Antagonism of neurosteroid modulation of native γ-aminobutyric acid receptors by (3α,5α)-17-phenylandrost-16-en-3-ol

European Journal of Pharmacology

Volumn 572, Issue 2-3, 2007, Pages 94-101

  Kelley, Stephen P ^a   Alan, Jamie K ^a   O'Buckley, Todd K ^a   Mennerick, Steven ^b   Krishnan, Kathiresan ^b   Covey, Douglas F ^b   Leslie Morrow, A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Native GABA receptor; Neuroactive steroid; Recombinant 1 2 2 receptor; Sedation

Indexed keywords

(3ALPHA,5ALPHA) 17 PHENYLANDROST 16 EN 3 OL; 3ALPHA,21 DIHYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; ANDROGEN; ION CHANNEL; NEUROSTEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CHLORIDE TRANSPORT; CONTROLLED STUDY; DRUG ANTAGONISM; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEDATION; SYNAPTOSOME;

ANDROSTENOLS; ANIMALS; CEREBRAL CORTEX; CHLORIDES; FEMALE; IMMOBILITY RESPONSE, TONIC; INJECTIONS, INTRAVENTRICULAR; MALE; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 34548812043     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.06.028     Document Type: Article

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