Dehydroepiandrosterone - A neurosteroid

European Journal of Clinical Investigation, Supplement

Volumn 30, Issue 3, 2000, Pages 46-50

  Friess, Elisabeth ^a   Schiffelholz, T ^a   Steckler, T ^a   Steiger, A ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

DHEA; Neurophysiology; Review

Indexed keywords

ANDROGEN; ESTROGEN; HORMONE PRECURSOR; NEUROSTEROID; PRASTERONE; PRASTERONE SULFATE;

ADRENAL GLAND; BEHAVIOR; BRAIN; CONFERENCE PAPER; GLIA CELL; HORMONE ACTION; HUMAN; MEMORY; NEUROPHYSIOLOGY; PRIORITY JOURNAL; SLEEP;

EID: 0034480331     PISSN: 0960135X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2000.0300s3046.x     Document Type: Conference Paper

References (41)

1. Sex differences in the twenty-four hour mean plasma concentrations of Dehydroepiandrosterone (DHA) and Dehydroepiandrosterone Sulfate (DHAS) and the DHA to DHAS ratio in normal adults
2. A genetic component to the variation of dehydroepiandrosterone sulfate
3. Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
4. Dehydroepiandrosterone (DHEA): A fountain of youth?
5. Characterization and measurement of dehydroepiandrosterone sulfate in the rat brain
6. Steroids and their conjugates in the mammalian brain
7. Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: Relation to blood levels and the effects of age
8. Neuroactive steroids
9. Steroid modulation of the chloride ionophore in rat brain: Structure activity requirements, regional dependence and mechanism of action
10. Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor
11. Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-d-aspartate in the rat hippocampus
12. Excitatory effect of DHA, DHAS and pregnenolone sulphate, applied by iontophoresis and pressure, on single neurones in the septo-preoptic area of the guinea pig
13. Anxiolytic activity of an endogenous adrenal steroid
14. Sleep induction by an adrenal steroid in the rat
15. Suppressive effects of dehydroepiandrosterone and 3 beta-methyl-androst-5-en-18-one on attack towards lactating female intruders by castrated male mice. II. Brain neurosteroids
16. Effects of benzodiazepine hypnotics on all-night sleep EEG spectra
17. Neurosteroid pregnenolone induces sleep-EEG changes in man compatible with inverse agonistic GABAA-receptor modulation
18. Pregnenolone enhances EEG delta activity during non-rapid eye movement sleep in the rat, in contrast to midazolam
19. Dehydroepiandrosterone increases rapid-eye-movement sleep and EEG power in the spindle-frequency range
20. High doses of systemic DHEA-sulfate do not affect sleep structure and elicit moderate changes on non-REM sleep EEG in rats
21. The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term potentiation
22. Dehydroepiandrosterone and its sulfate enhance memory retention in mice
23. Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it
24. Disrupted allocentric but preserved egocentric spatial learning in transgenic mice with impaired glucocorticoid receptor function
25. Relationships of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality: A French community-based study
26. Effects of a two week physiological dehydroepiandrosterone (DHEA) substitution on cognitive performance and well-being in healthy elderly women and men
27. A single administration of dehydroepiandrosterone (DHEA) does not enhance memory performance in young healthy adults, but immediately reduces cortisol levels
28. Effects of dehydroepiandrosterone (DHEA) replacement in elderly men on event related potentials, memory and wellbeing
29. Effects of replacement dose of dehydroepiandrosterone in men and woman of advancing age
30. Dehydroepiandrosterone and its sulfated derivate reduce neuronal death and enhance astrocytic differentiation in brain cell cultures
31. Developement and regeneration of the nervous system: A role for neurosteroids
32. Plasma dehydroepiandrosterone sulfate in Alzheimer's disease
33. Serum steroid levels in two old men with Alzheimer's Disease (AD) before, during, and after oral administration of dehydroepiandrosterone (DHEA). Pregnenolone synthesis may become rate-limiting in aging
34. Antiglucocorticoid mechanism of dehydroepiandrosterone (DHEA)
35. Neurosteroids do not regulate proopiomelanocortin-gene expression in pituitary cells
36. Amygdaloid nuclei lesions differentially affect glucocorticoid-induced memory enhancement in an inhibitory avoidance task
37. DHEA concentrations in aging and depression
38. Adrenal androgens and cortisol in major depression
39. Antidepressant and cognition-enhancing effects of DHEA in major depression
40. Dehydroepiandrosterone treatment in depression