Selective antagonism of 5α-reduced neurosteroid effects at GABA A receptors

Molecular Pharmacology

Volumn 65, Issue 5, 2004, Pages 1191-1197

  Mennerick, Steven ^a   He, Yejun ^a,b   Jiang, Xin ^a   Manion, Brad D ^a   Wang, Mingde ^a,c   Shute, Amanda ^a   Benz, Ann ^a   Evers, Alex S ^a   Covey, Douglas F ^a   Zorumski, Charles F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

(3ALPHA,5ALPHA) 17 PHENYLANDROST 16 EN 3 OL; 4 AMINOBUTYRIC ACID A RECEPTOR; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; NEUROSTEROID; STEROID; UNCLASSIFIED DRUG; 17 PHENYLANDROST 16 EN 3 OL; 17-PHENYLANDROST-16-EN-3-OL; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ANDROSTANE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HIPPOCAMPUS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; XENOPUS LAEVIS; ANIMAL; CHEMISTRY; CYTOLOGY; METABOLISM; NERVE CELL; SPRAGUE DAWLEY RAT; SYNTHESIS;

ANDROSTENOLS; ANIMALS; DRUG SYNERGISM; GABA ANTAGONISTS; HIPPOCAMPUS; NEURONS; OOCYTES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STEROIDS; XENOPUS LAEVIS;

EID: 11144354115     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.5.1191     Document Type: Article

References (20)

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