메뉴 건너뛰기




Volumn 50, Issue 8, 2006, Pages 1059-1071

Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy

Author keywords

Absence seizures; Allopregnanolone; Ganaxolone; Neurosteroids; Pregnenolone sulphate; Primary somatosensory cortex; Thalamus; WAG Rij rat

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; GANAXOLONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROSTEROID; PREGNENOLONE SULFATE;

EID: 33744549505     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.02.011     Document Type: Article
Times cited : (45)

References (116)
  • 1
    • 0002233319 scopus 로고    scopus 로고
    • Epilepsy
    • Martin D.L., and Olsen R.W. (Eds), Lippincot Williams & Wilkins, Philadelphia
    • Avoli M. Epilepsy. In: Martin D.L., and Olsen R.W. (Eds). GABA in the Nervous System: The View at Fifty Years (2000), Lippincot Williams & Wilkins, Philadelphia 293-316
    • (2000) GABA in the Nervous System: The View at Fifty Years , pp. 293-316
    • Avoli, M.1
  • 2
    • 0034307713 scopus 로고    scopus 로고
    • Cortical feedback controls the frequency and synchrony of oscillations in the visual thalamus
    • Bal T., Debay D., and Destexhe A. Cortical feedback controls the frequency and synchrony of oscillations in the visual thalamus. Journal of Neuroscience 20 (2000) 7478-7488
    • (2000) Journal of Neuroscience , vol.20 , pp. 7478-7488
    • Bal, T.1    Debay, D.2    Destexhe, A.3
  • 3
    • 0026459644 scopus 로고
    • Involvement of excitatory amino acid mechanisms in gamma-hydroxybutyrate model of generalized absence seizures in rats
    • Banerjee P.K., and Snead III O.C. Involvement of excitatory amino acid mechanisms in gamma-hydroxybutyrate model of generalized absence seizures in rats. Neuropharmacology 31 (1992) 1009-1019
    • (1992) Neuropharmacology , vol.31 , pp. 1009-1019
    • Banerjee, P.K.1    Snead III, O.C.2
  • 4
    • 0028899954 scopus 로고
    • Thalamic NMDA receptors in the gamma-hydroxybutyrate model of absence seizures: a cerebral microinjection study in rats
    • Banerjee P.K., and Snead III O.C. Thalamic NMDA receptors in the gamma-hydroxybutyrate model of absence seizures: a cerebral microinjection study in rats. Neuropharmacology 34 (1995) 43-53
    • (1995) Neuropharmacology , vol.34 , pp. 43-53
    • Banerjee, P.K.1    Snead III, O.C.2
  • 5
    • 0030630595 scopus 로고    scopus 로고
    • Neurosteroids: of the nervous system, by the nervous system, for the nervous system
    • Baulieu E.E. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Progress in Hormone Research 52 (1997) 1-33
    • (1997) Recent Progress in Hormone Research , vol.52 , pp. 1-33
    • Baulieu, E.E.1
  • 6
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: a novel function of the brain
    • Baulieu E.E. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 23 (1998) 963-987
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 963-987
    • Baulieu, E.E.1
  • 9
    • 0024321145 scopus 로고
    • Anticonvulsant profile of the progesterone metabolite 5alpha-pregnan-3alpha-ol-20-one
    • Belelli D., Bolger M.B., and Gee K.W. Anticonvulsant profile of the progesterone metabolite 5alpha-pregnan-3alpha-ol-20-one. European Journal Pharmacology 166 (1989) 325-329
    • (1989) European Journal Pharmacology , vol.166 , pp. 325-329
    • Belelli, D.1    Bolger, M.B.2    Gee, K.W.3
  • 10
    • 0025161662 scopus 로고
    • Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex
    • Belelli D., Lan N.C., and Gee K.W. Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex. Neuroscience and Biobehavioral Review 14 (1990) 315-322
    • (1990) Neuroscience and Biobehavioral Review , vol.14 , pp. 315-322
    • Belelli, D.1    Lan, N.C.2    Gee, K.W.3
  • 11
    • 0030010448 scopus 로고    scopus 로고
    • Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors
    • Bergeron R., de Montigny C., and Debonnel G. Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. Journal of Neuroscience 16 (1996) 1193-1202
