Neurosteroid interactions with synaptic and extrasynaptic GABAA receptors: Regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability

Psychopharmacology

Volumn 230, Issue 2, 2013, Pages 151-188

  Carver, Chase Matthew ^a   Reddy, Doodipala Samba ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

Subunit; Allopregnanolone; Extrasynaptic receptors; GABA; GABAA receptor; Neurosteroid; Phasic inhibition; Tonic inhibition

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA,21 DIHYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; ALFAXALONE; ANDROSTANEDIOL; BENZODIAZEPINE; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; CHLORIDE CHANNEL; EXTRASYNAPTIC RECEPTOR; FINASTERIDE; FLUMAZENIL; FUROSEMIDE; GABOXADOL; GANAXOLONE; GONADOTROPIN; MINAXOLONE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; PREGNENOLONE; PROGESTERONE; RECEPTOR; SYNAPSE RECEPTOR; TAURINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC ION;

4 AMINOBUTYRIC ACID RELEASE; ANXIETY; BEHAVIOR; CONDUCTANCE; EPILEPSY; EXTRACELLULAR FLUID; HUMAN; MEMBRANE POTENTIAL; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE CONDUCTANCE; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVOUS SYSTEM FUNCTION; NONHUMAN; PHASIC INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; REVIEW; SEIZURE; SEIZURE SUSCEPTIBILITY; SLEEP; STRESS; TONIC INHIBITION;

ALLOSTERIC REGULATION; ANDROSTANE-3,17-DIOL; ANIMALS; BRAIN; DESOXYCORTICOSTERONE; HUMANS; NERVE NET; NEURAL INHIBITION; NEURONAL PLASTICITY; NEUROTRANSMITTER AGENTS; PREGNANOLONE; RECEPTORS, GABA-A;

EID: 84891784115     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3276-5     Document Type: Review

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