos, K. S. (2003) Role of cytochrome P4501B1 in benzo(a)pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo(a)pyrene and benzo(a)pyrene-3, 6-quinone as major proximate genotoxic intermediates. J. Pharmacol. Exp. Ther. 305: 394-401
    • (2003) J. Pharmacol. Exp. Ther , vol.305 , pp. 394-401
    • Moorthy, B.1    Miller, K.P.2    Jiang, W.3    Williams, E.S.4    Kondraganti, S.R.5    Ramos, K.S.6
  • 28
    • 0027456898 scopus 로고
    • Effects of benzo(a)pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: Inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle
    • Mudzinski, S. P. (1993) Effects of benzo(a)pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle. Toxicol. Appl. Pharmacol. 119: 166-174
    • (1993) Toxicol. Appl. Pharmacol , vol.119 , pp. 166-174
    • Mudzinski, S.P.1
  • 29
    • 33344476097 scopus 로고    scopus 로고
    • DNA damage checkpoints in mammals
    • Niida, H., Nakanishi, M. (2006) DNA damage checkpoints in mammals. Mutagenesis 21: 3-9
    • (2006) Mutagenesis , vol.21 , pp. 3-9
    • Niida, H.1    Nakanishi, M.2
  • 30
    • 0004291866 scopus 로고    scopus 로고
    • NTP National Toxicology Program, 8th edn, National Institute of Environmental Health Sciences, Research Triangle Park, NC
    • NTP (National Toxicology Program) (1998) Report on carcinogens. 8th edn, National Institute of Environmental Health Sciences, Research Triangle Park, NC
    • (1998) Report on carcinogens
  • 31
    • 78651165715 scopus 로고
    • The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura, T., Sato, R. (1964) The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239: 2370-2378
    • (1964) J. Biol. Chem , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 32
    • 0032937593 scopus 로고    scopus 로고
    • Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: Generation of reactive and redox active o-quinones
    • Penning, T. M., Burczynski, M. E., Hung, C. F., McCoull, K. D., Palackal, N. T., Tsuruda, L. S. (1999) Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones. Chem. Res. Toxicol. 12: 1-18
    • (1999) Chem. Res. Toxicol , vol.12 , pp. 1-18
    • Penning, T.M.1    Burczynski, M.E.2    Hung, C.F.3    McCoull, K.D.4    Palackal, N.T.5    Tsuruda, L.S.6
  • 33
    • 0029958172 scopus 로고    scopus 로고
    • DNA alkaline unwinding assay for monitoring the impact of environmental genotoxins
    • Rao, S. S., Neheli, T. A., Carey, J. H. (1996) DNA alkaline unwinding assay for monitoring the impact of environmental genotoxins. Environ. Toxicol. Water Quality 11: 351-354
    • (1996) Environ. Toxicol. Water Quality , vol.11 , pp. 351-354
    • Rao, S.S.1    Neheli, T.A.2    Carey, J.H.3
  • 34
    • 0038678902 scopus 로고    scopus 로고
    • Benzo(a)pyrene diones are produced by photochemical and enzymatic oxidation and induce concentration-dependent decreases in the proliferative state of human pulmonary epithelial cells
    • Reed, M., Monske, M., Lauer, F., Meserole, S., Born, J., Burchiel, S. (2003) Benzo(a)pyrene diones are produced by photochemical and enzymatic oxidation and induce concentration-dependent decreases in the proliferative state of human pulmonary epithelial cells. J. Toxicol. Environ. Health A 66: 1189-1205
    • (2003) J. Toxicol. Environ. Health A , vol.66 , pp. 1189-1205
    • Reed, M.1    Monske, M.2    Lauer, F.3    Meserole, S.4    Born, J.5    Burchiel, S.6
  • 35
    • 0028189069 scopus 로고
    • Prediction and monitoring of the carcinogenicity of polycyclic aromatic compounds (PACs)
    • Shaw, G. R., Connell, D. W. (1994) Prediction and monitoring of the carcinogenicity of polycyclic aromatic compounds (PACs). Rev. Environ. Contam. Toxicol. 135: 1-62