    • (1996) Journal of Neuroscience , vol.16 , pp. 1193-1202
    • Bergeron, R.1    de Montigny, C.2    Debonnel, G.3
  • 13
    • 0034234533 scopus 로고    scopus 로고
    • Corticothalamic inputs control the pattern of activity generated in thalamocortical networks
    • Blumenfeld H., and McCormick D.A. Corticothalamic inputs control the pattern of activity generated in thalamocortical networks. Journal of Neuroscience 20 (2000) 5153-5162
    • (2000) Journal of Neuroscience , vol.20 , pp. 5153-5162
    • Blumenfeld, H.1    McCormick, D.A.2
  • 14
  • 19
    • 0029069095 scopus 로고
    • Effects of the GABA-uptake inhibitor tiagabine on electroencephalogram, spike-wave discharges and behaviour of rats
    • Coenen A.M., Blezer E., and Van Luijtelaar E.L. Effects of the GABA-uptake inhibitor tiagabine on electroencephalogram, spike-wave discharges and behaviour of rats. Epilepsy Research 21 (1995) 89-94
    • (1995) Epilepsy Research , vol.21 , pp. 89-94
    • Coenen, A.M.1    Blezer, E.2    Van Luijtelaar, E.L.3
  • 21
    • 0024502037 scopus 로고
    • Effects of diazepam and two beta-carbolines on epileptic activity and on EEG and behavior in rats with absence seizures
    • Coenen A.M., and van Luijtelaar E.L. Effects of diazepam and two beta-carbolines on epileptic activity and on EEG and behavior in rats with absence seizures. Pharmacology Biochemistry and Behaviour 32 (1989) 27-35
    • (1989) Pharmacology Biochemistry and Behaviour , vol.32 , pp. 27-35
    • Coenen, A.M.1    van Luijtelaar, E.L.2
  • 22
    • 0345256499 scopus 로고    scopus 로고
    • Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats
    • Coenen A.M., and Van Luijtelaar E.L. Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats. Behavior Genetics 33 (2003) 635-655
    • (2003) Behavior Genetics , vol.33 , pp. 635-655
    • Coenen, A.M.1    Van Luijtelaar, E.L.2
  • 23
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: biosynthesis and function of these novel neuromodulators
    • Compagnone N.A., and Mellon S.H. Neurosteroids: biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21 (2000) 1-56
    • (2000) Frontiers in Neuroendocrinology , vol.21 , pp. 1-56
    • Compagnone, N.A.1    Mellon, S.H.2
  • 25
    • 0025924527 scopus 로고
    • B receptors in excitation and inhibition of thalamocortical cells
    • B receptors in excitation and inhibition of thalamocortical cells. Trends in Neuroscience 14 (1991) 16-21
    • (1991) Trends in Neuroscience , vol.14 , pp. 16-21
    • Crunelli, V.1    Leresche, N.2
  • 28
    • 0035009415 scopus 로고    scopus 로고
    • The new generation of GABA enhancers. Potential in the treatment of epilepsy
    • Czuczwar S.J., and Patsalos P.N. The new generation of GABA enhancers. Potential in the treatment of epilepsy. CNS Drugs 15 (2001) 339-350
    • (2001) CNS Drugs , vol.15 , pp. 339-350
    • Czuczwar, S.J.1    Patsalos, P.N.2
  • 31
    • 0026757458 scopus 로고
    • Excitatory neurotransmitters in the lateral habenula and peduncolopontine nucleus of rat modulate limbic seizures induced by pilocarpine
    • De Sarro G.B., Meldrum B.S., De Sarro A., and Patel S. Excitatory neurotransmitters in the lateral habenula and peduncolopontine nucleus of rat modulate limbic seizures induced by pilocarpine. Brain Research 591 (1992) 209-222
    • (1992) Brain Research , vol.591 , pp. 209-222
    • De Sarro, G.B.1    Meldrum, B.S.2    De Sarro, A.3    Patel, S.4
  • 36
    • 0032983002 scopus 로고    scopus 로고
    • Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders
    • Gasior M., Carter R.B., and Witkin J.M. Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders. Trends in Pharmacological Science 20 (1999) 107-112
    • (1999) Trends in Pharmacological Science , vol.20 , pp. 107-112
    • Gasior, M.1    Carter, R.B.2    Witkin, J.M.3
  • 37
    • 0034101871 scopus 로고    scopus 로고
    • Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate
    • Gasior M., Ungard J.T., Beekman M., Carter R.B., and Witkin J.M. Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate. Neuropharmacology 27 (2000) 1184-1196
    • (2000) Neuropharmacology , vol.27 , pp. 1184-1196
    • Gasior, M.1    Ungard, J.T.2    Beekman, M.3    Carter, R.B.4    Witkin, J.M.5
  • 38
    • 0024145170 scopus 로고
    • Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore
    • Gee K.W. Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore. Molecular Neurobiology 2 (1988) 291-317
    • (1988) Molecular Neurobiology , vol.2 , pp. 291-317
    • Gee, K.W.1
  • 39
    • 0023681634 scopus 로고
    • Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action
    • Gee K.W., Bolger M.B., Brinton R.E., Coirini H., and McEwen B.S. Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action. Journal of Pharmacology and Experimental Therapeutics 246 (1988) 803-812
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.246 , pp. 803-812
    • Gee, K.W.1    Bolger, M.B.2    Brinton, R.E.3    Coirini, H.4    McEwen, B.S.5
  • 40
    • 0028801074 scopus 로고
    • A receptor complex: the pharmacological properties and therapeutic potential of epalons
    • A receptor complex: the pharmacological properties and therapeutic potential of epalons. Critical Reviews in Neurobiology 9 (1995) 207-227
    • (1995) Critical Reviews in Neurobiology , vol.9 , pp. 207-227
    • Gee, K.W.1    McCauley, L.D.2    Lan, N.C.3
  • 41
    • 0023911219 scopus 로고
    • Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy
    • Gloor P., and Fariello R.G. Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy. Trends in Neuroscience 11 (1988) 63-68
    • (1988) Trends in Neuroscience , vol.11 , pp. 63-68
    • Gloor, P.1    Fariello, R.G.2
  • 45
    • 0032975421 scopus 로고    scopus 로고
    • Progesterone therapy in women with epilepsy: a 3-year follow-up
    • Herzog A.G. Progesterone therapy in women with epilepsy: a 3-year follow-up. Neurology 10 (1999) 1917-1918
    • (1999) Neurology , vol.10 , pp. 1917-1918
    • Herzog, A.G.1
  • 46
    • 0030866438 scopus 로고    scopus 로고
    • Three patterns of catamenial epilepsy
    • Herzog A.G., Klein P., and Ransil B.J. Three patterns of catamenial epilepsy. Epilepsia 38 (1997) 1082-1088
    • (1997) Epilepsia , vol.38 , pp. 1082-1088
    • Herzog, A.G.1    Klein, P.2    Ransil, B.J.3
  • 47
    • 20044363806 scopus 로고    scopus 로고
    • The effects of the neurosteroids: pregnenolone, progesterone and dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors
    • Horishita T., Minami K., Uezono Y., Shiraishi M., Ogata J., Okamoto T., Terada T., and Sata T. The effects of the neurosteroids: pregnenolone, progesterone and dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors. Naunyn Schmiedeberg's Archives of Pharmacology 371 (2005) 221-228
    • (2005) Naunyn Schmiedeberg's Archives of Pharmacology , vol.371 , pp. 221-228
    • Horishita, T.1    Minami, K.2    Uezono, Y.3    Shiraishi, M.4    Ogata, J.5    Okamoto, T.6    Terada, T.7    Sata, T.8
  • 48
    • 0030985886 scopus 로고    scopus 로고
    • Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures
    • Hosford D.A., Wang Y., and Cao Z. Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures. Epilepsy Research 27 (1997) 55-65
    • (1997) Epilepsy Research , vol.27 , pp. 55-65
    • Hosford, D.A.1    Wang, Y.2    Cao, Z.3
  • 49
    • 0028174189 scopus 로고
    • B mediated inhibition in thalamic relay neurons through effects in nucleus reticularis
    • B mediated inhibition in thalamic relay neurons through effects in nucleus reticularis. Journal of Physiology 71 (1994) 2576-2581
    • (1994) Journal of Physiology , vol.71 , pp. 2576-2581
    • Huguenard, J.R.1    Prince, D.A.2
  • 50
    • 0033593590 scopus 로고    scopus 로고
    • Reciprocal inhibitory connections and network synchrony in the mammalian thalamus
