Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens

European Journal of Medicinal Chemistry

Volumn 43, Issue 1, 2008, Pages 107-113

  Katona, Bryson W ^a   Krishnan, Kathiresan ^a   Cai, Zu Yun ^a   Manion, Brad D ^a   Benz, Ann ^a   Taylor, Amanda ^a   Evers, Alex S ^a   Zorumski, Charles F ^a   Mennerick, Steven ^a   Covey, Douglas F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ent Androgens; GABAA receptors; Neuroactive steroids; Steroid enantiomers

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; ANDROGEN; ANDROSTERONE; CARBONYL DERIVATIVE; ELTANOLONE; ETIOCHOLANOLONE; NEUROSTEROID; SPIRO EPOXIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHLORIDE CURRENT; DRUG POTENCY; DRUG STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; GABAERGIC SYSTEM; NONHUMAN;

ANDROGENS; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CHLORIDE CHANNELS; GABA MODULATORS; LARVA; RATS; RECEPTORS, GABA-A; STEREOISOMERISM; STEROIDS;

EID: 38149081435     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.02.017     Document Type: Article

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