Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABA(A) receptor

Journal of Neuroscience

Volumn 17, Issue 2, 1997, Pages 625-634

  Ueno, Shinya ^a,c   Bracamontes, John ^a   Zorumski, Chuck ^a   Weiss, David S ^b   Steinbach, Joe Henry ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

allosteric inhibitor; anesthetics; bicuculline; GABA; GABA(A) receptor; inverse agonist; neurosteroids

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID RECEPTOR; ALFAXALONE; BICUCULLINE; ION CHANNEL; PENTOBARBITAL;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; GABAERGIC TRANSMISSION; KINETICS; NONHUMAN; PRIORITY JOURNAL; RAT; STEROID BINDING;

EID: 0031011984     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-02-00625.1997     Document Type: Article

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