Increase of GABAA receptor-mediated tonic inhibition in dentate granule cells after traumatic brain injury

Neurobiology of Disease

Volumn 38, Issue 3, 2010, Pages 464-475

  Mtchedlishvili, Zakaria ^a,b   Lepsveridze, Eka ^c   Xu, Hong ^a   Kharlamov, Elena A ^a,b   Lu, Bo ^a   Kelly, Kevin M ^a,b  

^a ALLEGHENY GENERAL HOSPITAL   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c ILIA STATE UNIVERSITY   (Georgia)

Author keywords

Bicuculline; Dentate granule cells; Diazepam; Furosemide; GABAA receptor; MIPSCs; Synaptic currents; THIP; Tonic currents; Traumatic brain injury

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; BENZODIAZEPINE; DIAZEPAM; FUROSEMIDE; GABOXADOL; RECEPTOR SUBUNIT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 4,5,6,7-TETRAHYDROISOXAZOLO(5,4-C)PYRIDIN-3-OL; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; ISOXAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; GABAERGIC SYSTEM; GRANULE CELL; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TRAUMATIC BRAIN INJURY; WHOLE CELL; ANIMAL; BRAIN INJURY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; IN VITRO STUDY; METABOLISM; NERVE CELL; NERVE CELL INHIBITION; PATCH CLAMP; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE; TEMPERATURE; TIME;

ANIMALS; BRAIN INJURIES; DENTATE GYRUS; DIAZEPAM; FUROSEMIDE; GABA AGONISTS; GABA MODULATORS; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIALS; ISOXAZOLES; MALE; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPSES; TEMPERATURE; TIME FACTORS;

EID: 77952552881     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.03.012     Document Type: Article

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