GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum

Journal of Neuroscience

Volumn 25, Issue 12, 2005, Pages 3234-3245

  Chiu, Chi Sung ^a,f   Brickley, Stephen ^b   Jensen, Kimmo ^c,d   Southwell, Amber ^a   Mckinney, Sheri ^a   Cull Candy, Stuart ^e   Mody, Istvan ^c   Lester, Henry A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cerebellum; Epilepsy; Flunitrazepam; Inhibition; Tiagabine; Tremor

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID TRANSPORTER 1; 4 AMINOBUTYRIC ACID TRANSPORTER 3; CARRIER PROTEIN; FLUNITRAZEPAM; GLUTAMATE DECARBOXYLASE 65; TIAGABINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; ATAXIA; CAGE; CEREBELLUM; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; GABAERGIC TRANSMISSION; GAIT DISORDER; GRANULE CELL; HIPPOCAMPUS; INTERNEURON; KNOCKOUT MOUSE; LOCOMOTION; MOTOR DYSFUNCTION; MOUSE; NERVOUSNESS; NONHUMAN; OPEN FIELD TEST; PREPULSE INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURKINJE CELL; REARING; ROTAROD TEST; TREMOR;

ANIMALS; ANXIETY; ATAXIA; BEHAVIOR, ANIMAL; BENZODIAZEPINES; BODY TEMPERATURE; BODY WEIGHT; CEREBELLUM; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EXPLORATORY BEHAVIOR; GABA ANTAGONISTS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAIT DISORDERS, NEUROLOGIC; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; INHIBITION (PSYCHOLOGY); ISOENZYMES; MAZE LEARNING; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURONS; PENTYLENETETRAZOLE; PSYCHOMOTOR PERFORMANCE; PYRIDAZINES; RECEPTORS, GABA-A; REFLEX, ACOUSTIC; ROTAROD PERFORMANCE TEST; SEIZURES; SYNAPTOSOMES; TREMOR; VESICULAR INHIBITORY AMINO ACID TRANSPORT PROTEINS;

EID: 16244405559     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3364-04.2005     Document Type: Article

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