    • Huntsman M.M., Porcello D.M., Homanics G.E., DeLorey T.M., and Huguenard J.R. Reciprocal inhibitory connections and network synchrony in the mammalian thalamus. Science 283 (1999) 541-543
    • (1999) Science , vol.283 , pp. 541-543
    • Huntsman, M.M.1    Porcello, D.M.2    Homanics, G.E.3    DeLorey, T.M.4    Huguenard, J.R.5
  • 52
    • 0030873997 scopus 로고    scopus 로고
    • Functional dynamics of GABAergic inhibition in the thalamus
    • Kim U., Sanchez-Vives M.V., and McCormick D.A. Functional dynamics of GABAergic inhibition in the thalamus. Science 278 (1997) 130-134
    • (1997) Science , vol.278 , pp. 130-134
    • Kim, U.1    Sanchez-Vives, M.V.2    McCormick, D.A.3
  • 53
    • 0026611822 scopus 로고
    • GABA receptors in rats with spontaneous generalized nonconvulsive epilepsy
    • Knight A.R., and Bowery N.G. GABA receptors in rats with spontaneous generalized nonconvulsive epilepsy. Journal of Neural Transmission 35 Suppl. (1992) 189-196
    • (1992) Journal of Neural Transmission , vol.35 , Issue.SUPPL , pp. 189-196
    • Knight, A.R.1    Bowery, N.G.2
  • 56
    • 0028149787 scopus 로고
    • Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation
    • Kokate T.G., Svensson B.E., and Rogawski M.A. Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. Journal of Pharmacology and Experimental Therapeutics 270 (1994) 1223-1229
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 1223-1229
    • Kokate, T.G.1    Svensson, B.E.2    Rogawski, M.A.3
  • 59
    • 0023608657 scopus 로고
    • The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex
    • Landgren S., Aasly J., Backstrom T., Dubrovsky B., and Danielsson E. The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex. Acta Physiologica Scandinavia 131 (1987) 33-42
    • (1987) Acta Physiologica Scandinavia , vol.131 , pp. 33-42
    • Landgren, S.1    Aasly, J.2    Backstrom, T.3    Dubrovsky, B.4    Danielsson, E.5
  • 61
    • 0025847753 scopus 로고
    • The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices
    • Loscher W., and Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices. Epilepsy Research 9 (1991) 1-10
    • (1991) Epilepsy Research , vol.9 , pp. 1-10
    • Loscher, W.1    Nolting, B.2
  • 62
    • 0023897574 scopus 로고
    • Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
    • Loscher W., and Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Research 2 (1988) 145-181
    • (1988) Epilepsy Research , vol.2 , pp. 145-181
    • Loscher, W.1    Schmidt, D.2
  • 63
    • 0028220347 scopus 로고
    • Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?
    • Loscher W., and Schmidt D. Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?. Epilepsy Research 17 (1994) 95-134
    • (1994) Epilepsy Research , vol.17 , pp. 95-134
    • Loscher, W.1    Schmidt, D.2
  • 66
    • 0026509649 scopus 로고
    • A receptor. Mechanism of action and physiological significance
    • A receptor. Mechanism of action and physiological significance. Progress in Neurobiology 38 (1992) 379-395
    • (1992) Progress in Neurobiology , vol.38 , pp. 379-395
    • Majewska, M.D.1
  • 67
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • Majewska M.D., Harrison N.L., Schwartz R.D., Barker J.L., and Paul S.M. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science 23 (1986) 1004-1007
    • (1986) Science , vol.23 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 68
    • 0023114555 scopus 로고
    • Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
    • Majewska M.D., and Schwartz R.D. Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?. Brain Research 24 (1987) 355-360
    • (1987) Brain Research , vol.24 , pp. 355-360
    • Majewska, M.D.1    Schwartz, R.D.2
  • 69
    • 0034893038 scopus 로고    scopus 로고
    • Subunit-specific modulation of glycine receptors by neurosteroids
    • Maksay G.B., Laube H., and Betz H. Subunit-specific modulation of glycine receptors by neurosteroids. Neuropharmacology 41 (2001) 369-376
