Pregnenolone sulfate block of GABAA receptors: Mechanism and involvement of a residue in the M2 region of the α subunit

Journal of Physiology

Volumn 532, Issue 3, 2001, Pages 673-684

  Akk, G ^a   Bracamontes, J ^a   Steinbach, J H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; NEUROSTEROID; PREGNENOLONE SULFATE; RECEPTOR SUBUNIT; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2;

ALPHA CHAIN; ANALYSIS; ARTICLE; BINDING SITE; BRAIN; CELL MEMBRANE POTENTIAL; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION CURRENT; MEMBRANE CHANNEL; MEMBRANE CURRENT; MOLECULE; MUTATION; NERVE CELL; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; STEROIDOGENESIS; ASSOCIATION RATE CONSTANT; BINDING AFFINITY; DRUG BINDING SITE; DRUG MECHANISM; DRUG PROTEIN BINDING; MEAN CHANNEL CLOSED TIME; MEAN CHANNEL OPEN TIME; PROTEIN EXPRESSION; TIME TO MAXIMUM PLASMA CONCENTRATION;

BINDING SITES; CELL LINE; ESTRANES; GABA AGONISTS; GABA MODULATORS; GAMMA-AMINOBUTYRIC ACID; HUMANS; ION CHANNEL GATING; KIDNEY; LIGANDS; MEMBRANE POTENTIALS; MUTAGENESIS; NITRILES; PATCH-CLAMP TECHNIQUES; PENTOBARBITAL; PIPERIDINES; PREGNENOLONE; RECEPTORS, GABA-A; TRANSFECTION;

EID: 0035338230     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0673e.x     Document Type: Article

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