Pharmacological characterization of a novel cell line expressing human α 4β 3δ GABA A receptors

British Journal of Pharmacology

Volumn 136, Issue 7, 2002, Pages 965-974

  Brown, N ^a   Kerby, J ^a   Bonnert, T P ^a   Whiting, P J ^a   Wafford, Keith A ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Allosteric modulation; Alpha 4 subunit; Anaesthetic; Benzodiazepine; Delta subunit; Desensitization; GABA A receptor; Inhibitory neurotransmission; Neurosteroid

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; 4 PIPERIDINESULFONIC ACID; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; ALPHA4 BETA3 DELTA GAMMA AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; ETOMIDATE; GABOXADOL; LANTHANUM; NEUROSTEROID; PENTOBARBITAL; PICROTOXIN; PROPOFOL; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; ZINC; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ANESTHETIC AGENT; PREGNANE DERIVATIVE; PROTEIN SUBUNIT;

ALLOSTERISM; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DESENSITIZATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SPECIFICITY; GABAERGIC SYSTEM; HUMAN; HUMAN CELL; INHIBITION KINETICS; PATCH CLAMP; PH; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; TISSUE DISTRIBUTION; ANIMAL; BINDING SITE; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FIBROBLAST; KINETICS; METABOLISM; MOUSE; PHYSIOLOGY;

ALLOSTERIC REGULATION; ANESTHETICS; ANIMAL; BENZODIAZEPINES; BINDING SITES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GABA AGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HUMAN; KINETICS; MICE; PATCH-CLAMP TECHNIQUES; PREGNANES; PROTEIN SUBUNITS; RECEPTORS, GABA-A; ANIMALS; HUMANS;

EID: 0036024231     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704795     Document Type: Article

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