    • (2001) Neuropharmacology , vol.41 , pp. 369-376
    • Maksay, G.B.1    Laube, H.2    Betz, H.3
  • 70
    • 0036185532 scopus 로고    scopus 로고
    • Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids
    • Malayev A., Gibbs T.T., and Farb D.H. Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. British Journal of Pharmacology 135 (2002) 901-909
    • (2002) British Journal of Pharmacology , vol.135 , pp. 901-909
    • Malayev, A.1    Gibbs, T.T.2    Farb, D.H.3
  • 71
    • 0345549501 scopus 로고    scopus 로고
    • Cortical area specific block of genetically determined absence seizures by ethosuximide
    • Manning J.-P.A., Richards D.A., Leresche N., Crunelli V., and Bowery N.G. Cortical area specific block of genetically determined absence seizures by ethosuximide. Neuroscience 123 (2004) 5-9
    • (2004) Neuroscience , vol.123 , pp. 5-9
    • Manning, J.-P.A.1    Richards, D.A.2    Leresche, N.3    Crunelli, V.4    Bowery, N.G.5
  • 74
    • 0028003285 scopus 로고
    • Neurosteroids: biochemistry, modes of action, and clinical relevance
    • Mellon S.H. Neurosteroids: biochemistry, modes of action, and clinical relevance. Journal of Clinical Endocrinological Metabolism 78 (1994) 1003-1008
    • (1994) Journal of Clinical Endocrinological Metabolism , vol.78 , pp. 1003-1008
    • Mellon, S.H.1
  • 76
    • 0032956181 scopus 로고    scopus 로고
    • Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan A., Do-Rego J.L., Beaujean D., Luu-The V., Pelletier G., and Vaudry H. Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacological Reviews 51 (1999) 63-81
    • (1999) Pharmacological Reviews , vol.51 , pp. 63-81
    • Mensah-Nyagan, A.1    Do-Rego, J.L.2    Beaujean, D.3    Luu-The, V.4    Pelletier, G.5    Vaudry, H.6
  • 77
    • 0032846421 scopus 로고    scopus 로고
    • Ganaxolone: a novel positive allosteric modulator of the GABA(A) receptor complex for the treatment of epilepsy
    • Monaghan E.P., McAuley J.W., and Data J.L. Ganaxolone: a novel positive allosteric modulator of the GABA(A) receptor complex for the treatment of epilepsy. Expert Opinion on Investigational Drugs 8 (1999) 1663-1671
    • (1999) Expert Opinion on Investigational Drugs , vol.8 , pp. 1663-1671
    • Monaghan, E.P.1    McAuley, J.W.2    Data, J.L.3
  • 79
    • 0025166305 scopus 로고
    • Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites
    • Morrow A.L., Pace J.R., Purdy R.H., and Paul S.M. Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. Molecular Pharmacology 37 (1990) 263-270
    • (1990) Molecular Pharmacology , vol.37 , pp. 263-270
    • Morrow, A.L.1    Pace, J.R.2    Purdy, R.H.3    Paul, S.M.4
  • 80
    • 0023548049 scopus 로고
    • Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency
    • Morrow A.L., Suzdak P.D., and Paul S.M. Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency. European Journal of Pharmacology 142 (1987) 483-485
    • (1987) European Journal of Pharmacology , vol.142 , pp. 483-485
    • Morrow, A.L.1    Suzdak, P.D.2    Paul, S.M.3
  • 81
    • 0035577640 scopus 로고    scopus 로고
    • Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy
    • Mtchedlishvili Z., Bertram E.H., and Kapur J. Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy. Journal of Physiology 1 (2001) 453-465
    • (2001) Journal of Physiology , vol.1 , pp. 453-465
    • Mtchedlishvili, Z.1    Bertram, E.H.2    Kapur, J.3
  • 82
    • 0021685459 scopus 로고
    • Isolating single genes of the inherited epilepsies
    • Noebels J.L. Isolating single genes of the inherited epilepsies. Annals of Neurology 16 (1984) 18-21
    • (1984) Annals of Neurology , vol.16 , pp. 18-21
    • Noebels, J.L.1
  • 83
    • 0022565567 scopus 로고
    • Mutational analysis of inherited epilepsies
    • Noebels J.L. Mutational analysis of inherited epilepsies. Advances in Neurology 44 (1986) 97-113