    • (1994) Rev. Environ. Contam. Toxicol , vol.135 , pp. 1-62
    • Shaw, G.R.1    Connell, D.W.2
  • 36
    • 0023701536 scopus 로고
    • Quantitation of chemically induced damage to DNA of aquatic organisms by alkaline unwinding assay
    • Shugart, L. R. (1988) Quantitation of chemically induced damage to DNA of aquatic organisms by alkaline unwinding assay. Aquatic Toxicol. 13: 43-52
    • (1988) Aquatic Toxicol , vol.13 , pp. 43-52
    • Shugart, L.R.1
  • 37
    • 85051946248 scopus 로고
    • . Biological monitoring: Testing for genotoxicity
    • McCarthy, J. F, Shugart, L. R, ed, Lewis Publishers, Inc, Boca Raton, pp
    • Shugart, L. R. (1990) Chapter 11. Biological monitoring: testing for genotoxicity. In: McCarthy, J. F., Shugart, L. R. (ed.) Biological markers of environmental contaminants. Lewis Publishers, Inc., Boca Raton, pp 205-216
    • (1990) Biological markers of environmental contaminants , pp. 205-216
    • Shugart, L.R.1
  • 38
    • 31744432611 scopus 로고    scopus 로고
    • Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha
    • Sparfel, L., Grevenynghe, J., van Vee, M., Le Aninat, C., Fardel, O. (2006) Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha. Carcinogenesis 27: 656-663
    • (2006) Carcinogenesis , vol.27 , pp. 656-663
    • Sparfel, L.1    Grevenynghe, J.2    van Vee, M.3    Le Aninat, C.4    Fardel, O.5
  • 39
    • 0033410209 scopus 로고    scopus 로고
    • Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide- dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid
    • Sugihara, N., Arakawa, T., Ohnishi, M., Furuno, K. (1999) Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide- dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid. Free Radic. Biol. Med. 27: 1313-1323
    • (1999) Free Radic. Biol. Med , vol.27 , pp. 1313-1323
    • Sugihara, N.1    Arakawa, T.2    Ohnishi, M.3    Furuno, K.4
  • 41
    • 27144432528 scopus 로고    scopus 로고
    • Vegetable and fruit consumption and risk of renal cell carcinoma: Results from the Netherlands cohort study
    • van Dijk, B. A., Schouten, L. J., Kiemeney, L. A., Goldbohm, R. A., van den Brandt, P. A. (2005) Vegetable and fruit consumption and risk of renal cell carcinoma: Results from the Netherlands cohort study. Int. J. Cancer 117: 648-654
    • (2005) Int. J. Cancer , vol.117 , pp. 648-654
    • van Dijk, B.A.1    Schouten, L.J.2    Kiemeney, L.A.3    Goldbohm, R.A.4    van den Brandt, P.A.5
  • 42
    • 0033110348 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons in carcinogenesis
    • Warshawsky, D. (1999) Polycyclic aromatic hydrocarbons in carcinogenesis. Environ. Health Perspect. 107: 317-319
    • (1999) Environ. Health Perspect , vol.107 , pp. 317-319
    • Warshawsky, D.1
  • 43
    • 0016836630 scopus 로고
    • Arylhydrocarbon benzo(a)pyrene hydroxylase in liver from rat of different age, sex and nutritional status
    • Weibel, F. L., Gelboin, H. V. (1975) Arylhydrocarbon benzo(a)pyrene hydroxylase in liver from rat of different age, sex and nutritional status. Biochem. Pharmacol. 24: 1511-1515
    • (1975) Biochem. Pharmacol , vol.24 , pp. 1511-1515
    • Weibel, F.L.1    Gelboin, H.V.2
  • 45
    • 12744276051 scopus 로고    scopus 로고
    • Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells
    • Zheng, P. W., Chiang, L. C., Lin, C. C. (2005) Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells. Life Sci. 76: 1367-1379
    • (2005) Life Sci , vol.76 , pp. 1367-1379
    • Zheng, P.W.1    Chiang, L.C.2    Lin, C.C.3


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