Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABAA receptor

Molecular Pharmacology

Volumn 82, Issue 3, 2012, Pages 408-419

  Chen, Zi Wei ^a   Manion, Brad ^a   Townsend, R Reid ^a   Reichert, David E ^b   Covey, Douglas F ^a   Steinbach, Joe Henry ^a   Sieghart, Werner ^c   Fuchs, Karoline ^c   Evers, Alex S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Medical University of Vienna   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

(3ALPHA,5BETA) 6 AZIPREGNANOLONE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; NEUROSTEROID; REAGENT; TERT BUTYLBICYCLOPHOSPHOROTHIOATE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; BETA CHAIN; BINDING SITE; CONCENTRATION RESPONSE; FEASIBILITY STUDY; IC 50; IMMUNOBLOTTING; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; AZIRIDINES; BINDING SITES; BRAIN; CELLS, CULTURED; HUMANS; IMMUNOBLOTTING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUROTRANSMITTER AGENTS; PHOTOAFFINITY LABELS; PREGNANOLONE; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RATS; RECEPTORS, GABA-A;

EID: 84865244600     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.078410     Document Type: Article

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