    • (1986) Advances in Neurology , vol.44 , pp. 97-113
    • Noebels, J.L.1
  • 84
    • 0002054212 scopus 로고    scopus 로고
    • Absence epilepsies
    • Engel J., and Pedley T.A. (Eds), Lippincott-Raven Publishers, Philadelphia
    • Panayiotopoulos C. Absence epilepsies. In: Engel J., and Pedley T.A. (Eds). Epilepsy: A Comprehensive Textbook (1997), Lippincott-Raven Publishers, Philadelphia 2327-2346
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 2327-2346
    • Panayiotopoulos, C.1
  • 86
    • 0026773194 scopus 로고
    • Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: a classical crossbreeding study
    • Peeters B.W., Kerbush J.M., Coenen A.M., Vossen J.M., and van Luijtelaar E.L. Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: a classical crossbreeding study. Behavior Genetics 22 (1992) 361-368
    • (1992) Behavior Genetics , vol.22 , pp. 361-368
    • Peeters, B.W.1    Kerbush, J.M.2    Coenen, A.M.3    Vossen, J.M.4    van Luijtelaar, E.L.5
  • 87
    • 0028331809 scopus 로고
    • Interactions between NMDA and nonNMDA receptors in nonconvulsive epilepsy in the WAG/Rij inbred strain
    • Peeters B.W., Ramakers G.M., Ellenbroek B.A., Vossen J.M., and Coenen A.M. Interactions between NMDA and nonNMDA receptors in nonconvulsive epilepsy in the WAG/Rij inbred strain. Brain Research Bulletin 33 (1994) 715-718
    • (1994) Brain Research Bulletin , vol.33 , pp. 715-718
    • Peeters, B.W.1    Ramakers, G.M.2    Ellenbroek, B.A.3    Vossen, J.M.4    Coenen, A.M.5
  • 88
    • 0024474236 scopus 로고
    • Effects of GABA-ergic agents on spontaneous non-convulsive epilepsy, EEG and behaviour, in the WAG/Rij inbred strain of rats
    • Peeters B.W., van Rijn C.M., Vossen J.M., and Coenen A.M. Effects of GABA-ergic agents on spontaneous non-convulsive epilepsy, EEG and behaviour, in the WAG/Rij inbred strain of rats. Life Sciences 45 (1989) 1171-1176
    • (1989) Life Sciences , vol.45 , pp. 1171-1176
    • Peeters, B.W.1    van Rijn, C.M.2    Vossen, J.M.3    Coenen, A.M.4
  • 89
    • 0025146435 scopus 로고
    • Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats
    • Peeters B.W., van Rijn C.M., Vossen J.M., and Coenen A.M. Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats. Life Sciences 47 (1990) 523-529
    • (1990) Life Sciences , vol.47 , pp. 523-529
    • Peeters, B.W.1    van Rijn, C.M.2    Vossen, J.M.3    Coenen, A.M.4
  • 91
    • 3543099220 scopus 로고    scopus 로고
    • The thalamic reticular nucleus: structure, function and concept
    • Pinault D. The thalamic reticular nucleus: structure, function and concept. Brain Research: Brain Research Reviews 46 (2004) 1-31
    • (2004) Brain Research: Brain Research Reviews , vol.46 , pp. 1-31
    • Pinault, D.1
  • 92
    • 0025868506 scopus 로고
    • CNQX, a new non-NMDA receptor antagonist, reduces spike wave discharges in the WAG/Rij rat model of absence epilepsy
    • Ramakers G.M., Peeters B.W., Vossen J.M., and Coenen A.M. CNQX, a new non-NMDA receptor antagonist, reduces spike wave discharges in the WAG/Rij rat model of absence epilepsy. Epilepsy Research 9 (1991) 127-131
    • (1991) Epilepsy Research , vol.9 , pp. 127-131
    • Ramakers, G.M.1    Peeters, B.W.2    Vossen, J.M.3    Coenen, A.M.4
  • 93
    • 3142777130 scopus 로고    scopus 로고
    • Pharmacology of endogenous neuroactive steroids
    • Reddy D.S. Pharmacology of endogenous neuroactive steroids. Critical Reviews in Neurobiology 15 (2003) 197-234
    • (2003) Critical Reviews in Neurobiology , vol.15 , pp. 197-234
    • Reddy, D.S.1
  • 94
    • 0035057345 scopus 로고    scopus 로고
    • Neurosteroid withdrawal model of perimenstrual catamenial epilepsy
    • Reddy D.S., Kim H.Y., and Rogawski M.A. Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. Epilepsia 42 (2001) 328-336
    • (2001) Epilepsia , vol.42 , pp. 328-336
    • Reddy, D.S.1    Kim, H.Y.2    Rogawski, M.A.3
  • 95
    • 0033644935 scopus 로고    scopus 로고
