Neurosteroid prolongs GABA(A) channel deactivation by altering kinetics of desensitized states

Journal of Neuroscience

Volumn 17, Issue 11, 1997, Pages 4022-4031

  Zhu, Wei Jian ^a   Vicini, Stefano ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

desensitization; GABA(A) receptor; IPSC; patch clamp; taurine; THDOC

Indexed keywords

GABAERGIC RECEPTOR AFFECTING AGENT; NEUROSTEROID; TAURINE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ANXIOLYTIC AGENT; DEOXYCORTICOSTERONE; DRUG DERIVATIVE; TETRAHYDRODEOXYCORTICOSTERONE;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DESENSITIZATION; NEUROPROTECTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY; VOLTAGE CLAMP; AGE; ANIMAL; CEREBELLUM; CHANNEL GATING; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GROWTH, DEVELOPMENT AND AGING; KINETICS; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT;

AGE FACTORS; ANIMALS; ANTI-ANXIETY AGENTS; CEREBELLUM; DESOXYCORTICOSTERONE; GAMMA-AMINOBUTYRIC ACID; ION CHANNEL GATING; KINETICS; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SENSITIVITY AND SPECIFICITY; TAURINE;

EID: 0031156830     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-11-04022.1997     Document Type: Article

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