Neurosteroid regulation of GABAA receptors: Focus on the α4 and δ subunits

Pharmacology and Therapeutics

Volumn 116, Issue 1, 2007, Pages 58-76

  Smith, Sheryl S ^a   Shen, Hui ^a   Gong, Qi Hua ^a   Zhou, Xiangping ^a  

^a SUNY Downstate Medical Center   (United States)

Author keywords

Allopregnanolone; Alpha 4; Anxiety; Delta; GABA; GABAA receptor; Hippocampus; Mood; Neurosteroid; Panic; Pregnanolone; Premenstrual dysphoric disorder; Premenstrual syndrome; Puberty; THP

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 3ALPHA DIHYDROPROGESTERONE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; ALCOHOL; BENZODIAZEPINE; CHLORIDE; DIAZEPAM; ELTANOLONE; FINASTERIDE; FLUMAZENIL; GABOXADOL; GANAXOLONE; NEUROSTEROID; OXYTOCIN; PENTOBARBITAL; PREGNENOLONE; PROGESTERONE; PROGESTERONE DERIVATIVE; PROTEIN KINASE C; RECEPTOR SUBUNIT; STEROID; UNCLASSIFIED DRUG; ZOLPIDEM;

ANXIETY DISORDER; CATAMENIAL EPILEPSY; CENTRAL NERVOUS SYSTEM; CHLORIDE CURRENT; CHRONIC DRUG ADMINISTRATION; DISEASE PREDISPOSITION; DRUG POTENCY; DRUG RECEPTOR BINDING; ESTRUS CYCLE; EXPOSURE; GABAERGIC SYSTEM; GENE EXPRESSION REGULATION; HUMAN; IN VITRO STUDY; MOOD DISORDER; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; OVARY CYCLE; PREGNANCY; PREMENSTRUAL DYSPHORIC DISORDER; PRIORITY JOURNAL; PUBERTY; REGULATORY MECHANISM; REVIEW; SEIZURE; STRESS;

ANIMALS; HIPPOCAMPUS; HUMANS; INHIBITORY POSTSYNAPTIC POTENTIALS; KINETICS; PREGNANOLONE; PYRAMIDAL CELLS; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 34548588448     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2007.03.008     Document Type: Review

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