    • Development of neurosteroid-based novel psychotropic drugs
    • Reddy D.S., and Kulkarni S.K. Development of neurosteroid-based novel psychotropic drugs. Progress in Medicinal Chemistry 37 (2000) 135-175
    • (2000) Progress in Medicinal Chemistry , vol.37 , pp. 135-175
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 96
    • 0035060229 scopus 로고    scopus 로고
    • Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy
    • Reddy D.S., and Rogawski M.A. Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia 42 (2001) 337-344
    • (2001) Epilepsia , vol.42 , pp. 337-344
    • Reddy, D.S.1    Rogawski, M.A.2
  • 98
    • 0037371087 scopus 로고    scopus 로고
    • Progesterone, neurosteroids, and the hormonal basis of catamenial. epilepsy
    • Rogawski M.A. Progesterone, neurosteroids, and the hormonal basis of catamenial. epilepsy. Annals of Neurology 53 (2003) 288-291
    • (2003) Annals of Neurology , vol.53 , pp. 288-291
    • Rogawski, M.A.1
  • 99
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives
    • Rupprecht R., and Holsboer F. Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives. Trends in Neuroscience 22 (1999) 410-416
    • (1999) Trends in Neuroscience , vol.22 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 100
    • 1642397435 scopus 로고    scopus 로고
    • Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy
    • Russo E., Costanti A., Ferreri G., Citrato R., and De Sarro G. Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy. Neuropharmacology 46 (2004) 865-878
    • (2004) Neuropharmacology , vol.46 , pp. 865-878
    • Russo, E.1    Costanti, A.2    Ferreri, G.3    Citrato, R.4    De Sarro, G.5
  • 101
    • 0031878517 scopus 로고    scopus 로고
    • Relations between cortical and thalamic cellular activities during absence seizures in rats
    • Seidenbecher T., Staak R., and Pape H.C. Relations between cortical and thalamic cellular activities during absence seizures in rats. European Journal of Neuroscience 10 (1998) 1103-1112
    • (1998) European Journal of Neuroscience , vol.10 , pp. 1103-1112
    • Seidenbecher, T.1    Staak, R.2    Pape, H.C.3
  • 102
    • 0036231790 scopus 로고    scopus 로고
    • Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior
    • Smith S.S. Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior. Steroids 67 (2002) 519-528
    • (2002) Steroids , vol.67 , pp. 519-528
    • Smith, S.S.1
  • 103
    • 0028896579 scopus 로고
    • Basic mechanisms of generalized absence seizures
    • Snead O.C. Basic mechanisms of generalized absence seizures. Annals of Neurology 37 (1995) 146-157
    • (1995) Annals of Neurology , vol.37 , pp. 146-157
    • Snead, O.C.1
  • 104
    • 0031722019 scopus 로고    scopus 로고
    • Ganaxolone, a selective, high-affinity steroid modulator of the gamma-aminobutyric acid-A receptor, exacerbates seizures in animal models of absence
    • Snead O.C. Ganaxolone, a selective, high-affinity steroid modulator of the gamma-aminobutyric acid-A receptor, exacerbates seizures in animal models of absence. Annals of Neurology 44 (1998) 688-691
    • (1998) Annals of Neurology , vol.44 , pp. 688-691
    • Snead, O.C.1
  • 106
    • 0035866054 scopus 로고    scopus 로고
    • B receptors to thalamic neuronal activity during spontaneous absence seizures in rats
    • B receptors to thalamic neuronal activity during spontaneous absence seizures in rats. Journal of Neuroscience 21 (2001) 1378-1384
    • (2001) Journal of Neuroscience , vol.21 , pp. 1378-1384
    • Staak, R.1    Pape, H.C.2
  • 107
    • 0035957405 scopus 로고    scopus 로고
    • The GABAergic reticular nucleus: a preferential target of corticothalamic projections
    • Steriade M. The GABAergic reticular nucleus: a preferential target of corticothalamic projections. Proceeding of the National Academy of Sciences USA 98 (2001) 3625-3627
    • (2001) Proceeding of the National Academy of Sciences USA , vol.98 , pp. 3625-3627
    • Steriade, M.1
  • 108
    • 0031732075 scopus 로고    scopus 로고
    • Spike-wave complexes and fast components of cortically generated seizures: I. Role of neocortex and thalamus
    • Steriade M., and Contreras D. Spike-wave complexes and fast components of cortically generated seizures: I. Role of neocortex and thalamus. Journal of Neurophysiology 80 (1998) 1439-1455
    • (1998) Journal of Neurophysiology , vol.80 , pp. 1439-1455
    • Steriade, M.1    Contreras, D.2
  • 109
    • 2442506898 scopus 로고    scopus 로고
    • Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits
    • Ueno S., Tsutsui M., Toyohira Y., Minami K., and Yanagihara N. Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits. FEBS Letters 21 (2004) 213-217
    • (2004) FEBS Letters , vol.21 , pp. 213-217
    • Ueno, S.1    Tsutsui, M.2    Toyohira, Y.3    Minami, K.4    Yanagihara, N.5
  • 110
    • 0028890399 scopus 로고
    • Role of L-type calcium channel modulation in non convulsive epilepsy in rats
    • Van Luijtelaar E.L., Ates N., and Coenen A.M. Role of L-type calcium channel modulation in non convulsive epilepsy in rats. Epilepsia 36 (1995) 86-92
    • (1995) Epilepsia , vol.36 , pp. 86-92
    • Van Luijtelaar, E.L.1    Ates, N.2    Coenen, A.M.3
  • 111
    • 0034881616 scopus 로고    scopus 로고
    • The ovarian hormones and absence epilepsy: a long-term EEG study and pharmacological effects in a genetic absence epilepsy model
    • Van Luijtelaar G., Budziszewska B., Jaworska-Feil L., Ellis J., Coenen A., and Lason W. The ovarian hormones and absence epilepsy: a long-term EEG study and pharmacological effects in a genetic absence epilepsy model. Epilepsy Research 46 (2001) 225-239
    • (2001) Epilepsy Research , vol.46 , pp. 225-239
    • Van Luijtelaar, G.1    Budziszewska, B.2    Jaworska-Feil, L.3    Ellis, J.4    Coenen, A.5    Lason, W.6
  • 112
    • 0142042971 scopus 로고    scopus 로고
    • Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy
    • Van Luijtelaar G., Budziszewska B., Tetich M., and Lason W. Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy. Pharmacology, Biochemistry, and Behavior 75 (2003) 889-894
    • (2003) Pharmacology, Biochemistry, and Behavior , vol.75 , pp. 889-894
    • Van Luijtelaar, G.1    Budziszewska, B.2    Tetich, M.3    Lason, W.4
  • 113
    • 0026611825 scopus 로고
    • Cortical and thalamic lesions in rats with genetic absence epilepsy
    • Vergnes M., and Marescaux C. Cortical and thalamic lesions in rats with genetic absence epilepsy. Journal of Neural Transmission 35 Suppl. (1992) 71-83
    • (1992) Journal of Neural Transmission , vol.35 , Issue.SUPPL , pp. 71-83
    • Vergnes, M.1    Marescaux, C.2
  • 114
    • 0038077053 scopus 로고    scopus 로고
    • The GABAA receptor: subunit dependent functions and absence seizures
    • Wang C.G.T., and Snead III O.C. The GABAA receptor: subunit dependent functions and absence seizures. Epilepsy Currents 1 (2001) 1-5
    • (2001) Epilepsy Currents , vol.1 , pp. 1-5
    • Wang, C.G.T.1    Snead III, O.C.2
  • 115
    • 0026612363 scopus 로고
    • The distribution of 13 GABA A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • Wisden W., Laurie D.J., Monyer H., and Seeburg P.H. The distribution of 13 GABA A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. Journal of Neuroscience 2 (1992) 1040-1062
    • (1992) Journal of Neuroscience , vol.2 , pp. 1040-1062
    • Wisden, W.1    Laurie, D.J.2    Monyer, H.3    Seeburg, P.H.4
  • 116
    • 0025995802 scopus 로고
    • Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-d-aspartate receptor
    • Wu F.S., Gibbs T.T., and Farb D.H. Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-d-aspartate receptor. Molecular Pharmacology 40 (1991) 333-336
    • (1991) Molecular Pharmacology , vol.40 , pp. 333-336
    • Wu, F.S.1    Gibbs, T.T.2    Farb, D.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.